Clinical trials: Stress, completed
Posttraumatic Stress Disorder, Substance Abuse
Multicomponent Cognitive Behavioral Therapy(CBT) for Posttraumatic Stress Disorder (PTSD) and Substance Abuse
Purpose: To conduct a pilot study of a cognitive-behavioral treatment (CBT) for PTSD and substance abuse among persons with serious mental illness (SMI) treated in a community setting.
- Trial name
- PTSD/SUD (NCT01029197)
- Testing
- CBT and exposure therapy for PTSD, Treatment as Usual
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of North Carolina, Chapel Hill
Non Insulin Dependent Diabetes
Curcumin Supplementation and Patients With Type 2 Diabetes
Diabetes mellitus is the most common endocrine disorder, causes many complications such as micro- and macro-vascular diseases. Various kinds of antidiabetic drugs have been developed, but most of them have side effects.
- Trial name
- NCT02529982
- Testing
- Curcumin
- Where
- Iran
- Volunteers
- 44 people
- Sponsor
- National Nutrition and Food Technology Institute
Peripheral Diabetic Neuropathy
Assessment of Antioxidant Therapy on Oxidative Stress Biomarkers in Type 2 Diabetic Patients With Neuropathy
Type 2 DM subjects having numbness, tingling and paresthesia in hands and feet (neuropathy) will be recruited. Screening of neuropathy will be done by Michigan screening instrument.
- Trial name
- RCT (NCT06131918)
- Testing
- Resveratrol, Alpha lipoic acid, Super oxide dismutase, Resveratrol, Alpha lipoic acid
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Khyber Medical University Peshawar
Parkinson's Disease
Mindfulness Based Stress Reduction for Parkinson's Disease: A Longitudinal Study
To investigate the efficacy of Mindfulness-based Stress Reduction (MBSR) to improve quality of life, cognition, and mood, as well as to determine the longevity of the treatment response in individuals with Parkinson's disease…
- Trial name
- MBSR (NCT03998462)
- Testing
- Mindfulness Based Stress Reduction, Psychoeducational Supportive Care
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- VA Office of Research and Development
Hypertension, Sodium Excess
Effects of Salt on Serum Osmolarity and Hemodynamics Parameters
Diets containing excessive salt (>12 g/day) have negative effects on kidney and cardiovascular system. Considering this known fact, the investigators aimed to study if the amount of the water taken with excessive salt had any…
- Conditions
- Hypertension, Sodium Excess, Oxidative Stress, Inflammation
- Trial name
- NCT03314727
- Testing
- High salt (NaCl) intake
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Koç University
Psychological Stress
Mindfulness Training in Military Spouses
This project aims to contextualize the delivery of mindfulness training for military spouses and evaluate its effectiveness on measures of executive functions and psychological well-being.
- Trial name
- NCT03308344
- Testing
- Mindfulness training
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Miami
Major Depressive Disorder, Generalized Anxiety Disorder
The Modular Protocol for Mental Health (MPMH)
Currently, our best psychological treatments for anxiety and mood disorders only focus on individual diagnoses. So, there are separate treatments for Panic Disorder, or Depressive Disorder, or Social Anxiety, etc.
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Posttraumatic Stress Disorder, Social Anxiety Disorder
- Trial name
- MPMH (NCT03143634)
- Testing
- The Modular Protocol for Mental Health, Treatment-as-usual
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Anxiety Disorders, Mood Disorders
Mindfulness-Based Stress Reduction (MBSR) and Transcranial Direct Current Stimulation (tDCS)
Ideal interventions for the older aged population would be those that are easily accessible and associated with minimal burden on family members, the healthcare system and the individuals themselves.
- Conditions
- Anxiety Disorders, Mood Disorders, Transcranial Direct Current Stimulation, tDCS
- Trial name
- NCT03680664
- Testing
- Active tDCS, MBSR
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Centre for Addiction and Mental Health
Laughter Yoga, Premenstrual Syndrome-PMS
Laughter Yoga and Sleep Hygiene Training for College Students With Premenstrual Syndrome
This study aims to evaluate the effects of laughter yoga and sleep hygiene training on premenstrual syndrome (PMS) symptoms, perceived stress levels, and sleep quality among nursing students.Premenstrual syndrome is a common…
- Conditions
- Laughter Yoga, Premenstrual Syndrome-PMS, Stress, Sleep Quality
- Trial name
- LYSHPMS (NCT07599436)
- Testing
- Supportive Care
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Gazi University
PTSD, Panic Attacks
Exposure Therapy for Veterans With PTSD and Panic Attacks (Phase 1)
To evaluate the feasibility, acceptability and effectiveness of Multiple Channel Exposure Therapy-Veterans (MCET-V) as a treatment for returning service members with comorbid posttraumatic stress disorder (PTSD) and panic…
- Trial name
- NCT01551199
- Testing
- Multiple Channel Exposure Therapy- Veterans
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- VA Office of Research and Development
Mild Depression, Anxiety State
MyCompass in a Swedish Context - an Automated Self-help Intervention Targeting Mental Health Problems
The study present findings from the implementation of myCompass, a fully automated self-help intervention of Australian origin for mild to moderate anxiety and depression, in a Swedish context.
- Conditions
- Mild Depression, Anxiety State, Sleep Disturbance, Stress, Psychological
- Trial name
- NCT03659630
- Testing
- MyCompass, Comparison group
- Volunteers
- 837 people
- Sponsor
- Karolinska Institutet
Corneal Endothelial Cell Loss, Ozone Therapy
Effect of Systemic Ozone Therapy on Corneal Endothelium
This study evaluates the safety of systemic ozone therapy on the corneal endothelium, a vital non-renewable tissue that maintains corneal transparency.
- Trial name
- OZON-CORNEA (NCT07718100)
- Testing
- Systemic Ozone Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Obesity, Non-insulin-dependent Diabetes Mellitus
Effects of HBO Therapy on Muscular Insulin Resistence in Type 2 Diabetes
Hyperbaric oxygen therapy (HBO) is applied for several diseases. The effect on insulin sensitivity is yet unknown. Hypothesis: HBO therapy improves insulin sensitivity in patients.
- Trial name
- NCT01472328
- Testing
- HBO therapy, Hyperbaric room air
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Pain, Fear
The Effect of Buzzy® and a Stress Ball on Reducing Pain and Fear During Peripheral Intravenous Cannulation in Children
This study aims to compare the effects of Buzzy®, a device that applies cold and vibration, and a stress ball on pain and fear during intravenous catheter insertion in children aged 7-12 years.
- Conditions
- Pain, Fear, Pain Management
- Trial name
- NCT07851909
- Testing
- Buzzy, Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Permeability; Increased
PRObiotic and Stress-related PERmeability
This is a single-site exploratory study aiming to demonstrate the effect of a fresh fermented dairy drink containing a probiotic strain on stress-related intestinal hyperpermeability in students defending a bachelor's or master's…
- Trial name
- ProSPer (NCT03408691)
- Testing
- Fresh fermented dairy drink containing probiotic strain, Acidified dairy drink without ferment
- Where
- Belgium
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pain
Safety and Effects on Responses to Stress and Pain of Natural Medical Marijuana Products
This proposal aims to systematically examine the safety and pharmacokinetic/pharmacodynamic profile and the physiologic, neuroendocrine and behavioral stress and pain responses to acute single doses and repeated dosing of oral…
- Trial name
- NCT04226690
- Testing
- Active CBD/THC Dose 1, Active CBD/THC Dose 2
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Aortic Rupture
In Vivo Evaluation of Growth and Risk of Rupture of Dilated Ascending Aorta Using 4D Cardiac Magnetic Resonance
Ascending aorta aneurysmal disease is common and can be complicated by dissection or rupture. There is substantial variation in individual aneurysm progression: established risk factors for an accelerated aneurysm growth rate…
- Trial name
- NCT03172390
- Testing
- 4D Cardiac Magnetic Resonance
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Inflammation, Healthy
Impact of Cottonseed Oil on Oxidative Stress, Inflammation, and Metabolism
Recent research evidence suggests that cottonseed oil (CSO) may have both direct and indirect anti-inflammatory and anti-oxidative impacts linked to bioactive components of CSO and favorable alterations in lipid metabolism.
- Conditions
- Inflammation, Healthy, Oxidative Stress, Metabolic Syndrome
- Trial name
- NCT05439590
- Testing
- High dose CSO, Low dose CSO, Low dose OO
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Montana State University
Substance Use Disorder (SUD), Anxiety Disorder Generalized
Mindfulness-Based Psychoeducation With Substance Use and Anxiety Disorders
This observational study evaluated a structured mindfulness-based psychoeducation program focused on emotional awareness, forgiveness, and self-awareness to reduce anxiety and support recovery from substance use in adults.
- Trial name
- MBPASA (NCT07483918)
- Testing
- Mindfulness-Based Psychoeducation Program
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Bout Me Healing
Coronavirus, Depression
Social Media Use During COVID-19
The investigators plan to conduct a cross-sectional survey to examine how social media use during COVID-19 relates to: (1) information management, (2) assessment of the situation, and (3) affect.
- Conditions
- Coronavirus, Depression, Anxiety, Stress
- Trial name
- NCT04305574
- Testing
- Use of social media during COVID-19
- Where
- Singapore
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- Jean Liu
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