Clinical trials: Stress Disorder, Post-Traumatic
Mild Traumatic Brain Injury, Posttraumatic Stress Disorder
Improving Cognitive Rehabilitation Outcomes
Posttraumatic stress disorder (PTSD) and mild TBI (mTBI) frequently co-occur in post-9/11 Veterans, and together are associated with worse cognitive performance, mental health, everyday functioning, community integration, quality…
- Trial name
- NCT07055633
- Testing
- CCT+MBLT, CCT+ION
- Where
- 2 sites in United States
- Volunteers
- 144 people
- Sponsor
- VA Office of Research and Development
PTSD
Maintenance Phase Treatment With Divalproex for Post Traumatic Stress Disorder
The primary objective is to evaluate the long-term efficacy of divalproex sodium (Depakote) in the continuation treatment of PTSD.
- Trial name
- NCT00203385
- Testing
- Divalproex
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Tuscaloosa Research & Education Advancement Corporation
Posttraumatic Stress Disorder
Family Involvement in Treatment for PTSD
Post-traumatic stress disorder (PTSD), prevalent among returning OEF/OIF/OND Veterans, has a powerful impact on family functioning.
- Trial name
- NCT00893152
- Where
- 2 sites in United States
- Volunteers
- 83 people
- Sponsor
- US Department of Veterans Affairs
Childhood Trauma, Stress
Psychosocial Correlates of Trait Emotional Intelligence and Psychosomatic Symptoms Among Adolescents Exposed to Bullying and the Effects of Mindfulness-Based Stress Reduction.
This study examines the psychosocial correlates of trait emotional intelligence and psychosomatic symptoms among adolescents exposed to bullying and analyzes the effetiveness of Mindfulness Based Stress Reduction (MBSR) program…
- Conditions
- Childhood Trauma, Stress, Emotional Intelligence, Psychosomatic Disorders
- Trial name
- MBSR-RCT (NCT07694908)
- Testing
- Mindfulness Based Stress Reduction (MBSR)
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Fatima Jinnah Women University
Post Traumatic Stress Disorder
Brexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSD
This will be a 12-week, multicenter, randomized, double-blind trial evaluating the efficacy, safety, and tolerability of brexpiprazole + sertraline combination treatment in adult participants with Post-Traumatic Stress Disorder.
- Trial name
- NCT04124614
- Testing
- Brexpiprazole, Sertraline
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Cervicogenic Headache, Sleep Disturbance
Effect of Isometric Neck Exercises on Cervicogenic Headache Symptoms, Cortisol and BDNF Levels Among Smart Phone Users
Cervicogenic headache (CGH) is a secondary headache type caused due to refereed pain arising from the cervical spine in the forehead, sometimes in temporal region.
- Conditions
- Cervicogenic Headache, Sleep Disturbance, Stress
- Trial name
- NCT07354776
- Testing
- Isometric Neck Exercise Program, Usual Care
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Stress Disorders, Post-Traumatic, Anxiety
Treating Post Traumatic Stress Disorder in Children Exposed to Domestic Violence
This study will determine whether trauma-focused cognitive behavioral therapy (TF-CBT) is more effective than child-centered therapy (CCT) in reducing post traumatic stress disorder (PTSD) in children exposed to domestic violence…
- Conditions
- Stress Disorders, Post-Traumatic, Anxiety, Depression
- Trial name
- NCT00183326
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT), Child-centered supportive therapy (CCT)
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Childbirth-related Post-traumatic Stress Disorder
Assessment of Childbirth-Related Post-Traumatic Stress Disorder
The main objective of this study is to estimate the prevalence of childbirth-related post-traumatic stress disorder (PTSD) among mothers treated at the maternity ward of Emile Muller Hospital (Mulhouse, Haut-Rhin, France).
- Trial name
- SSPT-A (NCT07827508)
- Testing
- City Birth Trauma Scale and Questionnaire on the assessment of healthcare utilization
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Self Harm, Personality Disorders
Extreme Challenges - Psychopathology & Treatment Experiences Among Severly Selfharming Inpatients in Norway
Patients who self-harm are a heterogeneous population. Outpatient treatments structured for borderline personality disorder are often recommended and hospitalization kept to a minimum.
- Conditions
- Self Harm, Personality Disorders, Psychosis, Developmental Disorder
- Trial name
- NCT03768674
- Testing
- Assessment of diagnoses, functioning and health services
- Where
- Norway
- Volunteers
- 1,640 people
- Sponsor
- Oslo University Hospital
Stress Disorders, Post-Traumatic, Substance Use Disorders
Massed Prolonged Exposure for PTSD in Substance Use Treatment
The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week among veterans with PTSD and…
- Trial name
- PREVAIL (NCT06296186)
- Testing
- Prolonged Exposure Therapy
- Where
- 6 sites in United States
- Volunteers
- 200 people
- Sponsor
- Veterans Medical Research Foundation
Post-Traumatic Stress Disorder
Prolonged Exposure Therapy Versus Active Psychotherapy in Treating Post-Traumatic Stress Disorder in Adolescents
This study will compare the effectiveness of prolonged exposure therapy versus active psychotherapy in treating post-traumatic stress disorder (PTSD) in adolescents.
- Trial name
- NCT00183690
- Testing
- Prolonged Exposure Therapy, Active Psychotherapy
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Posttraumatic Stress Disorder
Compassion Meditation for PTSD
The goal of this project is to refine an existing compassion meditation protocol for individuals with posttraumatic stress disorder (PTSD), to examine the safety and feasibility of this approach and to collect data to make…
- Trial name
- NCT02372396
- Testing
- Compassion Meditation (CM), Relaxation
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Veterans Medical Research Foundation
Posttraumatic Stress Disorder, Depression
Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study
Posttraumatic stress disorder (PTSD) can have significant impairment on aspects of mental well-being (MWB) including functioning, loneliness, physical health, and quality of life.
- Trial name
- NCT07250061
- Testing
- Self-Help Cognitive Processing Therapy, Women Veterans Network (WoVeN), Treatment as Usual
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston University
Severe Trauma
Emotional and Social Impact on the Relatives of Hospitalized Children for Severe Trauma
This research aims to study the occurrence of post-traumatic stress, anxiety or depression in the parents of a child who has been hospitalized in intensive care unit following a severe trauma.
- Trial name
- RESPET (NCT04168827)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocardial Infarction
Anxiety, Stress and Pain & Myocardial Infarction
People often experience the acute phase of a myocardial infarction as a stressful and traumatic event that seems lifethreatening.
- Trial name
- NCT04130269
- Testing
- No intervention
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
PTSD, Complex Post-Traumatic Stress Disorder
8-day Intensive Treatment Programme for PTSD and CPTSD in Sweden
Post-Traumatic Stress Disorder (PTSD) and Complex PTSD (C-PTSD) are conditions that may develop after a person has been exposed to extremely stressful experiences.
- Trial name
- 8-day ITP (NCT06645028)
- Testing
- Intensive treatment programme, Treatment as Usual (TAU)
- Where
- Sweden
- Volunteers
- 118 people
- Sponsor
- Christina Blomdahl
Posttraumatic Stress Disorder (PTSD), Intrinsic and Novelty-related Sensory Cortical (SC) Disinhibition
A Neurosensory Account of Anxiety and Stress (Study 1)
This study will take a basic neuroscience approach to investigate pathological mechanisms underlying PTSD. Additionally, the study aims to identify how Transcranial Alternating Current Stimulation (tACS) brain stimulation can…
- Trial name
- NCT05895006
- Testing
- Alternating Current Stimulation (tACS), Transcranial Random Noise stimulation (tRNS)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Posttraumatic Stress Disorder
Targeted Strategies to Accelerate Evidence-Based Psychotherapy (EBP) Implementation in Military Settings
This study will evaluate a program designed to increase military treatment facilities' use of Prolonged Exposure (PE), an evidence-based psychotherapy for PTSD.
- Trial name
- NCT03663452
- Testing
- Targeted Assessment and Context-Tailored Implementation of Change Strategies (TACTICS), Prolonged exposure training
- Where
- 8 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Borderline Personality Disorder, Posttraumatic Stress Disorder
FKBP5 Methylation and Childhood Emotional Abuse in Complex Posttraumatic Stress Disorder: Investigating the Relationship and Its Predictive Role in Therapy Outcome
The aim of this study is to investigate the role FKBP5 DNA methylation levels in patients suffering from complex posttraumatic stress disorder, who participated in a 12-weeks disorder-specific DBT-PTSD inpatient treatment.
- Trial name
- NCT06433843
- Testing
- Dialectical behavioral therapy for the treatment of posttraumatic stress disorder (DBT-PTSD)
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- University Hospital Tuebingen
PTSD, Substance Use Disorders
Alcohol Use Disorders (AUDs) and Post-traumatic Stress Disorder (PTSD) Treatment for Victims of Partner Violence
The goal of this study is to evaluate a psychotherapy for PTSD and substance use disorders among women who have experienced domestic violence.
- Trial name
- NCT00607412
- Testing
- Integrated psychotherapy for PTSD and substance use, 12-step based supportive therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
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