Clinical trials: Stress Disorder, Post-Traumatic
Cardiac Disease, Delirium
A Study to Identify the Incidence of Post Traumatic Stress Symptoms in Patients With Delirium Following Cardiac Surgery
'Post perfusion syndrome' was a term historically associated to cardiac surgery in view of the transient neuro-cognitive deficits attributed to cardio pulmonary bypass pump.
- Conditions
- Cardiac Disease, Delirium, Stress Disorders, Post-Traumatic
- Trial name
- NCT02954861
- Testing
- No intervention
- Volunteers
- 406 people
- Sponsor
- University of Edinburgh
Work Related Stress
Somatic Psychoeducational Intervention
The goal of this clinical trial is to explore possible benefits and mechanisms through which the Somatic Psychoeducational Intervention can improve health and wellness.
- Trial name
- NCT06580119
- Testing
- Somatic Psychoeducational Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
MDD, Bipolar Disorder
Evaluation of Generalization Paradigm Patterns Among Different Psychiatric Disorders
Learning includes the ability to generalize to new situations and respond to similar, yet not identical stimuli. In previous work, focused on stimulus generalization in healthy volunteers, tones that were negatively reinforced…
- Conditions
- MDD, Bipolar Disorder, Schizophrenia Disorder, Anxiety Disorder (Panic Disorder or GAD)
- Trial name
- NCT01501812
- Testing
- Generalization pattern
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Psychologic Manipulation
Cognitive Processing Therapy vs. Sertraline for the Treatment of PTSD & SUD in Egyptian Patients
The present research was aimed at comparing the effects of Cognitive Processing Therapy (CPT) with the effects of Sertraline in treating patients who have dual diagnosis PTSD \& SUD.
- Trial name
- NCT03469128
- Testing
- Cognitive processing therapy, Sertraline
- Volunteers
- 150 people
- Sponsor
- British University In Egypt
Post-traumatic Stress Disorder, Traumatic Brain Injury
Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop
In this proposal, the investigators extend their previous SPiRE feasibility and preliminary effectiveness study to examine STEP-Home efficacy in a RCT design.
- Conditions
- Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression
- Trial name
- STEP-Home (NCT03868930)
- Testing
- STEP-Home, PCGT
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Inflammatory Bowel Diseases, Crohn's Disease
ACT for Veterans With IBD and Mental Health Challenges
Many Veterans with gastrointestinal disorders, such as inflammatory bowel disease (IBD), also have mental health conditions. IBD and mental health conditions can worsen one another through the brain-gut axis, leading to dramatic…
- Conditions
- Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis, Depressive Disorder
- Trial name
- RECLAIM (NCT07397195)
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder, Post Traumatic Stress Disorder
Cannabidiol as a Treatment for AUD Comorbid With PTSD
This project aims to determine whether cannabidiol (CBD), a compound derived from the cannabis plant, is effective in treating alcohol use disorder (AUD) in individuals with comorbid posttraumatic stress disorder (PTSD).
- Trial name
- NCT03248167
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- NYU Langone Health
Posttraumatic Stress Disorders
The Trauma Recovery and Resiliency Research Project
The overall purpose of this study is the assessment of treatment outcome among traumatized patients seeking individual and/or group therapy at the Victims of Violence Program.
- Trial name
- NCT00131534
- Testing
- Individual therapy, Group therapy
- Where
- United States
- Volunteers
- 969 people
- Sponsor
- Cambridge Health Alliance
Acute Stress Reaction, Acute Stress Disorder
BXCL501 After Stress to Increase Recovery Success
This study will examine the safety and efficacy of BXCL501 to reduce ASR symptoms and behavioral changes among patients presenting to the Emergency Department (ED) after Motor Vehicle Collision (MVC).
- Conditions
- Acute Stress Reaction, Acute Stress Disorder, Post-traumatic Stress Disorder
- Trial name
- RISE (NCT06943404)
- Testing
- BXCL501 (dexmedetomidine HCl)
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Borderline Personality Disorder
NEUROIMAGING OF ADOLESCENT BORDERLINE PERSONALITY DISORDER WITH AND WITHOUT POST-TRAUMATIC STRESS DISORDER
Borderline personality disorder (BPD) is a common mental disorder in adolescents with significant individual and societal repercussions, characterized over the long term by emotional hyperresponsiveness, relational instability…
- Trial name
- BorderStress (NCT04852744)
- Testing
- Brain MRI
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Trauma, Psychological, Learning Disability
Narrative Exposure Therapy for Adults With an Intellectual Disability
The goal of this naturalistic single case series design is to investigate if an adapted Narrative Exposure Therapy protocol can be effective, is feasible, and acceptable for adults with a mile learning disability.
- Conditions
- Trauma, Psychological, Learning Disability, PTSD, Intellectual Disability, Mild
- Trial name
- NCT06934109
- Testing
- Narrative Exposure Therapy (NET)
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Nottingham
PTSD
Novel EEG Coherence Biomarkers for PTSD Assessment
Current practice for diagnosing and managing PTSD relies primarily on subjective clinical assessments by clinicians as well as patient self-report.
- Trial name
- NCT04209387
- Testing
- Acceptance and Commitment Therapy to Improve Social Support for Veterans with PTSD ( ACT-SS)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post-Traumatic
Affect Management Group for Adult Survivors of Childhood Trauma
Problems of self regulation, e.g. emotional dysfunction, represent a core symptom of adult patients with traumatic childhood experiences.
- Trial name
- NCT00383006
- Testing
- Skills for affect regulation (behavior)
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- University of Zurich
Unspecified Trauma- and Stressor-Related Disorder
Pulsed ElectroMagnetic Field (PEMF) Therapy in Treating Post-Traumatic Stress Disorder (PTSD) & Trauma
Use of low-voltage, direct current pulsed electromagnetic fields (PEMF) in treating Post Traumatic Stress Disorder (PTSD), complex PTSD (cPTSD) and trauma-related injuries manifesting in physical and/or mental symptoms.
- Trial name
- NCT05033600
- Testing
- S.C.I.O.
- Where
- United Kingdom
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Kasey Phifer
Post Traumatic Stress Disorder
Intensiv Inpatient Trauma Treatment. A Pilotstudy.
Aim of the study: Post traumatic stress disorder (PTSD) is a psychiatric illness that can develop after having experienced traumatic, often life treathening, events.
- Trial name
- ITBD (NCT05342480)
- Testing
- EMDR and PE combined treatment
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Oslo University Hospital
Sex Trafficking, Sexual Violence
Music Workshops in the EMPOWER Clinic
Women will be recruited from the EMPOWER clinic when they present for care; they may be given a flyer as part of their clinic entry paperwork, or approached by a study staff member in the waiting area of the clinic.
- Conditions
- Sex Trafficking, Sexual Violence, Trauma
- Trial name
- NCT02897505
- Testing
- Music Workshop
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Peripheral Vascular Diseases
Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1
The purpose of this research study is to examine the role oxidants, substances produced in the blood that can damage blood vessel function, may play in blood vessel function in healthy individuals as well as individuals with…
- Trial name
- NCT04916327
- Testing
- Antioxidant
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Mental Health, PTSD
Further Development and Initial Testing of RESTORE in Frontline Workers
There is considerable need for psychological intervention targeting stressor-related mental health symptoms related to COVID-19.
- Conditions
- Mental Health, PTSD, Anxiety, Depressive Symptoms
- Trial name
- RESTORE (NCT04873622)
- Testing
- RESTORE: Recovering from Extreme Stressors Through Online Resources and E-health
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Anxiety Disorders, Obsessive-Compulsive Disorder
Relationship Between Repetitive Negative Thinking and CBT Outcomes
The goal of this observational study is to learn about the role of repetitive negative thinking (measured by the RTQ) in adult populations from an anxiety disorders and trauma clinic.
- Conditions
- Anxiety Disorders, Obsessive-Compulsive Disorder, Post-traumatic Stress Disorder, Social Anxiety Disorder
- Trial name
- NCT06370559
- Where
- United Kingdom
- Volunteers
- 320 people
- Sponsor
- South London and Maudsley NHS Foundation Trust
Posttraumatic Stress Disorder
Equine Assisted Activities on PTSD, Quality of Life and Functioning in Veterans With PTSD: An ICF Approach (THRICF)
The purpose of the research project was to assess changes in Posttraumatic stress disorder [PTSD] symptoms, quality of life and participation of combat veteran who participate in equine assisted activities [EAA].
- Trial name
- THRICF (NCT02893202)
- Testing
- Therapeutic Horseback riding
- Volunteers
- 89 people
- Sponsor
- Baylor University
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