Clinical trials: Strain
Shigella Infection
Healthy Adult Volunteer Study for Two Doses of a Shigella Vaccine
The purpose of this study is to assess the immune response produced by two doses of SC599 vaccine compared to placebo.
- Trial name
- NCT00210288
- Testing
- SC599
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Cardiomyopathies
International Study of Artificial Intelligence-based Diagnosis of Cardiomyopathy Using Cardiac MRI (AID-MRI)
The goal of this observational study is to test the accuracy of computer (machine learning-based) algorithms to diagnosis heart diseases and predict if and when heart complications will occur.
- Trial name
- AID-MRI (NCT05793840)
- Where
- 2 sites in Canada
- Volunteers
- 1,100 people
- Sponsor
- University of Calgary
Tissue Expander Disorder, Stress Strain Curve
Use of a Novel Device for Stretch Relaxation During Mohs Surgery
Closure of cutaneous defects is associated with many common and serious problems. For example, Mohs surgery involves the removal of skin and other soft tissues that have been proven to be infiltrated with cancer.
- Conditions
- Tissue Expander Disorder, Stress Strain Curve, Tissue Expansion, Mohs Surgery
- Trial name
- NCT03586960
- Testing
- Peak Force Measurement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Silver Falls Dermatology
Cholera
Safety and Immunogenicity of Locally Manufactured New (HL-OCV) Oral Cholera Vaccine
Cholera, a rapidly dehydrating watery diarrheal disease transmitted through water or food contaminated with the bacterium, Vibrio cholerae, is a major cause of morbidity and mortality in low income countries like Bangladesh.
- Trial name
- NCT02823899
- Testing
- HL-OCV, Shanchol
- Where
- Bangladesh
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Recurrent Cystitis
Colipral® (Probiotic Strain Escherichia Coli 5C (ECP24®)) for Prevention of Recurrent Cystitis in Menopausal Women
Recurrent cystitis is a common condition in menopausal women and is associated with impaired quality of life and increased antibiotic use.
- Trial name
- NCT07676604
- Testing
- Colipral®
- Volunteers
- 134 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Cognitive Deficit in Attention, Musculoskeletal Strain
Effect of Surgeon Warm-up and Mental Visualisation During Robot-assisted Laparoscopic Surgery
Study Design - A Counterbalanced Study Aims - To determine the effect of a) warm-up exercises and b) mental visualisation on the musculoskeletal demands and cognitive demands respectively during robot-assisted laparoscopic…
- Conditions
- Cognitive Deficit in Attention, Musculoskeletal Strain, Fatigue, Surgery
- Trial name
- MURALS2 (NCT05884385)
- Testing
- Simulated exercises, Mental Visualisation
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Fluid Responsivness, Right Ventricle
Evaluation of the Association Between Right Atrial Reservoir Strain Variation and Fluid Responsiveness in Patients With Septic Shock
Evaluating preload dependence is crucial for managing fluid administration in septic shock patients. To avoid unnecessary fluid administration, it's recommended to use dynamic tests like the passive leg raising (PLR) maneuver or…
- Trial name
- RAS-FR (NCT06492044)
- Testing
- Transthoracic echocardiography (TTE)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
ST Elevation Myocardial Infarction, Remodeling, Left Ventricle
Predictors of Adverse Left Ventricular Remodeling and Final Infarct Size After Primary Percutaneous Coronary Intervention for ST Elevation Myocardial Infarction: A Strain Analysis Study Using Echocardiography and Feature Tracking Cardiac Magnetic Resonance
ST-segment elevation myocardial infarction (STEMI) is one of the most important causes of death and disability around the world.
- Trial name
- NCT04773652
- Testing
- speckle tracking echo
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Crohn's Disease
Effect of the Consumption of a Probiotic Strain on the Prevention of Post-operative Recurrence in Crohn's Disease
A double-blind, multicentre, stratified by centre, randomised, parallel study with two groups of adult patients operated on for Crohn's disease, to determine if oral ingestion of probiotics could prevent the appearance of Crohn's…
- Trial name
- NCT01698970
- Testing
- 1-Freeze-dried Probiotics provided in capsule (150 mg) containing 1,0x10E10 colony forming unit per capsule (test), 2- excipients (150 mg) in capsule (control)
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Danone Global Research & Innovation Center
Sarcopenia, Inflammation
Effect of Fermented Milk Containing Lactobacillus Casei Strain Shirota in Sarcopenia Elderly
Sarcopenia, which refers to the progressive loss of skeletal muscle mass and strength, shares many characteristics with other disease states typically associated with risks of falling and fracture, including osteoporosis…
- Conditions
- Sarcopenia, Inflammation, Aging
- Trial name
- NCT04985877
- Testing
- Yakult 300 LIGHT Fermented Milk
- Where
- 3 sites in Taiwan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Aging, Heat Stress
Establishing Evidence-based Indoor Temperature Thresholds to Protect Health
An individual's ability to adequately cope with short- or long-term increases in ambient temperature is critical for maintaining health and wellbeing.
- Conditions
- Aging, Heat Stress, Physiological Stress
- Trial name
- HW2 (NCT04348630)
- Testing
- Simulated heatwave exposure
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Computer Vision Syndrome, Asthenopia
Yogic Eye Exercises for Computer Vision Syndrome in Female Design Students
Computer vision syndrome (CVS) is a cluster of eye and musculoskeletal complaints - dryness, redness, blurred vision, foreign body sensation, excessive tearing, and neck, shoulder or back pain - that arises from prolonged work at…
- Conditions
- Computer Vision Syndrome, Asthenopia, Eye Strain, Dry Eye
- Trial name
- NCT07816419
- Testing
- Yogic eye exercise programme
- Where
- Saudi Arabia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- King Saud University
Human Metapneumovirus
Safety Study of a Human Metapneumovirus Challenge Virus in Healthy Adults
Human metapneumovirus (HMPV) is a virus that can cause respiratory illness. In older adults, those with asthma, infants, and children, illness can be severe, but in healthy adults the virus frequently causes no symptoms.
- Trial name
- NCT01109329
- Testing
- HMPV challenge virus
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Obesity, Abdominal Obesity
Study of Safety and Efficacy of a Probiotic and Postbiotic in Overweight Individuals
Investigate the effect of a probiotic (live bacteria) and postbiotic (heat-treated bacteria) strains in overweight individuals.
- Trial name
- KOBI (NCT05428137)
- Testing
- Probiotic, Postbiotic
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Premature Ventricular Complexes, Ventricular Arrhythmias
Impact of Catheter Ablation of Frequent Premature Ventricular Complexes in Treating Subtle Left Cardiomyopathy
Throughout the past decade, there were no straightforward recommendations regarding the management of asymptomatic high-burden Premature ventricular complexes (PVCs) in structurally normal heart extending from the European…
- Trial name
- NCT06864429
- Testing
- Radiofrequency catheter ablation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Heart Failure With Reduced Ejection Fraction (HFrEF)
Correlation of Typical LBBB Mechanical Activation Pattern by 2D Strain Echocardiography With Acute GWE Improvement in Patients Receiving LBBp or Conventional BiVp for Cardiac Resynchronization Therapy (Echo LBBp)
The present study is a multicenter interventional non randomised study in patients requiring an implantable device for cardiac resynchronization therapy.
- Trial name
- ECHO-LBBp (NCT06689111)
- Testing
- Left bundle branch pacing lead, CRT with the standard method through cs
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University Hospital of Patras
Ankle Injuries, Ankle Fractures
Deltoid Ligament Arthroscopic Repair in Ankle Fractures: Case Series
To demonstrate the functional results of patients with ankle fractures operated with arthroscopic deltoid repair.
- Conditions
- Ankle Injuries, Ankle Fractures, Deltoid Ligament; Sprain (Strain) (Ankle), Ligament Rupture
- Trial name
- NCT04473638
- Testing
- Arthroscopic Deltoid Repair
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of São Paulo
Musculoskeletal Pain, Musculoskeletal Injury
Monitoring and Evaluation of Posture in Office Workstations With Artificial Intelligence
Office workers spend 11.6 hours per day in sedentary activities during the day, leading to increased health risks. Although there is literature on prevalence of musculoskeletal disorders and work station modification for office…
- Conditions
- Musculoskeletal Pain, Musculoskeletal Injury, Musculoskeletal Strain
- Trial name
- NCT04122326
- Testing
- Workstation Modification
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Sports Nutrition, Biochemical Markers
Effect of a Short-term Multi-strain Probiotic Supplementation in Endurance Athletes
The aim of this project is to evaluate and identify the effect of a short-term 2-week multi-strain probiotic (MPRO) supplementation on the exercise-associated gastrointestinal (GI) symptoms and perturbations in high level female…
- Conditions
- Sports Nutrition, Biochemical Markers, Exercise Performance, Aerobic Capacity
- Trial name
- NCT07252778
- Testing
- MPRO supplementation
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Krzysztof Durkalec-Michalski
Heart Failure
Deep Learning-Based Automated Pressure-Strain Loop Analysis
Noninvasive left ventricular pressure-strain loop analysis estimates myocardial work from longitudinal strain, brachial systolic blood pressure, and cardiac valve-event timing.
- Trial name
- NCT07850726
- Testing
- Sustained Isometric Handgrip Exercise, Semi-Supine Bicycle Exercise
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology