Clinical trials: Streptococcus Pharyngitis
Snoring, Strep Throat
Comparing Healthcare Utilization Between Adenotonsillectomy Patients With and Without Postoperative Antibiotic Use
This study is designed to look at healthcare utilization following the removal of tonsils and adenoids in pediatric patients who are not given an antibiotic following surgery.
- Trial name
- NCT01561703
- Testing
- Antibiotic
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Missouri-Columbia
Tonsillitis, Pharyngitis
TELI TON - Telithromycin in Tonsillitis
This is a multinational, randomized (1:1), double blind, double dummy, comparator-controlled, 2 parallel treatment group study in subjects from 6 months to < 13 years of age, with Streptococcus pyogenes tonsillitis/pharyngitis…
- Trial name
- NCT00315042
- Testing
- Telithromycin (HMR3647), Penicillin
- Where
- 5 sites in United States, Argentina and 3 more
- Volunteers
- 314 people
- Sponsor
- Sanofi
Streptococcus Pyogenes Pharyngitis, Streptococcus Infection
A Strep Throat Controlled Human Infection Trial in Healthy Adults
This aim of this study is to further develop a new way to study the bacteria that causes pharyngitis (strep throat). The scientific name for this bacterium is Streptococcus pyogenes and it is commonly known as Strep A.
- Trial name
- CHIVAS-M1 (NCT06992141)
- Testing
- Streptococcus pyogenes M1UK strain MCRI0102
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Streptococcal Sore Throat
Once-daily Therapy for Streptococcal Pharyngitis
In some studies once daily amoxicillin therapy might be treatment of choice for Group A β-hemolytic Streptococcus pharyngitis in comparison with three to four times daily treatment with oral penicillin V.
- Trial name
- NCT01310361
- Testing
- Amoxicillin, Intramuscular Benzathin Penicillin G
- Where
- Iran
- Sponsor
- Azad University of Medical Sciences
Tonsillitis
Tonsillectomy in Recurrent Tonsillitis
The purpose of this study is to determine whether tonsillectomy is effective in preventing further streptococcal pharyngitis episodes in patients with recurrent tonsillitis.
- Trial name
- NCT00136877
- Testing
- (adeno)tonsillectomy
- Where
- Finland
- Volunteers
- 70 people
- Sponsor
- Oulu University Hospital
Sore Throat, Tonsillitis
Sore Throat in Primary Care - a Comparison of Phenoxymethylpenicillin and No Antibiotic Treatment
Sore throat is the second most common cause of antibiotic prescribing in primary care in Sweden. Guidelines for sore throat focus on identifying people with sore throat where there are 3 and 4 specified criteria and where near…
- Trial name
- SANT (NCT04083417)
- Testing
- Phenoxymethylpenicillin, No antibiotic treatment
- Where
- 6 sites in Sweden
- Volunteers
- 260 people
- Sponsor
- Katarina Hedin
Recurrent Tonsillitis
Evaluation of the Efficacy of Streptococcus Salivarius Evol12® in the Reduction of Recurrent Adenotonsillitis in Children
This prospective, multicenter, randomized, double-blind, placebo-controlled, cross-over clinical trial will evaluate the efficacy and safety of Streptococcus salivarius Evol12® (Bactoblis® Evol) in reducing the recurrence and…
- Trial name
- NCT07235826
- Testing
- Bactoblis® Evol (Streptococcus salivarius Evol12®)
- Where
- Italy
- Volunteers
- 216 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Streptococcal Infections, Pharyngitis
Treatment of Group A Beta Hemolytic Streptococcal Pharyngitis in Children in Low Resource Settings
The purpose of this study was to compare the microbiological effects of two different treatments: a single dose of intramuscular benzathine penicillin G (IM BPG) vs.
- Trial name
- TOPS (NCT01156740)
- Testing
- Penicillin G, Benzathine, Amoxicillin
- Where
- 3 sites in Brazil, Croatia and 1 more
- Volunteers
- 558 people
- Sponsor
- Johns Hopkins University
Group A Streptococcal Infection
Performance of Ellume·Lab Group A Strep Test Versus Culture for the Rapid Detection of Group A Streptococcus in Participants With Acute Pharyngitis
Participants who meet the eligibility criteria and who consent to participation or whose parents/legal guardian consent to their participation, will be enrolled in the study for a period of up to 14 days.
- Trial name
- NCT03693495
- Testing
- ellume·lab Group A Streptococcus Test, Bacterial Culture, Polymerase Chain Reaction (PCR)
- Where
- 4 sites in New Zealand
- Sponsor
- Ellume Pty Ltd
Streptococcal Infection, Pharyngitis
Assessment of Flocked Swabs for the Identification of Group A Streptococcal Pharyngitis
This is a study to to compare traditional fibre wound swabs to more recently developed flocked swabs for the identification of Group A streptococcal pharyngitis in children presenting to a children's emergency department.
- Trial name
- NCT00527852
- Testing
- Flocked swab
- Where
- Canada
- Volunteers
- 350 people
- Sponsor
- Children's Hospital of Eastern Ontario
Tonsillitis
Multicenter, Open, Randomized Comparative Trial To Compare The Efficacy Of Azithromycin Versus Amoxicillin In Children With Strep Throat
The primary objective was to compare the bacteriological efficacy at Day 10 of azithromycin pediatric suspension (20 mg/kg/day once daily for 3 consecutive days) versus amoxicillin pediatric suspension (50 mg/kg/day in 2 doses…
- Trial name
- NCT00643539
- Testing
- Zithromax, Clamoxyl
- Where
- 45 sites in France
- Volunteers
- 360 people
- Sponsor
- Pfizer
Pharyngitis Acute
Point of Care Streptococcal Pharyngitis Testing
Sore throat is a common problem in children typically caused by viral or bacterial infections. While viral infections resolve without treatment, bacterial infections, such as "strep throat," are treatable with antibiotics.
- Trial name
- NCT03744832
- Testing
- Alere i™ Strep A assay, Throat culture
- Where
- Canada
- Volunteers
- 145 people
- Sponsor
- University of British Columbia
Group A Streptococcal Infection
Performance of Ellume·Lab Group A Strep Test Versus Culture for the Rapid Detection of Group A Streptococcus in Patients With Acute Pharyngitis.
Participants who meet the eligibility criteria and who consent to participation or whose parents/legal guardian consent to their participation, will be enrolled in the study for a period of up to 14 days.
- Trial name
- NCT03171350
- Testing
- ellume.lab Group A Streptococcus Test
- Where
- 8 sites in Australia
- Volunteers
- 132 people
- Sponsor
- Ellume Pty Ltd
Streptococcal Sore Throat
In Vitro Diagnostic Device for the Detection of Strep A
The purpose of this trial is to show the accuracy and specificity of the Liat analyzer and assay for detecting Strep A at the point of care lab compared to culture.
- Trial name
- NCT02068469
- Where
- 5 sites in United States
- Volunteers
- 799 people
- Sponsor
- IQuum, Inc.
Recurrent Tonsillitis in Children
A Phase I/II to Assess Safety, Tolerability and Efficacy of DL-lactic Acid Syrup in Children With Recurrent Tonsillitis
The study objectives are to evaluate Tonsitin™ (10% Lactic Acid) safety, tolerability and preliminary efficacy, as a potent treatment for Recurrent Tonsillitis in children.
- Trial name
- NCT01988558
- Testing
- DL - Lactic Acid, Raspberry flavored syrup
- Where
- 3 sites in Israel
- Volunteers
- 51 people
- Sponsor
- Yali Pharmaceuticals
Tonsillitis, Tonsillitis Streptococcal
Diagnosis of GABHS Tonsillitis - Comparison Between Culture From Tonsills and Culture From the Bucal Surface
Diagnosis of Group A beta hemolytic strep tonsillitis - cultre of tonsills (gold standard) culture from bucal surface (test)
- Trial name
- NCT03137823
- Testing
- throat culture
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Bait Balev Hospital
Pharyngitis
Comparison of Two Rapid Antigen Detection Tests for the Detection of Group-A Streptococcal Pharyngitis in Children
Group A streptococcal (GAS) pharyngitis in children represents a frequent diagnostic challenge in pediatric emergency departments, since isolated signs and clinical prediction rules are insufficient to accurately discriminate…
- Trial name
- NCT03099018
- Testing
- Sofia Strep A FIA
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Geneva
Tonsillitis
A Multicenter, Randomized, Double-Blind, Double-Dummy Study Of Azithromycin SR Versus Amoxicillin For The Treatment Of Strep Throat In Children
The objective was to determine if a single 60 mg/kg dose of azithromycin SR was as safe and effective as a 10-day regimen of amoxicillin (45 mg/kg/day, given in divided doses every 12 hours) when used to treat children with strep…
- Trial name
- NCT00643149
- Testing
- amoxicillin, azithromycin SR
- Where
- 46 sites in United States, Canada and 3 more
- Volunteers
- 693 people
- Sponsor
- Pfizer
Streptococcal Pharyngitis
GRoup A StrePtococcus
The purpose of the research is to help understand why some children become carriers of strep and whether children who are carriers need to be treated with antibiotics.
- Trial name
- GRASP (NCT01558804)
- Testing
- Identifying group A strep carriers
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Wisconsin, Madison
Streptococcal Pharyngitis
Stopping Strep Throat With Antibodies in Healthy Adults.
This research group has previously established a safe and reliable model of experimental human streptococcal pharyngitis (a 'strep throat' human challenge model).
- Trial name
- CHIVAS-IgG (NCT07864350)
- Testing
- Streptococcus pyogenes M1 challenge strain, Intravenous immunoglobulin (IVIG)
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute