Clinical trials: Stress Disorder, Post-Traumatic
Posttraumatic Stress Disorder
Neurosteroids in PTSD - Biomarkers to Therapeutics
The purpose of this research is to determine if a study medication called Dehydroepiandrosterone (DHEA) helps to reduce PTSD symptoms in OEF/OIF/OND Veterans.
- Trial name
- NCT03491007
- Testing
- DHEA
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
PTSD
Glecaprevir/Pibrentasvir for the Treatment of PTSD
An open-label pilot study to further investigate glecaprevir/pibrentasvir (GLE/PIB), a direct acting antiviral (DAA) that has been associated with posttraumatic stress disorder (PTSD) symptom improvement when prescribed for the…
- Trial name
- NCT05446857
- Testing
- Glecaprevir / Pibrentasvir Pill
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- White River Junction Veterans Affairs Medical Center
Trauma, PTSD
The Development and Evaluation of a Brief CFT Intervention for Trauma
PLEASE NOTE this study is currently open only to clients on the waiting list at the Centre for Trauma Resilience and Growth, UK.
- Trial name
- NCT02413307
- Testing
- Compassion Focused Therapy (self-practice)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Lincoln
Intimate Partner Violence
Telephone Intervention to Increase Safety in Abused Women
Although abuse by an intimate partner is very common and has serious negative effects on women's health, few studies have been done to test ways to increase safety for women in abusive relationships.
- Trial name
- NCT00457522
- Testing
- Nurse/community health worker telephone intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Chronic Fatigue Syndrome, Fibromyalgia
Compare the Medical Conditions of Gulf War Veterans to Non-Deployed Veterans
Primary Hypothesis: Gulf War veterans will have an equal prevalence or mean level of the following medical and psychological conditions frequently reported in the literature compared to a control group of nondeployed veterans…
- Conditions
- Chronic Fatigue Syndrome, Fibromyalgia, Post-Traumatic Stress Disorder, Neurologic Abnormalities
- Trial name
- NCT00032461
- Volunteers
- 2,000 people
- Sponsor
- US Department of Veterans Affairs
PTSD - Post Traumatic Stress Disorder, Intrusive Memories of Traumatic Event(s)
Neuromodulation of the Hippocampus to Reduce Intrusive Re-Experiencing in PTSD: A Randomized Controlled Trial
The goal of this clinical trial is to learn if non-invasive neurostimulation of memory-related brain areas works to treat intrusive memory symptoms in adults patients with posttraumatic stress disorder (PTSD).
- Trial name
- NCT06639061
- Testing
- Hippocampal stimulation using repetitive transcranial magnetic stimulation (rTMS)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
Disaster, PTSD
Feasibility and Efficacy of a Digital Mental Health Intervention for Teen Wildfire Survivors
In October, 2017, Northern California experienced devastating and historic wildfires. Sonoma Rises is an app designed for anyone who was impacted by this event and is intended to help survivors of disaster find their new normal.
- Conditions
- Disaster, PTSD, Adolescent Behavior, Trauma
- Trial name
- NCT03868761
- Testing
- Sonoma Rises
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Stanford University
PTSD
The Influence of Aerobic Exercise on Consolidation of Fear Extinction Learning in PTSD
This study aims to test whether aerobic exercise performed after fear extinction learning improves cognitive, physiological, and neural indices of extinction recall in a sample of trauma-exposed men and women with and without…
- Trial name
- NCT06144203
- Testing
- Exercise
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Posttraumatic Stress Disorder
Implementation of Evidence-based Psychotherapy for PTSD
Approximately 9% of Canadians will have Posttraumatic Stress Disorder (PTSD) in their lifetime. In the military veteran population, the lifetime prevalence of PTSD has been estimated to be as high as 20%.
- Trial name
- NCT01861769
- Testing
- Technology-enhanced Teleconsultation, Standard Teleconsultation
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Toronto Metropolitan University
Stress Disorders, Post-Traumatic
Effect of Emotional Freedom Technique and Diaphragmatic Breathing on Post Traumatic Stress Disorder (PTSD)
A great many soldiers are returning from Iraq and Afghanistan with symptoms of Post Traumatic Stress Disorder (PTSD). Clinical experience with many people has shown the effectiveness of the techniques of Energy Psychology for…
- Trial name
- NCT00514956
- Testing
- Emotional Freedom Techniques (EFT)
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Soul Medicine Institute
Brain Injury Traumatic Mild, Post-traumatic Stress Disorder
Brain Health & Wellness Classes for Veterans With Traumatic Brain Injury
This study is testing the usefulness of two types of Brain Health \& Wellness classes for Veterans with a history of concussion to improve mental health.
- Trial name
- NCT06150196
- Testing
- Mindfulness-based Stress Reduction class, Brain Health Education class
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- East Bay Institute for Research and Education
Stress, Post Traumatic Stress Disorder
AWARENESS Trial (AWARENESS) of Storytelling Through Music in Healthcare Workers
This research study is examining the feasibility and effectiveness of an online version of the Storytelling Through Music (STM) program with oncology nurses who have worked during the COVID-19 pandemic.
- Conditions
- Stress, Post Traumatic Stress Disorder, Work Related Stress
- Trial name
- NCT04775524
- Testing
- Storytelling Through Music (STM), Wait List / Storytelling Through Music-Hybrid
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Dana-Farber Cancer Institute
PTSD, Traumatic Brain Injury
Psychological Treatment for Children Suffering From Post Traumatic Stress Symptoms and Mild Traumatic Brain Injury
The purpose of this study is to determine whether Prolonged Exposure Therapy (PE)is effective in the treatment of post-traumatic stress symptoms in children and adolescents with mild traumatic brain injury (m-TBI) due to motor…
- Conditions
- PTSD, Traumatic Brain Injury, Post Concussive Syndrome
- Trial name
- TBI (NCT01315379)
- Testing
- Prolonged Exposure Therapy
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Sexual Risk Behavior, Childhood Sexual Abuse
HIV Prevention and Trauma Treatment for Men Who Have Sex With Men With Childhood Sexual Abuse Histories
Brief Summary: The specific aims of this study are: 1. To test, in a two-arm randomized controlled trial, the efficacy of cognitive processing therapy for sexual risk and posttraumatic symptom severity reduction (CPT-SR) in…
- Conditions
- Sexual Risk Behavior, Childhood Sexual Abuse, Stress Disorders, Post-Traumatic
- Trial name
- THRIVE (NCT01395979)
- Testing
- Cognitive Processing Therapy for Sexual Risk, Supportive Psychotherapy, Sexual Risk Reduction Intervention
- Where
- 3 sites in United States
- Volunteers
- 232 people
- Sponsor
- Massachusetts General Hospital
Stroke, Stress, Psychological
Stroke Rehabilitation Utilizing Therapeutical Methods Designed for Nature Environments
Outpatient participants with a recent stroke diagnoses receive complimentary rehabilitation. The nature interventions include ergo- and physiotherapeutic and neurocognitive tasks with the support of an psychotherapeutic frame…
- Conditions
- Stroke, Stress, Psychological, Post Traumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT06633146
- Testing
- Therapies in nature
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Depressive Disorder
Study to Evaluate the Safety and Efficacy of PEER Interactive Versus Treatment as Usual in Subjects With a Primary Diagnosis of Depression
This is a prospective, multicenter, randomized, double-blind, controlled study to evaluate the effectiveness of PEER Interactive to inform treatment in subjects with a primary diagnosis of depression with comorbidity of…
- Trial name
- NCT01794559
- Testing
- PEER Interactive Report
- Where
- 2 sites in United States
- Volunteers
- 1,922 people
- Sponsor
- MYnd Analytics
Post Traumatic Stress Disorder
Sleep and Emotion Processing in Adolescent Post-traumatic Stress Disorder
The goal of this clinical trial is to characterize the role of sleep, emotion processing, and daily affect in post-traumatic stress disorder (PTSD) and whether improving sleep quality using slow wave activity enhancement will…
- Trial name
- NCT06341413
- Testing
- SmartSleep device
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Burn-Out Syndrome, Work-Related Stress Disorder
A Mindfulness Based Cognitive Therapy (MBCT) Resiliency Program for Critical Care Nurses
Developed over 10 years ago, Mindfulness Based Cognitive Therapy (MBCT) synergistically combines mindfulness training and cognitive behavioral therapy and can increase resiliency.
- Trial name
- NCT03132220
- Testing
- Mindfulness-Based Cognitive Therapy, Book Club Active Control Intervention
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Stress Disorders, Post-Traumatic
Examining the Role of Negative Emotional States on Sedative Drug Use in Individuals With Post-Traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a serious illness, in which individuals often experience anxiety and stress. Some individuals with PTSD use drugs to alleviate emotional distress.
- Trial name
- NCT00244335
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Moral Injury
Comparing Two Moral Injury Treatments
Purpose of this study: The purpose of this study is to evaluate the effectiveness of two psychological treatments for moral injury: Acceptance and Commitment Therapy for Moral Injury and Present Centered Therapy for Moral Injury.
- Trial name
- NCT07710521
- Testing
- Acceptance and Commitment Therapy for Moral Injury (ACT-MI), Present Centered Therapy for Moral Injury (PCT-MI)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- VA Eastern Colorado Health Care System
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