Clinical trials: Stress Disorder, Post-Traumatic
PTSD, Alcohol Use Disorder
Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees
The goal of this clinical trial is to determine if a peer-delivered emotion regulation training (Brief-Unified Protocol) workshop is effective for preventing posttraumatic stress and other psychological health symptoms in…
- Conditions
- PTSD, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- PEER UP (NCT06290778)
- Testing
- Brief Unified Protocol, Psychoeducation
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Post-Traumatic Stress Disorder
Enhancing Equitable and Effective (E-3) Post Traumatic Stress Disorder (PTSD) Disability Assessment
This project evaluated the impact of semi-structured, standardized interviews on the initial PTSD C\&P on the examination.
- Trial name
- E-3PTSD (NCT00699660)
- Testing
- CAPS/WHODAS, Nonstructured Interview
- Where
- 11 sites in United States
- Volunteers
- 406 people
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder (PTSD)
PTSD Risk Prediction Model for EICU Survivors
Brief Title: PTSD Risk Prediction Model for EICU Survivors Official Title: Development and Validation of a Risk Prediction Model for Post-Discharge Post-Traumatic Stress Disorder in Emergency Department-Admitted EICU Survivors…
- Trial name
- NCT07747415
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Sir Run Run Shaw Hospital
Mental Health Issue, Anxiety Disorders
Delivering ICBT to Address Mental Health Challenges in Correctional Officers and Other Public Safety Personnel
Public safety personnel (PSP) have regular and often intense exposure to potentially traumatic events at work and are at higher risk for developing mental health problems such as posttraumatic stress disorder (PTSD).
- Conditions
- Mental Health Issue, Anxiety Disorders, Depressive Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT04666974
- Testing
- iCBT, In-Person CBT
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Dr. Nazanin Alavi
Depression, Depressive Disorder, Treatment-Resistant
Improving Brain Stimulation Through Imaging
There are two protocols, one involving rTMS therapy in people with treatment resistant depression and one involving tDCS in people with stress from the COVID 19 pandemic.
- Conditions
- Depression, Depressive Disorder, Treatment-Resistant, COVID Stress, PTSD - Post Traumatic Stress Disorder
- Trial name
- IBSI (NCT03851380)
- Testing
- Psychological / Functional Assessment, Structural and Functional MRI, Transcranial Magnetic Brain Stimulation and MR Image Guidance
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder, PTSD
Brexpiprazole as an Adjunctive Treatment to Paroxetine or Sertraline in Adult Patients Suffering From Post-traumatic Stress Disorder (PTSD)
To evaluate the efficacy of brexpiprazole as adjunctive treatment to paroxetine (PAR) or sertraline (SER) on PTSD symptoms.
- Trial name
- NCT01987960
- Testing
- Brexpiprazole
- Where
- 59 sites in United States, Estonia and 7 more
- Volunteers
- 417 people
- Sponsor
- H. Lundbeck A/S
Major Depressive Disorder, Dysthymic Disorder
Quetiapine in Co-Morbid Depressive and Anxiety Disorders
This multi-centred study will be conducted at three centres. The design will be a randomized, placebo-controlled, parallel-group one.
- Conditions
- Major Depressive Disorder, Dysthymic Disorder, Anxiety Disorders, Generalized Anxiety Disorder
- Trial name
- NCT00688818
- Testing
- Quetiapine
- Where
- 4 sites in Canada
- Volunteers
- 108 people
- Sponsor
- Centre for Addiction and Mental Health
PTSD, Sexual Abuse
PTSD and Risk Behavior in HIV Positive Female Adolescents
This is a qualitative study using a purposive sampling methodology to interview HIV-positive female adolescents who have experienced physical and/or sexual abuse.
- Conditions
- PTSD, Sexual Abuse, HIV Infections
- Trial name
- NCT00271882
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Suicidal Ideation, Suicide, Attempted
Improving Treatment Outcomes for Suicidal Veterans With PTSD
The efficacy of cognitive processing therapy (CPT) for reducing the symptoms of posttraumatic stress disorder (PTSD) across populations including military personnel and veterans is well supported.
- Conditions
- Suicidal Ideation, Suicide, Attempted, Ptsd
- Trial name
- NCT04690582
- Testing
- Cognitive Processing Therapy (CPT), Crisis Response Plan (CRP), Safety Planning Intervention (SPI)
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Ohio State University
Major Depressive Disorder, PTSD
McLean and Genomind Prospective Study
This is a three month naturalistic prospective, randomized, open label study of pharmacogenetic testing and clinical outcomes in inpatients across diagnoses, including Treatment Resistant Depression (TRD) with or without…
- Trial name
- GPS (NCT03113890)
- Testing
- Phlebotomy - Folate, Cheek Swab, Self-report surveys
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Mclean Hospital
Post Traumatic Stress Disorder, Cannabis Use
Warrior CARE: Cannabis Behavioral Health
This study is a randomized, controlled clinical trial to examine the therapeutic potential of cannabinoids for treating veterans with PTSD and suicidal ideation.
- Conditions
- Post Traumatic Stress Disorder, Cannabis Use, Suicide, Veterans
- Trial name
- CBH (NCT06381180)
- Testing
- Tetrahydrocannabinol, Cannabidiol
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Wayne State University
Post-Traumatic Stress Disorder (PTSD), Depressive Symptoms
Trauma-Focused Cognitive Behavioral Therapy in Unaccompanied Refugee Minors With PTSD in Greece: An RCT
This single-blinded, multicentered, randomized controlled trial aims to evaluate the effectiveness of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) compared to Treatment-as-Usual (TAU) in reducing post-traumatic stress…
- Conditions
- Post-Traumatic Stress Disorder (PTSD), Depressive Symptoms, Anxiety Symptoms, Somatic Symptoms
- Trial name
- TF-CBT (NCT06975280)
- Testing
- Trauma - Focused Cognitive Behavioral Therapy, Treatment as Usual (TAU)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Theodora Anastasiou
Posttraumatic Stress Disorder
In-Home Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD)
This study examines clinical and process outcomes following variable length prolonged exposure (PE) for posttraumatic stress disorder (PTSD) delivered by one of three treatment modalities: home-based telehealth (HBT)…
- Trial name
- NCT03110302
- Testing
- Prolonged exposure
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Veterans Medical Research Foundation
Dysthymic Disorder
Desvenlafaxine Monotherapy in Dysthymia
This multi-centred study will be conducted at two centres. The design will be an open label, flexible-dose study. This investigation will evaluate the efficacy of Desvenlafaxine monotherapy for patients who meet diagnostic…
- Trial name
- NCT01948895
- Testing
- Desvenlafaxine
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Post Traumatic Stress Disorder (PTSD)
A Clinical Trial for Post Traumatic Stress Disorder
he purpose of this study is to test whether a medication, called mifepristone (commonly known as the ³Morning-After-Pill²), can help to prevent emotional problems after someone has survived a traumatic experience.
- Trial name
- MATTER (NCT00554177)
- Testing
- Medicane (mifepristone)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Antonia New
Panic Disorder, Generalized Anxiety Disorder
Collabri Flex - Effect of Collaborative Care for People With Anxiety Disorders in General Practice
The aim of the study Collabri Flex is to: Develop a Danish model for collaborative care for patients with anxiety in general practice, based on past experience gained in the Collabri Project.
- Conditions
- Panic Disorder, Generalized Anxiety Disorder, Social Phobia, Obsessive-Compulsive Disorder
- Trial name
- NCT03113175
- Testing
- Collaborative care, Consultations-Liaison
- Where
- Denmark
- Volunteers
- 302 people
- Sponsor
- Amager Hospital
Post-traumatic Stress Disorder (PTSD)
Prospective Cohort Study of Accelerated Resolution Therapy (ART) for Treatment of Military Psychological Trauma
This is a prospective cohort treatment intervention study (n=200) whereby U.S. service members and veterans with symptoms of PTSD will undergo 2-5 sessions of ART delivered by Florida licensed mental health professionals trained…
- Trial name
- NCT02030522
- Testing
- Accelerated Resolution Therapy (ART)
- Where
- 8 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Stress Disorders, Post-Traumatic
Implementation of CPT for PTSD in Diverse Communities
Aim: To identify, assess, and address organizational context and provider-level barriers and facilitators of implementation of Evidence-based treatments (EBTs) using a mixed-methods approach in a diverse community mental health…
- Trial name
- NCT01702168
- Testing
- Provider training: Cognitive Processing Therapy (CPT)
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Post Traumatic Stress Disorder
Psycho-traumatic Consequences of the COVID-19 Health Crisis Among Professionals in Emergency Services
The COVID-19 outbreak has been categorized as a pandemic and declared an international public health emergency by WHO. In this context, an exceptional mobilization and a complete reorganization of the organization of the…
- Trial name
- COVER PRO LT (NCT05033223)
- Testing
- PTSD evaluation of emergency room staff 9 and 12 months after the end of second lockdown in France during COvid-19 pandemic
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Hospices Civils de Lyon
Insomnia, Depression - Major Depressive Disorder
Enhancing Operational Readiness With Digital Self-Managed Cognitive Behavioral Therapy for Insomnia (CBTI)
The goal of this pilot clinical trial is to evaluate the effectiveness and delivery method of a CBTI self-managed digital mobile application in service members. The main questions it aims to answer are: RQ1.
- Conditions
- Insomnia, Depression - Major Depressive Disorder, PTSD
- Trial name
- NCT07335276
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Volunteers
- 144 people
- Sponsor
- Madigan Army Medical Center
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