Clinical trials: Stool Assessment
Parkinson Disease
Evaluation of the Efficacy and Safety of Fecal Microbiota Transplantation for Constipation in Parkinson's Disease
Participants will be allocated to FMT group or placebo group at a 1:1 ratio. For interventional group, patients will be given six FMT capsules twice a week for 24 weeks.
- Trial name
- NCT06388863
- Testing
- Healthy donor-derived FMT capsule
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Colorectal Cancer Screening Fecal Immunochemical Test
Multi-center Application of Quantitative FIT Technology in Colorectal Cancer Screening
In order to control the incidence of colorectal cancer, improve the level of early diagnosis and early warning the occurrence of colorectal cancer, it is very necessary for us to explore the threshold value of FIT positive…
- Trial name
- NCT04959617
- Testing
- Quantitative Fecal Immunochemical Test (qFIT)
- Where
- China
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Crohn Disease
The Intensive Post Exclusive Enteral Nutrition Study
Crohn's disease (CD) is a chronic inflammatory condition with phases where the disease is active and other, where there are no symptoms.
- Trial name
- iPENS (NCT04225689)
- Testing
- CD-TREAT diet
- Where
- 5 sites in United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Dysphagia, Fecal Incontinence
Evaluation of Potential Vitamin D Effects on Muscle: a Pilot Study
People who do not have adequate amounts of vitamin D develop weakness of leg and arm muscles. This study will determine if vitamin D supplementation benefits muscle functions important for swallowing, bladder and bowel function.
- Conditions
- Dysphagia, Fecal Incontinence, Urinary Incontinence
- Trial name
- NCT00593996
- Testing
- Ergocalciferol (vitamin D2)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Colorectal Neoplasms
Screening of Colorectal Cancer in the Public Healthcare Sector in Argentina
Introduction: Early detection of certain types of cancer significantly increases the likelihood of successful treatment and reduces mortality from these causes.
- Trial name
- NCT04293315
- Testing
- Improvement Cycles
- Where
- Argentina
- Volunteers
- 1,520 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical Effectiveness and Health Policy
Functional Constipation, Healthy
Effect of scFOS on Increase in Stool Frequency in Constipated People
The study aims to evaluate the effects of short-chain fructo-oligosaccharides on the frequency and consistency of stools in subjects with functional constipation.
- Trial name
- CONSYST (NCT03707002)
- Testing
- scFOS, Maltodextrin
- Where
- France
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Syral
Constipation
Evaluation of Acacia Gum on Microbiome and Bowel Function in Participants With Chronic Constipation
Proof of concept study to investigate the impact of a food supplement consisting of Acacia gum on changes of gut microbiota and production of short chain fatty acids.
- Trial name
- NCT04382456
- Testing
- acacia gum
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alpinia Laudanum GmbH
Colorectal Cancer (Diagnosis)
Secondary Care Colorectal Cancer Pathway Review
Bowel cancer (colorectal cancer) is the 4th most common cancer in Scotland. Approximately 4,000 cases are diagnosed annually. Cancer-related deaths in Scotland are higher than other UK nations.
- Trial name
- NCT07430527
- Testing
- Faecal Immunohistochemical test
- Where
- 2 sites in United Kingdom
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Constipation, Gastrointestinal Dysfunction
Effect of Polydextrose on Fecal Bulk and Bowel Function in Mildly Constipated Subjects
Polydextrose (PDX) (8-30g/day) has been reported to increase faecal bulk and consistency, leading to easier stool passage in healthy subjects.
- Trial name
- NCT05309837
- Testing
- Polydextrose
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Tate & Lyle
Lactose Intolerance
Effects of Lactose on Fecal Microflora
The genetics of lactase divides the population into 2 phenotypes: Those who can(LP) and those who cannot(LNP)digest lactose. This division may help modify disease risks according to geographic population distribution.
- Trial name
- ELM (NCT00599859)
- Testing
- lactose
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Inflammatory Bowel Disease, Crohn Disease
Deep Endoscopic Remission Assessed by a Surrogate Biomarker in Patients With Inflammatory Bowel Disease
We hypothesize that the number of needed endoscopic procedure performed at IBD patients (adult and children), can be reduced by using an individualized algorithm of symptoms, blood and faecal biomarkers.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT01861288
- Where
- Denmark
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
To Evaluate the Sensitivity and Specificity of a Test Kit in Hong Kong
The Diagnostic Accuracy of Using Faecal-DNA Test (COLOSAFE) for Colorectal Cancer Screening
To evaluate the sensitivity and specificity of the test kit "COLOSAFE' in Hong Kong
- Trial name
- NCT04030637
- Where
- Hong Kong
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Frail Elderly, Clostridioides Difficile
Clostridioides Difficile and Frailty
CDI is a major cause of antibiotics-associated diarrhoea. More than half of the patients affected are 70 years or older and frail. Mortality among older patients with CDI is high.
- Conditions
- Frail Elderly, Clostridioides Difficile, Geriatric Assessment, Faecal Microbiota Transplantation
- Trial name
- CLODIFRAIL (NCT05447533)
- Testing
- Comprehensive geriatric assessment (CGA), Continued geriatric care, Faecal microbiota transplantation (FMT)
- Where
- Denmark
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Infant
A Real-world Evidence (RWE) Study to Assess Infant Stool Consistency in France
The objective of this study is to investigate the influence of various factors (e.g. diet) on the stool consistency of infants in France.
- Trial name
- Popodata (NCT07745413)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Stool Assessment
Amsterdam Stool Scale: Usefulness in Clinical Setting
The aim of this study is to assess interobserver and intraobserver variability of the Amsterdam Stool Scale in clinical practice.
- Trial name
- NCT02252718
- Testing
- Stool Assessment
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Hepatic Encephalopathy, Fecal Microbiota Transplantation
Evaluation of the Outcome of Fecal Microbiota Transplantation
This study is a randomized, placebo-controlled, exploratory phase II clinical trial led by Professor Han Gyeong-ho from the Digestive Disease Hospital of Xi'an International Medical Center.
- Conditions
- Hepatic Encephalopathy, Fecal Microbiota Transplantation, TIPS
- Trial name
- NCT07454408
- Testing
- Fecal Microbiota Transplantation, Rifaximin、Lactulose
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Colorectal Cancer
An Evaluation of a Multi-target Stool DNA (Mt-sDNA) Test, Cologuard, for CRC Screening in Individuals Aged 45-49 and at Average Risk for Development of Colorectal Cancer: Act Now
The primary objective is to confirm the specificity of a multi-target stool DNA test (mt-sDNA), Cologuard, in an average risk population, ages 45-49.
- Trial name
- NCT03728348
- Testing
- mt-sDNA screening test, Colonoscopy
- Where
- 39 sites in United States
- Volunteers
- 983 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Fecal Incontinence
Safety, Tolerability, Pharmacodynamic and Pharmacokinetics of a Single Rectal Application of 10 mg NRL001 in Elderly Subjects
A total of 26 healthy elderly male and female subjects will receive both 10 mg NRL001 in a 2 g rectal suppository and placebo in this double-blind, cross-over study.
- Trial name
- NCT01099683
- Testing
- NRL001
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Norgine
Obesity
Energy Metabolism and Nutrient Absorption in Lean and Obese Individuals
This study will examine whether there are differences in energy (calories) losses in stool and urine between lean and obese people.
- Trial name
- NCT00414063
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Gastrointestinal Health
Effects of Dietary Fiber on Gastrointestinal Function
The purpose of the study will be to assess the gastrointestinal effects of a dietary fiber in healthy, adult volunteers.
- Trial name
- NCT01495182
- Testing
- Dietary fiber
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ingredion Incorporated