Clinical trials: Stress Reaction; Acute
Anxiety Disorder
SSRI Administration to Reduce Acute Stress Disorder Symptoms and Prevent Depression and PTSD in Physical Trauma Victims
The purpose of this study is to examine the efficacy of escitalopram compared to placebo in reducing Acute Stress Disorder (ASD) symptoms and in preventing the emergence of Post-Traumatic Stress Disorder (PTSD) in patients with…
- Trial name
- NCT00114374
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Ischemic Stroke, Hyperglycemia
Assessment of Markers of Stress in Acute Ischemic Stroke With Hyperglycemia
Hyperglycemia is present in 50 percent of patients with acute ischemic stroke. Patients with hyperglycemia have higher in hospital, 30 and 90 day mortality and morbidity.
- Trial name
- ASIIST (NCT03318679)
- Testing
- No intervention is planned.
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Minnesota
Intensive Care, Child
The Visiting Child and His Family in ICU
According to literature, it's difficult to evaluate the impact of the visit of the child in ICU. Currently, no recommendations are available regarding welcome and accompany children who visit their relative hospitalized in ICU.
- Conditions
- Intensive Care, Child, Acute Stress Disorder, Post Traumatic Stress Disorder
- Trial name
- ENVIFAR (NCT03954522)
- Testing
- interview
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Acute Stress Disorder, Anxiety
GASA-CIR Trail (Guidance and the Symptoms of Acute Stress and Anxiety in Critically Ill Patients Relatives in Intensive Care Unit)
A randomized clinical trial 1:1 among relatives of patients admitted to an intensive care unit, the intervention group will be composed by family members who receive a printed brochure and will be encouraged to visit a website…
- Conditions
- Acute Stress Disorder, Anxiety, Depression
- Trial name
- GASA-CIR (NCT03812458)
- Testing
- website and brochure
- Where
- Brazil
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Acute Stress Reaction, Acute Stress Disorder
Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)
This study will examine the safety and efficacy of TNX-102 SL to reduce ASR symptoms and behavioral changes among patients presenting to the emergency department (ED) after motor vehicle collision (MVC).
- Conditions
- Acute Stress Reaction, Acute Stress Disorder, Neurocognitive Function, Post-traumatic Stress
- Trial name
- OASIS (NCT06636786)
- Testing
- Cyclobenzaprine HCl
- Where
- 9 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of North Carolina, Chapel Hill
Stress Disorders, Post-Traumatic, Acute Stress Disorder
Post-traumatic Stress Injuries Among Paramedics and Emergency Dispatchers
As part of their work, emergency first responders, such as paramedics and emergency medical dispatchers are exposed daily to traumatic events.
- Conditions
- Stress Disorders, Post-Traumatic, Acute Stress Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT04202042
- Testing
- Psychological first aid, Usual organisational intervention
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal
Stress Disorder - Post-traumatic (Acute)
Prevention of Post-traumatic Stress Disorder by Telephone Based Cognitive Behavioral Therapy
This is a randomized controlled study comparing telephone-based cognitive behavioral therapy (CBT) for recent survivors of traumatic events with Acute Stress Disorder (ASD) or acute PTSD with a waitlist control group.
- Trial name
- NCT00889005
- Testing
- Telephone Based Cognitive Behavioral Therapy
- Where
- Israel
- Volunteers
- 139 people
- Sponsor
- Hadassah Medical Organization
Acute Stress Reaction
Explorative Open Label Study of Efficacy Profile of Neurexan® in Experimental Acute Stress Setting in Healthy Subjects
The purpose of this study is to explore the efficacy of acutely dosed Neurexan using an experimental stress test called the Trier Social Stress Test
- Trial name
- NEUPRO-OL (NCT01703832)
- Testing
- Neurexan®
- Where
- 2 sites in Germany
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Biologische Heilmittel Heel GmbH
Acute Stress Disorder
Micro-Dose, Macro-Impact: Leveraging Psychedelics in Frontline Healthcare Workers During the COVID-19 Pandemic
A retrospective chart review of an open-label trial of low-dose ketamine administered to front-line Healthcare workers who were identified as experiencing acute stress disorder due to the COVID-19 Pandemic.
- Trial name
- NCT04769297
- Testing
- Sublingual Micro-Dose Ketamine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Limbic Medical
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Cognitive Assessment, Working Memory
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor.
- Conditions
- Cognitive Assessment, Working Memory, Executive Function (Cognition), Sustained Attention
- Trial name
- NCT07319117
- Testing
- Skoshify 'Think Tank' Formulation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Acute Disease, Telomere Shortening
Telomere Length in Relation to Acute Stress Response in Critical Care Patients
the investigators studied the impact of severe stress (in this case any event or illness leading to a necessity of critical care) on telomere length.
- Trial name
- NCT03982589
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Rabin Medical Center
Agitated; State, Acute Reaction to Stress, Agitation,Psychomotor
Mindful Melody: Feasibility of Implementing Music Listening on an Inpatient Psychiatric Unit and Its Relation to the Use of As Needed Medications for Acute Agitation
In this quality improvement project, our objectives were to assess the feasibility and effectiveness of using music as an adjunct to or replacement of pharmacological interventions for patient agitation on an inpatient…
- Trial name
- NCT04514432
- Testing
- Music
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Acute Stress Disorder, Post Traumatic Stress Disorder
Internet-delivered Trauma-focused Cognitive-behavioral Therapy as an Early Intervention After Sexual Trauma
The research aims to assess the practicality and implementation aspects, effectiveness, and processes of change related to Condensed Internet-delivered Prolonged Exposure (CIPE) administered as an early trauma focused…
- Trial name
- NCT06502106
- Testing
- Condensed Internet delivered prolonged exposure (CIPE)
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Stress Disorders, Post-Traumatic
Behavioral Treatments for Acute Stress Disorder In Firefighters
This study will develop a treatment for firefighters experiencing symptoms of acute stress disorder (ASD). Effective treatments may reduce immediate symptoms and prevent the development of more chronic conditions, such as…
- Trial name
- NCT00183508
- Testing
- Cognitive behavioral therapy, Psychoeducation
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Boston University
Acute Stress Reaction
Promoting Improved Functioning Among People Experiencing Stressful Situations
The iCOVER intervention was developed to rapidly restore functioning in individuals experiencing an Acute Stress Reaction (ASR). iCOVER is undergoing widespread adoption but has not been tested for efficacy.
- Trial name
- iCOVER (NCT06482567)
- Testing
- iCOVER, Physical Presence with Reassurance
- Where
- 5 sites in United States
- Volunteers
- 450 people
- Sponsor
- University of North Carolina, Chapel Hill
Anxiety, Acute Stress Disorder
Intervention to Decrease Anxiety in Parents of Infants in the Neonatal Intensive Care Unit (NICU)
Infants born premature face numerous medical problems, causing significant anxiety for their parents. Parents experience a range of negative emotions including concern for the health and well being of their fragile infant, guilt…
- Conditions
- Anxiety, Acute Stress Disorder, Posttraumatic Stress Disorder, Depression
- Trial name
- NCT00186472
- Testing
- Brief Cognitive Behavioral Treatment
- Where
- United States
- Sponsor
- Stanford University
Acute Stress Reaction
Neuronal Correlates of Neurexan® Action in Mildly to Moderately Stressed Probands
The purpose of this study is to explore the effect of Neurexan® on the brain response when participants undergo an emotional stressful condition in verum compared to placebo.
- Trial name
- NEURIM (NCT02602275)
- Testing
- Neurexan
- Where
- Germany
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Biologische Heilmittel Heel GmbH
Insomnia, Stress Reaction
Neurexan - a Clinical Trial in Short-Term Insomnia Patients
This clinical study aims to understand the effects of a medication called Neurexan on sleep patterns and stress in people with short-term insomnia.
- Trial name
- NEUREXAN SLEEP (NCT06278077)
- Testing
- Neurexan
- Where
- Germany
- Volunteers
- 81 people
- Sponsor
- Biologische Heilmittel Heel GmbH
Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
Lobectomy is a major, high-risk surgical procedure that in addition to one-lung ventilation (OLV) exerts a potent surgical stress response.
- Conditions
- Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute, Postoperative Pain, Chronic, Infections Postoperative
- Trial name
- NCT05172739
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- University of Crete