Clinical trials: Stress Disorder, Post-Traumatic
Post-traumatic Stress Disorder
Clinician-Assisted Videofeedback Exposure-Approach Therapy (CAVEAT) Trial
The first study proposed is a small (n= 10 to 12 maximum) open feasibility trial of CAVEAT which is a 16-session manualized brief psychotherapy prototcol that is designed to help mothers of infants and young children, whereby the…
- Trial name
- CAVEAT (NCT05927324)
- Testing
- CAVEAT
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Depression, Anxiety
Self-Defense Training in Women With Trauma
Previous research has shown that self-defense training can lead to gains in women's assertiveness, self-esteem, self-efficacy, and physical competence, and decreases in anxiety, helplessness, fear, and avoidant behaviors.
- Conditions
- Depression, Anxiety, Stress Disorders, Post-Traumatic
- Trial name
- NCT01380379
- Testing
- Life skills and self-defense training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Stanford University
PTSD
Substance P Antagonist in the Treatment of Posttraumatic Stress Disorder
This study, conducted at the NIH and the Mount Sinai School of Medicine, will examine the effectiveness of a substance P or NK1 antagonist study drug known as GR205171 in treating the symptoms of posttraumatic stress disorder…
- Trial name
- NCT00383786
- Testing
- NK1 Antagoist (GR205171), Psychophysiology (Trauma Script), Psychophysiology (Verbal Threat)
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Baylor College of Medicine
Posttraumatic Stress Disorder
Meeting the Needs of Pregnant Women With PTSD in Prenatal Care
The objectives of this research study are to screen 750 pregnant women at risk of trauma-related stress symptoms, and adapt and test an evidence-based intervention for pregnant women with PTSD and sub-threshold PTSD symptoms…
- Trial name
- NCT02807662
- Testing
- Adapted Seeking Safety Intervention
- Volunteers
- 149 people
- Sponsor
- University of Massachusetts, Worcester
Post-traumatic Stress Disorder (PTSD) Among Road Traffic Injury Victims
Impact of Capacity Building of Healthcare Workers on Management of Post-Traumatic Stress Disorder
This is a community- and hospital-based interventional study consisting of two interventions: Capacity building of healthcare workers (HCWs) in the intervention group (Buea Regional Hospital, selected by simple random…
- Trial name
- NCT07110727
- Testing
- Two days, role play, adult interactive capacity building sessions of healthcare workers on PTSD screening and management. Pre/posttest and change in practice in screening will be used for evaluation
- Where
- 3 sites in Cameroon
- Volunteers
- 70 people
- Sponsor
- University of Buea
Stress Disorders, Post-Traumatic
Evaluation of PTSD Family Coach, a Mobile Phone App for Family Members of Individuals With PTSD
The proposed pilot study is designed to test the feasibility, acceptability, and potential effectiveness of a mobile phone application (app) developed by the VA National Center for PTSD (VA NCPTSD) for use by family members of…
- Trial name
- NCT02486705
- Testing
- PTSD Family Coach Full, PTSD Family Coach Basic
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Perinatal Loss, Grief
Digital Perinatal Bereavement Support Program for Women After Pregnancy Loss
This study aims to evaluate the effectiveness of a digital perinatal bereavement support program designed for women who have experienced pregnancy loss.
- Conditions
- Perinatal Loss, Grief, Depression Anxiety Disorder
- Trial name
- DPBSP (NCT07545551)
- Testing
- Supportive Care
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Gazi University
Traumatic Injury, Posttraumatic Stress Disorder
CHW-Enhanced Trauma Recovery
This pilot study will evaluate the feasibility, acceptability, and preliminary effectiveness of the Trauma Resilience and Recovery Program Plus (TRRP+), a Community Health Worker-enhanced intervention designed to improve…
- Conditions
- Traumatic Injury, Posttraumatic Stress Disorder, Depression, Social Determinants of Health
- Trial name
- TRRP+ (NCT07818161)
- Testing
- CHW support
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Medical University of South Carolina
Mental Health Disorder, PTSD
Psychosocial and Economic Impacts of Narrative Exposure Therapy for Violence Survivors in Eastern DRC
The objective of the study is to evaluate the impact of Narrative Exposure Therapy (NET) delivered by local counselors, on the mental health and socio-economic empowerment of survivors of Sexual and Gender Based Violence (SGBV)…
- Conditions
- Mental Health Disorder, PTSD, Depression Anxiety Disorder, Gender-based Violence
- Trial name
- NCT04841031
- Testing
- NET Treatment, Alternative Intervention
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 1,053 people
- Sponsor
- World Bank
PTSD
Efficacy of Compassion Focused Therapy in Group for Posttraumatic Stress Disorder
The purpose of this study is to determine the efficacy of a 8-week program of Compassion Focused Therapy in Group comparing to Supportive Cognitive Behavioral Therapy in Group for patients with Posttraumatic Stress Disorder.
- Trial name
- GCFT-PTSD (NCT03154931)
- Testing
- CBT-SG, CFT-G
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Sao Paulo General Hospital
Depression, Post-traumatic Stress Disorder
Evaluating Implementation Strategies to Scale-up Transdiagnostic Evidence-based Mental Health Care in Zambia
This study utilizes a Hybrid Type 1 multi-arm parallel group randomized control design to compare the effectiveness of an evidence-based treatment (CETA) delivered either in-person or via telephone, compared with a treatment as…
- Conditions
- Depression, Post-traumatic Stress Disorder, Anxiety, Substance Abuse
- Trial name
- NCT03458039
- Testing
- In-person CETA, Telephone CETA, Treatment as Usual (TAU)
- Where
- Zambia
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
PTSD, Depression
Synchronized Transcranial Magnetic Stimulation for PTSD
The investigators propose a small, two-site, sham-controlled pilot study of synchronized Transcranial Magnetic Stimulation (sTMS) in patients with comorbid post-traumatic stress disorder (PTSD) and depression.
- Trial name
- sTMS (NCT02981381)
- Testing
- NEST-1, NEST-2
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Providence VA Medical Center
Posttraumatic Stress Disorder
Mind-Body Skills Groups for the Treatment of War-Related Trauma in Children in Gaza
The objective of this study is to determine whether participation in a mind-body skills program by war-traumatized children in Gaza will result in improvement of posttraumatic stress symptoms, depression, and decreased…
- Trial name
- NCT01595477
- Testing
- Mind-Body Skills Group
- Where
- Israel
- Volunteers
- 114 people
- Sponsor
- The Center for Mind-Body Medicine
Traumatic Brain Injury (TBI), Post Traumatic Stress Disorder (PTSD)
Occupational Therapy Driving Intervention for Returning Combat Veterans.
Driving is a portal into general life functioning, and impaired driving skill can pose a serious threat to the combat veterans (CV), passengers and others; and involves increased risk of subsequent injuries, medical expenses and…
- Trial name
- NCT02764983
- Testing
- Driving Behavior Interview, Fitness-to-Drive Screening Measure, Clinical Driving Assessment
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Florida
Fibromyalgia, Psychological Trauma
Augmentation of EMDR With tDCS in the Treatment of Fibromyalgia
Fibromyalgia (FM) is a generalized, widespread chronic pain disorder and has an estimated prevalence of 2%-4% in the general population.
- Conditions
- Fibromyalgia, Psychological Trauma, Depressive Symptoms, Anxiety
- Trial name
- NCT04084795
- Testing
- Eye Movement Desensitization and Reprocessing therapy, transcranial Direct Current Stimulation
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Parc de Salut Mar
Working Memory, Consolidation/Recconsolidation Memory
Theories of Working Memory and Consolidation/RECOnsolidation in the Process of Resorption of Post-traumatic Symptoms.
EMDR is a psychotherapeutic approach recommended by the World Health Organization (WHO) for the treatment of disorders such as post-traumatic stress disorder, anxiety, depression and, more generally, psychological distress.
- Conditions
- Working Memory, Consolidation/Recconsolidation Memory, Eye Movement Desensitization and Reprocessing, Alterning Bilateral Stimulation
- Trial name
- NCT06469333
- Testing
- Eye movements (EM), Auditory stimulations, Tactile stimulations
- Where
- France
- Volunteers
- 154 people
- Sponsor
- University of Lorraine
Schizophrenia, Schizoaffective Disorder
Get Moving and Get Well - Pilot Study
Individuals with serious mental illness have greater morbidity from physical illness and mortality than the general population, but tend not to initiate or sustain engagement in health promotion interventions.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depression
- Trial name
- GMGWP (NCT01884025)
- Testing
- Get Moving and Get Well, Health and Humor Class
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD, Post-traumatic Stress Disorder
Neurofeedback Effectiveness Trial in PTSD
This study is an effectiveness trial investigating neurofeedback (NFB) in adults with PTSD (Post-Traumatic Stress Disorder). Participants will be randomly assigned to one of two treatment conditions - i) NFB, or ii) wait list.
- Conditions
- PTSD, Post-traumatic Stress Disorder, Cognitive Dysfunction, Cognitive Deficit
- Trial name
- NCT04654130
- Testing
- Neurofeedback
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Depression, Post Traumatic Stress Disorder
The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry
While effective interventions for depression exist, their success rates are unsatisfactory and their provision is haphazard. The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Depression Hub will improve…
- Conditions
- Depression, Post Traumatic Stress Disorder, Bipolar Disorder, Mood Disorder
- Trial name
- NCT02443636
- Where
- Canada
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Perinatal Mental Health, Reproductive Behavior
Women's Reproductive Choices and Mental Health During Pregnancy and After Birth in Wartime Ukraine
The goal of this observational study is to learn how war affects reproductive decisions and perinatal mental health in Ukrainian women.
- Conditions
- Perinatal Mental Health, Reproductive Behavior, Women, Cohort Studies
- Trial name
- NCT07551934
- Testing
- Psychological Assessment, Routine Clinical Data Collection
- Where
- Ukraine
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Taras Shevchenko National University of Kyiv
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