Clinical trials: Stress Disorder, Post-Traumatic
PICS, Anxiety
Behavioral Health Collaborative Care Model in an ICU Recovery Clinic
Survivors of critical illness are at high risk for mental health issues such as anxiety, depression, and PTSD. This single-site, randomized controlled trial at the Medical University of South Carolina will enroll 150 patients to…
- Conditions
- PICS, Anxiety, Depression - Major Depressive Disorder, Post-Traumatic Stress
- Trial name
- BeColM (NCT07372586)
- Testing
- Behavioral Health Collaborative Care Model
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Medical University of South Carolina
Posttraumatic Stress Disorder, Insomnia Disorder
Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder
This study will investigate treatments for insomnia in Veterans who have posttraumatic stress disorder (PTSD). The purpose of this study is to compare a brief behavioral treatment for insomnia (BBTI) to a treatment that helps…
- Trial name
- BBTI & PTSD (NCT05780177)
- Testing
- Brief Behavioral Treatment for Insomnia (BBTI), Progressive Muscle Relaxation Training (PMRT)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Well-Being, Psychological, Dissociation
An Adjunctive Neurofeedback Training Program to Enhance Wellness Among Trauma-Exposed Postpartum Mothers
The proposed study will collect novel data evaluating the feasibility of the NFB training program delivered in an outpatient mental health setting and its influence on mothers' overall sense of well-being, and further investigate…
- Conditions
- Well-Being, Psychological, Dissociation, Maternal Care Patterns, Maternal Behavior
- Trial name
- NCT06054412
- Testing
- Neuroptimal (Zengar, Inc.) Neurofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wayne State University
Stress Disorders, Post-Traumatic
Improving Mind/Body Health and Functioning With Integrative Exercise
There is evidence demonstrating that aerobic exercise improves many symptoms of Posttraumatic Stress Disorder (PTSD) including; anxiety, depression, insomnia, and cognition.
- Trial name
- NCT02856412
- Testing
- Veterans Group Exercise (VGX), Illness Management and Recovery
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- VA Office of Research and Development
Professional Burnout, Moral Injury
Professional Contributions and Social Value in High-Acuity Medical Care Settings
This study will explore experiences in high-acuity medical care settings, such as emergency, trauma, intensive care, and related clinical areas.
- Trial name
- NCT07686666
- Testing
- Experience in high-acuity clinical care settings
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Insomnia, Nightmares Associated With Trauma and Stress
Restorative Early Sleep Treatment After the Emergency Department
The goal of this randomized controlled trial is to pilot the virtual delivery of cognitive behavioral therapy for insomnia (CBT-I) and nightmares (CBT-I\&N) via telehealth as an early intervention for treating posttraumatic sleep…
- Conditions
- Insomnia, Nightmares Associated With Trauma and Stress, Nightmares, PTSD - Post Traumatic Stress Disorder
- Trial name
- RESTED (NCT07121270)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia and Nightmares, Sleep Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Henry Ford Health System
Trauma, Post-Traumatic Stress Disorder
Helping Children With Trauma
The purpose of this study is to evaluate if a trauma treatment called Trauma Systems Therapy (TST) decreases children's mental health symptoms (such as acting out, not controlling their emotions, etc.) as a result of a traumatic…
- Trial name
- NCT02737488
- Testing
- Trauma Systems Therapy (TST), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- NYU Langone Health
Posttraumatic Stress Disorders
Cognitive Behavioral Therapy to Improve Work and Wellness in Veterans With Mental Illness
Vocational instability in Veterans with serious mental illness (SMI) is pervasive, costly, and harmful. Over 75% of Veterans with SMI are unemployed, resulting in economic difficulties and trouble meeting basic needs.
- Trial name
- WORKWELL (NCT04504903)
- Testing
- Cognitive Behavioral Therapy For Work Success (CBTw), Psychoeducation
- Where
- 3 sites in United States
- Volunteers
- 294 people
- Sponsor
- VA Office of Research and Development
PTSD
Using Heart Rate Variability Biofeedback to Improve Attention and Memory in PTSD+ Combat Veterans
This study will test the effectiveness of Heart Rate Variability (HRV) Biofeedback as a therapeutic tool in the reduction of everyday memory problems routinely experienced by combat veterans with Posttraumatic Stress Disorder…
- Trial name
- HRVB (NCT00625105)
- Testing
- Biofeedback
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- William Jennings Bryan Dorn VA Medical Center
PTSD
Aripiprazole Augmentation of Antidepressants in PTSD
The proposed investigation will determine the therapeutic potential of aripiprazole augmentation to a stable antidepressant regimen for reducing posttraumatic stress disorder (PTSD) symptoms, cognitive symptoms, psychotic…
- Trial name
- NCT00489866
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Durham VA Medical Center
Post Traumatic Stress Disorder
An Internet-delivered Cognitive-behavioral Intervention Provided Soon After Trauma: a RCT
The primary objective with this study is to investigate the short-term efficacy (primary endpoint at week 3) of Internet-delivered cognitive behavior therapy (ICBT) provided soon after trauma.
- Trial name
- NCT04101942
- Testing
- Internet-based CBT
- Where
- Sweden
- Volunteers
- 38 people
- Sponsor
- Karolinska Institutet
Post-Concussion Syndrome, Concussion, Brain
Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
The goal of this study is to investigate a new treatment for chronic symptoms after concussion or mild traumatic brain injury in people aged 18-65 years old.
- Conditions
- Post-Concussion Syndrome, Concussion, Brain, Mild Traumatic Brain Injury, Head Injury
- Trial name
- NCT06073886
- Testing
- Active cTBS, Imaginal exposure
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Los Angeles
Combat Posttraumatic Stess Disorder, Mild Traumatic Brain Injury
Lithium Augmentation for Hyperarousal Symptoms of Post Traumatic Stress Disorder: Pilot Study
The purpose of this study is to explore the effectiveness of adding lithium carbonate (lithium) to treatment for combat-related post traumatic stress disorder in combat veterans.
- Trial name
- NCT01754883
- Testing
- Lithium Carbonate
- Where
- United States
- Sponsor
- VA Eastern Colorado Health Care System
Posttraumatic Stress Disorder, Depression
Mindfulness Meditation Format Pilot Study
The purpose of this study is to assess feasibility of an internet and individual format of mindfulness meditation in people with posttraumatic stress disorder (PTSD) and depression symptoms
- Trial name
- NCT01581983
- Testing
- Internet Mindfulness Meditation, Individual Mindfulness Meditation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Oregon Health and Science University
Anxiety, Depression
Impact of Information Strategy Based on Booklet on Anxiety in Family in ICU
Anxiety and depression are symptoms frequently met in ICU patients and relatives. Risk factors are known: disease severity, age, gender. Another risk factor is lack of information from the medical staff and nurses.
- Conditions
- Anxiety, Depression, Post-traumatic Stress Disorders
- Trial name
- FAMILLE (NCT01365377)
- Testing
- booklet deliverance and use in the process of daily information
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Posttraumatic Stress Disorder, Anxiety Disorders
Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety
The goal of this clinical trial is to compare two different intensive formats of delivering cognitive-behavioral treatment for people with PTSD and anxiety disorders.
- Trial name
- NCT05843695
- Testing
- iTCBT-I, iTCBT-G, TAU
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- Baylor College of Medicine
PTSD
Supported Education Pilot
The goal of this project is to gather data necessary for a full scale trial of a supported education service for OIF/OEF veterans with PTSD.
- Trial name
- SEd (NCT01073657)
- Testing
- Supported Education, General Peer Support
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Posttraumatic Stress Disorder
A Case Formulation Approach to Cognitive Processing Therapy
Recent estimates suggest that over 610,000 US Veterans treated by the Veterans Health Administration (VHA) suffer from PTSD, a disorder that can be chronic and debilitating.
- Trial name
- CF-CPT (NCT04407767)
- Testing
- Case Formulation plus Cognitive Processing Therapy, Cognitive Processing Therapy
- Where
- 8 sites in United States
- Volunteers
- 194 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder (PTSD), Sleep Disturbances and Insomnia
A Study to Evaluate Effects on Sleep and Safety of RE03 in PTSD Patients With Sleep Disturbances
Post-traumatic stress disorder (PTSD) affects many people who have experienced traumatic events. A common issue with PTSD is severe sleep disturbances, such as nightmares.
- Trial name
- PTSD-PoC (NCT06685965)
- Testing
- RE03
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Reconnect Labs
FM and PTSD
Neurohormonal Benefits of Exercise in Fibromyalgia and PTSD
The most recent conflicts are creating a new generation of Veterans, including an increasing number of women Veterans, who present with comorbid PTSD and chronic pain conditions, including Fibromyalgia (FM), from…
- Trial name
- EXFMPTSD (NCT03236467)
- Testing
- Progressive Exercise Training
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
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