Clinical trials: Streamline or Workflow, Resulting in Reduced or Time
Blood Transfusion, Cardiac Surgery
Red Cell Storage Duration and Outcomes in Cardiac Surgery
The purpose of this study is to determine whether length of storage of RBC is related to postoperative morbid outcomes in patients undergoing cardiac surgery.
- Trial name
- NCT00458783
- Testing
- Prolonged RBC storage, Short RBC storage
- Where
- United States
- Volunteers
- 3,942 people
- Sponsor
- The Cleveland Clinic
Tuberculosis
Safety and Pharmacokinetics (PK) in Multidrug-Resistant (MDR) Refractive Tuberculosis
The purpose of this study is: To evaluate the safety and tolerability of orally administered OPC-67683 when administered two times daily to MDR tuberculosis (TB) participants refractory to treatment with an optimized background…
- Trial name
- NCT01131351
- Testing
- Delamanid, Optimized Background Regimen (OBR)
- Where
- 3 sites in Latvia, Lithuania
- Volunteers
- 10 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Labor Stage, Second
Using a Mirror in the Second Stage of Labor: Effects on Duration and Birth Experience
This study aims to investigate the impact of using a labor mirror during the second stage of labor on both the duration of labor and the mother's overall experience.
- Trial name
- NCT06648161
- Testing
- Labor Mirror
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Endometrial Clear Cell Adenocarcinoma, Endometrial Mixed Adenocarcinoma
PET/CT and Lymph Node Mapping in Finding Lymph Node Metastasis in Patients With High-Risk Endometrial Cancer
This clinical trial studies positron emission tomography (PET)/computed tomography (CT) and lymph node mapping in finding lymph node metastasis in patients with endometrial cancer that is at high risk of spreading.
- Conditions
- Endometrial Clear Cell Adenocarcinoma, Endometrial Mixed Adenocarcinoma, Endometrial Serous Adenocarcinoma, Grade 3 Endometrial Endometrioid Adenocarcinoma
- Trial name
- NCT01737619
- Testing
- Computed Tomography, Indocyanine Green Solution, Laboratory Biomarker Analysis
- Where
- 7 sites in United States
- Volunteers
- 101 people
- Sponsor
- M.D. Anderson Cancer Center
Obesity, Childhood
Addressing Health Disparities in Childhood Obesity, One Summer at a Time
Almost 50% of Native American and Hispanic children are overweight or obese by the 5th grade. Research has demonstrated that the 'obesity gap' facing minority students is largely due to summer weight gain.
- Trial name
- NCT03595332
- Testing
- Summer activity program
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
HIV/AIDS, Adherence
Monitoring Pre-exposure Prophylaxis for Young Adult Women
Next generation real-time monitoring for PrEP adherence in young Kenyan women
- Trial name
- MPYA (NCT02915367)
- Testing
- SMS Reminders
- Where
- 2 sites in Kenya
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Sedentary Behavior, Screen Time
StandUPTV: Reducing Sedentary Screen Time in Adults
The goal of this study is to develop an optimized intervention for reducing leisure sedentary screen time (SST) in middle-aged adults with overweight or obesity.
- Conditions
- Sedentary Behavior, Screen Time, Physical Activity, Sleep
- Trial name
- StandUPTV (NCT04464993)
- Testing
- Device-based feedback, self-monitoring, and education: CORE, Sedentary Screen Time lockout: LOCKOUT, Context-based prompts: TEXT
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Insomnia, Migraine
Treatment of Insomnia in Migraineurs
It is hypothesized that treating insomnia in migraineurs, many of whom also have tension headaches, prolongs total sleep time to the extent that it decreases overall headache frequency.
- Trial name
- NCT00812214
- Testing
- eszopiclone
- Volunteers
- 113 people
- Sponsor
- MedVadis Research Corporation
Pain
Intravenous Dexamethasone to Increase the Analgesic Duration of Interscalene Block
Interscalene brachial plexus block provides excellent but time limited analgesia. Intravenous dexamethasone increases the analgesic duration of a single-shot interscalene block with ropivacaine for shoulder arthroscopic surgery.
- Trial name
- NCT02412657
- Testing
- Dexamethasone, Normal Saline
- Where
- 3 sites in Canada
- Volunteers
- 75 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Tinnitus
Use of Modafinil in the Treatment of Tinnitus
A study on the effects of the FDA approved drug Modafinil upon attention problems associated with tinnitus. This is considered to be a safe drug with few side effects.
- Trial name
- NCT00591019
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Labor Pain
Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women
This study aims to evaluate the effect of meperidine on the length of active phase of labor in nulliparous or multiparous women, who will be randomized into two (control and study) groups.
- Trial name
- NCT01555671
- Testing
- Meperidine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Placental Expulsion Time
Influence of Acupuncture in the Placental Expulsion Time
In this study, a single blind randomized trial is carried out in order to compare placental detachment times when Ren Mai 6 is stimulated and when a different placebo point is used.
- Trial name
- NCT02000752
- Testing
- Acupuncture
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias
Elective Surgical Patients
Comparison of Glottic Views and Intubation Times in the Supine and 25 Degree Back-up Positions
Our hypothesis is that the view of the glottis may be improved by putting all patients requiring intubation in the ramped or back up position while maintaining the classic sniffing position.
- Trial name
- NCT02934347
- Testing
- 25 degree back-up position
- Volunteers
- 781 people
- Sponsor
- Betsi Cadwaladr University Health Board
End-Stage Renal Disease, Type 2 Diabetes
Study to Determine the Efficacy of Real-time CGM in Preventing Hypoglycemia Among Insulin-treated Patients With DM2 on Hemodialysis, Compared to Standard of Care (POC BG)
The study is conducted to assess the efficacy of real-time CGM data in preventing hypoglycemia in patients with type 2 diabetes and end-stage kidney disease (ESKD), treated with insulin therapy and receiving hemodialysis.
- Trial name
- NCT04473430
- Testing
- Dexcom Real-time G6 Continuous Glucose Monitoring System (CGM), POC Glucose Testing
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Emory University
Cesarean Section
Comparison Study of Wound Closure at Time of Cesarean Delivery: Dermabond Glue Versus Surgical Staples
Women who have a cesarean delivery have a surgical incision on their abdomen (belly). The usual way to close this opening is with metal surgical staples.
- Trial name
- NCT00524511
- Testing
- Surgical skin staples, Dermabond
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Massachusetts, Worcester
Heart Failure
Sensor-controlled Digital Game for Heart Failure Self-management
This study evaluates a sensor-controlled digital game (SCDG) to motivate self-management behaviors of weight monitoring and physical activity in older adults with heart failure (HF).
- Trial name
- NCT03947983
- Testing
- Sensor-controlled digital game (SCDG), Sensor Only
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- University of Texas at Austin
Obesity
Pilot Study of Time Restricted Feeding as a Weight Loss Intervention
The circadian timing of Energy Intake (EI) has emerged as a key factor in the regulation of body weight. Studies have suggested that eating later in the evening or at night when the circadian system is promoting sleep adversely…
- Trial name
- NCT03571048
- Testing
- Reduced Calorie Diet (RCD), Time Restricted Feeding (TRF)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Aging
Health, Aging and Later-Life Outcomes
The purpose of this pilot research is to test the feasibility of two interventions focused on either reducing total calorie intake or reducing the total time that calories are ingested each day in older adults.
- Trial name
- HALLO-P (NCT05424042)
- Testing
- In-Person Caloric Restriction, Remote Caloric Restriction, Time-restricted
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Wake Forest University Health Sciences
Pharmacokinetics
Drug-Drug Interaction Study Between Colchicine and Ketoconazole
Ketoconazole is a potent inhibitor of the cytochrome P450 (CYP) 3A4 enzyme system, one of the enzyme systems responsible for the metabolism of colchicine.
- Trial name
- NCT00983216
- Testing
- Colchicine, Ketoconazole
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mutual Pharmaceutical Company, Inc.
Diabetic Ketoacidosis
Effectiveness of Subcutaneous Glargine On The Time To Closure of The Anion Gap in Patients Presenting to the Emergency Department With Diabetic Keto-acidosis
To determine if co-administration of subcutaneous (SQ)Insulin glargine in combination with intravenous (IV) insulin decreases the time to resolution of ketoacidosis and requirement for ICU admission compared to IV insulin with…
- Trial name
- GT-COG (NCT02006342)
- Testing
- Insulin Glargine, Regular Insulin
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
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