Clinical trials: Stress Disorder, Post-Traumatic
PTSD, CBT
Blended Treatment för PTSD: A New Format of Computer-Assisted Trauma-Focused Cognitive Behavioral Therapy
A Randomized Controlled Non-inferiority Trial testing if the new experimental Blended Trauma focused cognitive behavioral therapy (B-TF-CBT) for post traumatic stress disorder (PTSD), is non-inferior to gold standard control…
- Trial name
- NCT05758987
- Testing
- Blended Trauma focused Cognitive Behavioral Therapy (B-Tf-CBT), Prolonged exposure
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Karolinska Institutet
Endometrium Cancer, Post Traumatic Stress Symptoms
Effect of Motivational Interviewing on Posttraumatic Stress Symptoms and Posttraumatic Growth in Women with Endometrial Cancer
Cancer is still the second leading cause of death worldwide with approximately 9.6 million deaths per year. Gynecological cancers, which are the most common type of cancer among women, significantly affect the quality of life by…
- Conditions
- Endometrium Cancer, Post Traumatic Stress Symptoms, Post Traumatic Growth, Psychological
- Trial name
- NCT06781216
- Testing
- Motivational interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Akdeniz University
PTSD, Rape Sexual Assault
RRT for PTSD Symptoms in Survivors of Sexual Violence
Study to provide evidence of efficacy for Rapid Resolution Therapy in symptoms of PTSD, Anxiety, and Depression in survivors of sexual violence.
- Trial name
- NCT04073004
- Testing
- Rapid Resolution Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Anxiety
Exercise in Anxiety and Posttraumatic Stress Disorders
Aim: Aerobic and resistance exercise showed anxiolytic effects in clinical populations. Climbing could further enhance self-efficacy.
- Trial name
- NCT03758599
- Testing
- Climbing, Nordic Walking, Social Contact
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Universitaet Innsbruck
Stress Disorders, Post-Traumatic, Shame
Healthy Recovery After Trauma Study
Mental contamination-an internal experience of dirtiness evoked in the absence of physical contact with an external source-has been linked to the development and maintenance of posttraumatic stress disorder (PTSD) following…
- Conditions
- Stress Disorders, Post-Traumatic, Shame, Guilt, Sexual Assault and Rape
- Trial name
- HRT (NCT04585685)
- Testing
- Cognitive Processing Therapy, Self-Compassion Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Christal L Badour
Trauma, Psychological, Moral Injury
Wellness Intervention for Nurses Post Traumatic Growth and Selfcare
Nurses working in home and hospice care settings find their roles emotionally challenging and are at high risk for trauma, strain and fatigue. Such sufferings were high among nurses during the Covid-19 pandemic.
- Conditions
- Trauma, Psychological, Moral Injury, Compassion Fatigue
- Trial name
- WINGS (NCT06674876)
- Testing
- Blog writing
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Purdue University
PTSD
A Pilot Study Of Riluzole In Patients With Post Traumatic Stress Disorder (PTSD)
This open label study will evaluate the safety and efficacy of riluzole in patients with PTSD. Patients will receive riluzole 50mg twice per day orally for 12 weeks as outpatient, with a one month follow up at week 16.
- Trial name
- NCT02019940
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Yale University
PTSD, Stress Disorders, Post - Traumatic
Innovative Delivery of Evidence Based Psychotherapy to Women With Military Sexual Trauma
The purpose of this study is to determine whether a scientifically validated treatment for Posttraumatic Stress Disorder (PTSD) called Prolonged Exposure (PE) can be delivered effectively to Veterans with Military Sexual Trauma…
- Conditions
- PTSD, Stress Disorders, Post - Traumatic, Anxiety Disorders, Mental Disorders
- Trial name
- NCT02417025
- Testing
- PE
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Medical University of South Carolina
Physical Activity, PTSD
Tai Chi and Wellness Education for Older Veterans
The primary purpose of this study is to examine physical fitness, PTSD, and satisfaction with a Tai Chi intervention for older (aged 60 and older), sedentary, trauma-exposed veterans, in comparison to a wellness education…
- Conditions
- Physical Activity, PTSD, Satisfaction
- Trial name
- NCT03624868
- Testing
- Tai Chi, Wellness Education
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- VA Boston Healthcare System
Posttraumatic Stress Disorder, Substance Use Disorders
Written Exposure in Substance Treatment
The purpose of this pilot randomized clinical trial is to test the feasibility and efficacy of written exposure therapy (WET) for posttraumatic stress disorder (PTSD) within the context of residential substance use disorder (SUD)…
- Trial name
- WEST (NCT06296940)
- Testing
- Written Exposure Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Potomac Health Foundations
Traumatic Brain Injury, PTSD
An Investigation of the Biological and Neuronal Mechanisms of Post Traumatic Stress Disorder, Depression and Post-Concussive Syndrome Onset Following a Traumatic Brain Injury
Background: A traumatic brain injury (TBI) could mean a person is at high risk for other long-lasting problems. These problems could include post-traumatic stress disorder (PTSD), depression, and post-concussive syndrome (PCS).
- Conditions
- Traumatic Brain Injury, PTSD, Depression
- Trial name
- NCT02019654
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- National Institute of Nursing Research (NINR)
Chronic Pain, Traumatic Brain Injury
Neuromodulatory Treatments for Pain Management in TBI
Traumatic brain injury (TBI) and chronic pain are common and serious health problems for military veterans and often co-occur, leading to poor post-deployment adjustment.
- Conditions
- Chronic Pain, Traumatic Brain Injury, Posttraumatic Stress Disorder
- Trial name
- NCT03418129
- Testing
- Mindfulness, Neurofeedback, Relaxation
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- Duke University
Complex Posttraumatic Stress Disorder
PACE Versus PE for CPTSD (PACE Trial)
The objective of this pragmatic trial is to evaluate the beneficial and harmful effects of Patient-centred Modular Cognitive Behavioural Therapy (PACE) compared with the standard post-traumatic stress disorder (PTSD) treatment…
- Trial name
- PACE (NCT07371156)
- Testing
- PACE, PE
- Where
- 10 sites in Denmark
- Volunteers
- 228 people
- Sponsor
- Sofie Folke
Post Traumatic Stress Disorder, Stress Disorders, Post-Traumatic
Reducing Intrusive Memories in Refugees and Asylum Seekers With PTSD
This research study is designed to investigate the use of a simple cognitive task for decreasing the number of intrusive memories of traumatic events experienced by refugees and asylum seekers with a diagnosis of Post-traumatic…
- Conditions
- Post Traumatic Stress Disorder, Stress Disorders, Post-Traumatic, Stress Disorders, Traumatic, Trauma, Psychological
- Trial name
- NCT04394156
- Testing
- Brief cognitive intervention
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- University of Surrey
Posttraumatic Stress Disorder, Substance Use Disorder
Present- Versus Past-focused Therapy for PTSD and Substance Use Disorder
This study compares Creating Change, a new past-focused behavioral therapy for posttraumatic stress disorder (PTSD)/substance use disorder (SUD), to Seeking Safety, an evidence-based present-focused behavioral therapy for…
- Conditions
- Posttraumatic Stress Disorder, Substance Use Disorder, Alcohol Use Disorder
- Trial name
- NCT01274741
- Testing
- Creating Change (CC), Seeking Safety (SS)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- VA Boston Healthcare System
Posttraumatic Stress Disorder, Discriminatory Stress
Writing Wrongs: Expressive Writing for Microaggressions
Racial and ethnic based stressors, such as microaggressions, are pervasive, distressing, and result in lasting negative repercussions for minoritized students at predominantly white institutions (PWIs).
- Conditions
- Posttraumatic Stress Disorder, Discriminatory Stress, Microaggression
- Trial name
- WW (NCT06276725)
- Testing
- Writing Wrongs
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Auburn University
Depression, Stress Disorders, Post-Traumatic
Self-Help Intervention for Post 9/11 Veterans With Depression or PTSD Symptoms
It is important to provide support and resources for the many post-9/11 Veterans with mental health symptoms and poor psychosocial functioning who do not engage in psychotherapy.
- Trial name
- NCT07202325
- Testing
- Resilience Training for Veterans (REST-V), Usual resources
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- VA Office of Research and Development
Spouses, Military Personnel
Spouse READI (Resilience Education And Deployment Information) Post Deployment Telephone Support Groups
This 12-month study is for spouses or significant others of service members who have returned from Afghanistan or Iraq. This study will determine if participating in a telephone discussion group, offering education, skills…
- Conditions
- Spouses, Military Personnel, Coping Skills
- Trial name
- Spouse READI (NCT01121250)
- Testing
- Telephone Discussion Groups, Education sessions
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- Memphis VA Medical Center
Generalized Anxiety Disorder, Agoraphobia
Examining the Effects of Reduced Environmental Stimulation on Anxiety
The studies proposed in this protocol aim to explore the anxiolytic properties of floating as it relates to the central and autonomic nervous system.
- Conditions
- Generalized Anxiety Disorder, Agoraphobia, Panic Disorder, PostTraumatic Stress Disorder
- Trial name
- NCT03051074
- Testing
- Floating, Comparison
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Stress Disorders, Post-Traumatic
Telephone Case Monitoring (TCM) for Veterans With Post-Traumatic Stress Disorder (PTSD)
The purpose of this study is to test whether providing PTSD patients additional support by telephone (in addition to usual outpatient care) after they discharge from residential treatment improves those patients' outcomes and…
- Trial name
- TCM-PTSD (NCT00288860)
- Testing
- Telephone monitoring, Treatment-As-Usual
- Where
- 5 sites in United States
- Volunteers
- 837 people
- Sponsor
- VA Office of Research and Development
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