Clinical trials: Stress Urinary Incontinence (SUI)
Stress Urinary Incontinence (SUI)
A Study to Assess the Safety and Effectiveness of the UrOActive® Artificial Urinary sPHincter (AUS)
Prospective, multicenter, single-arm study
- Trial name
- SOPHIA2 (NCT06968741)
- Testing
- Artificial Urinary Sphincter (AUS)
- Where
- 21 sites in United States, France
- Volunteers
- 140 people
- Sponsor
- UroMems SAS
Urinary Incontinence, Mixed Urinary Incontinence
Comparing the Effect of Two Types of Pelvic Floor Muscle Stimulation Devices to Improve Symptoms of Urinary Incontinence in Women.
This randomized, parallel-group, non-inferiority clinical trial will compare electromagnetic chair therapy with standard electrostimulation combined with biofeedback in 58 adult women with mixed urinary incontinence.
- Conditions
- Urinary Incontinence, Mixed Urinary Incontinence, Urinary Incontinence (UI), Stress Urinary Incontinence (SUI)
- Trial name
- ESEMS (NCT07792031)
- Testing
- Electromagnetic chair therapy, Electrical stimulation therapy
- Where
- 2 sites in Argentina
- Volunteers
- 58 people
- Sponsor
- Espacio Gaspar Clinic
Stress Urinary Incontinence (SUI)
The Effects of Expiratory Muscle Strength Training in Women With Stress Urinary Incontinence
The aim of this study is to investigate the effects of expiratory muscle strength training in addition to pelvic floor muscle training in women with stress urinary incontinence.
- Trial name
- NCT07693920
- Testing
- Pelvic Floor Muscle Training, Expiratory muscle strength training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Mustafa Kemal University
Stress Urinary Incontinence (SUI)
Pelvic Floor Muscle Exercise and Progressive Muscle Relaxation for Stress Urinary Incontinence
Stress urinary incontinence (SUI) is a common condition in women that causes involuntary urine leakage during activities such as coughing, sneezing, laughing, or exercising.
- Trial name
- NCT07762391
- Testing
- Pelvic Floor Muscle Exercise, Progressive Muscle Relaxation (PMR), Combined Pelvic Floor Muscle Exercise and Progressive Muscle Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Benign Prostatic Hyperplasia, Stress Urinary Incontinence (SUI)
Optimization of Surgical Treatment Pathways for BPH Based on Real-World Data
Benign prostatic hyperplasia is a noncancerous enlargement of the prostate that can cause difficulty urinating. Holmium laser enucleation of the prostate (HoLEP) uses a laser to remove prostate tissue blocking urine flow.
- Trial name
- NCT07872085
- Testing
- Conventional HoLEP Without Apical Pre-disconnection, HoLEP With Fixed 12 O'clock Apical Pre-disconnection, HoLEP With MRI-Guided Individualized Apical Pre-disconnection
- Where
- China
- Volunteers
- 153 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Stress Urinary Incontinence (SUI)
Motor Imagery-Assisted Pelvic Floor Muscle Training for Stress Urinary Incontinence in Postmenopausal Women
This study will evaluate whether adding mental rehearsal of pelvic floor muscle contractions to pelvic floor muscle training improves stress urinary incontinence in postmenopausal women.
- Trial name
- NCT07853755
- Testing
- Pelvic Floor Muscle Training, Pelvic-Floor-Specific Kinesthetic Motor Imagery, Dominant-Hand Kinesthetic Motor Imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI)
Vaginal Prasterone Versus Estriol in Women With Pelvic Floor Disorders
This prospective, non-randomized comparative study evaluated the effects of short-term vaginal treatment with prasterone or estriol in women with pelvic floor disorders who were awaiting urogynecological surgery.
- Trial name
- NCT07854873
- Testing
- Prasterone (DHEA), Estriol
- Where
- Poland
- Volunteers
- 74 people
- Sponsor
- Poznan University of Medical Sciences
Urinary Incontinence (UI), Laser Therapy
Laser Therapy and Pelvic Floor Muscle Training for Stress Urinary Incontinence
The aim of this study was to investigate the effects of Pelvic Floor Muscle Training (PFMT) in addition to high-intensity laser therapy (HILT) on pelvic floor dysfunction, sexual dysfunction, and quality of life in women with…
- Conditions
- Urinary Incontinence (UI), Laser Therapy, Stress Urinary Incontinence (SUI), Pelvic Floor Muscle Exercise
- Trial name
- NCT07319247
- Testing
- PFME and Laser Therapy, Plasebo Laser, PFME
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Necmettin Erbakan University
Radical Prostatectomy, Stress Urinary Incontinence (SUI)
Pivotal Study of Voro Urologic Scaffold
The objective of this study is to compare safety and effectiveness of the Voro Urologic Scaffold in adult men undergoing robotic assisted radical prostatectomy as compared to control arm.
- Trial name
- ARID II (NCT06873581)
- Testing
- Voro Urologic Scaffold
- Where
- 19 sites in United States
- Volunteers
- 266 people
- Sponsor
- Levee Medical, Inc.
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI)
Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery
Suzetrigine is a selective NaV1.8 inhibitor that provides peripheral analgesia without opioid-related CNS effects. This single-center stepped-wedge randomized clinical trial evaluates whether a suzetrigine-based postoperative…
- Conditions
- Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI), Postoperative Pain
- Trial name
- NCT07600697
- Testing
- Suzetrigine, Opioid Analgesics (Tramadol or Oxycodone), Scheduled Acetaminophen and Ibuprofen
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Stress Urinary Incontinence (SUI)
The Effect of Different Delivery Positions on Pelvic Floor Function.
This study is a prospective, multicenter, randomized controlled trial. Baseline data will be collected from eligible subjects recruited during the third trimester of pregnancy.
- Trial name
- NCT07081321
- Testing
- Lithotomy position, Lateral Position, Upright Position
- Where
- China
- Volunteers
- 1,992 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Stress Urinary Incontinence (SUI)
Long-term Outcomes of Urethral Ligament Plication and Transvaginal Tape Surgery
In the treatment of urinary incontinence caused by coughing, sneezing, or heavy lifting, the investigators will perform urinary tract tightening surgery, both with and without a sling, to address the relaxed urinary tract.
- Trial name
- TVT/ULP (NCT07484321)
- Testing
- Transvaginal tape, Urethral ligament plication
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Sanliurfa Education and Research Hospital
Stress Urinary Incontinence (SUI), Dynamic Neuromuscular Stabilization
Dynamic Neuromuscular Stabilization Exercises in Women With Urinary Incontinence
Stress urinary incontinence (SUI) is defined by the International Continence Society as the complaint of involuntary leakage of urine during physical exertion, including sports activities, or during sneezing or coughing.
- Conditions
- Stress Urinary Incontinence (SUI), Dynamic Neuromuscular Stabilization, Pelvic Floor Muscle Training, Urinary Symptoms
- Trial name
- NCT07009249
- Testing
- Pelvic floor muscle training, Dynamic neuromuscular stabilization
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Izmir University of Economics
Stress Urinary Incontinence (SUI), Stress Urinary Incontinence in Women
Effect of Hypo-pressive Exercises and Pelvic Floor Muscle Training in Postpartum Stress Urinary Incontinence Women
Postpartum stress urinary incontinence is a widespread condition characterized by involuntary loss of urine during physical exertion, such as sneezing, coughing, or lifting heavy weights.
- Trial name
- SUI PFMT HE (NCT07322328)
- Testing
- hypo-pressive exercise, pelvic floor muscle training
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Stress Urinary Incontinence (SUI), Transobturator Tape
Hybrid Transobturator Tape Versus Conventional Synthetic Tape for Stress Urinary Incontinence
This randomized controlled trial compares the safety, efficacy, and impact on female sexual function of a novel hybrid transobturator tape (combining an autologous rectus fascia strip with a polypropylene mesh) versus standard…
- Conditions
- Stress Urinary Incontinence (SUI), Transobturator Tape, Hybrid Sling, Female Sexual Function
- Trial name
- NCT07762300
- Testing
- Standard Synthetic Transobturator Tape (TOT), Hybrid Transobturator Tape Sling
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University
Stress Urinary Incontinence (SUI)
The Effect of Periurethral Injection of Platelet Rich Plasma Versus Mid-urethral Sling in Treatment of Stress Urinary Incontinence
this study used to compare efficacy between platelet rich plasma periurethral injection versus mid urethral sling ( trans obturator tape ) in treatment of stress urinary incontinence
- Trial name
- NCT07550426
- Testing
- Platelet Rich Plasma, Mid urethral sling ( trans obturator tape)
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Stress Urinary Incontinence (SUI)
A Study of Two Versions of the Uresta Pessary Handle for Women With Stress Urinary Incontinence
The goal of this clinical trial is to learn if a new handle design for the uresta pessary works better than the current handle design for women when they are using the pessary.
- Trial name
- NCT07706491
- Testing
- pessary handle
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Resilia Inc.
Stress Urinary Incontinence (SUI)
Differences in Pelvic Floor Motion Level Among Chinese Women and Construction of an Assessment System
The purpose of this study is to integrate millimeter-wave radar technology to investigate the dynamic movement characteristics of the pelvic floor muscles in patients with different Body Mass Index (BMI) and stress urinary…
- Trial name
- NCT07608146
- Where
- 20 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI)
Development and Validation of a Risk Prediction Model for De Novo Stress Urinary Incontinence After Pelvic Floor Reconstruction Surgery
This observational study aims to develop a predictive model for the occurrence of new-onset stress urinary incontinence (SUI) after pelvic organ prolapse (POP) repair surgery in women.
- Trial name
- NCT07601282
- Testing
- Telephone follow-up
- Where
- China
- Volunteers
- 382 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Mixed Urinary Incontinence, Stress Urinary Incontinence (SUI)
Augmenting Urinary Reflex Activity Study 4 (Including eXtended Indications)
Exploratory safety and feasibility study of personalized adaptive pudendal neuromodulation for mixed urinary incontinence and extended indications using an implanted (Picostim™ II) system.
- Conditions
- Mixed Urinary Incontinence, Stress Urinary Incontinence (SUI), Chronic Pelvic Pain, Urge Urinary Incontinence
- Trial name
- AURA-4X (NCT06885931)
- Testing
- Pudendal neuromodulation
- Where
- 7 sites in Belgium, Netherlands and 1 more
- Volunteers
- 86 people
- Sponsor
- Amber Therapeutics Ltd