Clinical trials: Stress Reaction; Acute
Agitated; State, Acute Reaction to Stress
Dexmedetomidine Combined With Hydromorphone in Tonsillectomy and Adenoidectomy
Tonsillectomy and adenoidectomy is one of the most common pediatric surgeries, and agitation and severe postoperative pain have been considered a very common complications.
- Trial name
- NCT03760809
- Testing
- Dexmedetomidine 0.5μg／kg, Dexmedetomidine 1μg／kg
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Post-traumatic Stress Disorder, Acute Stress Disorder
Feasibility Study of the Self-Care Immediate Stabilization Procedure (ISP) ® After a Traumatic Experience
The study aims to assess the feasibility of an online intervention platform based on the Immediate Stabilization Procedure (ISP®). This intervention targets early trauma reactions, aiming to reduce the risk of future PTSD.
- Trial name
- NCT06277973
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR)
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Normal Subjects
Acute Effects of Artificial Sweeteners or Sugar on Hemodynamic and Metabolic Stress Responses
This exploratory study aims at investigating the acute effects of artificially sweetened and sugar beverage consumption (as compared to water consumption) on acute hemodynamic and metabolic stress response.
- Trial name
- EduStress (NCT02973334)
- Testing
- Ingestion of artificially-sweetened beverages, Ingestion of sugar-sweetened beverages, Ingestion of water
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Acute Stress Response During Orthodontic Mini-screw Placement
Effects of Music Therapy on Stress During Orthodontic Mini-screw Placement
This randomized clinical trial evaluated acute stress responses during orthodontic mini-screw placement and whether listening to music during the procedure influenced these responses.
- Trial name
- NCT07793669
- Testing
- Music Listening Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Himmet YILDIRIM
Stress, Acute Stress Reaction
Impact of Repeated Virtual Reality Training on Markers of Stress
The purpose of this study is to examine whether repeated exposure to an active shooter or target practice virtual reality (VR) scenario alters physiological and psychological stress responses over time.
- Conditions
- Stress, Acute Stress Reaction, Virtual Reality, Active Shooter
- Trial name
- NCT07770880
- Testing
- Active Shooter, Target Practice
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Texas State University
Stress Disorders, Post-Traumatic, Stress Disorders, Traumatic, Acute
Intranasal Neuropeptide Y in Clinical Trial in Level Two Trauma Patients for PTSD and Acute Stress Disorder
Level 2 trauma patients admitted to Westchester Medical Center who consent and meet the inclusion criteria will answer a questionnaire, be tested on Beck Anxiety Index, assessed for vital signs and provide blood and urine samples…
- Trial name
- NCT04071600
- Testing
- Neuropeptide Y
- Where
- 2 sites in United States
- Volunteers
- 117 people
- Sponsor
- New York Medical College
Agitated; State, Acute Reaction to Stress
Preemptive Chlorepheniramine Maleate Reducing Postoperative Agitation
The aim of the study is to identify the role of preoperative chlorepheniramine maleate on alleviating or reducing the severity of postoperative agitation following FESS procedures.
- Trial name
- NCT04293081
- Testing
- Preemptive chlorepheniramine maleate intravenous injection, normal saline
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Stress Response, Mood State
Post-biotic Intervention for Acute Stress Management
The study aims to evaluate the sub-chronic effects of colonic delivery of a post-biotic on stress response, mood state, sleep, and cognition in healthy young subjects with elevated self-reported stress levels.
- Conditions
- Stress Response, Mood State, Sleep, Cognition
- Trial name
- PIAS (NCT06097182)
- Testing
- Post-biotic (Colonic-Delivery capsule), Post-biotic (Regular Administration capsule)
- Where
- Singapore
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Hydration Status, Psychosocial Stress
The Influence of Fluid Intake on Mental Performance
Over half of the adult population in Europe, Asia and Latin America fail to meet adequate water intake guidelines as advised by the European Food Safety Authority (EFSA; 2.5 and 2 litres/day for men and women, respectively coming…
- Conditions
- Hydration Status, Psychosocial Stress, Fluid Intake
- Trial name
- NCT07789847
- Testing
- Modifying daily total fluid intake
- Where
- United Kingdom
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
PTSD
Prevention of Post Traumatic Stress Disorder Following Trauma by Attention Control Training
The purpose of this study is to explore the efficacy of Attention Control Training in preventing the development of Post Traumatic Stress Disorder (PTSD), during the period near after a traumatic event and before PTSD is develop.
- Trial name
- NCT02591485
- Testing
- Attention Control Training
- Where
- Israel
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Yair Bar-Haim
Psychological Stress
Essential Oil Inhalation and Acute Stress Response in Healthy Adults
This randomized, double-blind, placebo-controlled study evaluates the acute physiological and subjective responses to essential oil inhalation in healthy adults.
- Trial name
- DMA (NCT07473544)
- Testing
- Essential Oil Inhalation
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- dōTERRA International
Agitation States as Acute Reaction to Gross Stress
Efficacy of External Nasal Nerve Block in Prevention of Postoperative Agitation Following Nasal Surgeries
Emergence agitation following general anaesthesia may lead to serious complications like self-extubation or removal of catheters, which can lead to hypoxia, aspiration pneumonia, bleeding or reoperation.
- Trial name
- NCT03069027
- Testing
- External nasal nerve block, saline adrenaline, Xylocaine, adrenaline
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al Jedaani Hospital
Acute Stress Reaction, Cognitive Performance
Effect of Transcutaneous Auricular Neurostimulation on Cognitive Performance in a Laboratory Model of Acute Stress Reaction
The objective of this study is to test the effects of transcutaneous auricular neurostimulation (tAN) in treating or preventing performance degradation after an acute stressor.
- Trial name
- ASR (NCT06390267)
- Testing
- Sparrow Hawk (Active)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Spark Biomedical, Inc.
Cardiac Arrest
Removing Surrogates' Uncertainty to Reduce Fear and Anxiety After Cardiac Events
The goal of this study is to test the feasibility and acceptability of an informational website to reduce uncertainty, psychological distress, and caregiver burden among close family members of cardiac arrest patients.
- Trial name
- RESURFACE (NCT06048068)
- Testing
- Educational Informational Platform
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Columbia University
Agitation, Pediatric Disorder
Addition of Magnesium Sulfate to Caudal to Prevent Postoperative Emergence Agitation.
Emergence agitation after sevoflurane anesthesia is still a problem needed to be solved.The aim of the study is to delineate the effect of caudal magnesium sulfate in children undergoing lower abdominal surgery to prevent…
- Trial name
- NCT02164773
- Testing
- Magnesium Sulfate, 0.9%normal saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
PTSD, Substance Use Disorder (SUD)
Adolescent Stress and Substance Intervention Subsequent to Trauma
The long-term goal of this study is to address the adoption of the new trauma center requirement to establish best practices of screening for acute stress with an intervention to prevent both adolescent PTSD and substance use.
- Conditions
- PTSD, Substance Use Disorder (SUD), Acute Stress Disorder
- Trial name
- ASSIST (NCT07197476)
- Testing
- ASSIST Video Intervention
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Anxiety
Integrative Medicine for Hospital Workers Exposed to War
During the "Iron Swords" war in Israel in 2023, the residents of the Gaza Strip and the surrounding area, along with the soldiers of the security service, were exposed to a very high intensity of trauma.
- Trial name
- NCT06190964
- Testing
- Integrative medicine
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Bnai Zion Medical Center
Posttraumatic Stress Disorder, Acute Stress Disorder
Prevention of Intrusive Memories and Posttraumatic Stress Symptoms After Emergency Cesarean Section
This pilot study aims to investigate the effects of a brief computerized intervention (the computer game "Tetris") on intrusive memories and other posttraumatic stress symptoms following an emergency cesarean section.
- Trial name
- NCT02502513
- Testing
- Brief computerized intervention
- Where
- Switzerland
- Volunteers
- 56 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Posttraumatic Stress Disorder, Burns
Early Intervention to Prevent Development of PTSD in Burn Survivors and Their Caregivers
The purpose of this clinical trial is to adapt and test a brief patient-caregiver early intervention designed to reduce posttraumatic stress symptoms in hospitalized burn patients and their caregivers.
- Conditions
- Posttraumatic Stress Disorder, Burns, Traumatic Injury, Acute Stress Disorder
- Trial name
- NCT07656545
- Testing
- Promotion of Emotional Disclosure for Burns (PoED-B), minimally Enhanced Usual Care control (mEUC)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Fear of Spiders, Acute Stress Reaction
The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance Outcomes
This clinical trial aims to evaluate the nature and duration of effects of three FDA-approved medications (propranolol and hydrocortisone) on military-relevant cognitive, emotional, and motor performance following an exposure to…
- Trial name
- NCT06982183
- Testing
- Propranolol, Hydrocortisone
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)