Clinical trials: Stress Disorder, Post-Traumatic
PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction
Trifecta Research Study
This observational study evaluates the impact of Ibogaine-Magnesium (IM), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), Magnetic e-Resonance Therapy (MeRT), and Physiological Supplementation (PS) on posttraumatic stress disorder…
- Conditions
- PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction, Brain Injury, Depression - Major Depressive Disorder
- Trial name
- NCT07717866
- Testing
- Magnetic e-Resonance Therapy (MeRT), Ibogaine Hydrochloride with Magnesium Sulfate, 5-methoxy-N,N-dimethyltryptamine
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Axial Therapeutic Research
Obstructive Sleep Apnea (OSA), Post-Traumatic Stress Disorder (PTSD)
Comparison Study Using APAP With and Without SensAwake in Patients With OSA and PTSD
The purpose of this research is to examine the application of AutoCPAP with and without SensAwake in subjects with OSA and Post-Traumatic Stress Disorder (PTSD), and evaluate whether patients achieve better sleep quality and…
- Trial name
- NCT02549508
- Testing
- AutoCPAP with SensAwake On, AutoCPAP with SensAwake Off
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Fisher and Paykel Healthcare
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Post-traumatic Stress Disorder, Adjustment Disorders
Pivotal Trial of SAT-014 for Trauma and Stressor-Related Disorder Symptoms
The aim of this study is to evaluate the efficacy of SAt-014, a software as a medical device (SaMD), in alleviating symptoms of trauma and stressor-related disorders in patients with post-traumatic stress disorder (PTSD) or…
- Trial name
- NCT06734858
- Testing
- SAT014, Control
- Where
- 5 sites in South Korea
- Volunteers
- 110 people
- Sponsor
- S-Alpha Therapeutics, Inc.
Post-traumatic Stress Disorder, Post Traumatic Stress Disorder
A Clinical Trial of PRAX-114 in Participants With Post-Traumatic Stress Disorder
This trial is comprised of a 4-week randomized, double-blind, placebo-controlled treatment period followed by an optional 8-week open-label extension (OLE) period.
- Conditions
- Post-traumatic Stress Disorder, Post Traumatic Stress Disorder, Stress Disorder, Stress Disorders, Post-Traumatic
- Trial name
- NCT05260541
- Testing
- 60 mg PRAX-114 or 40 mg PRAX-114, 40 mg PRAX-114
- Where
- 17 sites in United States
- Volunteers
- 11 people
- Sponsor
- Praxis Precision Medicines
PTSD
OM and Trauma Study
The primary purpose of this study is to use an unblinded, uncontrolled, 1-month interventional single group pilot study, to assess the possibility of Orgasmic Meditation practice being used as a possible intervention for PTSD.
- Trial name
- OMTP (NCT05577377)
- Testing
- Orgasmic Meditation
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Institute of OM Foundation
PostTraumatic Stress Disorder, Sleep Disorder
NightWare Open Enrollment Study
This study will provide measures of safety and efficacy of the NightWare digital therapeutic system (iPhone + Apple watch + proprietary application) for the treatment of nightmare disorder associated with post-traumatic stress…
- Conditions
- PostTraumatic Stress Disorder, Sleep Disorder, Stress Disorder, Sleep Initiation and Maintenance Disorders
- Trial name
- NWOES (NCT03828656)
- Testing
- NightWare Therapeutic System
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- NightWare
PTSD
Lu AG06466 in Participants With Post Traumatic Stress Disorder (PTSD)
The purpose of this study is to investigate the effect of Lu AG06466 after multiple doses of 30 milligrams (mg) in participants with PTSD.
- Trial name
- NCT04597450
- Testing
- Lu AG06466
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- H. Lundbeck A/S
Stress Disorders, Post-Traumatic, Anxiety Disorders
Ketamine Infusion Therapy for the Treatment of PTSD in Paramedics
This is an observational study to assess the change in several psychological screening tools before and after a series of six ketamine infusions in paramedics who suffer from post traumatic stress disorder as a result of working…
- Trial name
- NCT03947099
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Klarisana Physician Services PLLC
Post Traumatic Stress Disorder
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD
This study is evaluating the safety and efficacy of TSND-201 in adults with PTSD. Eligible participants will enter a 4-week Treatment Period where they will be randomized 1:1:1 to receive one of two doses of TSND-201 or placebo…
- Trial name
- EMPOWER-2 (NCT07836647)
- Testing
- TSND-201
- Where
- 9 sites in United States
- Volunteers
- 300 people
- Sponsor
- Transcend Therapeutics
PTSD
Safety and Efficacy of 50 mg NYX-783 QD vs. Placebo in PTSD
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of 50 mg NYX-783 Once Daily Compared to Placebo in Participants with Post-Traumatic Stress Disorder (PTSD)
- Trial name
- NCT05181995
- Testing
- NYX-783
- Where
- 37 sites in United States
- Volunteers
- 121 people
- Sponsor
- Aptinyx
PTSD
Safety and Efficacy Study of TNX-102 SL in Subjects With Military-Related PTSD and Related Conditions
This is a 12-week, multicenter, randomized, double-blind, placebo-controlled, fixed-dose, parallel-group study that will investigate the efficacy and safety of two doses of TNX-102 SL -a sublingual formulation of cyclobenzaprine.
- Trial name
- AtEase (NCT02277704)
- Testing
- TNX-102 SL
- Where
- 23 sites in United States
- Volunteers
- 245 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Post Traumatic Stress Disorder
Pilot Study of PRX-03140 to Assess Safety for Use in Adult Subjects With Post Traumatic Stress Disorder
This is a clinical study for adult subjects with Post Traumatic Stress Disorder.
- Trial name
- NCT01492699
- Testing
- PRX-03140
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Alachua Government Services, Inc.
Posttraumatic Stress Disorder
Clinical Trial to Preliminarily Assess the Safety and Feasibility of SAT-014, a Software for Alleviating Symptoms of Trauma and Stress-related Disorders
Failure to adapt to stress leads to functional impairments in various areas, including social, occupational, educational, and other significant domains, necessitating therapeutic intervention.
- Trial name
- NCT06439407
- Testing
- SAT-014(Software as Medical Device)
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- S-Alpha Therapeutics, Inc.
PTSD, Post Traumatic Stress Disorder
Feasibility of a Digital Therapeutic for Adults With Posttraumatic Stress Disorder (PTSD)
This study is exploring the efficacy of a digital therapeutic app in reducing symptoms of posttraumatic stress disorder (PTSD) in adults.
- Trial name
- NCT06868446
- Testing
- OTX-601 Digital Therapeutic - Version 1, OTX-601 Digital Therapeutic - Version 2, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oui Therapeutics, Inc.
Post-Traumatic Stress Disorder
Safety and Efficacy of NYX-783 in Subjects With Post-Traumatic Stress Disorder
To evaluate the safety, tolerability, and response profile of NYX-783 in a Post-Traumatic Stress Disorder population.
- Trial name
- NCT04044664
- Testing
- NYX-783
- Where
- 37 sites in United States
- Volunteers
- 160 people
- Sponsor
- Aptinyx
Post Traumatic Stress Disorder
A Single, Ascending Dose Evaluation of the Safety, Pharmacokinetics of Methylone in Healthy Subjects
This is an open-label, single, ascending dose study evaluating the PK and safety of methylone in healthy subjects.
- Trial name
- NCT06303648
- Testing
- Methylone
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Transcend Therapeutics
Post-Traumatic Stress Disorder
Phase II Study of BNC210 in PTSD
This is a randomized, double-blind, placebo-controlled study, evaluating the effects of BNC210 versus placebo on the symptoms of Post-Traumatic Stress Disorder, as measured by the Clinician-Administered PTSD Scale for DSM-5…
- Trial name
- RESTORE (NCT02933606)
- Testing
- BNC210
- Where
- 25 sites in United States, Australia
- Volunteers
- 193 people
- Sponsor
- Bionomics Limited
Post-Traumatic Stress Disorder (PTSD)
The PRISM Pilot Trial for Post-Traumatic Stress Disorder
A Prospective, Single-Arm, Open-Label Pilot Trial, to Assess Safety and Effectiveness of Process-Instructed Self neuro-Modulation ("Prism"), as an Adjunct to Standard of Care, in Subjects with Post-Traumatic Stress Disorder (PTSD)
- Trial name
- NCT04891614
- Testing
- PRISM
- Where
- 5 sites in United States, Israel
- Volunteers
- 87 people
- Sponsor
- GrayMatters Health Ltd.
Post Traumatic Stress Disorder
Exploring Clinical Study Experiences of People With Post Traumatic Stress Disorder
Participation in post traumatic stress disorder observational study serves as a crucial contribution to advancing medical knowledge and refining the care provided to individuals facing similar health challenges.
- Trial name
- NCT06146049
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.