Clinical trials: Stress Disorder, Post-Traumatic
PTSD - Post Traumatic Stress Disorder
The Effect of Using the Combat Attention App on the Risk of Post-traumatic Symptoms
Military service and reserve duty in combat units entails exposure to traumatic events that require mental adjustment. In light of the results of controlled studies that proved the effectiveness an response-time based mechanized…
- Trial name
- NCT06710145
- Testing
- Combat Attention Training
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Tel Aviv University
Sleep Initiation and Maintenance Disorders, Stress Disorders, Posttraumatic
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
Post-traumatic stress disorder (PTSD) is a common consequence of combat that can result in trauma-related hyperarousal and sleep disturbances.
- Trial name
- NCT03642028
- Testing
- Suvorexant
- Where
- 4 sites in United States
- Volunteers
- 190 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injuries, TBI (Traumatic Brain Injury)
Rehabilitation Through Virtual Immersion & Integrated Exposure for Mild Traumatic Brain Injury (ReVIVE for mTBI)
The primary goal of this study is to evaluate the effectiveness of an integrated therapeutic model - combining VR and standard psychotherapy in improving executive function and hyperarousal adults impacted with mTBI.
- Conditions
- Traumatic Brain Injuries, TBI (Traumatic Brain Injury), MTBI - Mild Traumatic Brain Injury, mTBI
- Trial name
- ReVIVE (NCT07890337)
- Testing
- Virtual Reality, Standard Psychotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Stress Disorders, Post-traumatic
Treatment of Posttraumatic Stress Disorder in Kosovar High School Students Using Mind-Body Skills Groups
The purpose of this study is to determine whether the participation in a group program which includes meditation, biofeedback, drawings, autogenic training, genograms, and a variety of movement and breathing techniques will…
- Trial name
- NCT00136357
- Testing
- Mind-Body Skills Groups
- Where
- Federal Republic of Yugoslavia
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- The Center for Mind-Body Medicine
Stress Disorders, Post-Traumatic
Using the Multiphase Optimization Strategy to Adapt Cognitive Processing Therapy
Cognitive Processing Therapy (CPT) consists of discrete therapeutic components that are delivered across 12 sessions, but most Veterans never reach session 12, and those who drop out receive only 4 sessions on average.
- Trial name
- CPT MOST (NCT05220137)
- Testing
- Modified A-B-C: Working with Events, Thoughts, and Feelings, Challenging Questions, Patterns of Problematic Thinking
- Where
- 3 sites in United States
- Volunteers
- 271 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Cognitive Training for Functioning in PTSD
The proposed study will test a novel, computerized treatment for posttraumatic stress disorder (PTSD) to determine if it helps Veterans functionally recover as measured by reduced cognitive disability and PTSD symptoms.
- Trial name
- NCT07693686
- Testing
- COGENT (Cognitive ENhancement Training)
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- VA Office of Research and Development
Mental Health, Depression
Designing a Mobile App to Support Academic Success for Student Veterans
Compared to civilian students in higher education, student Veterans have high rates of mental health disorders (e.g., Depression: 24% vs 12.1%).
- Conditions
- Mental Health, Depression, Post-Traumatic Stress Disorder, Anxiety
- Trial name
- NCT05344092
- Testing
- VetEd Mobile Application
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Stress Disorders, Post-Traumatic
Enhancing Prolonged Exposure With Cannabidiol to Treat Posttraumatic Stress Disorder
The primary goal of this pilot project is to demonstrate the safety and feasibility of using Cannabidiol (CBD) in combination with standard of care prolonged exposure (PE) psychotherapy to reduce PTSD symptoms.
- Trial name
- NCT05132699
- Testing
- Cannabidiol (CBD) oral solution, Massed Prolonged Exposure (mPE)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Development of PTSD After Natural Disaster
Development of Post Traumatic Stress Disorder After Natural Disaster
A survey (patient self-report) of patients presenting to UAB emergency room, outpatient trauma clinics and substance abuse center for symptoms of post-traumatic stress disorder and maladaptive coping responses after the…
- Trial name
- NCT01661452
- Testing
- Referral to counseling services if desired
- Where
- United States
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Psychological Distress, Depression
Peer Intervention to Improve Access Among Rural Women Veterans With Psychological Distress and Unmet Social Needs
This research project will refine and evaluate delivery of a peer-delivered evidence-based intervention to improve perceived access and actual engagement with mental health treatment and social resource service use among rural…
- Conditions
- Psychological Distress, Depression, PTSD, Anxiety
- Trial name
- EMBER (NCT05477706)
- Testing
- Personalized Support for Progress (PSP), Tailored Referral (TR)
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Syracuse VA Medical Center
Posttraumatic Stress Disorder, Traumatic Brain Injury
Cognitive REmediation After Trauma Exposure Trial = CREATE Trial
This study will evaluate the efficacy of methylphenidate and galantamine in the treatment of persistent cognitive symptoms associated with posttraumatic stress disorder (PTSD) and/or traumatic brain injury (TBI).
- Trial name
- CREATE (NCT01416948)
- Testing
- Methylphenidate Hydrochloride 20 mg, Galantamine 12 mg
- Where
- 7 sites in United States
- Volunteers
- 32 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Post Traumatic Stress Disorder, PTSD
Community-Based Telemedicine to Reduce Risk to Georgia Veterans With Post Traumatic Stress Disorder
The investigator proposes to examine treatment for Posttraumatic Stress Disorder for Veterans who served in Iraq and Afghanistan provided through telemedicine which connects patients to doctors in different locations using the…
- Trial name
- NCT01623219
- Testing
- Prolonged Exposure Therapy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Trauma and Stressor Related Disorders, Post Traumatic Stress Disorder
Comparing Standard vs. Modified Reconsolidation Blockade for the Treatment of Psychological Trauma
The investigators propose to examine a mismatch-based method of reconsolidation blockade for the treatment of psychological trauma in military personnel and Federal police officers.
- Conditions
- Trauma and Stressor Related Disorders, Post Traumatic Stress Disorder, Acute Stress Disorder, Adjustment Disorders
- Trial name
- NCT04982211
- Testing
- Propranolol
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Douglas Mental Health University Institute
Posttraumatic Stress Disorder
Hypnotherapeutic Olfactory Conditioning for Posttraumatic Stress Disorder (PTSD)
Chronic combat-related posttraumatic stress disorder can be difficult to treat. The investigators believe that hypnosis, with a stress on the sensation of scent which often plays a role in the traumatic memories, can offer help…
- Trial name
- NCT00784771
- Testing
- Hypnotherapeutic Olfactory Conditioning (HOC)
- Where
- Israel
- Volunteers
- 36 people
- Sponsor
- Herzog Hospital
Chronic Pain, Headache, Migraine
Feasibility of Using Holographic Memory Resolution® (HMR) in Patients/Clients With Pain
Study Purpose: This study will explore the feasibility of administering Holographic Memory Resolution® (HMR) to adults who are experiencing chronic pain for 6 months or more.
- Conditions
- Chronic Pain, Headache, Migraine, Stress Disorders, Post-Traumatic
- Trial name
- NCT05001399
- Testing
- Holographic Memory Resolution® (HMR)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Billings Clinic
Post Traumatic Stress Disorder, MDMA ('Ecstasy')
Preliminary Effectiveness of Hybrid Individual and Group MDMA-assisted Therapy for War-related PTSD
The overall objective of this study is to use standard clinical measures to explore the safety and preliminary effectiveness of open-label MDMA-assisted therapy with a flexible dose of methylenedioxymethamphetaminel, in…
- Trial name
- NCT05732155
- Testing
- methylenedioxymethamphetamine
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Guy Schusheim
Post-Traumatic Stress Disorder
Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD)
This was a six-week pilot study testing the efficacy of tramadol extended-release (ER) for posttraumatic stress disorder (PTSD).
- Trial name
- NCT01517711
- Testing
- Tramadol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Alcohol Use Disorder, Posttraumatic Stress Disorder
Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship
Intimate partner violence (IPV) is a serious public health problem that results in significant health and economic burdens including mortality, morbidity, and poor treatment outcomes.
- Conditions
- Alcohol Use Disorder, Posttraumatic Stress Disorder, Couples
- Trial name
- NCT05786157
- Testing
- Alcohol Administration
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Medical University of South Carolina
Posttraumatic Stress Disorder
Prevention of Posttraumatic Stress Disorder (PTSD) With Early Hydrocortisone Treatment: Pilot
People experience a wide range of outcomes following a traumatic event. Although rates differ depending on type of trauma, 20-60% of trauma victims may develop posttraumatic stress disorder (PTSD).
- Trial name
- NCT00597857
- Testing
- Hydrocortisone
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Kent State University
Domestic Violence, Post-Traumatic Stress Disorder
Mental Health Symptoms and Intimate Partner Violence
Using a touch screen computer, the researchers are screening emergency department patients for intimate partner violence and mental health issues.
- Conditions
- Domestic Violence, Post-Traumatic Stress Disorder, Depression
- Trial name
- NCT00166075
- Testing
- Computer screen with community resource printout
- Where
- United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Emory University
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