Clinical trials: Stomatitis
Aphthous Stomatitis
Safety, Galenic Acceptability and Efficacy of GV-328 Lozenges in Children With Oral Aphthosis
The aim of the study was to assess the safety, acceptability, and efficacy of product GV-328 for the treatment of childhood oral aphthous lesion.
- Trial name
- NCT04677062
- Testing
- GV-328
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses
Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
The investigators' aim is to study the effects of mechanical expression of meibomian glands on eyelid disease, ocular surface health in the subacute phase of SJS/TEN.
- Conditions
- Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses, Ocular Surface Disease, Meibomitis
- Trial name
- NCT05145959
- Testing
- Maskin Probe
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Stomatitis, Aphthous
Treatment of Recurrent Aphthous Stomatitis With Er,Cr:YSGG Laser Irradiation
The aim this study was to investigate the efficacy of Er,Cr:YSGG laser irradiation in reducing pain and on healing rate of recurrent aphthous stomatitis 40 patients with RAS were included to the study.
- Trial name
- NCT02925182
- Testing
- Er,Cr:YSGG Laser
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Denture Stomatitis
The Effectiveness of Palatal Brushing on Denture Stomatitis
Denture stomatitis (DS) is an oral biofilm associated inflammatory disease of the palatal mucosa. It is the most prevalent oral disease and the main indicator of poor oral health among denture wearers, affecting one-third of all…
- Trial name
- NCT02686632
- Testing
- Palatal brushing
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Cutaneous Manifestations, Skin Manifestations
Cutaneous Manifestations of Coronavirus Disease 2019(COVID-19).
An outbreak of Corona virus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-coV-2) occurred in Wuhan city, Hubei province, China in December 2019.
- Conditions
- Cutaneous Manifestations, Skin Manifestations, COVID-19, COVID-19 Pneumonia
- Trial name
- NCT05094687
- Where
- Pakistan
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Canker Sore
Luminance RED for Canker Sores
Canker sores, also called aphthous ulcers, are small, shallow lesions that develop on the soft tissues in your mouth or at the base of your gums.
- Trial name
- NCT04914533
- Testing
- Luminance RED Low Level Laser Therapy Device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- ProofPilot
Recurrent Aphthous Ulcers
The Salivary and Faecal Microbiome of Recurrent Aphthous Stomatitis Patients Before and After Treatment With Probiotics
Recurrent aphthous stomatitis (RAS) is one of the most common ulcerative diseases affecting the oral mucosa. The aetiology remains unknown, but several local, systemic, immunologic, genetic, allergic, nutritional, and microbial…
- Trial name
- NCT02976922
- Testing
- Probiotic lozenge
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Aphthous Stomatitis
Mucoadhesive Film With/without Acmella Oleracea & Triamcinolone Acetonide for Aphthous Ulcers
The purpose of this study is to evaluate the effectiveness of mucoadhesive film with or without Acmella oleracea extract compared to standard treatment by using 0.1% triamcinolone acetonide in pain relief, promoting wound…
- Trial name
- NCT06622213
- Testing
- mucoadhesive film with Acmella oleracea extract, Triamcinolone Acetonide 0.1% Oromucosal Paste, mucoadhesive film without Acmella oleracea extract
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Aphthous Stomatitis
Efficacy and Safety of BALI Association in the Treatment of Aphthous Ulcerations
The purpose of this study is to evaluate the efficacy and safety of BALI association in the treatment of aphthous ulceration.
- Trial name
- NCT05542173
- Testing
- BALI association
- Where
- Brazil
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- EMS
Recurrent Aphthous Ulcer, Recurrent Aphthous Stomatitis
Effectiveness of Recurrent Aphthous Stomatitis Mouthwash System for the Treatment of Oral Ulcers
The purpose of the present research is to evaluate the efficacy of a gel formulation for a total treatment of 14 days for the treatment of traumatic or aphthous oral ulcers.
- Trial name
- RASMA (NCT07121361)
- Testing
- Mouthwash Product, Control
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis
HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-Effectiveness
Severe cutaneous adverse reactions (SCARs), such as Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and drug reaction with eosinophilia and systemic symptoms (DRESS), are rare but life-threatening complications that…
- Conditions
- Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis, Gout and Hyperuricemia
- Trial name
- HLA-SCREEN (NCT07369622)
- Testing
- HLA-B*58:01 Genotyping, Allopurinol Tablet, Febuxostat
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Haiphong University of Medicine and Pharmacy
Oral Ulcer
Clinical Efficiency of Natural Herbal Based Gel.
This clinical trial was conducted in School of Dentistry, Islamabad from 15th June 2023 to 16th January 2024. A total 202 participants took part in study and were divided equally into two groups i.e Control group and Experimental…
- Trial name
- NCT06490289
- Testing
- Denpro oral gel
- Where
- Pakistan
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Oral Mucositis, Quality of Life
Thalidomide With or Without Probiotics in Radioactive Oral Mucositis
Study on the application of thalidomide with or without probiotics in radioactive oral mucositis
- Trial name
- NCT05059613
- Testing
- probiotics
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jiangxi Provincial Cancer Hospital
Oral Ulcer
Basil Extract (Ocimum Basilicum) in the Management of Recurrent Aphthous Stomatitis
A randomized double-blind placebo controlled trial will be carried out on 20 patients complaining from aphthus ulcer and 10 patient healthy control 10 patients treated with mucoadhesive gel containing 2% of basil extract 4 times…
- Trial name
- RCT (NCT04710888)
- Testing
- use of basil extract gel in treatment of aphthus ulcer, no treatment
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Oral Aphthous Ulcer
Clinical Evaluation of Topical Coenzyme Q10 in Management of Oral Aphthous Ulcer
Recurrent oral aphthous ulcer is the most common oral lesion in occurrence and one of cause is oxidative stress so investigators need to use antioxidant drugs like topical coenzyme Q10 gel to treat the lesion and more safe for…
- Trial name
- NCT03213769
- Testing
- topical coenzyme Q10 gel, Carpabol gel
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Stomatitis
Effectiveness of Hygiene Solutions on Denture Biofilm
This clinical trial evaluated Ricinus communis and sodium hypochlorite solutions in different concentrations for denture cleanliness, regarding biofilm removal capacity, remission of atrophic chronic candidiasis, degree of…
- Trial name
- NCT02407834
- Testing
- S1, S2, S3
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Denture Stomatitis
Clinical and Microbial Study of Reinforced 3D Printed Maxillary Denture Base Resin
Statement of problem: 3D printed denture base resin is needed to reinforce Purpose: To evaluate the effects of adding nano-ZrO2 and nano-TiO2 on microbial colonization and patient satisfaction with 3D-printed maxillary complete…
- Trial name
- dimensions (NCT06921577)
- Testing
- antimicrobial agent
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanta University
Inflammatory Response, Microbial Colonization
Microbial Adhesion and Biofilm Formation on Denture Base Materials
Polymethylmethacrylate (PMMA) has been the material of choice for fabricating complete dentures for more than 80 years now.(1,2) As a material it is easy to handle and can be easily repaired and polished.
- Conditions
- Inflammatory Response, Microbial Colonization, Denture Stomatitis
- Trial name
- NCT06395116
- Testing
- Denture base material
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Minor Recurrent Aphthous Stomatitis Lesions
The Effect of 2-DeNT Oral Topical Powder on Minor Recurrent Aphthous Ulcer
This is a prospective, randomized, blinded, placebo-controlled, crossover clinical trial to evaluate the efficacy of 2-DeNT oral topical powder in the treatment of recurrent aphthous stomatitis (RAS).
- Trial name
- NCT02142543
- Testing
- 2-DeNT powder
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Recurrent Aphthous Stomatitis
A Study on Sumac Mouth Rinse for Treating Recurrent Aphthous Stomatitis
This randomized controlled clinical study aims to evaluate the effectiveness of a Sumac mouth rinse in the management of recurrent aphthous stomatitis (RAS).
- Trial name
- SUMAC-RAS (NCT07229469)
- Testing
- Sumac mouth rinse, Tantum Verde mouth rinse
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ain Shams University