Clinical trials: Stomatognathic Disease
Cardiovascular Diseases, Periodontitis
Effects of Non-surgical Periodontal Therapy on Cardiovascular Risk
This study is to evaluate whether non-surgical periodontal therapy can help to control the cardiovascular risk among patients with moderate/severe periodontitis and at risk of cardiovascular disease.
- Trial name
- NCT05459727
- Testing
- Non-surgical periodontal therapy, Control periodontal treatment
- Where
- 2 sites in China
- Volunteers
- 376 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Gingival Recession Generalized Moderate
The Use of Coronary Displaced Flap and Deepithelialized Free Graft in the Treatment of Multiple Gingival Recessions
Successful treatment of multiple gingival recessions (MRG) is a major challenge in periodontal plastic surgery due to complicated predisposing anatomical features of the surrounding tissues, such as a thin gingival phenotype or a…
- Trial name
- NCT05664373
- Testing
- Coronally advanced flap and deepithelized free gingival graft
- Where
- Serbia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Graft Vs Host Disease, Oral Mucositis (Ulcerative)
Treatment of Oral Mucositis Using Platelet Rich Fibrin TREATMENT OF ORAL MUCOSITIS USING PRF
Oral mucositis (OM) is an inflammatory mucosal demolition frequently observed during treatments for neoplastic diseases such as chemotherapy or radiation therapy.
- Conditions
- Graft Vs Host Disease, Oral Mucositis (Ulcerative), Mesenchymal Stem Cells
- Trial name
- NCT05018754
- Testing
- TREATMENT OF ORAL MUCOSITIS USING PLATELET-RICH-FIBRIN (PRF)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Rome Tor Vergata
Oral Mucosal Disease
Clinical Research Core Dental Screening Protocol
This study will screen patients for eligibility in studies sponsored by the Craniofacial Genetics Section (HCGS), the Clinical Research Core (CRC), and other branches located within the National Institute of Dental and…
- Trial name
- NCT00090818
- Where
- United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Peri-Implantitis, Dental Implant Failed
Assessment of the Effects of Different Implant Abutment Occluding Materials on Dental Implant Health Parameters and Microbiology
The primary purpose of this study is to determine what effect, if any, do different dental materials used to seal the prosthetic screw channels of implant supported restorations have on dental implant health parameters and…
- Conditions
- Peri-Implantitis, Dental Implant Failed, Dental Implant Failure Nos
- Trial name
- NCT02625597
- Testing
- Cotton Pellet, Polytetrafluoroethylene Tape, Synthetic Foam
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Facial Asymmetry, Retrognathism
Efficacy of Intravenous Iron Therapy in Maintaining Hemoglobin Concentration on Patients Undergoing Bimaxillary Orthognathic Surgery
The aim of this study is to evaluate the effect of Intravenous iron isomaltoside on maintaining hemoglobin concentration in patients undergoing bimaxillary orthognathic surgery.
- Conditions
- Facial Asymmetry, Retrognathism, Prognathism
- Trial name
- NCT03094182
- Testing
- Iron Isomaltoside 1000, Normal saline
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Bruxism
mRNA Expression and Genetic Polymorphisms Affecting DRD3 (rs6280) and HTR2A (rs6313) in Bruxism
The goal of this observational study is to learn about the genetic factors influencing bruxism, a condition characterized by teeth grinding, in a group of participants.
- Trial name
- NCT06457646
- Testing
- Genetic polymorphism
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Nasopharyngeal Carcinoma, Intensity-Modulated Radiotherapy
Reducing High Risk Primary Tumor Clinical Target Volumes (CTVp1) in Non-metastatic Nasopharyngeal Carcinoma
To evaluate the long-term local control, survival rate, acute and late radiation related toxicities, quality of life after reducing high risk primary tumor clinical target volumes (CTVp1) in non-metastatic nasopharyngeal…
- Trial name
- CTVp1-NPC (NCT05994170)
- Testing
- Reduction CTVp1, Non-reduction CTVp1
- Where
- China
- Volunteers
- 454 people
- Sponsor
- Zhongshan People's Hospital, Guangdong, China
Behcet's Disease
Special Investigation in Patients With Intestinal Behcet's Disease (All Case Investigation)
This investigation was conducted to obtain the following information regarding the use of Adalimumab (Humira®) 40mg Syringe 0.8mL for Subcutaneous Injection in patients with Intestinal Behcet's Disease. 1.
- Trial name
- NCT01960790
- Volunteers
- 473 people
- Sponsor
- AbbVie
Periodontitis, Peri-Implantitis
Periodontitis and Inflammation
Today, to understand pathogenic mechanisms involved in periodontitis and peri-implantitis remains a challenge to identify biomarkers or therapeutic targets to improve prevention and screening, as well as the effectiveness of…
- Trial name
- CB-PARO (NCT04831060)
- Testing
- Periodontal or peri-implantitis treatment, Control treatment
- Where
- 2 sites in France
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Steven-Johnson Syndrome, Toxic Epidermal Necrolysis
Severe Cutaneous Adverse Reactions in Thailand
The multicenter registry of patients with severe cutaneous adverse reactions among tertiary medical institutes in Thailand to study clinical characteristics, etiologies, therapeutic outcomes, quality of life, and the values of in…
- Conditions
- Steven-Johnson Syndrome, Toxic Epidermal Necrolysis, Drug Reaction With Eosinophilia and Systemic Symptoms, Acute Generalized Exanthematous Pustulosis
- Trial name
- ThaiSCAR (NCT02574988)
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Chulalongkorn University
Sarcopenia, Sjogren's Syndrome
Prevalence and Factors of Sarcopenia and in Patients With Primary Sjogren's Syndrome
Sarcopenia is a progressive condition characterized by decline in muscle strength and muscle mass. Although the mechanism of sarcopenia has not been fully elucidated, it may be caused by protein-poor diet, vitamin D deficiency…
- Conditions
- Sarcopenia, Sjogren's Syndrome, Rheumatologic Disease
- Trial name
- NCT05015114
- Testing
- Sarcopenia Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Acibadem University
Postoperative Nausea and Vomiting, Sore-throat
Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?
The aim of this study is to investigate the effect of throat packs on PONV in dental treatments under general anesthesia in special health care needs.
- Conditions
- Postoperative Nausea and Vomiting, Sore-throat, Dental Caries
- Trial name
- NCT06169306
- Testing
- throat pack
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Tonsillitis, Streptococcus Pharyngitis
Antimicrobial Stewardship Program (ASP) in Patients With a Sore Throat
The investigators have developed an antibiotic stewardship program (ASP) to increase adherence to the Swedish guidelines for managing patients with a sore throat.
- Conditions
- Tonsillitis, Streptococcus Pharyngitis, Sore Throat, Pharyngitis
- Trial name
- ASP-Throat (NCT03408704)
- Testing
- ASP
- Where
- Sweden
- Volunteers
- 49 people
- Sponsor
- Vastra Gotaland Region
Tongue Cancer, Chemotherapy Effect
A Study of Tongue Conservation Surgery for Oral Tongue Cancer
This is an open-label, non-comparative phase II clinical trial to assess efficacy and safety of tongue conservation treatment with sequential induction chemotherapy, tongue conservation surgery and postoperative concurrent…
- Conditions
- Tongue Cancer, Chemotherapy Effect, Surgery
- Trial name
- NCT03161548
- Testing
- Induction chemotherapy, Tongue conservation surgery, postoperative CCRT
- Volunteers
- 23 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Sedation, ICU
RemImazolam Besylate for ICU-sedation in Patients With Mechanical Ventilation After Oral and Maxillofacial Surgery
Remimazolam besylate, as a new benzodiazepine drug, showing rapid clearance and moderate distribution of pharmacokinetic changes.
- Conditions
- Sedation, ICU, Remimazolam Besylate
- Trial name
- NCT05606315
- Testing
- Remimazolam Besylate, Propofol, Midazolam
- Where
- 2 sites in China
- Volunteers
- 117 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Mucositis Oral
Evaluation of ONCOXIN® in Oral Mucositis, Appetite and Body Mass in Cancer Patients.
Oral mucositis is one of the most spread side effects of anticancer therapy. It is associated with both chemo- and radiotherapy, decreases QoL, relative dose intensity and leads to nutritive deficiency.
- Trial name
- NCT03577535
- Testing
- Oncoxin®
- Where
- Russia
- Volunteers
- 15 people
- Sponsor
- Catalysis SL
Temporomandibular Disorders (TMD)
Age and Gender in TMJ Sounds
The temporomandibular joint (TMJ) plays a crucial role in masticatory function, and its proper lubrication is essential for smooth, frictionless movement.
- Trial name
- NCT06871189
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Atlas University
Mucositis
Impact of Oral Hygiene Gels on Peri-implant Mucositis
Peri-implant mucositis is abnormal inflammation occurring around dental implants, increasing the risk of loss of bone support. The purpose of this study is to evaluate the impact of brushing the bacterial biofilm at the…
- Trial name
- NCT03243591
- Testing
- Livionex gel, Aquafresh gel
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Coronary Heart Disease, Periodontal Diseases
Expression of Trefoil Factors and Adrenomedullin in Subjects With Chronic Periodontitis and Coronary Heart Disease
To assess the demographic variables, periodontal parameters and to determine the expression of Trefoil factors 2 and 3 and Adrenomedullin in unstimulated saliva samples of periodontally healthy subjects with coronary heart…
- Trial name
- NCT04127474
- Where
- India
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
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