Clinical trials: Stress Disorder
Cardiovascular Diseases, Aging
Cardio-vascular Protective Effects of Wolfberry in Middle-aged and Older Adults
This purpose of this study is to assess the impact of consuming wolfberry on cardiovascular risk in Singapore's middle-aged and older adults.
- Trial name
- NCT03535844
- Testing
- Wolfberry, Healthy diet
- Where
- 2 sites in Singapore
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Insomnia, Posttraumatic Stress Disorder
Suvorexant and Trauma Related Insomnia
Problems sleeping are common after exposure to highly threatening experiences and can occur with and without a diagnosis of posttraumatic stress disorder (PTSD).
- Trial name
- NCT02704754
- Testing
- suvorexant
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Howard University
Generalized Anxiety Disorder
Stress Reduction Techniques and Anxiety: Therapeutic and Neuroendocrine Effects
Current therapies for Generalized Anxiety Disorder (GAD) have limited effectiveness. This study measures the efficacy of two different approaches to reducing anxiety and stress.
- Trial name
- NCT01033851
- Testing
- Mindfulness Based Stress Reduction, Stress Management Education
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Massachusetts General Hospital
Obesity
Evaluation of Safety and Health Involvement For Truck Drivers
The current project is a randomized, controlled evaluation of a new weight loss and health promotion intervention for truck drivers.
- Trial name
- SHIFT (NCT02105571)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Depression, Anxiety
C-STRESS: A Mental Health App for College Students With Depression
The goal of this pilot study is to examine the feasibility of the prototype C-STRESS app with 3 college students from UCI with clinically significant depression (scored ≥ 10 on the Patient Health Questionnaire-9).
- Conditions
- Depression, Anxiety, Stress, Psychological, Mobile Phone Use
- Trial name
- C-STRESS (NCT05776901)
- Testing
- C-STRESS
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Benten Technologies, Inc.
Depression, Anxiety
Neural Changes Associated With a Mindfulness-based Intervention for Young Adults With Childhood Maltreatment
Childhood trauma is remarkably prevalent, and it has long lasting impact on mental health and neural development. This trial aims to see whether the 8-week mindfulness based intervention can reduce stress related psychological…
- Conditions
- Depression, Anxiety, PTSD, Trauma, Psychological
- Trial name
- NCT02447744
- Testing
- Mindfulness based intervention
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stress Disorders, Post-Traumatic, Depression
Development of a Patient Centered Mental Health Intervention for Recent Veterans
Recent Veterans of the OIF/OEF/OND conflicts are presenting in VA care with high rates of: PTSD, depression, anxiety, and alcohol abuse, reporting significant difficulties with community reintegration, and dropping out of mental…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Anxiety, Substance-Related Disorders
- Trial name
- PCC MH (NCT02943408)
- Testing
- person-centered mental health intervention, health and wellness
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Group Based Exposure Therapy for Combat-Related PTSD
The purpose of this randomized controlled trial is to determine if Group Based Exposure Therapy (GBET) is more effective than treatment as usual in reducing the symptoms of war-related Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT00535223
- Testing
- Group Based Exposure Therapy, Present Centered Group Therapy
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- US Department of Veterans Affairs
Premature Birth, Maternal Distress - Delivered
Heart Rate Variability and Prematurity
Mothers who deliver prematurely (<37 weeks of gestational age) experience intense stress and anxiety given that their child's survival and development might be compromised.
- Conditions
- Premature Birth, Maternal Distress - Delivered, Stress, Anxiety
- Trial name
- NCT03565874
- Testing
- Heart rate variability biofeedback
- Where
- Switzerland
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Stress Urinary Incontinence
Pippa Pessary Study (Clinical Trial)
This is an open label, interventional, single arm, multi-clinic study where each adult female participant with stress urinary incontinence (SUI) serves as her own control (vaginal pessary use vs. no vaginal pessary).
- Trial name
- NCT05611970
- Testing
- Vaginal pessary
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Liv Labs Inc.
PTSD
Open Label Extension Safety and Efficacy Study of TNX-102 SL Tablets in Military Related PTSD and Related Conditions
This is a 12-week, multicenter, open-label extension study to evaluate the safety and efficacy of TNX-102 SL tablet taken daily at bedtime in patients with Military-Related PTSD or related condition.
- Trial name
- P202 (NCT02421679)
- Testing
- TNX-102 SL
- Where
- 22 sites in United States
- Volunteers
- 159 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Heat Stroke
Efficacy and Safety of Ryanodex® (EGL-4104) as Adjuvant Treatment in Subjects With Exertional Heat Stroke (EHS)
Study EGL-4104-C-1502 is a phase 2, single-site, open-label, randomized, 2-arm parallel study of Ryanodex for the adjuvant treatment of exertional heat stroke (EHS) administered intravenously (IV), to current standard of care…
- Trial name
- NCT02513095
- Testing
- Dantrolene sodium for injectable suspension
- Where
- Saudi Arabia
- Volunteers
- 34 people
- Sponsor
- Eagle Pharmaceuticals, Inc.
Hypertension
A Study of the Effect of Nebivolol to Evaluate Its Vasodilatory Effects in Hypertensive Patients
The study is designed to compare the effects of nebivolol (10, 20, 40mg/day) with another beta blocker, extended-release metoprolol, at a range of doses.
- Trial name
- NCT00648895
- Testing
- Nebivolol, Metoprolol ER (TM)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Forest Laboratories
Post Traumatic Stress Disorder
Expressing Personal Recollections in English or Spanish to Alleviate Traumatic Emotions (Exprésate)
The purpose of this study is to test if expressive writing about traumatic events has positive changes in women living with post-traumatic stress.
- Trial name
- Exprésate (NCT05090839)
- Testing
- Weekly Emotional Disclosure (WED), Weekly Emotional Disclosure (WED) Spanish
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Stress Urinary Incontinence
Altis® 522 Trial - Treatment of Female Stress Urinary Incontinence
The aim of this postmarket study is to compare the safety and effectiveness of the Altis Single Incision Sling (SIS) to an FDA cleared transobturator and/or retropubic sling through 36 months.
- Trial name
- NCT02348112
- Testing
- Altis Single Incision Sling, Transobturator or Retropubic Sling
- Where
- 27 sites in United States, Canada
- Volunteers
- 416 people
- Sponsor
- Coloplast A/S
Domestic Violence
Strength At Home: Veterans' Program (PTSD-Focused Therapy for Anger and Relationship Conflict Among OEF/OIF Veterans)
This is a research study funded by the Department of Defense to test a therapeutic intervention for male combat veterans who engage in intimate partner violence (IPV).
- Trial name
- NCT01435512
- Testing
- PTSD-Focused CBT for Partner Violence
- Where
- 2 sites in United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Boston VA Research Institute, Inc.
Posttraumatic Stress Disorder, Depression
Behavioral Activation for PTSD/Depression Treatment in OIF/OEF Veterans
The present study is a randomized, controlled trial that compares Behavioral Activation (BA) to Treatment As Usual (TAU) in PTSD Specialty clinics, as early psychotherapeutic interventions for OIF/OEF veterans with posttraumatic…
- Trial name
- NCT00805532
- Testing
- Behavioral Activation treatment, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Major Depressive Disorder
rTMS for PTSD Comorbid With Major Depressive Disorder
The purpose of this study is to see how well a treatment called "Repetitive Transcranial Magnetic Stimulation" works for patients who struggle with symptoms of both posttraumatic stress disorder and major depressive disorder.
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Transcranial Magnetic Stimulation, Repetitive
- Trial name
- NCT02273063
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Butler Hospital
Adrenocortical Carcinoma, Peritoneal Carcinomatosis
Surgery and Heated Chemotherapy for Adrenocortical Carcinoma
Background: Adrenocortical carcinoma (ACC) is a rare tumor of the adrenal gland. Few people who develop this disease live more than 5 years after being diagnosed.
- Trial name
- NCT01833832
- Testing
- Cisplatin, Cytoreductive surgery, sodium thiosulfate
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Cancer Institute (NCI)
Depression, Palliative Care
Methylphenidate for Depressed Cancer Patients Receiving Palliative Care
The purpose of this study is to determine whether methylphenidate is an effective treatment for depression and to document the safety and tolerability of methylphenidate in combination with an Selective Serotonin Reuptake…
- Conditions
- Depression, Palliative Care, Cancer, Mental Disorder
- Trial name
- NCT00129467
- Testing
- Methylphenidate, Selective Serotonin Uptake Inhibitor (SSRI)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- US Department of Veterans Affairs
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