Clinical trials: Streptococcus Pharyngitis
Streptococcus Group A
Mol Epi GrAS in Nicaragua
The purpose of this study is to determine the epidemiology of throat isolates of group A streptococci among 3-15 year-old children with pharyngitis (sore throat) living in Leon, Nicaragua.
- Trial name
- NCT00170521
- Where
- Nicaragua
- Volunteers
- 13,000 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Tonsillitis
A Multicenter, Randomized, Double-Blind, Double-Dummy Study Of Azithromycin SR Versus Amoxicillin For The Treatment Of Strep Throat In Children
The objective was to determine if a single 60 mg/kg dose of azithromycin SR was as safe and effective as a 10-day regimen of amoxicillin (45 mg/kg/day, given in divided doses every 12 hours) when used to treat children with strep…
- Trial name
- NCT00643149
- Testing
- amoxicillin, azithromycin SR
- Where
- 46 sites in United States, Canada and 3 more
- Volunteers
- 693 people
- Sponsor
- Pfizer
Tonsillitis, Pharyngitis
TELI TAD - Telithromycin in Tonsillitis in Adolescents and Adults
This is a multinational, randomized (1:1), double blind, comparator-controlled, 2 parallel treatment group study in subjects equal to or over 13 years of age, with Streptococcus pyogenes tonsillitis/pharyngitis (T/P).
- Trial name
- NCT00315549
- Testing
- Telithromycin, Penicillin
- Where
- 4 sites in United States, Argentina and 2 more
- Volunteers
- 233 people
- Sponsor
- Sanofi
Streptococcal Pharyngitis
GRoup A StrePtococcus
The purpose of the research is to help understand why some children become carriers of strep and whether children who are carriers need to be treated with antibiotics.
- Trial name
- GRASP (NCT01558804)
- Testing
- Identifying group A strep carriers
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Wisconsin, Madison
Tonsillitis
Multicenter, Open, Randomized Comparative Trial To Compare The Efficacy Of Azithromycin Versus Amoxicillin In Children With Strep Throat
The primary objective was to compare the bacteriological efficacy at Day 10 of azithromycin pediatric suspension (20 mg/kg/day once daily for 3 consecutive days) versus amoxicillin pediatric suspension (50 mg/kg/day in 2 doses…
- Trial name
- NCT00643539
- Testing
- Zithromax, Clamoxyl
- Where
- 45 sites in France
- Volunteers
- 360 people
- Sponsor
- Pfizer
Sydenham Chorea, Strep Throat
Dopaminergic Receptors in Sydenham's Chorea
Sydenham's chorea (SC) is a post-streptococcal, neuropsychiatric disorder associated with anti-neuronal antibodies. The investigators demonstrated elevated anti-D1-receptor (D1R) and anti-D2-receptor (D2R) antibodies titers…
- Trial name
- NCT04084977
- Testing
- Antibody detection
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Shaare Zedek Medical Center
Group A Streptococcal Pharyngitis
Group A Pharyngitis in Children: The GASPARD Study
Evaluate the necessity to treat with antibiotics GAS pharyngitis in children in Switzerland. The null hypothesis is that antibiotic treatment is not necessary for GAS pharyngitis in this population.
- Trial name
- GASPARD (NCT03264911)
- Where
- Switzerland
- Volunteers
- 360 people
- Sponsor
- Klara Posfay-Barbe
Group A Streptococcus
Strep A FIA Field Study, Sofia
To demonstrate the clinical performance of the Strep A FIA and Sofia, using throat swabs collected from symptomatic subjects.
- Trial name
- NCT02153008
- Where
- 7 sites in United States
- Volunteers
- 1,708 people
- Sponsor
- Quidel Corporation
Tonsillitis, Tonsillitis Streptococcal
Diagnosis of GABHS Tonsillitis - Comparison Between Culture From Tonsills and Culture From the Bucal Surface
Diagnosis of Group A beta hemolytic strep tonsillitis - cultre of tonsills (gold standard) culture from bucal surface (test)
- Trial name
- NCT03137823
- Testing
- throat culture
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Bait Balev Hospital
Group A Streptococcal Infection
CandyCollect Strep Throat Testing
This study will enroll children ages 5-17 who test positive for Group A Streptococcus (GAS) at a single clinic visit lasting approximately 30-60 minutes.
- Trial name
- NCT05175196
- Testing
- CandyCollect, Lollipop Swab
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Wisconsin, Madison
Sore Throat, Pharyngitis
APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat
The primary objective of this study is to evaluate the efficacy of APC 111 MP Tablet, 775 mg tablet, given orally (PO)once daily (QD) for 10 days compared to that of Penicillin VK, 250 mg PO four times daily (QID) for 10 days in…
- Conditions
- Sore Throat, Pharyngitis, Tonsillitis
- Trial name
- NCT00242281
- Testing
- APC-111 MP Tablet, 775 mg
- Where
- 41 sites in United States, Canada
- Volunteers
- 600 people
- Sponsor
- Advancis Pharmaceutical Corporation
Streptococcus Pyogenes Pharyngitis, Streptococcus Infection
A Strep Throat Controlled Human Infection Trial in Healthy Adults
This aim of this study is to further develop a new way to study the bacteria that causes pharyngitis (strep throat). The scientific name for this bacterium is Streptococcus pyogenes and it is commonly known as Strep A.
- Trial name
- CHIVAS-M1 (NCT06992141)
- Testing
- Streptococcus pyogenes M1UK strain MCRI0102
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Acute Sinusitis, Streptococcal Pharyngitis
Antimicrobial Stewardship for Primary Care Pediatricians
The purpose of the study is to determine if physician education coupled with audit and feedback of antibiotic prescribing can improve antibiotic prescribing by primary care clinicians.
- Conditions
- Acute Sinusitis, Streptococcal Pharyngitis, Pneumonia, Viral Infection
- Trial name
- PARTI (NCT01806103)
- Testing
- Antimicrobial Stewardship Bundle
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Children's Hospital of Philadelphia
Group A Streptococcus, Strep Throat
Sofia Strep A FIA Field Study
The purpose of this study is to demonstrate the ability of the Sofia Strep A FIA test and Sofia Analyzer to accurately detect a throat swab specimen for the presence or absence of Group A Streptococcus when compared to culture.
- Trial name
- NCT01494792
- Testing
- In Vitro Diagnositc aid for diagnosis
- Where
- 8 sites in United States
- Volunteers
- 2,090 people
- Sponsor
- Quidel Corporation
Group A Streptococcal Infection
Pilot Study of Strepic® Device for the Diagnosis of Group A Streptococcal Pharyngitis
The objective of this pilot study is to acquire images using the Strepic® device, a clinical prototype that has been designed specifically as a viable, low-cost, commercially realizable autofluorescence-based diagnostic test…
- Trial name
- NCT03777098
- Testing
- Strepic® Device
- Where
- United States
- Volunteers
- 426 people
- Sponsor
- David A. Talan
Tonsillitis
Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children
The primary objective of this study is to demonstrate the non-inferiority, at the assessment visit (V3 (D10/D14)), in terms of bacteriological efficacy of pristinamycin (PRI) administered for 4 days versus amoxicillin (AMX)…
- Trial name
- PRI-angine (NCT00393744)
- Testing
- pristinamycin, amoxicillin
- Where
- France
- Volunteers
- 395 people
- Sponsor
- Sanofi
Group A Streptococcus: B Hemolytic Pharyngitis
Detection of GABHS in Throat Gargle
The objective of this study is to investigate the use of patient throat gargle as an alternative to throat swabbing for the diagnosis of pharyngitis caused by Group A β-Hemolytic Streptococcus (GABHS) infection, also known as…
- Trial name
- NCT03231098
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Gargle Tech
Streptococcus Group A
Molecular Epidemiology of Streptococcus Pyogenes Among Children in Bamako, Mali
The purpose of this study is to learn more about sore throats caused by the germ Group A Streptococcus (GAS) or "Strep". When "Strep" causes a sore throat, it can be treated with medicines called antibiotics.
- Trial name
- NCT00305123
- Where
- Mali
- Volunteers
- 1,757 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Streptococcus Pyogenes Infection, Pharyngitis
Clinical Performance of the Checkable Medical At-Home Strep A Test
The Checkable Medical At-Home Strep A Test is a rapid chromatographic immunoassay for the qualitative detection of Group A Strep (GAS) antigens from throat swabs.
- Conditions
- Streptococcus Pyogenes Infection, Pharyngitis, Respiratory Tract Infections
- Trial name
- NCT05107362
- Testing
- untrained lay user performs investigational diagnostic test
- Where
- 22 sites in United States
- Volunteers
- 1,347 people
- Sponsor
- Checkable Medical Inc
Streptococcal Infections, Pharyngitis
Treatment of Group A Beta Hemolytic Streptococcal Pharyngitis in Children in Low Resource Settings
The purpose of this study was to compare the microbiological effects of two different treatments: a single dose of intramuscular benzathine penicillin G (IM BPG) vs.
- Trial name
- TOPS (NCT01156740)
- Testing
- Penicillin G, Benzathine, Amoxicillin
- Where
- 3 sites in Brazil, Croatia and 1 more
- Volunteers
- 558 people
- Sponsor
- Johns Hopkins University