Clinical trials: Streptococcal Pharyngitis
Tonsillitis
Multicenter, Open, Randomized Comparative Trial To Compare The Efficacy Of Azithromycin Versus Amoxicillin In Children With Strep Throat
The primary objective was to compare the bacteriological efficacy at Day 10 of azithromycin pediatric suspension (20 mg/kg/day once daily for 3 consecutive days) versus amoxicillin pediatric suspension (50 mg/kg/day in 2 doses…
- Trial name
- NCT00643539
- Testing
- Zithromax, Clamoxyl
- Where
- 45 sites in France
- Volunteers
- 360 people
- Sponsor
- Pfizer
Pharyngitis
Comparison of Two Rapid Antigen Detection Tests for the Detection of Group-A Streptococcal Pharyngitis in Children
Group A streptococcal (GAS) pharyngitis in children represents a frequent diagnostic challenge in pediatric emergency departments, since isolated signs and clinical prediction rules are insufficient to accurately discriminate…
- Trial name
- NCT03099018
- Testing
- Sofia Strep A FIA
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Geneva
Streptococcal Sore Throat
In Vitro Diagnostic Device for the Detection of Strep A
The purpose of this trial is to show the accuracy and specificity of the Liat analyzer and assay for detecting Strep A at the point of care lab compared to culture.
- Trial name
- NCT02068469
- Where
- 5 sites in United States
- Volunteers
- 799 people
- Sponsor
- IQuum, Inc.
Group A Streptococcal Infection
Pilot Study of Strepic® Device for the Diagnosis of Group A Streptococcal Pharyngitis
The objective of this pilot study is to acquire images using the Strepic® device, a clinical prototype that has been designed specifically as a viable, low-cost, commercially realizable autofluorescence-based diagnostic test…
- Trial name
- NCT03777098
- Testing
- Strepic® Device
- Where
- United States
- Volunteers
- 426 people
- Sponsor
- David A. Talan
Streptococcus Pyogenes Infection, Pharyngitis
Clinical Performance of the Checkable Medical At-Home Strep A Test
The Checkable Medical At-Home Strep A Test is a rapid chromatographic immunoassay for the qualitative detection of Group A Strep (GAS) antigens from throat swabs.
- Conditions
- Streptococcus Pyogenes Infection, Pharyngitis, Respiratory Tract Infections
- Trial name
- NCT05107362
- Testing
- untrained lay user performs investigational diagnostic test
- Where
- 22 sites in United States
- Volunteers
- 1,347 people
- Sponsor
- Checkable Medical Inc
Group A Streptococcal Infection
CandyCollect Strep Throat Testing
This study will enroll children ages 5-17 who test positive for Group A Streptococcus (GAS) at a single clinic visit lasting approximately 30-60 minutes.
- Trial name
- NCT05175196
- Testing
- CandyCollect, Lollipop Swab
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Wisconsin, Madison
Pharyngitis
Pharyngitis,Group A Streptococcal Infection,Rapid Streptococcal Test,Throat Swab Culture
Comparison of Immunochromatographic Test for rapid detection of group A streptococcal antigen with culture in Pediatric patients.
- Trial name
- NCT02494219
- Testing
- Rapid Immunochromatographic streptococcal test
- Where
- Qatar
- Volunteers
- 906 people
- Sponsor
- Hamad Medical Corporation
Strept Throat
Rapid Strep Test Results
This is a prospective study seeks to determine how often a rapid antigens test for group A streptococcus is positive in healthy adults
- Trial name
- NCT04256694
- Testing
- Rapid Antigen Test for Group A Streptococcus
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kendall Healthcare Group, Ltd.
Group A Beta Hemolytic Streptococcal (GAS) Infection
Surveillance of Streptococcal Infections in Children in India
Information from this study is needed to plan an eventual trial of a GAS vaccine in India if and when one is available. A GAS vaccine is currently a priority of the Indian Council for Medical Research (ICMR), and this project has…
- Trial name
- NCT00342199
- Where
- 2 sites in India
- Volunteers
- 663 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Streptococcal Pharyngitis
Rapid POC GAS Diagnostics in the Paediatric ED
Randomized trial evaluating effectiveness of rapid point-of-care molecular GAS diagnostics as compared to standard culture-based techniques for the management of children aged 3-18 years of age presenting with sore throat to…
- Trial name
- NCT04247243
- Testing
- Rapid testing, Reference testing
- Where
- Canada
- Volunteers
- 392 people
- Sponsor
- Hamilton Health Sciences Corporation
Snoring, Strep Throat
Comparing Healthcare Utilization Between Adenotonsillectomy Patients With and Without Postoperative Antibiotic Use
This study is designed to look at healthcare utilization following the removal of tonsils and adenoids in pediatric patients who are not given an antibiotic following surgery.
- Trial name
- NCT01561703
- Testing
- Antibiotic
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Missouri-Columbia
Pharyngitis Acute
Point of Care Streptococcal Pharyngitis Testing
Sore throat is a common problem in children typically caused by viral or bacterial infections. While viral infections resolve without treatment, bacterial infections, such as "strep throat," are treatable with antibiotics.
- Trial name
- NCT03744832
- Testing
- Alere i™ Strep A assay, Throat culture
- Where
- Canada
- Volunteers
- 145 people
- Sponsor
- University of British Columbia
Throat Infection, Pharyngitis
To Check Effectiveness of Medistus Antivirus Lozenges for Cough
A thraot infection sometimes called pharyngitis can be either a bacterial or a viral infection leading to inflammation of the tissues of the throat that causes redness, pain and swelling of the walls and structure of the throat.
- Conditions
- Throat Infection, Pharyngitis, Sore Throat
- Trial name
- NCT04612829
- Testing
- Medistus Antivirus Lozenges
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Nutrin GmbH
Streptococcal Sore Throat
Once-daily Therapy for Streptococcal Pharyngitis
In some studies once daily amoxicillin therapy might be treatment of choice for Group A β-hemolytic Streptococcus pharyngitis in comparison with three to four times daily treatment with oral penicillin V.
- Trial name
- NCT01310361
- Testing
- Amoxicillin, Intramuscular Benzathin Penicillin G
- Where
- Iran
- Sponsor
- Azad University of Medical Sciences
Tonsillitis Streptococcal
Comparison of Intravenous Co-amoxiclav Versus Benzyl Penicillin
To compare intravenous Co-amoxiclav versus Benzyl penicillin in children with severe streptococcal tonsillitis in terms of efficacy, safety and cost effectiveness.
- Trial name
- NCT04215770
- Testing
- inj co-amoxiclav 50 units/kg/day vs inj Benzyl Penicillin 25000 units/kg/day
- Where
- Pakistan
- Volunteers
- 310 people
- Sponsor
- Combined Military Hospital, Pakistan
Pharyngitis
Safety and Efficacy of a Sore Throat Lozenge DORITHRICIN in Patients With Acute Pharyngitis
The aim of this multi-center, randomized, double-blind, placebo-controlled trial is to compare the efficacy and safety of Dorithricin® lozenge - a triple combination of 0.5 mg tyrothricin, 1.0 mg benzalkonium chloride, and 1.5 mg…
- Trial name
- DoriPha (NCT03323528)
- Testing
- Benzalkonium Chloride-Benzocaine Topical
- Where
- Germany
- Volunteers
- 321 people
- Sponsor
- Medice Arzneimittel Pütter GmbH & Co KG
Pharyngitis
APC-231 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) in Pediatric Patients With Strep Throat
The purpose of this study is to evaluate the efficacy and safety of APC-231 QD for 7 days in the bacteriological outcome at the Test of Cure Visit.
- Trial name
- NCT00100126
- Testing
- Amoxicillin Pulsatile Release Multiparticluate Sprinkle
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Advancis Pharmaceutical Corporation
Acute Otitis Media, Acute Sinusitis
Comparative Effectiveness of Antibiotics for Respiratory Infections
The purpose of this study is to identify and use patient centered outcomes to compare narrow-spectrum and broad-spectrum antibiotics for the treatment of common acute respiratory tract infections (ARTIs) in children.
- Conditions
- Acute Otitis Media, Acute Sinusitis, Group A Streptococcal Pharyngitis
- Trial name
- CEARI (NCT02297815)
- Testing
- Broad-spectrum antibiotics, Narrow-spectrum antibiotics
- Where
- United States
- Volunteers
- 2,472 people
- Sponsor
- Children's Hospital of Philadelphia
Urinary Tract Infection, Cellulitis
Perspectives on Antibiotics and Tracking Symptoms in Children
The study will assess families' perspectives and decision-making regarding the duration of oral antibiotic courses prescribed to children (4-17 years) who present with uncomplicated bacterial infections at the Royal Children's…
- Conditions
- Urinary Tract Infection, Cellulitis, Impetigo, Pharyngitis
- Trial name
- PATSy (NCT07093749)
- Testing
- Garmin Smartwatch
- Where
- Australia
- Volunteers
- 300 people
- Sponsor
- Murdoch Childrens Research Institute
Sydenham Chorea, Strep Throat
Dopaminergic Receptors in Sydenham's Chorea
Sydenham's chorea (SC) is a post-streptococcal, neuropsychiatric disorder associated with anti-neuronal antibodies. The investigators demonstrated elevated anti-D1-receptor (D1R) and anti-D2-receptor (D2R) antibodies titers…
- Trial name
- NCT04084977
- Testing
- Antibody detection
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Shaare Zedek Medical Center