Clinical trials: Stress Testing
Echocardiography, Stress, Reference Values
Echocardiographic Assessment of the Right Ventricle in Healthy Subjects During Stress Test in the Mexican Population
The echocardiographic indices of the right ventricle function vary significantly with demographic and anthropometric of each population factors and are associated with poor prognosis in several cardiovascular diseases.
- Trial name
- ECORVStressMx (NCT04286854)
- Testing
- Stress echocardiography with semi-supine bicycle
- Where
- Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Miguel Ayala León
Exercise, Respiratory Rate
Validation of Respiratory Rate and Heart Rate Measurements by Capaciflectors Placed in Four Locations on the Chest
In a collaborative project between University Hospital Southampton NHS Trust and the University of Southampton, the investigators have developed a wearable, mobile, non invasive, low-cost, continuous respiratory rate monitor…
- Conditions
- Exercise, Respiratory Rate, Heart Rate
- Trial name
- NCT03832205
- Testing
- Capaciflector monitoring
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Muscle Damage, Muscle Soreness
RubusElite Efficacy Testing of a Novel High Protein, Berry Polyphenol Enriched Dairy Beverage
The RubusElite project is a multi-disciplinary project combining expertise in exercise science, nutrition, biochemistry, microbiology and food science across three institutions: University College Cork, Waterford Institute of…
- Conditions
- Muscle Damage, Muscle Soreness, Exercise Performance, Gut Microbiome
- Trial name
- NCT05463835
- Testing
- RubusElite, 'Protein rich' dairy beverage, 'Low Protein' dairy beverage
- Where
- Ireland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University College Cork
Stress, Mental Stress
Influence of Melatonin on Cardiovascular and Thermoregulatory Responses to Stress
This study aims to evaluate the influence of acute oral melatonin supplementation on cardiovascular and skin temperature responses to mental stress.
- Trial name
- NCT07138443
- Testing
- Melatonin 3 MG Oral Tablet
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Baylor University
Cardiovascular Diseases, Cardiovascular Abnormalities
Cardiovascular Risk Factors on Electrocardiographically and Hemodynamics Responses to Treadmill Exercise Test
The goal of this observational cross-sectional study is to analyze the effect of cardiovascular risk factors in healthy and asymptomatic populations.
- Conditions
- Cardiovascular Diseases, Cardiovascular Abnormalities, Healthy
- Trial name
- ERGO-RISC (NCT05987891)
- Testing
- Treadmill exercise stress test
- Where
- Brazil
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Simple Obesity
Nutritional Video Intervention Using Mindfulness-based Principles
The purpose of this study is to access the acceptability and potential utility of nutritional intervention videos in 1) changing knowledge and attitudes about healthy eating, 2) improving healthy food shopping practices, and 3)…
- Trial name
- NCT02494661
- Testing
- Healthy Cart and Stress Management Videos, Healthy Cart Video
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Heart Failure
Non-invasive Ventilation in Patients With Cardiac Heart Failure
Patients with heart failure (HF) have a reduced exercise tolerance as the main result of the disease. This exercise intolerance is due to heart conditions, but also to dysfunction of the respiratory and peripheral muscles.
- Trial name
- NCT05433610
- Testing
- Non-invasive Ventilation
- Where
- Argentina
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Chronic Kidney Failure
Furosemide and Creatinine Tubular Stress Test in Order to Measure Proximal Tubule Residual Function
This is a two phase study. The first part will take place at the National Institute of Cardiology in Mexico, the second phase will be made in collaboration with the University of California San Diego and University of Minnesota.
- Trial name
- NCT05105009
- Testing
- Furosemide Injection, Creatinine Powder, Iohexol
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Adverse Childhood Experience, Endothelial Function (FMD)
Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity
Adverse childhood experiences (ACEs) represent highly stressful events in the first 18 years of life that include abuse, neglect, and household and community-level dysfunction.
- Conditions
- Adverse Childhood Experience, Endothelial Function (FMD), Endothelial Injury, Mitochondrial Function
- Trial name
- PROMISE (NCT07244809)
- Testing
- Mitoquinone mesylate (MitoQ)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Stress Urinary Incontinence
Standardization of Cough Stress Test
This is a multicenter, prospective, randomized comparative study in which patients are randomized to one of four different bladder volumes and a Cough Stress Test (CST) is performed in both the standing and sitting positions.
- Trial name
- NCT02742584
- Testing
- Cough Stress Test
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Stress Incontinence, Female, Overactive Bladder
Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing
In this pilot study the investigators attempt to answer the question, does mindfulness exercises before urodynamic testing reduce patient's perception of anxiety or pain?
- Conditions
- Stress Incontinence, Female, Overactive Bladder, Lower Urinary Tract Symptoms
- Trial name
- NCT03625843
- Testing
- Mindfulness exercises
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- San Antonio Uniformed Services Health Education Consortium
Caregiver Burden, Self Efficacy
An Online Ecoaching RCT Intervention for Carers: Enhancing Wellbeing and Resilience Through Self-Help Strategies
The goal of this three-armed, double-blind randomized controlled trial (RCT) is to compare the effectiveness of an online self-help eCoaching intervention designed for caregivers.
- Conditions
- Caregiver Burden, Self Efficacy, Quality of Life, Anxiety Depression
- Trial name
- NCT06604481
- Testing
- eCoaching for Caregivers of Older Adults, eCoaching (need specific) for Caregivers of Older Adults, Control Intervention for Caregivers of Older Adults
- Where
- Hong Kong
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Midlife Obese Adults With Cognitive Decline
Weight Reduction and Cognitive Health: Pilot Study Testing a Prolonged Testing Prolonged Fasting Among Obese, Stressed Mid-life Adults
Using a randomized controlled trial (RCT) design, we will test feasibility and outcomes following an remotely delivered, nationwide 8-week prolonged nightly fasting (PNF) intervention compared to an health education control (HEC)…
- Trial name
- GetSmart (NCT05388318)
- Testing
- Prolonged nightly fasting, Health Education Control
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Fontan Palliation
Upright Versus Supine Exercise Testing in Fontan-palliated Patients
Fontan-palliated patients comprise an interesting group of single-ventricle patients who are dependent upon passive return of blood from the body to the lungs.
- Trial name
- NCT00633815
- Testing
- Supine positioning, Upright positioning
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hypertension
Endothelin Receptor Function and Acute Stress
Our bodies respond differently to stress. Animal studies by the investigators have found that endothelin-1 plays a role in regulating blood pressure in response to stress.
- Trial name
- End-Stress (NCT02116335)
- Testing
- Bosentan
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Augusta University
Metabolic Myopathy
Metabolomic Approach During Exercise Testing in Myalgia Induced by eXercise
Metabolic myopathies form a group of pathologies related to a deficit of muscle energy production (enzymatic deficit) by disorder of the metabolism of carbohydrates, lipids, purines, or mitochondrial involvement related to…
- Trial name
- Matmix (NCT05413681)
- Testing
- a supra-maximal exercise test on a cycloergometer., handgrip muscle activity test.
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Cardiorespiratory Fitness, Metabolic Health
Validation of a Novel Incremental Step Test for Assessment of Cardiopulmonary Fitness and Ventilatory Thresholds in Adults
The purpose of this single-group diagnostic validation and test-retest reliability study is to determine whether a novel Incremental Step Test (IST) can accurately assess cardiorespiratory fitness and ventilatory thresholds in…
- Conditions
- Cardiorespiratory Fitness, Metabolic Health, Cardiac Function, Pulmonary Function
- Trial name
- VALID-IST (NCT07829003)
- Testing
- Cardiopulmonary Exercise Test, Incremental Step Test
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Heriot-Watt University
Cardiometabolic Risk, Abdominal Obesity
Synergistic Innovative Functional Food Concepts to Neutralize Inflammation for Cardiometabolic Risk Prevention
The aim of the study is to evaluate the synergistic effects of daily consumption of food products fortified with bioactive components (fibres, polyphenols, omega-3, Slow Digestible Starch) for 9 weeks, compared to the daily…
- Trial name
- SINFONI (NCT04190706)
- Testing
- bioactive components fortified food products intake (biscuits and cookies), control food products intake (biscuits and cookies)
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Stress
Project Movement/Daily Move Feasibility
The purpose of this study is to test the feasibility (acceptability and demand) of the Daily Move in a diverse sample of US adults.
- Trial name
- NCT05248711
- Testing
- Calm Daily Move
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Calm.com, Inc.
Exercise, Exercise Test
Multi-level Molecular Profiling of Peak Performance in Endurance Sports
Physical activity triggers complex molecular responses, including changes in immune-, stress-, and metabolic pathways. For example, autophagy is essential for energy and cellular homeostasis through protein catabolism, and…
- Conditions
- Exercise, Exercise Test, Physical Fitness, Healthy
- Trial name
- MSSA (NCT05359744)
- Testing
- Performance testing
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University