Clinical trials: Stratification
Liver Transplantation, Carbapenem-Resistant Enterobacteriaceae Colonization
Impact of a Risk Stratification Tool on the Outcome of Liver Transplant Recipients Colonized With Carbapenem Resistant Enterobacteriaceae: an Observational Study
Although CRE infection after OLT have a dramatic impact on patient survival and several implementations have been proposed (i.e.
- Trial name
- NCT05594901
- Testing
- Application of a prognostic score
- Where
- 6 sites in Brazil, Italy and 1 more
- Volunteers
- 240 people
- Sponsor
- University of Bologna
Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury
Trajectory-Based Phenotyping After Coronary Artery Bypass Surgery
Coronary artery bypass grafting is a commonly performed heart surgery, but patients may have different risks for postoperative complications even when their preoperative risk scores are similar.
- Conditions
- Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury, Postoperative Complications, Risk Stratification
- Trial name
- NCT07598682
- Testing
- Early Postoperative Phenotype Classification
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Bursa Sevket Yilmaz Training and Research Hospital
Risk Stratification, Perioperative Medicine
Improving the Accuracy of Revised Cardiac Risk Index With HbA1C:Hemoglobin Ratio (HH Ratio)
Retrospective observational study on the effects of altering components of RCRI to improve the predictive capacity.
- Trial name
- NCT05066386
- Testing
- Modified RCRI risk stratification
- Volunteers
- 20,099 people
- Sponsor
- Singapore General Hospital
Colorectal Cancer
Prognosis Stratification for pT4bN0M0 Colorectal Cancer Following Multivisceral Resection
The purpose of this study was to identify the prognostic factors of affecting pT4bN0M0 colorectal cancer patients, so as to better stratify the prognostic differences among patients with the same stage.
- Trial name
- NCT06115837
- Testing
- multivisceral resection
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension
Pulmonary Embolism Registry From Short-Term Emergency to Long-Term Follow-Up and Surveillance
PERSEUS is an academic, investigator-initiated, multicenter observational registry of adults with acute pulmonary embolism (PE), promoted by Azienda Ospedaliero-Universitaria Careggi (Florence, Italy).
- Conditions
- Venous Thromboembolism (VTE), Chronic Thromboembolic Pulmonary Hypertension, Right Ventricular Dysfunction, Pulmonary Embolism (PE)
- Trial name
- PERSEUS (NCT07855679)
- Testing
- Routine clinical care (no study intervention)
- Where
- 16 sites in Italy, Poland and 1 more
- Volunteers
- 5,000 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Toxic Encephalopathy, Diquat Poisoning
Risk Stratification and Heterogeneity for Organ Damage in Acute Diquat Poisoning
This ambispective cohort study aims to characterize the relationship between plasma diquat concentrations and organ damage risk.
- Trial name
- NCT06798142
- Testing
- extracorporeal treatment
- Where
- China
- Volunteers
- 193 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Esophageal Neoplasms
Innovative MRI Techniques to Improve Treatment Stratification of Patients With Esophageal Cancer
The current standard treatment of resectable esophageal cancer consists of neoadjuvant chemoradiation followed by resection. However, some patients develop recurrent disease despite chemoradiation and additional (systemic)…
- Trial name
- IMPROVE (NCT02253602)
- Testing
- Ferumoxytol
- Where
- Netherlands
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Back Pain
Matching Appropriate Treatments to Consumers' Healthcare Needs, MATCH
Back pain is one of the most common, controversial and costly problems in healthcare. Despite numerous studies, care for back pain has deteriorated over time and become much more expensive.
- Trial name
- MATCH (NCT02286141)
- Where
- United States
- Volunteers
- 1,760 people
- Sponsor
- Kaiser Permanente
Covid19
Role of Hematological Parameters in the Stratification of COVID-19 Disease Severity
The hemostatic abnormalities in COVID-19 are related with disease progression, severity and mortality. The Objective of our study is to evaluate the role of hematological parameters in determination of COVID-19 disease severity.
- Trial name
- NCT04670328
- Testing
- not required
- Where
- Pakistan
- Volunteers
- 101 people
- Sponsor
- FMH College of Medicine and Dentistry
Cardiomyopathies, Primary, Arrhythmia
An Arrhythmia Risk Stratification and Genetic Trial
The prospective EUTrigTreat multi-center study is an observational, advanced diagnostics and genetic risk stratification trial in patients with standard indications for ICD treatment, with and without myocardial infarction in…
- Conditions
- Cardiomyopathies, Primary, Arrhythmia, Sudden Cardiac Death, Calcium Metabolism Disorders
- Trial name
- EUTrigTreat (NCT01209494)
- Where
- 4 sites in Belgium, Germany and 2 more
- Volunteers
- 672 people
- Sponsor
- University Medical Center Goettingen
Post Operative Care After Cardiac Surgery With Cardio Pulmonary Bypass
Bio Impedance Electrical Analysis to Predict Outcome After Cardiac Surgery
Phase angle determined by bioelectrical impedance analysis is a strong prognostic factor in several medical areas as clinical nutrition, nephrology, infectious disease, oncology.
- Trial name
- BiPOCS (NCT05229159)
- Testing
- Bioelectrical impedance analysis
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Hospices Civils de Lyon
Thyroid Nodule
The Diagnostic Value of Shear Wave Elastography
Background: The main goal when diagnosing thyroid nodules, is to differentiate the few malignant from the overwhelming background of benign nodules.
- Trial name
- NCT02150772
- Testing
- Shear Wave Elastography (SWE)
- Where
- Denmark
- Volunteers
- 308 people
- Sponsor
- University of Aarhus
Esophageal Cancer
Integrating Multimodal AI to Predict Treatment Response and Refine Risk Stratification in Esophageal Cancer （Radiogenomics-Esophagus）
This AI-driven model leverages multimodal data-such as radiomics, pathomics, genomics, and broader multi-omics profiles-to capture complementary aspects of tumor biology and predict treatment response and prognosis.
- Trial name
- NCT07354295
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Shu Peng
Malaria,Falciparum, Malaria in Pregnancy
Plasmodium Falciparum Genomic Intelligence in Mozambique
Mozambique is among the ten countries with the highest burden of malaria worldwide, with an estimated 9.3 million cases in 2018, and constitutes a core target for the World Health Organization (WHO) and the Roll Back Malaria…
- Conditions
- Malaria,Falciparum, Malaria in Pregnancy, Malaria
- Trial name
- GenMoz (NCT05306067)
- Testing
- LDH-based malaria rapid diagnostic test, Malaria rapid diagnostic test
- Where
- Mozambique
- Volunteers
- 21,848 people, healthy volunteers welcome
- Sponsor
- Centro de Investigacao em Saude de Manhica
Non-Alcoholic Fatty Liver Disease, Steatosis of Liver
Improving Diagnostic Safety Through STeatosis Identification, Risk Stratification, and Referral in the ED
Hepatic steatosis is a common radiographic "incidental finding" that is overlooked and underreported to patients. The investigators developed a clinical decision support system using machine learning and natural language…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Steatosis of Liver, Metabolic Dysfunction-Associated Steatotic Liver Disease
- Trial name
- STIRRED (NCT06944353)
- Testing
- STIRRED
- Where
- United States
- Volunteers
- 4,704 people
- Sponsor
- Northwestern University
Intrahepatic Cholangiocarcinoma (Icc)
Liquid Biopsy Using Exosomal miRNA Enables Risk Stratification of Potential Metastasis in Patients With Intrahepatic Cholangiocarcinoma.
Occult metastasis at the time of surgery is a major driver of poor outcomes in intrahepatic cholangiocarcinoma (ICC), yet reliable preoperative biomarkers to identify such patients are lacking.
- Trial name
- EXOMIC (NCT07224737)
- Testing
- EXOMIC small RNA sequencing, EXOMIC assay (qRT-PCR validation)
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- City of Hope Medical Center
Brain and Central Nervous System Tumors
Radiation Therapy or Temozolomide in Treating Patients With Gliomas
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them…
- Trial name
- NCT00182819
- Testing
- temozolomide, radiation therapy
- Where
- 89 sites in Australia, Austria and 17 more
- Volunteers
- 709 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Wolff-Parkinson-White Syndrome, Sudden Cardiac Death
Stress ECG Test for the Evaluation of the Risk of Sudden Cardiac Death in a Paediatric Cohort With WPW Pattern
Patients with preexcitation are at risk for sudden cardiac death. The pathogenesis is a rapid antegrade conduction of atrial fibrillation over the accessory pathway to the ventricle resulting in ventricular fibrillation.
- Conditions
- Wolff-Parkinson-White Syndrome, Sudden Cardiac Death, Risk Stratification
- Trial name
- NCT03207373
- Testing
- Stress test (ECG)
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- Christian Balmer
Orbital Neoplasms
Risk Stratification of Orbital Tumors Based on MRl and Artificial Intelligence
Orbital tumors can be categorized into benign and malignant tumors, and there are significant variations in their biological behavior, treatment, and prognosis.
- Trial name
- NCT06336499
- Testing
- Multi-parametric MRI and image analysis by deep learning or machine learning algorithms
- Volunteers
- 600 people
- Sponsor
- Beijing Tongren Hospital
Covid19
COVID19 Severity Prediction and Health Services Research Evaluation
1. Objectives: 1.-To create risk stratification scales of poor evolution in patients infected by SARS-CoV-2. 2.-Evaluate the accessibility and equity that these patients have had in the different care processes, diagnostic and…
- Trial name
- NCT04463706
- Testing
- Predictors adverse evolution, Predictors of health care provide
- Where
- Spain
- Volunteers
- 380,000 people
- Sponsor
- Hospital Galdakao-Usansolo