Clinical trials: Stomatognathic System
Candidiasis, Esophageal, HIV Infections
Evaluation of Amphotericin B in the Treatment of Biopsy Proven Candida Esophagitis in Immunocompromised Patients
To determine the appropriate duration of amphotericin B therapy for Candida esophagitis. To compare the effectiveness of two different amphotericin B doses in the treatment of biopsy-proven Candida esophagitis.
- Trial name
- NCT00002041
- Testing
- Amphotericin B
- Where
- United States
- Sponsor
- Bristol-Myers Squibb
Dental Implants, TNF-alpha Inhibitors
Dental Implant Healing With TNF-Alpha Inhibitors
The goal of this pilot study is to learn about healing after dental implant placement in patients taking a class of biologic drug called Tumor Necrosis Factor or TNF-alpha antagonist or inhibitor.
- Conditions
- Dental Implants, TNF-alpha Inhibitors, Edentulism
- Trial name
- NCT06538870
- Testing
- Placement of dental implants
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Mucositis Oral
A Clinical Trial of the Administration of Light Therapy to Prevent Mouth Sores in Children With Cancer
The goal of this clinical trial is to learn if light therapy can prevent mouth sores in children with cancer. The main questions it aims to answer are: Is it reasonable and acceptable to provide light therapy for children with…
- Trial name
- PBM (NCT06623305)
- Testing
- Photobiomodulation for prevention arm, Photobiomodulation for exploratory arm
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medical College of Wisconsin
Class I Malocclusion, Class II Div 1 Malocclusion
Assesment of Ethnic Bias in an Artificial Intelligence Based Orthodontic Diagnosis System
This study explores how artificial intelligence (AI) can be used in orthodontics, which is the area of dentistry that focuses on correcting jaw and bite problems.
- Conditions
- Class I Malocclusion, Class II Div 1 Malocclusion, Class II Division 2 Malocclusion, Class III Malocclusion
- Trial name
- NCT07162753
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Cleft Lip and Palate
Rapid Maxillary Expansion and Protraction by Expander Differential Opening EDO in Cleft Lip and Palate Patients
maxillary expansion in cleft palate patient with expander and using face mask.
- Trial name
- NCT05009472
- Testing
- expander with deferential opening and petit face mask
- Where
- 2 sites in Egypt
- Volunteers
- 10 people
- Sponsor
- Faculty of Dental Medicine for Girls
Schizophrenia, Micrognathia
The Relevance Between the microRNA-30e in Plasma and the Prognosis of Schizophrenia Patients
This study investigates the relationship of circulating microRNA-30e and schizophrenia, and shows the relevance of the aberrant microRNA-30e expression in plasma with the variation disease status.
- Trial name
- NCT03007303
- Testing
- Atypical Antipsychotic, atypical antipsychotic combined with MECT
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dalian Seventh People's Hospital
Pain, Mucositis
Topical Morphine for Stomatitis-related Pain Induced by Chemotherapy
Stomatitis/oral mucositis is a common side effect to chemotherapy. Stomatitis is often associated with painful ulcers in the mouth.
- Trial name
- NCT00357942
- Testing
- morphine solution for injection, morphine mouthwash
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Danish University of Pharmaceutical Sciences
Cleft Lip, Cleft Palate
Characterization of Cleft Lip and Palate Conditions in Guatemala
The purpose of this study is to compare types of and risk factors for cleft lip and palate in a Guatemalan population to a United States population.
- Conditions
- Cleft Lip, Cleft Palate, Cleft Lip and Palate
- Trial name
- NCT04725370
- Testing
- NA - survey instrument
- Where
- United States
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Meibomian Gland Dysfunction, Dry Eye Syndromes
Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic Patients
This observational study aims to assess the frequency and severity of Meibomian Gland Dysfunction (MGD) and associated ocular surface changes in patients with systemic autoimmune rheumatic diseases compared with healthy…
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Syndromes, Rheumatoid Arthritis, Systemic Lupus Erythematosus
- Trial name
- NCT07810569
- Volunteers
- 150 people
- Sponsor
- Assiut University
HIV Infections, Stomatitis, Aphthous
Thalidomide for Treatment of Oral and Esophageal Aphthous Ulcers and HIV Viremia in Patients With HIV Infection
PRIMARY: To evaluate the effectiveness and safety of thalidomide for treatment of oral and esophageal aphthous ulcers (those unrelated to a known infection or malignancy) in patients with advanced HIV disease.
- Trial name
- NCT00000790
- Testing
- Thalidomide
- Where
- 40 sites in United States, Puerto Rico
- Volunteers
- 164 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Bruxism, Myopathy
Reduction of Masticatory Muscle Activity by Restoring Canine Guidance
In this study it is to be evaluated wether a restoration with composite resin fillings to reestablish a canine guidance will reduce masticatory muscle activity in patients with bruxism.
- Conditions
- Bruxism, Myopathy, Muscular Activity
- Trial name
- NCT02235220
- Testing
- Composite resin restoration
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Kiel
Nasopharyngeal Carcinoma (NPC)
Validation of the 9th AJCC Staging System for NPC in Non-High-Incidence Areas in China
Background: Nasopharyngeal carcinoma (NPC) is a malignancy with marked geographic variation, with over 80% of global cases found in Southeast and East Asia.
- Trial name
- NCT07088861
- Volunteers
- 1,401 people
- Sponsor
- Lirong Wu
Molar Incisor Hypomineralization
Effect of Enamel Cleaning on a Remineralizing Paste for Hypomineralizated Lesions
Molar-incisor hypomineralization (MIH) is a qualitative defect of dental enamel, in which low mineral content and high protein content compromise the effectiveness of remineralizing treatments.
- Trial name
- ECLIPSE (NCT07653373)
- Testing
- Sodium hypochlorite 5.25%, CPP-ACPF
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade Ceuma
Cleft Palate
Using of Acellular Dermal Matrix in Cleft Palatal Fistula and Compare With Use of Conchal Cartolage
The fact that still exist is which method for repairing of secondary cleft palatal fistula is the best. This study will have shown whether using of Acellular dermal Matrix decreased the fistula formation versus using Conchal…
- Trial name
- NCT03170505
- Testing
- repairing fistula
- Volunteers
- 60 people
- Sponsor
- Isfahan University of Medical Sciences
Facial Nerve Palsy
The Role of a Device to Evaluate the Neuromuscular Function in Assessing Muscle in Facial Paralysis Patients
The objective of the research is to determine whether the MyotonPRO has a valid and reliable application in facial, head and neck surgery. In addition, the study aims to compare this new technology with current electromyography.
- Trial name
- MyotonPRO (NCT02489162)
- Testing
- MyotonPRO, non-invasive electromyography (EMG)
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Non-Hodgkin's Lymphoma, Multiple Myeloma
PROMPT - Palifermin in Reduction of Oral Mucositis in PBSC Transplantation
This is an open-label, single-arm, multicentre study conducted in Spain to estimate the effectiveness of palifermin administered at a dose of 60 mg/kg/day IV for 3 consecutive days before the start of the conditioning regimen and…
- Trial name
- NCT00352703
- Testing
- Kepivance (Palifermin)
- Volunteers
- 145 people
- Sponsor
- Swedish Orphan Biovitrum
Sleep Bruxism
Evaluation of Muscle Activity, Bite Force and Salivary Cortisol in Children With Bruxism
Bruxism is a repetitive activity of the masticatory muscles characterized by grinding and/or clenching one's teeth or parafunctional movements of the mandible.
- Trial name
- Bruxism (NCT02757261)
- Testing
- Laser, Occlusal splint
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Gingivitis; Chronic
Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With Gingivitis
This pilot study aims to evaluate the effects of miswak use on the oral biological environment by comparing biochemical parameters obtained from saliva and dental plaque samples collected from individuals who use miswak and…
- Trial name
- NCT07689786
- Testing
- Miswak, Toothpaste
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Neonatal Lupus, Systemic Lupus Erythematosus
The Research Registry for Neonatal Lupus
Women with lupus and other related disorders produce certain antibodies in the blood. Some women have these antibodies even if they have not yet developed symptoms of lupus or Sjogren's syndrome.
- Conditions
- Neonatal Lupus, Systemic Lupus Erythematosus, Sjogren's Syndrome, Congenital Heart Block
- Trial name
- NCT00074373
- Testing
- No intervention; observational
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Pain, Local Infiltration
Pain Perception With a Comfort-ın Jet Injection and Conventional Dental Injection
The investigators aimed to compare the effectiveness of the Comfort-in system, which is a jet injection type, and infiltrative anesthesia with a traditional injector, and to measure the effect of children's anxiety on the…
- Conditions
- Pain, Local Infiltration, Anesthesia, Fear
- Trial name
- NCT04682080
- Testing
- Needle-free injection
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
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