Clinical trials: Stress Disorder, Post-Traumatic
Acute Pain, Wound Care
RCT: Fentanyl Plus Ketamine Versus Fentanyl Alone for Acute Burn Pain
The Ketamine for Acute Pain in Burns study is a randomized, double-blind, parallel group trial (RCT) with active control (usual care) contrasting the efficacy and safety of "Ketamine Plus Opiate-based usual care" (O+K) with the…
- Conditions
- Acute Pain, Wound Care, Posttraumatic Stress Disorder
- Trial name
- NCT03305055
- Testing
- ketamine, Fentanyl
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University
Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder
Empowering Perinatal Adolescents Through Writing
This is a feasibility and acceptability study of Written Exposure Therapy (WET) for PTSD in pregnant and postpartum adolescents and youth with PTSD.
- Conditions
- Post-Traumatic Stress Disorder in Adolescence, PTSD - Post Traumatic Stress Disorder, PTSD and Trauma-related Symptoms, Pregnancy and PTSD
- Trial name
- EMPWR (NCT06771817)
- Testing
- Written Exposure Therapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Texas Southwestern Medical Center
Intensive Care Unit, SARS-CoV2
Assessment of SARS-CoV-2 Effect on Post-traumatic Stress of Patients Hospitalized in Intensive Care Unit
Patients admitted to the intensive care unit develop psychiatric disorders, such as anxiety, depression or post-traumatic stress disorder, which can be prolonged.
- Trial name
- FAMILY-COVID (NCT04872049)
- Where
- France
- Volunteers
- 264 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Posttraumatic Stress Disorder (PTSD)
Personalized Repetitive Transcranial Magnetic Stimulation (PrTMS) for Treatment of Post-Traumatic Stress Disorder (PTSD)
This study is testing a personalized form of brain stimulation called PrTMS as a treatment for post-traumatic stress disorder (PTSD) in military service members and veterans.
- Trial name
- NCT07526285
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Posttraumatic Stress Disorder (PTSD)
Non Invasive Brain Stimulation for PTSD
This study is designed to identify changes in the brain that underlie symptoms of combat-related PTSD using brain imaging (fMRI).
- Trial name
- NCT02442843
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Stress Disorders, Post-Traumatic
The Effects of Home-Based Telemental Health for Rural Veterans With PTSD
The intent of this study is to assess whether cognitive functioning improves as Post-Traumatic Stress Disorder (PTSD) symptoms decrease as a step toward developing an objective measure of PTSD improvement.
- Trial name
- HBTMH (NCT02295410)
- Testing
- CPT
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- VA Pacific Islands Health Care System
Post-Traumatic Stress Disorder, Mental Disorders
The Trauma Recovery and Empowerment Model for Treating Post-Traumatic Stress Disorder in Women
This study will determine the effectiveness of the Trauma Recovery and Empowerment Model in reducing the severity of post-traumatic stress disorder symptoms in women with mental disorders and who have experienced sexual or…
- Conditions
- Post-Traumatic Stress Disorder, Mental Disorders, Depression
- Trial name
- TREM (NCT00183716)
- Testing
- Trauma Recovery and Empowerment Model (TREM), Usual care
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Trauma, PTSD
Posttraumatic Stress Symptoms Among Rescuers at Risk
This cross-sectional, anonymous online survey aims to examine how salient variables influence PTSS, well-being, and suicidal ideation across the following professions of rescue workers: firefighters, ambulance personnel, police…
- Conditions
- Trauma, PTSD, Self Efficacy, Coping Skills
- Trial name
- NCT03842553
- Testing
- No Intervention: anonymous online survey
- Where
- Switzerland
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- University of Bern
Posttraumatic Stress Disorder With Attention Defic
Atomoxetine and Executive Function in PTSD
Attention deficits (AD) frequently co-occur with posttraumatic stress disorder (PTSD). The presence of AD is associated with greater PTSD clinical severity and poorer clinical outcomes.
- Trial name
- NCT06573970
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD, Alcohol Use Disorder
Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems
The investigators propose to conduct a clinical trial to evaluate sertraline treatment efficacy in a large sample of military veterans with a dual diagnosis of PTSD and Alcohol Use Disorder who are receiving Cognitive and…
- Trial name
- DDx (NCT02504931)
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Child Abuse, Sexual, Post-Traumatic Stress Disorder
Body-Oriented Therapy for Sexual Abuse Recovery
The purpose of this study is to examine and compare the effects of two body therapy approaches in women who have experienced child sexual abuse.
- Conditions
- Child Abuse, Sexual, Post-Traumatic Stress Disorder, Dissociation
- Trial name
- NCT00097305
- Testing
- Body-Oriented Therapy, Standardized Massage Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Post Traumatic Stress Disorder
Trauma Treatment in Norwegian Child Advocacy Centers
Norwegian child and advocacy centers´ core activities include both forensic services (e.g., forensic interviews) and follow-up services (e.g., treatment), aiming to coordinate the different services involved in each case to…
- Trial name
- NCT05314829
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT)
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Critical Illness, Length of Stay
Advantages and Disadvantages of Long Term Sedation in Intensive Care Unit Patients
The purpose of the study is to determine whether sedation of the critical ill patient prolongs the time receiving mechanical ventilation.
- Conditions
- Critical Illness, Length of Stay, Respiration, Artificial, Intensive Care Units
- Trial name
- NCT00466492
- Testing
- Sedation or no sedation during mechanical ventilation
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Odense University Hospital
Post-traumatic Stress Disorder
Treatment of PTSD by Reduction of Traumatic Memory Reconsolidation by Propranolol : a Multisite Trial
The purpose of this study is to test whether propranolol, when given during a re-evocation of a traumatic memory, is capable of reducing subsequent PTSD symptoms associated with that memory.
- Trial name
- REDUCTRAUMA2 (NCT01713556)
- Testing
- Propranolol, Trauma reactivation
- Where
- 4 sites in France
- Volunteers
- 87 people
- Sponsor
- University Hospital, Toulouse
PTSD, Alcohol Use Disorder
MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress Disorder
To explore the effectiveness of of MDMA-assisted prolonged exposure therapy in improving treatment outcomes for individuals with comorbid PTSD and alcohol use disorder in a double-blind randomised placebo-controlled trial.
- Conditions
- PTSD, Alcohol Use Disorder, Alcohol Dependence, Post-traumatic Stress Disorder
- Trial name
- MPATHY (NCT05709353)
- Testing
- Prolonged exposure therapy, MDMA, Niacin
- Where
- 2 sites in Australia
- Volunteers
- 120 people
- Sponsor
- University of Sydney
Physical Disability, Depression
Prognostication of Need for Rehabilitation and Special Support in ICU Survivors
Title: PROGnostication of need for REhabilitation and Special Support after Intensive Care Unit Stay - a multinational, observational study Objectives: 1.
- Conditions
- Physical Disability, Depression, Posttraumatic Stress Disorder, Anxiety
- Trial name
- PROGRESS-ICU (NCT02679157)
- Where
- 10 sites in Denmark, Netherlands and 1 more
- Volunteers
- 573 people
- Sponsor
- Karolinska University Hospital
PTSD
Pilot-Study DCPT for PTSD in Adolescents and Young Adults
The aim of this pilot study is to evaluate the developmentally adapted cognitive processing therapy (D-CPT)in adolescents suffering from childhood abuse(CA)or physical abuse (PA) related PTSD.
- Trial name
- Pilot-DCPT (NCT01870271)
- Testing
- Developmentally adapted cognitive processing therapy
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Goethe University
Posttraumatic Stress Disorder, Cannabis Use Disorder
Mitigating PTSD-CUD After Sexual Assault
683,000 women are sexually assaulted annually in the United States, half of whom develop chronic posttraumatic stress disorder (PTSD) and thus have markedly increased risk for cannabis use disorder (CUD).
- Trial name
- RISE-C (NCT05989841)
- Testing
- RISE Guide, Relaxation Control
- Where
- 6 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Nevada, Las Vegas
Post-traumatic Stress Disorder
Program for Alleviating and Resolving Trauma and Stress 1
This single-arm pilot study (Phase 1) will test the preliminary efficacy of a virtually delivered, live-online 16-week group model of Internal Family Systems (IFS) for individuals with PTSD, called the PARTS program, on PTSD…
- Trial name
- PARTS1 (NCT04713501)
- Testing
- PARTS Program
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Posttraumatic Stress Disorder
A Dose Escalation Study of Intranasal Neuropeptide Y in Post Traumatic Stress Disorder (PTSD)
This study is designed to investigate the safety of intranasal administration of NPY using a dose escalation, randomized, double-blinded, placebo-controlled crossover design in a medication-free, symptomatic PTSD group.
- Trial name
- NCT01533519
- Testing
- Neuropeptide Y
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- James Murrough
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