Clinical trials: Strain
Attention Deficit and Hyperactivity Disorders
Multi-strain Probiotics for ADHD
Probiotics are widely used as supplement for various neurodevelopmental disorders. The mechanism of their therapeutic potential lies in the "gut-brain axis", a two-way communication pathway through the neuroendocrine system.
- Trial name
- NCT06226584
- Testing
- multiple-strain probiotics
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Tsyr-Huey Mental Hospital
Aortic Stenosis, Cardiac Death
Endothelial Progenitors in Aortic Stenosis: Association With Aortic Stenosis Progression and Severity
There is a correlation between endothelial progenitor cells (stem cells) and stenosis of the aortic valve.
- Trial name
- NCT02060071
- Testing
- Blood test
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
COVID-19
Immunogenicity and Safety Study of Booster Vaccine With the COVID-19 Vaccine (Vero Cell), Inactivated, Omicron Strain
This is a randomized, open-labeled, Phase IIb clinical trial.The purpose of this study is to evaluate the immunogenicity and safety of the booster vaccine of using one or two doses of COVID-19 Vaccine (Vero Cell), Inactivated…
- Trial name
- NCT05411471
- Testing
- COVID-19 Vaccine (Vero Cell), Inactivated, Omicron Strain
- Where
- China
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech (Hong Kong) Limited
ARDS, Right Ventricle
Speckle Tracking and Inhaled Nitric Oxide in Acute Respiratory Distress Syndrome
Acute cor pulmonale is one of deadly complications of mechanically ventilated acute respiratory distress syndrome (ARDS), which can lead to right ventricular dysfunction and worsen the hemodynamics of the patient.
- Trial name
- NOSPECKLE (NCT05104606)
- Testing
- TEE, TTE
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Sprain and Strain of Ankle
Effect of Kinesiotaping on Ankle Stability
Ankles sprains are the most popular injuries in basketball players. They are traumatic injuries, which happen most of the time in specific situations, like landing on another player's foot, or during changes of direction.
- Trial name
- NCT02115217
- Testing
- Leukotape K
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Clinique Romande de Readaptation
Musculoskeletal Injury, Musculoskeletal Strain
Multi-axis Assessment of Injured Workers
The percentage of loss time claims receiving Loss of Earnings benefits at 3 months has continued to rise amongst injured workers in Ontario despite the Workplace Safety and Insurance Board (WSIB) approach of "Better at Work".
- Conditions
- Musculoskeletal Injury, Musculoskeletal Strain, Low Back Pain, Neck Pain
- Trial name
- NCT06016647
- Testing
- Musculoskeletal-specific WSIB programs of care
- Where
- Canada
- Volunteers
- 350 people
- Sponsor
- Dave Walton
Vaginitis, Dysbiosis
Oral Multi-Strain Lactobacillus Probiotic for Women With Vaginal Dysbiosis
Many women have an imbalance in their vaginal bacteria that can cause discomfort, irritation, and repeat infections. In a healthy vagina, helpful Lactobacillus bacteria are the main group of microbes.
- Conditions
- Vaginitis, Dysbiosis, Vaginal Diseases
- Trial name
- NCT07882134
- Testing
- Low-dose multi-strain Lactobacillus capsule, High-dose capsule
- Where
- South Korea
- Volunteers
- 119 people
- Sponsor
- Soon Chun Hyang University
Heart Failure, Heart Failure With Preserved Ejection Fraction
Follow Up of acuTe Heart failUre: a pRospective Echocardiographic and Clinical Study (FUTURE)
Acute heart failure (AHF) is defined as rapid onset or rapid worsening of typical signs and symptoms of heart failure (HF) according to the 2016 European Society of Cardiology Guidelines.
- Conditions
- Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction, Heart Failure With Reduced Ejection Fraction
- Trial name
- FUTURE-HIT (NCT05204238)
- Testing
- Transthoracic Echocardiography
- Where
- 31 sites in Australia, Belgium and 10 more
- Volunteers
- 998 people
- Sponsor
- University of Siena
Probiotics
The Effect of a Multi-strain Probiotic on Acclimatization to High Altitude
The goal of this study is to learn if the probiotic SLAB51 (Sivomixx800®) works to enhance acclimatization to high altitude in humans.
- Trial name
- NCT06552806
- Testing
- SLAB51
- Where
- 2 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Seasonal Influenza Vaccine
Safety and Immunogenicity of Trivalent Subunit Influenza Vaccine Produced in Mammalian Cell Culture Using the Strain Composition 2007/2008
Annual trial for registration of sub-unit influenza vaccine produced in mammalian cell culture, using the strain composition 2007/2008, when administered to adult and elderly subjects
- Trial name
- NCT00511914
- Testing
- cTIV
- Where
- 2 sites in Germany
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Influenza
Safety and Immunogenicity of Two Doses of a Tetravalent Influenza Vaccine in Adults Aged 18 Years and Above
Evaluate the immune response and reactogenicity of H5N1 vaccination in adults aged 18 years and above (as part of a tetravalent vaccine)
- Trial name
- NCT00620815
- Testing
- Pandemic influenza vaccine + seasonal influenza vaccine /pandemic influenza vaccine, Pandemic influenza vaccine + seasonal influenza vaccine / pandemic influenza vaccine
- Where
- 2 sites in Germany
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Influenza
Tolerability and Immunogenicity Study of Fluval AB Influenza Vaccine in Adults and Elderly Persons
The purpose of this study is to determine the immunogenicity and tolerability of Fluval AB trivalent influenza vaccine in adults and elderly people.
- Trial name
- NCT01404182
- Testing
- Vaccination with Fluval AB influenza vaccine
- Where
- 2 sites in Hungary
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Fluart Innovative Vaccine Ltd, Hungary
Sciatic Leg Pain, Hamstring Muscle Tightness
Acute Effects of Neurodynamics on Strength and Endurance in Athletes
This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population.
- Conditions
- Sciatic Leg Pain, Hamstring Muscle Tightness, Hamstring Muscle Strain, Hamstring Muscle Strength
- Trial name
- NCT07721220
- Testing
- Sciatic Slider, Sciatic Tensioner, Mechanically loaded neurodynamic sciatic floss
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- High Point University
Atrial Function
Normal Values for Myocardial Left Atrial Strain
Transversal retrospective and unicentric study. The investigators sought to determine the normal values for two-dimensional myocardial left atrial strain for the cardiology ultrasound system available in their centre (Philips…
- Trial name
- NCT03874624
- Testing
- two-dimensional speckle tracking
- Where
- Spain
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Mechanical Ventilation Complication, Ventilator-Induced Lung Injury
A New Ultrasonographic Tool to Assess Pulmonary Strain in the ICU
The primary objective of the study is to create a small dataset of regional pulmonary strain values in patients suffering from pulmonary diseases under mechanical ventilation in an intensive care setting.
- Trial name
- NCT03405779
- Testing
- Lung ultrasonography
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Poliomyelitis
Studies of the Safety and Immunogenicity of a Sabin Inactivated Poliovirus Vaccine
The purpose of this study is to evaluate the safety of sIPVs of different dosages in adults, children and infants in a phase I open-label study, and then assess its immunogenicity and safety in healthy infants between 60 and 90…
- Trial name
- NCT02985320
- Testing
- Single-dose regimen of high dosage investigational sIPV, Single-dose regimen of medium dosage investigational sIPV, Three-dose regimen of high dosage investigational sIPV
- Where
- China
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Heat Stress, Physiological Stress
Efficacy of Electric Fans in Children During Heat Waves
Extreme heat exposure is an escalating global public health concern, with climate change driving increases in the frequency, duration, and intensity of heat events.
- Conditions
- Heat Stress, Physiological Stress, Child Development
- Trial name
- NCT07864103
- Testing
- Simulated exposure to indoor overheating without fans, Simulated exposure to indoor overheating with fans
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Low Back Pain
Evaluating Pain and Functional Outcomes of Active Release Technique Versus Strain-counter- Stain in Chronic Low Back Pain
clinical trial aims to compare the effects of Active Release Technique (ART) and Strain-Counter-Strain (SCS) on pain reduction and functional improvement in male patients aged 30-45 years with chronic low back pain (CLBP)…
- Trial name
- NCT07418346
- Testing
- Strain Counter Strain, Active Release Technique
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ibadat International University, Islamabad
Office Worker, Myofascial Pain Syndrome (Upper Trapezius)
Predictors of Pressure Pain Thresholds
Objective: This cross-sectional study aimed to determine whether office-related strain risk, head and neck working posture, and weekly screen time predict the mean pressure pain threshold (PPT) at latent trigger points (LTrPs) in…
- Conditions
- Office Worker, Myofascial Pain Syndrome (Upper Trapezius), Pain Threshold, Trigger Points, Myofascial
- Trial name
- NCT07874230
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
GERD
to Assess the Efficacy and Safety of the Probiotic E. Coli Strain M17 on Patients With GERD
The study is an Open Label, Prospective, Non Comparative, Pilot, clinical trial design. Patients with inadequate relief in GI symptoms associated with GERD despite PPI treatment will be screened and those who meet the inclusion…
- Trial name
- NCT00324532
- Testing
- ProBactrix
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- BioBalance Corporation