Clinical trials: Stress Disorder, Post-Traumatic
Post-Traumatic Stress Disorder
Effectiveness of Trauma-Focused Cognitive Behavioral Therapy in Treating Children With Post-Traumatic Stress Disorder
This study will compare the effectiveness of trauma-focused cognitive behavioral therapy versus standard care in treating children with post-traumatic stress disorder.
- Trial name
- NCT00614068
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT), Treatment as usual (TAU)
- Where
- 8 sites in United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
PTSD
Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSD
PTSD is a chronic mental health condition that drastically reduces an individual's quality of life Dextrose injection with a small needle has been used for chronic pain patients and observational results have shown it to be…
- Trial name
- NCT07382596
- Testing
- Dextrose 5% in water bilateral injection, Normal saline bilateral injection
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Dr. Dean Reeves Clinic
Posttraumatic Stress Disorder
Decision Aid in Veterans With Posttraumatic Stress Disorder
The purpose of this study is to examine the effects of a decision aid on veterans with posttraumatic stress disorder (PTSD) presenting for care.
- Trial name
- NCT00908440
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- White River Junction Veterans Affairs Medical Center
PTSD, Post Traumatic Stress Disorder
Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery
The overall strategy is to recruit veterans with PTSD who report minimal current cannabis use but are interested in or considering therapeutic cannabis to manage mental health symptoms (anxiety, depression, PTSD and/or…
- Conditions
- PTSD, Post Traumatic Stress Disorder, Suicide, Cannabis Use
- Trial name
- CAPER (NCT06222268)
- Testing
- Cannabidiol (CBD) only, Delta-9-tetrahydrocannabinol (THC) only, THC:CBD 1:1
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Leslie Lundahl
Post Traumatic Stress Disorder
SEE FAR CBT Intervention for Adults With PTSD
This single-arm clinical intervention study evaluates a 12-session SEE FAR CBT intervention for adults aged 18 years and older with posttraumatic stress disorder (PTSD).
- Trial name
- NCT07720674
- Testing
- SEE FAR CBT
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Community Stress Prevention Center
Post-Traumatic Stress Disorders
Mechanistic Pathways of Mindfulness Meditation in Post-traumatic Stress Disorder.
The purpose of this study is to find out how meditation influences certain systems in the body: nervous system, hormonal system, and respiratory system.
- Trial name
- NCT00778960
- Testing
- Slow Breathing, Meditation, Meditation and slow breathing
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Oregon Health and Science University
PTSD, Firearm Injury
Project Safe Guard-Trauma
The goal of this randomized controlled trial is to determine if a counseling intervention, Project Safe Guard-Trauma (PSG-T), increases secure firearm storage practices in adults who screen positive for posttraumatic stress…
- Conditions
- PTSD, Firearm Injury, Suicide Prevention, Firearm Safety
- Trial name
- PSG-T (NCT06876740)
- Testing
- Project Safe Guard - Trauma, Project Safe Guard
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- University of Colorado, Denver
Violence, Depression
A Pilot Evaluation of the Pregnant Moms' Empowerment Program
This project will use a longitudinal design with assessments at baseline (T1), post-treatment (T2), 3 month post-partum (T3), 1 year postpartum (T4) and 3.5-5 years postpartum to examine whether the PMEP improves participants'…
- Conditions
- Violence, Depression, Posttraumatic Stress Disorder, Parenting
- Trial name
- NCT05011825
- Testing
- Pregnant Moms' Empowerment Program
- Where
- 2 sites in United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
PTSD, Anxiety, Post Traumatic
Xyrem for Treatment Refractory Insomnia Due to PTSD
Xyrem (sodium oxybate) is an agent with the propensity to improve slow wave sleep and sleep efficiency. It is FDA approved to treat cataplexy (drop attacks) associated with narcolepsy (sleep attacks).
- Trial name
- NCT00330291
- Testing
- Xyrem
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Post-Traumatic Stress Disorder, Adjustment Disorders
MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers and First Responders
The purpose of this study is to assess the safety and efficacy of MDMA-Assisted Therapy on Frontline Health Care Workers and First Responders suffering from symptoms of Post-Traumatic Stress.
- Trial name
- NCT05455996
- Testing
- MDMA
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Nautilus Sanctuary
Posttraumatic Stress Disorder (PTSD)
Two Stepped Care Models for Posttraumatic Stress Disorder (PTSD) Among Cambodian Refugees With PTSD
This project aims to investigate the efficacy of two models to treat Posttraumatic Stress Disorder (PTSD) for Cambodian refugees in primary care.
- Trial name
- NCT01542372
- Testing
- Medication augmentation, CBT
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Massachusetts General Hospital
Stress Disorders, Post-Traumatic
A Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder (PTSD)
To evaluate the safety, efficacy and tolerability of brexpiprazole (with placebo) as monotherapy or combination therapy with Zoloft (sertraline) in adults with PTSD.
- Trial name
- NCT03033069
- Testing
- Brexpiprazole, Sertraline
- Where
- 54 sites in United States
- Volunteers
- 336 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Adolescent Behavior, Psychosocial Functioning
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
This study will deploy a scalable secondary prevention program that leverages existing foster youth transition services to improve mental health functioning and service use before and after exiting foster care.
- Conditions
- Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior
- Trial name
- NCT06019377
- Testing
- Stronger Youth Networks and Coping (SYNC)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Portland State University
Trauma, Nervous System
Northwest Therapies Trauma Psilocybin Study Compassionate Use Study
The on-boarding of unregulatable trauma in the United States has reached 20%, which is 1/5 of the population. A population of this magnitude, by definition has now reached an epidemic classification.
- Trial name
- NWTTPS (NCT05042466)
- Testing
- Trauma
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NWTraumatherapies
PTSD, Substance Use Disorders
Cognitive Behavioral Therapy (CBT) for PTSD in Veterans With Co-Occurring SUDs
With this research, the investigators hope to learn if cognitive behavioral therapy (CBT) for posttraumatic stress disorder (PTSD) works in people who have both PTSD and problems with drugs or alcohol.
- Trial name
- CBT (NCT01357577)
- Testing
- Cognitive behavioral therapy for PTSD
- Where
- 3 sites in United States
- Volunteers
- 129 people
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder, Posttraumatic Stress Disorder
Biopsychosocial Effect of Service Dog Training on Post-traumatic Stress (PTS) and Post Concussive Symptoms
Preliminary clinical evidence suggests that Service Members with symptoms of post-traumatic stress disorder (PTSD) or Post Traumatic Stress (PTS) who participate in the Service Dog Training Program (SDTP) report improved physical…
- Conditions
- Post-traumatic Stress Disorder, Posttraumatic Stress Disorder, Traumatic Brain Injury
- Trial name
- NCT03907254
- Testing
- Service Dog Training Program
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Posttraumatic Stress Disorder
Client-directed Cognitive Processing Therapy
This study will take place over approximately 6 months and includes 3 assessment appointments (where information will be gathered, but no direct treatment provided) and 12 treatment sessions of cognitive processing therapy if…
- Trial name
- CPT (NCT02684994)
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Indianapolis
Combat Disorders, Stress Disorders, Post-Traumatic
Motivational Interviewing to Engage Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans in Mental Health Treatment
The goal of this randomized controlled trial is to evaluate the efficacy of telephone-administered motivational interviewing (TAMI) to enhance VA mental health treatment engagement among veterans of Operations Enduring Freedom…
- Conditions
- Combat Disorders, Stress Disorders, Post-Traumatic, Depression, Substance-Related Disorders
- Trial name
- NCT00419029
- Testing
- telephone-administered motivational interviewing, control
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
Anxiety and Fear, PTSD
K08 VR Fear Conditioning
The goal of this clinical trial is to learn how people respond to fear-related experiences in a virtual reality (VR) environment.
- Conditions
- Anxiety and Fear, PTSD, Veteran
- Trial name
- NCT07216222
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Postpartum Complication, Postpartum
Postpartum Care in the NICU Multi-Site Breastfeeding
Parents of infants in the neonatal intensive care unit (NICU) face unique barriers to long-term breastfeeding and lactation. The physical and emotional demands of having a critically ill or premature newborn combined with the…
- Conditions
- Postpartum Complication, Postpartum, PTSD, PTSD (Childbirth-Related)
- Trial name
- PeliCaN (NCT07881731)
- Testing
- NICU-informed postpartum doula support
- Where
- 11 sites in United States
- Volunteers
- 640 people
- Sponsor
- Children's Hospital of Philadelphia
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