Clinical trials: Stress Testing
Postoperative Complications (Cardiopulmonary)
Preoperative Exercise Testing and Perioperative Outcomes
The goal of this observational study is to learn whether results from a brief exercise test done before surgery can help identify adults who may be more likely to have problems after moderate- to high-risk noncardiac surgery.
- Trial name
- SAMPO (NCT07519733)
- Testing
- Recruited participants receive preoperative rapid submaximal cardiopulmonary exercise testing within the current risk assessment framework of the pre-surgical evaluation clinic
- Where
- United States
- Volunteers
- 992 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy, Obese
Reference Values of Aerobic Fitness in the Contemporary Paediatric Population
In most pediatric medical conditions, tremendous progress in pediatrics has significantly improved the overall prognosis and transferred the mortality from childhood to adulthood.
- Trial name
- SAIN&NORMES (NCT04876209)
- Where
- France
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Mortality After Major Non Cardiac Surgery
Intraoperative Dobutamine Stress Test With Speckle Tracking to Decrease Postoperative Mortality (ISTMO)
Perioperative adverse cardiovascular events are the leading cause of morbidity and mortality after noncardiac surgery. The implications of perioperative cardiac complications on morbidity and mortality, in-hospital and long-term…
- Trial name
- ISTMO (NCT03365726)
- Testing
- Dobutamine stress test with trans-esophageal echocardiography
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Metabolic Myopathies, Exercise Test
Metabolic Exercise Testing
Exertional symptoms are the hallmarks of metabolic myopathies, supporting the concept of using functional tests when this diagnosis is suspected.
- Conditions
- Metabolic Myopathies, Exercise Test, Myalgia
- Trial name
- RANNOU (NCT02362685)
- Testing
- functional test, matching genotype with phenotype
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Muscle Oxygenation
Intercostal Muscle Oxygenation During Exercise Tests
The aim of our study is to determine the effects of different exercise capacity tests on intercostal muscle oxygenation and to reveal the effect of changing accessory respiratory muscle oxygenation on exercise test success.
- Trial name
- NCT06410638
- Testing
- Six Minute Walking Test, Shuttle walking test
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Sudden Cardiac Death, Sudden Cardiac Arrest
Low QRS Voltages in Young Healthy Individuals and Athletes
There is some limited evidence that reduced size of electrical complexes/traces of the heart on the electrocardiogram (ECG) may be associated with scarring in the heart muscle, which may predispose to serious life-threatening…
- Conditions
- Sudden Cardiac Death, Sudden Cardiac Arrest, Sudden Cardiac Death Due to Cardiac Arrhythmia, Arrhythmogenic Right Ventricular Cardiomyopathy
- Trial name
- NCT05799833
- Testing
- Cardiovascular magnetic resonance scan - 3T scanner (Siemens Vida)
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Mitochondrial Disease, Metabolic Myopathy
GDF-15 as a Biomarker for Mitochondrial Disease
Mitochondrial disorders are a group of inherited disorders causing malfunctional mitochondria. Mitochondria are found in every cell of the body, and the disorders therefore give symptoms from every tissue, especially those with…
- Conditions
- Mitochondrial Disease, Metabolic Myopathy, Muscular Dystrophy
- Trial name
- GDF-15 (NCT02745938)
- Where
- Denmark
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Emotion Regulation
Testing Self-regulation Effects of a 'Smart Toy'
The present experimental study aims to explore the effect of an interactive smart toy on children's stress modulation during a stressful experience compared to a non-interactive prototype.
- Trial name
- NCT03732989
- Testing
- Interactive toy prototype, Non-interactive toy prototype
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University College, London
Newborn, Maternal Voice
The Effect of Maternal Voice and Music Therapy on Pain and Stress During Heel Prick Testing in Newborns
During the adaptation process to the extrauterine environment, healthy newborns face procedures such as hepatitis B vaccination, vitamin K injection, blood sugar monitoring, bilirubin or metabolic disease screening.
- Conditions
- Newborn, Maternal Voice, Music Therapy, Heel Prick Testing
- Trial name
- NCT07773792
- Testing
- Music Therapy, Maternal Voice
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Stress
Assessment of Stress Levels in Consumers Using Ovulation Tests in Order to Conceive
Approximately 150 female volunteers wishing to become pregnant will be recruited via web recruitment from around the UK and randomised 1:1 to receive Clearblue Digital ovulation tests (active arm) or no aid to conception (control…
- Trial name
- NCT01084304
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Arthrogryposis, Craniofacial Abnormalities
Study of Resting and Exercising Body Functioning in Freeman-Sheldon Syndrome and Related Conditions
The hypotheses of the present study of Freeman-Sheldon syndrome (FSS) and related conditions are: (1) that exercise capacity is lower in FSS patients versus normal controls, and the lower exercise capacity is due to changes in…
- Trial name
- FSS-EDICT I (NCT01306994)
- Testing
- Lactate, Glucose, and Adenosine Triphosphate Blood Levels, Physiological Stress Test, Functional Enquiry Form
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)
LETHE-AT: a Personalized Multidomain Lifestyle Intervention for Individuals at Increased Risk of Memory Impairment.
The goal of this clinical trial is to learn whether a hybrid multidomain lifestyle program can prevent cognitive decline and reduce dementia risk in community-dwelling adults in mid- to late life who are at increased risk of…
- Trial name
- LETHE-AT (NCT07376135)
- Testing
- A tailored hybrid multidomain lifestyle intervention group, Self-guided multimodal lifestyle advice group
- Where
- 3 sites in Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Inflammation, Oxidative Stress
An Evaluation of Zinc Status Biomarkers
The purpose of this study is to determine the effect of a moderate decrease in dietary zinc on DNA strand breaks and other cellular zinc biomarkers.
- Trial name
- NCT02861352
- Testing
- Diet zinc
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension
the Application of Cardiopulmonary Exercise Testing in Assessment Outcome of Patients With Pulmonary Hypertension
cardiopulmonary exercise test evaluate patients with pulmonary hypertension before and after medical or balloon pulmonary angioplasty treatment
- Conditions
- Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Arterial Hypertension Associated With Schistosomiasis (Disorder)
- Trial name
- CPETPH (NCT02061787)
- Testing
- balloon pulmonary angioplasty
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Pulmonary Arterial Hypertension
Exercise Capacity Respiratory Muscle Strength Dyspnea and Physical Activity in Pediatric Pulmonary Arterial Hypertension
The primary aim of this study was to evaluate exercise capacity, respiratory muscle strength, pulmonary function, dyspnea and physical activity levels in pediatric PAH patients and compare them with healthy controls.
- Trial name
- NCT05124015
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Gazi University
Near-Infrared Spectroscopy, Iliac Artery Stenosis
NIRS and Exercise Intensity in Patients With FLIA
The research objectives of this project are to increase the understanding of pathophysiology and performance limitations related to sport-related flow limitation in the iliac artery (FLIA) using non-invasive measurement of muscle…
- Conditions
- Near-Infrared Spectroscopy, Iliac Artery Stenosis, Iliac Artery Disease, Iliac Artery Occlusion
- Trial name
- NCT05229250
- Testing
- Cycling test, Occlusion tests, NIRS during cycling
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Stress
Copeptin During a Standardized Psychological Stress Test
The aim of the PsyCo Study is to determine whether psychological Stress has an influence on copeptin levels.
- Trial name
- PsyCo (NCT01866137)
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Anxiety, Bowel Habits
Test Anxiety on Bowel Health and Constipation in Students
This observational cross-sectional study aims to examine the relationship between test anxiety, bowel health, and constipation in university students.
- Conditions
- Anxiety, Bowel Habits, Constipation
- Trial name
- NCT07654959
- Testing
- Observational assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Anxiety, Depression
Project THINK: Trial of a Brief Cognitive Restructuring Intervention
This project will involve testing a brief (~30 minute) digital intervention aimed at teaching youth the evidence-based strategy of changing unhelpful thoughts (i.e., cognitive restructuring).
- Conditions
- Anxiety, Depression, Stress
- Trial name
- NCT05720741
- Testing
- Project THINK, Project SHARE
- Where
- United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- Harvard University