Clinical trials: Stones, Kidney
Pneumothorax, Intestinal Obstruction
The Impact of Artificial Intelligence-Assisted X-ray Interpretation on Radiologists' Diagnostic Performance
This study tests whether an artificial intelligence (AI) tool helps radiologists read X-rays more accurately. Radiologists read X-rays to find diseases such as pneumonia, bone fractures, and abdominal problems.
- Conditions
- Pneumothorax, Intestinal Obstruction, Spondylolysis, Renal Calculus
- Trial name
- NCT07870928
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Southern Medical University
Nephrolithiasis, Urinary Tract Infections
A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
When patients are going to have surgery to remove large kidney stones (percutaneous nephrolithotomy [PCNL]), it is not clear whether the patients benefit from a course of prophylactic preoperative oral antibiotics; currently both…
- Trial name
- NCT02384200
- Testing
- nitrofurantoin monohydrate/macrocrystalline capsules, ampicillin, gentamicin
- Where
- 8 sites in United States, Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Kidney Calculi, Calcium Oxalate Kidney Stones
Evaluating the Vitamin K2 Status of Calcium-based Stone Formers
This is an observation, single site-study with one study visit during which all data and samples will be collected. Study participants will be asked to provide blood, urine, and fecal samples so that the investigators may study…
- Conditions
- Kidney Calculi, Calcium Oxalate Kidney Stones, Vitamin K 2, Human
- Trial name
- NCT05081960
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Stone
A Prospective Observational Comparison of SMP and ESWL for the Treatment of Renal Stones ≥20 mm in Children (IAU-04)
ESWL and PNL are the two treatment modalities for kidney stones greater than 20 mm in the pediatric population. ESWL is non-invasive, does not require anesthesia and inexpensive, but its success rate may be lower, and require…
- Trial name
- NCT04317443
- Testing
- Super-mini percutaneous nephrolithotomy (SMP), Extracorporeal Shock Wave Lithotripsy (ESWL)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The International Alliance of Urolithiasis
Urolithiasis
sipIT2: Improving Adherence to Fluid Intake Guidelines for Kidney Stone Prevention
The purpose of this study is to examine the feasibility of using sipIT tools (i.e., wrist-worn sensors, smart water bottles, mobile applications) to increase compliance with physician-recommended fluid consumption guidelines in…
- Trial name
- NCT05196113
- Testing
- sipIT
- Where
- 2 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Kidney Stone, Oxidative Stress
Lime Powder Regimen in Healthy Volunteers
The study aims to investigate the pharmacokinetic parameters and its antioxidative effects in Thai healthy men.
- Trial name
- LimePKphase1 (NCT01273025)
- Testing
- Lime powder regime
- Where
- Thailand
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Kidney Stone
Comparing Pneumatic Versus Ultra-sonic Percutaneous Nephrolithotomy in Large Kidney Stones
The purpose of this study is to determine which type of percutaneous nephrolithotomy is better in large kidney stones
- Trial name
- NCT02751281
- Testing
- Pneumatic percutaneous nephrolithotomy, Ultra-sonic percutaneous nephrolithotomy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Shockwave Therapy
Role of Urine PH in Shock Wave Lithotripsy Outcomes in Renal Stone Disease
urolethiasis (kidney stones) is common globally, with recurrence in 50% of patients. Shock Wave Lithotripsy (SWL) is a minimally invasive treatment for stones < 2 cm.
- Trial name
- PHESWL (NCT07711028)
- Testing
- Shock Wave Iithotripsy, Extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Benha University
Nephrolithiasis, Percutaneous
Comparison of Erector Spinae Plane Block and Intravenous Patient-controlled Analgesia in Percutaneous Nephrolithotomy
The primary purpose of this study was to compare the effects of erector spinal plane block (ESP) and IV patient-controlled analgesia (PCA) performed to provide analgesia in percutaneous nephrolithotomy surgeries on visual analog…
- Conditions
- Nephrolithiasis, Percutaneous, Analgesia, PCA
- Trial name
- NCT05845281
- Testing
- Bupivakain + deksametazon Adjuvant
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Kidney Stones, Urolithiasis, Hypocitraturia
Apple Cider Vinegar for the Prevention of Urinary Lithiasis (APUL)
The purpose of this study is to assess whether certain beverages can increase urinary citrate levels in healthy individuals with no history of kidney disease.
- Trial name
- APUL (NCT04073719)
- Testing
- Apple Cider Vinegar, Other Beverage
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Hyperoxaluria
Effect of Over-the-counter Dietary Supplements on Kidney Stone Risk
The purpose of this study is to ascertain whether certain supplements promote excessive urinary oxalate excretion and increase the risk for calcium oxalate kidney stones.
- Trial name
- NCT02404701
- Testing
- Aloe vera with cactus, Cranberry, Green tea extract
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Renal Stones
RIRS Versus ESWL for the Treatment of Renal Stones
To evaluate the effectiveness of RIRS (retrograde intrarenal surgery) and ESWL (extracorporeal shockwaves lithotripsy) in the treatment of renal stone ranging form 6 to 20 mm size.
- Trial name
- NCT02645058
- Testing
- RIRS, ESWL, Rigid and flexible ureteroscope
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Healthy Volunteers, Enteric Hyperoxaluria
Safety, Tolerability, and Pharmacodynamics of NOV-001 in Adult Subjects
The first stage of this study is a prospective, adaptive, Phase 1, first-in-human, randomized, controlled study evaluating safety, tolerability, and pharmacodynamics of NOV-001 in adult healthy volunteers.
- Trial name
- NCT04909723
- Testing
- NOV-001, NB1000S, NB2000P
- Where
- 20 sites in United States, Canada
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Novome Biotechnologies Inc
Kidney Stones
Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy
The investigators main hypothesis is that the stone free rate will be much higher (95%) in patients treated with PCNL than patients treated with ESWL where stone free rate is (60%) to determine which treatment is safe and prevent…
- Trial name
- NCT00873054
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Kidney Stones, Nephrolithiasis
Effect of Diet Orange Soda on Urinary Lithogenicity
Beverages containing citrate may be useful in increasing urine citrate content and urine pH. Such changes in urine chemistry could help prevent kidney stones. Diet orange soda has more citrate than other similar beverages.
- Conditions
- Kidney Stones, Nephrolithiasis, Urolithiasis
- Trial name
- NCT01330940
- Testing
- Orange soda
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA New York Harbor Healthcare System
Renal Stones, Nephrolithiasis
Efficacy of Tranexamic Acid on Blood Loss During Percutaneous Nephrolithotomy.
Efficacy of tranexamic acid on blood loss during percutaneous nephrolithotomy. a double-blind, placebo-controlled randomized clinical trial.
- Trial name
- NCT04367155
- Testing
- Tranexamic acid injection
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Kidney Stone
The Interplay Between Oxalate, Immunity and Infection
This study consists of having subjects, those with calcium oxalate kidney stones as well as healthy controls, consume low and oxalate enriched diets to investigate the role of oxalate on crystalluria (the presence of crystals in…
- Trial name
- NCT04605055
- Testing
- Low Oxalate Diet, High Oxalate Diet
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Renal Stones
Treatment of Renal Stones With Frankincense (Luban)
Frankincense, or olibanum, is the oleogum resin that is harvested from several different trees, an aromatic resin obtained from trees of the genus Boswellia.
- Trial name
- Luban (NCT03924596)
- Testing
- AKBA-Incense (3-acetyl-11-keto-ß-boswellic acid), Potassium Sodium Hydrogen Citrate
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sultan Qaboos University
Renal Cell Carcinoma (Kidney Cancer), Kidney Cancers
Targeted Abdominal CT in Conjunction With Lung Cancer Screening
Early detection through screening can improve cancer survival by identifying it when it's most treatable. The NHS now offers Lung Cancer Screening (LCS) assessments to people aged 55-74 who have ever smoked.
- Conditions
- Renal Cell Carcinoma (Kidney Cancer), Kidney Cancers, AAA - Abdominal Aortic Aneurysm, Renal Stones
- Trial name
- TACTICAL1 (NCT07171190)
- Testing
- Lung Cancer Screening Invitation Intervention, Abdominal scan intervention
- Where
- United Kingdom
- Volunteers
- 6,272 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Urologic Injuries, Disorder of Urinary Stent
Indwelling Stent Discoloration Project
The aim of this study is to identify the root cause for the significant discolouration of Boston Scientific Percuflex based stents.
- Conditions
- Urologic Injuries, Disorder of Urinary Stent, Kidney Calculi, Urinary Tract Obstruction Due to Specified Cause
- Trial name
- NCT02007980
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of British Columbia