Clinical trials: Stone;Renal
Renal Stone
Percutaneous Nephrolithotomy for Treatment of Kidney Stones Greater Than 2 cm
Percutaneous nephrolithotomy (PCNL) is a minimally invasive procedure considered as the treatment of choice for the management of large-scale and fully-formed kidney stones.This procedure has a 5% risk of complications including…
- Trial name
- NCT03189264
- Testing
- percutaneous nephrolithotomy for kidney stones
- Where
- Colombia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr Carlos Hernández
Healthy Volunteers, Enteric Hyperoxaluria
Safety, Tolerability, and Pharmacodynamics of NOV-001 in Adult Subjects
The first stage of this study is a prospective, adaptive, Phase 1, first-in-human, randomized, controlled study evaluating safety, tolerability, and pharmacodynamics of NOV-001 in adult healthy volunteers.
- Trial name
- NCT04909723
- Testing
- NOV-001, NB1000S, NB2000P
- Where
- 20 sites in United States, Canada
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Novome Biotechnologies Inc
Kidney Stone
Influence of Obesity on Endogenous Oxalate Synthesis
There is increasing evidence that obesity is associated with increased urinary oxalate excretion, an important risk factor for calcium oxalate stone formation.
- Trial name
- NCT03704350
- Testing
- controlled diet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Kidney Transplantation, Urinary Calculi
Evaluation of Kidney Function by Multi-modal Magnetic Resonance Imaging and Spectroscopy
Multimodal functional magnetic resonance (MR) methods, including MR diffusion, Blood-Oxygenation Level Dependent (BOLD) imaging and MR spectroscopy may provide complementary information about the functional status of a kidney.
- Trial name
- NCT00575432
- Testing
- diffusion MRI, BOLD MRI, Clinical Outcome
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ureteroscopy
The Role of Ureteral Stenting Following Uncomplicated Ureteroscopy for Ureteral and Renal Stones: A Randomized, Controlled Trial
It is well established that uncomplicated distal ureteroscopy can be safely performed without leaving a ureteral stent. However, many urologists continue to leave ureteral stents following uncomplicated ureteroscopy, regardless…
- Trial name
- NCT03130907
- Testing
- Placement of ureteral stent
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- San Antonio Uniformed Services Health Education Consortium
Renal Stone Disease
Intrarenal Pressure Monitoring During Pediatric Percutaneous Nephrolithotomy, and Its Impact on Post Operative Infectious Complications.
Monitoring of intrarenal pressure during pediatric percutaneous nephrolithotomy and its impact on post operative infectious complications.
- Trial name
- NCT07800546
- Testing
- Intrarenal pressure
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Kidney Stone, Healthy
Oxalate and Citrate in Humans - Response to Citrate
This is a single-center study that aims to learn more about how two compounds found in food, oxalate and citrate, interact in the body and may influence a person's chances of forming kidney stones.
- Trial name
- NCT06944223
- Testing
- Kidney stone formers, Control cohort
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Kidney Stones
Donors With Nephrolithiasis at the Time of Transplant Evaluation (DONATE). Long Term Follow-up.
We believe that kidney donors with kidney stones accepted for a donation do not have an increased risk of loss of kidney function and will not be at increased risk of symptomatic kidney stone events compared to donors without a…
- Trial name
- DONATE (NCT05519150)
- Testing
- low dose radiation abdomen/pelvis CT scan (stone protocol), Blood draw, 24 hour urine collection
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Indiana University
Urinary Stone, Renal Injury
Urinary NGAL and KIM-1 After ESWL
The goal of this prospective observational study is to evaluate the effect of different time intervals between extracorporeal shock wave lithotripsy (ESWL) sessions on renal injury using urinary biomarkers in patients with…
- Trial name
- NCT07341269
- Testing
- No Interventions, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Urolithiasis
Urine and Stool Analysis in Kidney Stone Disease
The purpose of this study is to add to the investigators' quest to understanding stone disease, by evaluating the metabolites excretion in urine and its relation to microflora present in the stool.
- Trial name
- NCT01637506
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Kidney Stone Prevention
Protein Sources Urinary Stone Risk
Prior studies have shown that the source of dietary protein can have a significant impact on urinary stone risk. However, whey and plant protein isolates have not been compared.
- Trial name
- NCT05460247
- Testing
- Protein
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Kidney Stones
Stone Centre Urine and Serum Bank
Purpose: The purpose of the Stone Centre Serum and Urine Bank is to provide researchers with large numbers of serum and urine samples from kidney stone patients and controls for study of stone disease detection and treatment, and…
- Trial name
- NCT00759343
- Where
- 2 sites in Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Nephrolithiasis
Mature Vinegar Prophylaxis Against Recurrent Calcium Oxalate Nephrolithiasis
Kidney stones are one of the most common disorders of the urinary tract and cause a great deal of morbidity and economic loss. Because of the high recurrence rate, researchers are interested in finding medicinal therapies to…
- Trial name
- NCT03092908
- Testing
- mature vinegar
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stones, Ureteral Stones
The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients
To determine if emergency department patients with acute ureteral colic pain due to a ureteral stone who are treated with tamsulosin, versus placebo, will experience a shorter time to passage of their stone or resolution of their…
- Trial name
- NCT00448123
- Testing
- Tamsulosin
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Robert Swor
Kidney Stones
Extracorporeal Shock Wave Lithotriptor Indicated for Fragmenting Urinary Stones in the Kidney
A total of 20 subjects presenting with urinary stone(s) in the kidney or ureter will be treated with an extracorporeal shockwave lithotripsy device to fragment the stones. Subjects will be followed for 14 days.
- Trial name
- NCT00959153
- Testing
- LithoSpace Extracorporeal Shockwave Lithotripter
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Advance Shockwave Technology GmbH
Kidney Stone
Can Shear Wave Elastography Predict the Success of ESWL: a Prospective Study
Can Shear Wave Elastography predict the success of Shock-Wave Lithotripsy used in renal stones treatment ? A prospective study
- Trial name
- NCT05995652
- Testing
- elastography
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Abdelrahim Elsherbiny
Stone, Kidney, Ultrasound Therapy; Complications
Accuracy of Ultrasound for Detecting Residual Fragments During RIRS
The purpose of this study is to assess the accuracy of ultrasound and traditional fluoroscopy to find the residual fragments before retrograde intrarenal surgery is complete.
- Trial name
- NCT05535816
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Shockwave Therapy
Role of Urine PH in Shock Wave Lithotripsy Outcomes in Renal Stone Disease
urolethiasis (kidney stones) is common globally, with recurrence in 50% of patients. Shock Wave Lithotripsy (SWL) is a minimally invasive treatment for stones < 2 cm.
- Trial name
- PHESWL (NCT07711028)
- Testing
- Shock Wave Iithotripsy, Extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Benha University
Urolithiasis
High Supracostal Versus Subcostal Puncture in Adult PCNL
as the supra eleventh puncture PCNL is not well investigated in the literature we will conduct that randomised trial in comparison to the subcostal one
- Trial name
- NCT06350045
- Testing
- PCNL
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Assiut University
Renal Calculi
FANS VS DISS in Treatment of Renal Stone < 2cm
To compare between FANS \& DISS in : Operative time Stone free rate Complications Amount of fluid irrigation
- Trial name
- NCT07559214
- Testing
- Flexible ureteroscopy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University