Clinical trials: Stomatognathic Disease
Gingival Recession
The Efficacy of De-epithelialized Free Gingival Graft on Treatment of Multiple Gingival Recessions With Tunnel Technique
The predictable treatment of multiple adjacent gingival recessions (MAGRs) represents a major challenge in periodontal plastic surgeries due to MAGRs' complicated predisposing anatomic features, such as thin gingival phenotype or…
- Trial name
- NCT04291963
- Testing
- DGG + TUN, SCTG + TUN
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Gazi University
Edentulous Jaw
Adjunctive Benefit of Xenograft Plus a Membrane During Sinus Crestal Approach
Patients in need for implant-supported restoration in maxillary posterior sites with insufficient residual bone height will be randomly allocated to two different arms.
- Trial name
- NCT04662333
- Testing
- Transcrestal approach for sinus lift, Xenograft application
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Siena
Irreversible Pulpitis With Apical Periodontitis
Full Pulpotomy in Permanent Teeth With Irreversible Pulpitis and Apical Periodontitis
This study will evaluate whether full pulpotomy can successfully treat mature permanent teeth with irreversible pulp inflammation and a periapical lesion.
- Trial name
- NCT07768852
- Testing
- Full pulpotomy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Caries
An in Vitro Evaluation of Antimicrobial Photodynamic Therapy on Deciduous Carious Dentin
Despite of the decline of dental caries, this disease is still common in polarized groups affecting children. Therefore, the aim of this randomized blind in vivo study was to compare the antimicrobial effect of two antimicrobial…
- Trial name
- NCT02479958
- Testing
- Rubber dam isolation, Tooth drying, Dentin wash with chlorhexidine 2%
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pulpitis
Oral Glucocorticoids Effect on Post Endodontic Pain
The aim of this single-center randomized, double-blind, placebo-controlled clinical trial is to assess the effect of preoperative, single, oral dose of prednisolone on postoperative pain and medication intake in patients with…
- Trial name
- NCT02819648
- Testing
- Prednisolone, Control
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Diseases, Coronary Artery Disease
Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Generalized Chronic Periodontitis Subjects
Quantification of NLRP3 (rs4612666) and CARD8 (rs20432111) will be analysed in the subgingival plaque and blood samples of generalized chronic periodontitis with and without coronary heart disease.
- Trial name
- NCT04127487
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Periodontitis
The Effect of Time on the Outcome of Periodontal Treatment.
Re-evaluation after non-surgical periodontal treatment remains an integral part of comprehensive periodontal therapy. This re-evaluation determines if a patient is in need either of surgical periodontal therapy or a personalized…
- Trial name
- NCT05643287
- Testing
- Periodontal treatment
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- 251 Hellenic Air Force & VA General Hospital
Tonsillitis
Influence of 0.75% Ropivacaine Topicalization on Emergence Agitation in Children
Emergence agitation (EA) is highly prevalent in children after surgery. Risk factors for EA are Eye, nose and throat (ENT) surgery, preoperative anxiety, postoperative pain.
- Trial name
- NCT02848287
- Testing
- normal saline, ropivacaine
- Volunteers
- 84 people
- Sponsor
- Ajou University School of Medicine
Complement Mediated Diseases
First-In-Human Clinical Study of the C3 Complement Inhibitor AMY- 101 in Healthy Male Volunteers
Safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of a Single Ascending Dose (SAD) and a Multiple Dose (MD) of the complement inhibitor AMY-101.
- Trial name
- NCT03316521
- Testing
- AMY-101
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Amyndas Pharmaceuticals S.A.
Oral Cancer, Reconstructive Surgery
App-Assisted Swallowing Program After Oral Cancer Surgery
This study aims to examine the effects of a swallowing care program combined with an exercise mobile application (App) on swallowing function, anxiety, and quality of life in patients with oral cancer after flap reconstruction…
- Conditions
- Oral Cancer, Reconstructive Surgery, Postoperative
- Trial name
- AASP (NCT07301047)
- Testing
- Swallowing Care + Exercise App, Routine Postoperative Care
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- Chang Gung Memorial Hospital
Head and Neck Cancer, Oral Mucositis
Edible Plant Exosome Ability to Prevent Oral Mucositis Associated With Chemoradiation Treatment of Head and Neck Cancer
This study will evaluate the ability of grape exosomes, given to the subject as grape powder, as an important anti-inflammatory agent to reduce the incidence of oral mucositis during radiation and chemotherapy treatment for head…
- Trial name
- NCT01668849
- Testing
- Grape extract, Lortab, Fentanyl patch, mouthwash
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Louisville
Renal Cancer, Renal Clear Cell Carcinoma
CD70-targeted immunoPET Imaging of Malignant Cancers
This study aims to determine the value of cluster of differentiation (CD70)-targeted immuno-positron emission tomography/computed tomography (immunoPET/CT) imaging for diagnosing human malignancies, including renal cell carcinoma…
- Conditions
- Renal Cancer, Renal Clear Cell Carcinoma, Lymphoma, Lymphoma, Large B-Cell, Diffuse
- Trial name
- NCT06852638
- Testing
- [18F]F-RESCA-RCCB6, [18F]F-RESCA-R8B4, [68Ga]Ga-NOTA-R8B4
- Where
- China
- Volunteers
- 300 people
- Sponsor
- RenJi Hospital
Temporomandibular Disorders (TMD), Sleep
ASSOCIATION BETWEEN TEMPOROMANDIBULAR DISORDERS AND SLEEP DISORDERS
ASSOCIATION BETWEEN TEMPOROMANDIBULAR DISORDERS AND SLEEP DISORDERS
- Trial name
- Gnathology TMD (NCT06975709)
- Testing
- Questionnaire and Physical Exam
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Head and Neck Cancer, Oral Complications
Sargramostim in Decreasing Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer
RATIONALE: Sargramostim may lessen symptoms of mucositis in patients receiving radiation therapy for head and neck cancer. It is not yet known if sargramostim is more effective than no treatment in reducing mucositis caused by…
- Conditions
- Head and Neck Cancer, Oral Complications, Radiation Toxicity
- Trial name
- NCT00008398
- Testing
- sargramostim, quality-of-life assessment, radiation therapy
- Where
- 236 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group
Discoloration of Teeth
Determination of a Threshold for Mouth Rinse Induced Discoloration of Teeth
The purpose of this study is to daily monitor the discoloration of teeth when participants rinse with a mouth rinse and black tea and to determine the time point when unacceptable discoloration occurs.
- Trial name
- NCT01382914
- Testing
- chlorhexidine 0.12%
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Dentin Sensitivity
Study to Investigate the Efficacy of an Occluding Dentifrice in Providing Relief From Dentine Hypersensitivity
This will be a single centre, two week, randomised, examiner blind, two treatment arm, parallel design, stratified (by maximum baseline Schiff sensitivity score of the two selected test teeth), controlled study, in participant…
- Trial name
- NCT02773758
- Testing
- Stannous Fluoride Dentifrice, Sodium monofluorophosphate Dentifrice
- Where
- Canada
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Bell Palsy
Effect of Neural Mobilization in Bells Palsy: A Randomized Controlled Trial
Bells palsy is a sudden paralysis of half of the facial muscle. The BP is idiopathic and 70% responds well with drug therapy. There are many complementary therapies such as , tapping, electrical stimulation, and massage that adds…
- Trial name
- NCT04280120
- Testing
- Neural Mobilisation, Massage therapy, Faradic electrical stimulation
- Where
- 2 sites in India
- Volunteers
- 62 people
- Sponsor
- Majmaah University
Dental Wear
Hybrid Ceramic on Worn Dentition Patients
Evaluation of hybrid composite-nanoceramic on material characteristic and clinical use over tooth wear patients.
- Trial name
- NCT04775823
- Testing
- Hybrid composite nano-ceramic
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Malocclusion, Angle Class II, Malocclusion
Mandibular Response After Maxillary Orthopedic Expansion in Class II Growing Subjects
the effectiveness of RME (Rapid Maxillary Expander) on the sagittal dental or skeletal parameters is still controversial because very little has been written regarding the behavior of antero-posterior mandibular changes in Class…
- Trial name
- NCT03159962
- Testing
- Bonded RME (Rapid Maxillary Expander) appliance, Banded RME (Rapid Maxillary Expander) appliance
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Rome Tor Vergata
Edentulism, Tooth Loss
5-Years PMCF Study of Ceramic Dental Implants One-piece Versus Two-piece.
The goal of this cohort observational study is to compare in the survival rate of ceramic dental implants placed in patients with missing or hopeless teeth .
- Trial name
- 240101 (NCT06287346)
- Testing
- dental implant
- Where
- 2 sites in United States, Spain
- Volunteers
- 652 people
- Sponsor
- CeraRoot SL
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