Clinical trials: Stress Related Disorder
Workplace Stress, Mental Health
The Effects of Stress & Irregular Shift Hours on First Responders
First Responders are expected to maintain high-performance levels under extreme conditions. However, constant intense workplace stress, physical work demands, and irregular shift hours are taking a severe toll on frontline…
- Conditions
- Workplace Stress, Mental Health, HRV, EEG
- Trial name
- NCT05659277
- Testing
- Workplace Stress and Irregular shift hours
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Endominance
Nicotine Dependence, Nicotine Withdrawal
Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence
The objective of this proposal is to elucidate effects of bupropion SR + varenicline on smoking-cessation related processes in early abstinence using a human laboratory model.
- Trial name
- ChanBan (NCT00749658)
- Testing
- Bupropion, Varenicline
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Trauma, Posttraumatic Stress Disorder
Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot)
One of the most common and widely disseminated trauma treatments is Trauma Focused Cognitive Behavioral Therapy (TF-CBT). TF-CBT is a therapist-led, structured and sequential intervention, with treatment organized around…
- Trial name
- NCT07396935
- Testing
- Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Fear Anxiety, PTSD
Neuroimaging Memories of Fear and Safety in the Human Brain
The purpose of this research is to use functional magnetic resonance imaging (fMRI) to investigate how the brain forms associations between neutral and negative stimuli.
- Trial name
- NCT04975009
- Testing
- Fear conditioning
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Stress Disorder
Evaluating an Expressive Writing Intervention About Communicatively-Restricted Organizational Stressors
This project evaluates the effectiveness of an intervention sought to reduce the physical effects of stress related to those issues that individuals cannot successfully communicate with anyone about.
- Trial name
- NCT01328665
- Testing
- Expressive Writing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Santa Clara University
Post Traumatic Stress Disorder
Implementation of a Post-traumatic Stress Disorder PREvention Program Within the French ARmy
Post-Traumatic Stress Disorder (PTSD) is a mental health condition that's triggered by a terrifying event perceived as a life threatening - either experiencing it or witnessing it.
- Trial name
- PREPAR (NCT05094531)
- Testing
- Primary prevention programm
- Where
- France
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Stress Disorders, Post-Traumatic
Efficacy Study of Mindfulness-Based Exercise for Posttraumatic Stress Disorder (PTSD)
This study will explore the relationship between changes in plasma cortisol and symptom reduction resulting from individuals with posttraumatic stress disorder (PTSD) participating in an 8-week program of mindfulness-based…
- Trial name
- NCT01462045
- Testing
- Mindfulness-based exercise
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Cocaine-Related Disorders, Cocaine Addiction
Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence
This study will, in a sample of cocaine-dependent and healthy control subjects, administer corticorelin and compare dopamine release between groups.
- Conditions
- Cocaine-Related Disorders, Cocaine Addiction, Substance-Related Disorders
- Trial name
- NCT01984177
- Testing
- Corticotropin-Releasing Hormone
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Breast Cancer, Female
Dietary Advanced Glycation End Products, Inflammation and Oxidative Stress in Breast Cancer Patients
Breast cancer is among the most common types of cancer in the world. Factors such as age, reproduction, nutrition, hormonal, and lifestyle factors also play a role in the etiology of breast cancer.
- Trial name
- NCT04716764
- Testing
- 3-Day Food Intake Record
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Mental Health, Depression
Designing a Mobile App to Support Academic Success for Student Veterans
Compared to civilian students in higher education, student Veterans have high rates of mental health disorders (e.g., Depression: 24% vs 12.1%).
- Conditions
- Mental Health, Depression, Post-Traumatic Stress Disorder, Anxiety
- Trial name
- NCT05344092
- Testing
- VetEd Mobile Application
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post-Traumatic, Depressive Disorder, Major
The Effect of Traumatic Childbirth on the Incidence of PTSD and Other Major Postpartum Psychopathology
Determination of incidence and prevalence of PTSD and other types of psychopathology (such as anxiety and affective disorders) after traumatic birth experiences and elucidation of salient risk factors in the local population…
- Trial name
- NCT02370576
- Testing
- rating scale application
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Anxiety
Feasibility Study of a Music and Social Support Intervention for Postnatal Mothers/Infants
This research study aims to assess the feasibility of conducting a full scale trial of Mamas in Harmony, a group music and social support class delivered by a professional musician for mothers and their babies.
- Trial name
- NCT05930990
- Testing
- Mamas in Harmony
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Post Traumatic Stress Disorder, Insomnia
RESILIENT - An Online Multidimensional Treatment to Promote Resilience After a Disaster: Randomized Controlled Trial Protocol
Background. The wildfires on May 1, 2016 in Fort McMurray, Alberta (Canada), destroyed approximately 2,400 homes and buildings and led to massive displacement of approximately 88,000 people.
- Conditions
- Post Traumatic Stress Disorder, Insomnia, Depression
- Trial name
- RESILIENT (NCT04808713)
- Testing
- Treatment
- Where
- Canada
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Laval University
Alcohol Use Disorder, Depression
Project VALOR: Veteran Stress and Wellbeing
This study will examine the efficacy of an internet-based brief intervention designed to reduce risky behavior veterans as the move into their second year post-Army.
- Trial name
- NCT06095817
- Testing
- Internet Delivered Brief Intervention (IDBI)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cornell University
Post-traumatic Stress Disorder
An Advanced Digital Phenotype System Among People Suffering From Post-traumatic Stress Disorder
Psychiatric diagnosis is based mainly on questioning the patient and subjective impression rather than a quantitative assessment.
- Trial name
- NCT03788278
- Testing
- BioBeat
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nadav Goldental
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Acute Traumatic Stress Disorders, Post-Traumatic Stress Disorders
Evaluation of Stress Disorders
The purpose of this study is to examine the short-term consequences of trauma and to determine the effectiveness of the drug sertraline in preventing and treating post-traumatic stress disorder (PTSD) and acute stress disorder…
- Trial name
- NCT00050804
- Testing
- sertraline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Parenting Practices, Self Efficacy
Evaluation Study of Talk Parenting Skills
After development of the prototype Bedtime Routine module of the Talk Parenting program, the investigators will evaluate its feasibility and initial efficacy in a within-subjects pre-post design study.
- Conditions
- Parenting Practices, Self Efficacy, Stress, Child Behavior
- Trial name
- NCT04633434
- Testing
- The Talk Parenting Skill for Alexa
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Violence, Domestic, Stress Related Disorder
Applied Social Neuroscience: the Building Resilience Among Women Project
Intimate partner violence (IPV) is the most common and alarming form of violence against women, affecting up to 25% of all women in Catalonia.
- Conditions
- Violence, Domestic, Stress Related Disorder, Depressive Disorder
- Trial name
- BRAW (NCT03623555)
- Testing
- Trier Social Stress Test, Salivary cortisol
- Where
- Spain
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Ximena Goldberg
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