Clinical trials: Stomatognathic Diseases
Gingival Recession Types One(RT1), Gingival Crevicular Fluid
Comparison of Connective Tissue and PRF in Gingival Recession
Aim: In this study, it was aimed to comparatively investigate the clinical and biochemical effects of subepithelial connective tissue graft and coronally advanced flap (SCTG + CAF) or titanium-prepared platelet rich fibrin and…
- Trial name
- NCT07877064
- Testing
- Titanium-prepared Platelet-Rich Fibrin, SCTG + CAF
- Volunteers
- 22 people
- Sponsor
- Ataturk University
Gingivitis, Periodontitis
EFFECTIVENESS OF ORAL HYGIENE INSTRUCTIONS GIVEN BY AI-GENERATED VIDEOS VS. TRADITIONAL APPROACH IN PERIODONTAL PATIENTS
Patients attending Dubai Dental Hospital and requiring nonsurgical periodontal therapy will be invited to take part in the study.
- Trial name
- OHI (NCT06622863)
- Testing
- Standard oral hygiene instructions will be given verbally by the periodontics resident, Avatar-based group will receive oral hygiene instructions from a digital avatar of their choice
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Dental Plaque, Bleeding of Subgingival Space
Antibacterial Photodynamic Therapy as an Adjunctive Treatment on Oral Hygiene in Elderly Persons
On average, the dental condition of elderly people is poor due to various reasons. The importance of oral health maintenance of the ageing population has been recognized by the World Health Organization (WHO), as oral health…
- Conditions
- Dental Plaque, Bleeding of Subgingival Space, Oral Complication
- Trial name
- NCT06576063
- Testing
- Lumoral Treatment, Standard oral hygiene methods
- Where
- 3 sites in Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Koite Health Oy
Nasopharyngeal Carcinoma, Radiation-induced Xerostomia
Impact on Xerostomia for Nasopharyngeal Carcinoma Patients Treated With or Without Superficial Parotid Lobe-sparing Intensity-modulated Radiotherapy
This is a prospective phase II clinical randomized controlled study, the purpose of this study is to assess whether superficial parotid lobe-sparing intensity-modulated radiotherapy (SPLS-IMRT) can decrease the incidence of…
- Trial name
- NCT05020067
- Testing
- superficial parotid lobe-sparing intensity-modulated radiotherapy
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Sun Yat-sen University
Temporomandibular Disorder
Low-level Laser Therapy on Temporomandibular Disorder
The purpose of this study is to assess the effect of low-level laser on pain, occlusal contacts, mandibular movements and electromyography activity in the masseter and temporal muscles in adolescents with TMD.
- Trial name
- NCT01846000
- Testing
- low-level laser treatment
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- University of Nove de Julho
Dental Pulp Necroses, Apical Periodontitis
Effects of Intracanal Cryotherapy on Endodontic Postoperative Pain
The goal of this clinical trial is to evaluate the effect of cold saline (2.5 degrees Celsius) irrigation on postoperative pain in patients who require root canal treatment in molar teeth because of dead dental pulp and infection…
- Conditions
- Dental Pulp Necroses, Apical Periodontitis, Post Operative Pain
- Trial name
- NCT05611736
- Testing
- cold saline, saline
- Where
- Saudi Arabia
- Volunteers
- 302 people
- Sponsor
- Qassim University
Head and Neck Cancer, Oropharyngeal Cancer
Robotic Assisted Surgery in Upper Aerodigestive Tract Surgery
To evaluate the use of the daVinci Robotic System for better visibility and access of head and neck lesions and decreased amount of surgery time.
- Conditions
- Head and Neck Cancer, Oropharyngeal Cancer, Hypopharyngeal Cancer, Upper Aerodigestive Tract Neoplasms
- Trial name
- NCT00473564
- Testing
- da Vinci® Robotic System
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- University of Alabama at Birmingham
Tongue Neoplasms, Carcinoma
Therapeutic Effect Of Luteolin Natural Extract Versus Its Nanoparticles On Tongue Squamous Cell Carcinoma Cell Line
In vitro study to examine whether luteolin and nano-luteolin exert an inhibitory effect on tongue squamous cell carcinoma cell line by inducing apoptosis, and to assess if nano-luteolin has more efficient apoptotic activity than…
- Trial name
- NCT03288298
- Testing
- luteolin, nano-luteolin
- Volunteers
- 4 people
- Sponsor
- Cairo University
Drug/Agent Toxicity by Tissue/Organ, Head and Neck Cancer
Chemotherapy Plus Radiation Therapy With or Without Amifostine in Treating Patients With Locally Advanced Cancer of the Nasopharynx
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Conditions
- Drug/Agent Toxicity by Tissue/Organ, Head and Neck Cancer, Oral Complications, Radiation Toxicity
- Trial name
- NCT00025298
- Testing
- amifostine trihydrate, carboplatin, cisplatin
- Where
- 13 sites in Belgium, France and 4 more
- Volunteers
- 5 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Temporomandibular Disorders (TMD)
The Effect of Non-Invasive Vagal Nerve Stimulation Combined With Self-Managed Therapy in Individuals With Myogenic Temporomandibular Dysfunction
The aim of our study is to determine the benefit of non-invasive Vagal Nerve Stimulation in combination with self-administered therapy on the symptoms associated with jaw joint dysfunction in individuals with jaw joint…
- Trial name
- NCT06802445
- Testing
- Self-Management Therapy, Non-Invasive Vagal Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Toros University
Nasopharyngeal Carcinoma
HepaSphere Interventional Therapy Using Digital Subtraction Angiography（DSA） for Nasopharyngeal Carcinoma
The purpose of this study is to evaluate the safety and efficacy of HepaSphere interventional therapy using digital subtraction angiography（DSA） for nasopharyngeal carcinoma.
- Trial name
- NCT02523430
- Testing
- interventional therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Dentofacial Deformities
Custom Titanium Plates vs. 3D Splints in LeFort I Osteotomy
This randomized comparative study evaluates the accuracy and feasibility of two techniques for maxillary repositioning in Le Fort I osteotomy: Customized titanium plates (splintless technique) Three-dimensional (3D)-printed…
- Trial name
- NCT06933628
- Testing
- Patient-Specific Titanium Plates, 3D-Printed Intermediate Splint
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Al-Azhar University
Oral Lichen Planus
A Randomized Clinical Trial of the Effect of Pimecrolimus Cream 1% Compared With Topical Corticosteroid in Treatment of Erosive Oral Lichen Planus
The purpose of this study is to compare the effect of topical Pimecrolimus with adcortyl on erosive-atrophic 0ral lichen planus in a randomized clinical trial study.
- Trial name
- NCT01524744
- Testing
- Pimecrolimus ointment, Adcortyl
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Mashhad University of Medical Sciences
Bell Palsy
MIME THERAPY vs MOTOR IMAGERY TECHNIQUE in Bell's Palsy
Bell's palsy, characterized by unilateral paralysis/paresis of facial muscles, is a condition with a significant impact on individuals' lives.
- Trial name
- NCT06340009
- Testing
- mime therapy, motor imagery
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Hand, Foot and Mouth Disease
A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of Hand, Foot, and Mouth Disease
The study is aimed to evaluate the effectiveness and safety of traditional Chinese medicine (TCM) for treatment of hand, foot, and mouth disease (HFMD).
- Trial name
- NCT01182532
- Testing
- Western therapy, TCM Syndrome Differentiation and Treatment, Western therapy plus TCM treatment
- Where
- 21 sites in China
- Volunteers
- 3,000 people
- Sponsor
- The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine
HIV Infections
Effect of an Anti-Inflammatory Drug on Gut Mucosa in HIV Infected Patients
The lining of the gastrointestinal tract contains specialized lymphoid tissue that is part of the immune system. Like other parts of the immune system, HIV attacks this lymphoid tissue.
- Trial name
- NCT00069498
- Testing
- 5-aminosalicylic acid
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Dental Caries
Parental Knowledge, Attitude and Practice Towards Oral Health of Their Children
The aim of this study is to assess the parental knowledge, attitude and practice towards oral health of their children in relation to caries experience.
- Trial name
- NCT04571931
- Volunteers
- 367 people
- Sponsor
- Cairo University
Tongue Cancer
Radiotherapy of Tongue Cancer Using an Intraoral Stent
Radiotherapy of tongue cancer is associated with acute and late morbidity. Use of an intraoral stent will provide a larger distance between the tongue and palate and can reduce side-effects.
- Trial name
- NCT04337853
- Testing
- Intraoral stent, No intraoral stent
- Where
- Norway
- Volunteers
- 13 people
- Sponsor
- Oslo University Hospital
Alveolar Osteitis, Dry Socket
Treatment of Alveolar Osteitis: Traditional or Regenerative?
Alveolar osteitis, commonly referred to as dry socket, is a common painful postoperative complication following tooth extraction.
- Conditions
- Alveolar Osteitis, Dry Socket, Pain, Healing
- Trial name
- NCT05615272
- Testing
- Bio-PRF, Alveogyl
- Where
- Ireland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Biomarkers, Saliva
Application of Salivary Biomarkers in Risk Assessment for Oral Diseases in Children With Type 1 Diabetes
This research contributes to a deeper understanding of the etiopathogenesis of periodontal and other oral diseases in children with T1D.
- Conditions
- Biomarkers, Saliva, Type 1 Diabetes (T1D), Dental Care for Children
- Trial name
- NCT06924372
- Testing
- Taking saliva samples of unstimulated saliva will be collected in sterile containers, salivets., Dental status, Periodontal status
- Where
- Serbia
- Volunteers
- 112 people
- Sponsor
- University of Novi Sad
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