Clinical trials: Stress Disorder, Post-Traumatic
Post-Traumatic Stress Disorder, Combat Disorders
Trauma Management Therapy for OEF and OIF Combat Veterans
This trial will evaluate the efficacy and efficiency of Trauma Management Therapy (TMT; Frueh, Turner, Beidel, 1996; Beidel, Frueh, Uhde, under preparation), which combines individual virtual reality (VR) assisted exposure…
- Trial name
- TMT (NCT02809326)
- Testing
- 17 week Exposure Therapy Control Arm, Trauma Management Therapy, Intensive 3-Week Trauma Management Therapy
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Stress Disorders, Post-Traumatic, Smoking
CPT and Smoking Cessation
Posttraumatic stress disorder (PTSD) and cigarette smoking are both associated with significant impairment in Veterans and cost to the Veterans' Affairs (VA) system.
- Trial name
- NCT01901848
- Testing
- Cognitive Processing Therapy (CPT), Bupropion, nicotine replacement therapy (NRT)
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post-Traumatic
CPT-fMRI Study for PTSD
Posttraumatic stress disorder (PTSD) is prevalent mental illness (~9% life-time) that results from exposure to trauma. As it is associated with vastly heterogeneous origins, accurate diagnosis and optimal treatment strategies are…
- Trial name
- NCT03229915
- Testing
- cognitive processing therapy
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Depression, Physical Inactivity
Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety
"Braining" is a clinical method for physical exercise as adjunctive therapy in psychiatric care. The core components are personnel-led group training sessions and motivating contact with psychiatric staff, as well as measurement…
- Conditions
- Depression, Physical Inactivity, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT05157386
- Testing
- Braining
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Stockholm
Stress Disorders, Post-Traumatic, Stress Related Disorder
Mindfulness-SOS for Refugees
Worldwide, refugees and asylum seekers suffer at high rates from trauma and stress-related mental health problems. The research group therefore developed, and initially piloted in a single-site open trial, a novel mindfulness…
- Trial name
- NCT05616286
- Testing
- Mindfulness-SOS for Refugees
- Where
- Israel
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Post Traumatic Stress Disorder
An Evaluation of the Safety and Efficacy of Methylone for the Treatment of PTSD
This study is evaluating the safety and efficacy of methylone in adults with PTSD. The study is conducted in two parts. Part A is open-label and will enroll up to 15 participants with PTSD Part B is randomized (1:1:1)…
- Trial name
- IMPACT-2 (NCT06215261)
- Testing
- Methylone
- Where
- 12 sites in United States, Australia and 1 more
- Volunteers
- 62 people
- Sponsor
- Transcend Therapeutics
PTSD
Mindful Yoga Therapy as an Adjunctive Treatment for PTSD Among OEF/OIF Veterans
The primary objective of the current study is to establish the safety and acceptability of Mindful Yoga Therapy as an adjunctive treatment for posttraumatic stress disorder (PTSD) among Operation Enduring Freedom/Operation Iraqi…
- Trial name
- NCT01521442
- Testing
- Mindful Yoga Therapy, Wait-list Control
- Where
- United States
- Sponsor
- VA Connecticut Healthcare System
Posttraumatic Stress Disorder
Imaginal Exposure & D-Cycloserine (DCS) for Posttraumatic Stress Disorder (PTSD)
This study proposes to evaluate the effects of D-cycloserine (DCS) combined with cognitive-behavioral treatment with exposure therapy in a sample of patients who developed posttraumatic stress disorder (PTSD) as a consequence of…
- Trial name
- NCT00875342
- Testing
- DCS
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Weill Medical College of Cornell University
Post-Traumatic Headache
Prazosin for Post-Concussive Headaches
Mild traumatic brain injury (mTBI) caused by blast effects of explosive devices has been called the "signature injury" of soldiers who served in the Iraq and Afghanistan conflicts.
- Trial name
- NCT02965027
- Testing
- Prazosin
- Where
- 2 sites in United States
- Volunteers
- 89 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Stress, Anxiety
Stress Resilience Training System
The Stress Resilience Training System (SRTS) program is a stress reduction and resilience building system that blends cognitive training to anticipate the effects of stress with advanced biofeedback to mitigate stress effects and…
- Conditions
- Stress, Anxiety, Depression, PTSD
- Trial name
- SRTS (NCT01599624)
- Testing
- Stress Resilience Training System (SRTS), Progressive Muscle Relaxation (PMR)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Cognitive Behavioral Therapy
Cognitive Behavioral Therapy for Post-Traumatic Stress Disorder
The current study is designed to measure the role of cognitive behavior therapy with PTSD patients. There are following objectives of this current study, such as 1.
- Trial name
- NCT06177223
- Testing
- Cognitive Behavioral therapy
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Government College University Faisalabad
Sexual Assault and Rape, Suicidal Thoughts
BEAR for Women Who Have Experienced Sexual Assault and Have Suicidal Thoughts
The goal of this clinical study is to learn if the BEAR intervention effects outcome in women who have experienced sexual assault (broadly defined) and who have suicidal thinking.
- Trial name
- BEAR-SI (NCT07902050)
- Testing
- BEAR Therapeutic Group
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Stanford University
PTSD
Is Olfaction the Key to PTSD
Participants arriving to the ED following a potentially traumatic event such as a motor vehicle accident will be recruited into the study.
- Trial name
- NCT05640882
- Testing
- VRET, VRET OLFACTION
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Posttraumatic Stress Disorder (PTSD)
Increasing Engagement in PTSD Treatment Through Patient Education and Patient Choice
The purpose of this program is to compare two different methods of matching a Veteran to a PTSD treatment.
- Trial name
- NCT01446146
- Testing
- Informed decision making
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Michael E. DeBakey VA Medical Center
PTSD, Insomnia, Secondary
Written Exposure Therapy and App-Delivered Mindfulness Meditation for PTSD in China: A Pilot Study
The goal of this study is to use a pilot RCT to assess the effectiveness of Written Exposure Therapy (WET) and a mindfulness-based app (MBA) for managing PTSD and comorbid insomnia in China.
- Trial name
- NCT06394700
- Testing
- written exposure therapy, Written Exposure Therapy plus Mindfulness-Based App (WET + MBA), Minimal Contact Control (MCC)
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Peking University
PTSD - Post Traumatic Stress Disorder
Virtual Reality Assisted Trauma Focused CBT
Virtual Reality (VR) is becoming an increasingly important tool in mental healthcare, offering new ways to enhance patient treatment.
- Trial name
- NCT07914634
- Testing
- VR Photoscan, Trauma-Focused Cognitive Behavioural Therapy (TF-CBT)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Queen's University, Belfast
Post Traumatic Stress Disorder, Traumatic Brain Injury
Cannabidiol as a Treatment for PTSD and PTSD Comorbid With TBI
This will be a randomized placebo controlled study to test the efficacy of cannabidiol (CBD) as a treatment for symptoms of post-traumatic stress disorder (PTSD).
- Trial name
- NCT04550377
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- NYU Langone Health
Traumatic Brain Injury, Post Traumatic Stress Disorder
Executive Dysfunction and Self-Harm Behavior: An Examination of Veterans With TBI, PTSD, or Both
1. To determine whether tasks taken from the field of cognitive neuroscience can detect and distinguish impairments in executive function above and beyond standard neuropsychological measures in individuals with: a.) Mild…
- Conditions
- Traumatic Brain Injury, Post Traumatic Stress Disorder, Suicide, Self-Injurious Behavior
- Trial name
- NCT01334463
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
PostTraumatic Stress Disorder
Closed Loop Vagal Nerve Stimulation for Patients With Posttraumatic Stress Disorder
The tasks of the project are to map the potency and kinetics of the neurologic, autonomic peripheral, inflammatory, and behavioral responses to vagal nerve stimulation (VNS) vs.
- Trial name
- NCT02992899
- Testing
- GammaCore/electroCore non-invasive VNS device, O-15 water
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Emory University
Post Traumatic Stress Disorder, Substance Use Disorders
Virtual Mantram Program for Patients With PTSD and SUD
The purpose of this study is to evaluate a virtual Mantram repetition program for adults with PTSD and substance use disorders. The program involves repetition of a personalized Mantram, which is a word or short phrase with…
- Trial name
- NCT05058963
- Testing
- Mantram repetition program
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- Centre for Addiction and Mental Health
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