Clinical trials: Stress Disorder, Post-Traumatic
Nightmares, Insomnia
Treating Insomnia & Nightmares After Trauma: Impact on Symptoms & Quality of Life
Exposure to trauma, especially when it manifests as Posttraumatic Stress Disorder (PTSD), results in numerous negative consequences for patients, families, and society.
- Conditions
- Nightmares, Insomnia, Posttraumatic Stress Disorder
- Trial name
- NCT01009112
- Testing
- PTSD + IRT/CBT-I, PTSD + Supportive Care Therapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, San Diego
Post-Traumatic Stress Disorder
Combined Ketamine and eCBT Intervention for PTSD
An open label RCT assessing the efficacy of a combined treatment approach for PTSD, using Ketamine infusions and online Cognitive Behavioural Therapy.
- Trial name
- NCT04771767
- Testing
- Ketamine, Online Trauma-Focused Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Queen's University
Post Traumatic Stress Disorder, Complex Posttraumatic Stress Disorder
Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress
In the last four years alone, residents of Puerto Rico have experienced a slew of natural disasters including Hurricane Maria in 2017, earthquakes in 2019 and 2020, the continued COVID-19 pandemic from 2020-2022, and most…
- Conditions
- Post Traumatic Stress Disorder, Complex Posttraumatic Stress Disorder, Stress, Burn Out
- Trial name
- NCT05701111
- Testing
- Start with the Heart Students, Start with the Heart Teachers, Cue Centered Therapy Counselors
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 80,800 people, healthy volunteers welcome
- Sponsor
- Stanford University
Depression, Anxiety Disorders
Focused Ultrasound Amygdala Neuromodulation
The purpose of the study is to examine the feasibility and potential efficacy of low-intensity focused ultrasound as a method of modulating amygdala function to promote improvements in symptoms of an affective disorder.
- Conditions
- Depression, Anxiety Disorders, Bipolar Depression, Ptsd
- Trial name
- NCT05228964
- Testing
- Focused ultrasound
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Lung Cancer, Prostate Cancer
Enbrel Versus Placebo With Radiation Therapy to Combat Fatigue and Cachexia
Patients who receive radiation therapy often have fatigue or a decrease in feeling well causing a "wasting" away. For patients with advanced disease of lung cancer, prostate cancer, or cancer that has spread to the bone, it is…
- Conditions
- Lung Cancer, Prostate Cancer, Neoplasm Metastasis, Bone Cancer
- Trial name
- NCT00127387
- Testing
- Enbrel
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Stress Disorders, Post-Traumatic, HIV Infections
Stress-Reducing Interventions in HIV+ Patients: Pilot
The primary aim of this project is to examine the efficacy of prolonged exposure (PE) therapy at reducing HIV-related PTSD symptoms, increasing adherence to antiretroviral medication regimens, and increasing health-related…
- Trial name
- PEACH (NCT00599599)
- Testing
- Prolonged Exposure Therapy
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Kent State University
PTSD, Suicidal Thoughts and Behaviors
Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study
This study will be the first to use brain imaging to explore how cannabis affects the brain and inflammation in U.S. military veterans with PTSD.
- Conditions
- PTSD, Suicidal Thoughts and Behaviors, PTSD Symptoms, Depressive Symptoms
- Trial name
- CNS (NCT07222306)
- Testing
- 1-(2-[+F]fluoroethyl)-L-tryptophan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wayne State University
Stress Disorders, Post-Traumatic
Ketamine Infusion Therapy for PTSD in Combat Veterans
Klarisana is conducting an observational study in San Antonio, Texas to see if there are tangible improvements in the symptoms of post traumatic stress disorder (PTSD) in combat veterans after receiving a series of six low-dose…
- Trial name
- NCT03088384
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Klarisana Physician Services PLLC
Posttraumatic Stress Disorder, Shame
NET for SGBV Survivors in Eastern DR Congo
Throughout the last 10 years Narrative Exposure Therapy (NET) has evolved as one of the most effective, culturally sensitive trauma interventions.
- Trial name
- NCT02989987
- Testing
- Narrative Exposure Therapy, Social Support
- Where
- Germany
- Volunteers
- 201 people
- Sponsor
- University of Konstanz
Alcohol Dependence, Stress Disorders, Post-Traumatic
Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).
Prazosin is an alpha-1 adrenergic receptor antagonist that has been used successfully in the treatment of trauma nightmares and sleep disturbance in combat veterans with PTSD, and alcohol dependence.
- Trial name
- NCT00744055
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Yale University
PTSD
Web and Shared Decision Making for Reserve/National Guard Women's PTSD Care
Women and Reserve/National (RNG) Veterans are among the fastest growing groups of new VA users. While PTSD is prevalent in this group, most women don't access or complete needed treatment.
- Trial name
- NCT01710306
- Testing
- Nurse Care Manager (NCM)
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD
Online and Mobile Mindfulness Intervention to Reduce Distress
The purpose of this study is to test whether a mobile app can improve mindful awareness, attention, and psychological well-being in Veterans and cancer survivors with mild to moderate PTSD symptoms.
- Trial name
- NCT04035304
- Testing
- Mindfulness Coach
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- VA Palo Alto Health Care System
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Hearing Impairment, Hearing Aid Fitting
Blast Exposed Veterans With Auditory Complaints
The purpose of this study is to study blast-exposed Veterans who report hearing handicap but show normal or near normal results on standard audiometric testing.
- Trial name
- NCT02122458
- Testing
- mild-gain hearing aids with high-frequency emphasis over 6-months
- Where
- 3 sites in United States
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD, Depression
Increasing Psychological Resilience in Combat Soldiers Applying Advanced Eye-Tracking-Based Attention Bias Modification
Military service in combat units entails exposure to traumatic events that require mental adjustment. To develop and efficiently apply attention bias modification interventions aimed at enhancing soldiers' mental resilience, it…
- Conditions
- PTSD, Depression, Anxiety Disorders
- Trial name
- NCT05294848
- Testing
- Gaze-Contingent Feedback Training, Attention Bias Modification, Neutral Control
- Where
- Israel
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Mental Stress, Emotional Stress
Trauma Informed Care for Newly Resettled Refugees
The main purpose of this study is to evaluate early-phase interventions for refugee wellness promotion and build evidence for dissemination of the intervention model and curricula through refugee resettlement programs, local and…
- Trial name
- NCT03288935
- Testing
- TICM, TICO
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Post-traumatic Stress Disorder (PTSD)
Post-natal Post-traumatic Stress: Impact of an Early Dyadic Intervention Though Interaction Guidance Therapy on Maternal Sensitivity and Reduction of Maternal Stress
The aim of this study is to assess if an early therapeutic management focused on the mother-baby interaction using Interaction Guidance Therapy (IGT) with video feedback, brings an improvement of the maternal sensitivity in the…
- Trial name
- EVAGIT (NCT04916938)
- Testing
- Interaction Guidance Therapy, Mother's child psychotherapeutic session, Interview
- Where
- 10 sites in France
- Volunteers
- 36 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Posttraumatic Stress Disorder, PTSD
Efficacy of 60-minute Versus 90-minute Sessions in Treating PTSD Using Prolonged Exposure
The purpose of this study is to determine whether 60-minute sessions of prolonged exposure (PE) are as effective as the standard 90-minute session for treating posttraumatic stress disorder (PTSD).
- Trial name
- NCT01911585
- Testing
- Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Pennsylvania
Anxiety Disorders, Stress Disorders, Post-Traumatic
MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients
Pregnant and postpartum patients hospitalized for medical complications experience high rates of depression, anxiety, and trauma-related symptoms, yet access to timely psychiatric care during obstetric hospitalization is limited.
- Conditions
- Anxiety Disorders, Stress Disorders, Post-Traumatic, Pregnancy, High Risk, Depressive Disorder, Major
- Trial name
- MOCHA (NCT07540585)
- Testing
- Collaborative Mental Health Care Program (CMHCP)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Indiana University
Post Traumatic Stress Disorder
Participation in Occupations and Perception of Quality of Life, Comparing Adults With and Without PTSD
This study assesses the relationship between participation and quality of life the way adults with and without Post Traumatic Stress Disorder (PTSD) experience it in everyday life.
- Trial name
- PTSD (NCT03350438)
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Ziv Hospital
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