Clinical trials: Stress Urinary Incontinence (SUI), open to volunteers
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI)
Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery
Suzetrigine is a selective NaV1.8 inhibitor that provides peripheral analgesia without opioid-related CNS effects. This single-center stepped-wedge randomized clinical trial evaluates whether a suzetrigine-based postoperative…
- Conditions
- Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI), Postoperative Pain
- Trial name
- NCT07600697
- Testing
- Suzetrigine, Opioid Analgesics (Tramadol or Oxycodone), Scheduled Acetaminophen and Ibuprofen
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Urinary Incontinence , Stress
Pilot Study of the ARTUS® Artificial Urinary Sphincter on Women
The subjects will be implanted with the ARTUS® medical device and then be followed up to 2 years post-implantation, with the primary endpoints measured at 3-month post-implantation.
- Trial name
- SPHIN-X (NCT07641218)
- Testing
- Artificial Urinary Sphincter ARTUS
- Where
- 2 sites in France
- Volunteers
- 6 people
- Sponsor
- Myopowers Medical Technologies France SAS
Stress Urinary Incontinence (SUI)
Long-term Evaluation of the I-STOP Sling in Stress Urinary Incontinence Treatment
Evaluate quality of life and rate of reoperation after implantation of the I-STOP sling for stress urinary incontinence
- Trial name
- VIGI-ISTOP (NCT06665698)
- Volunteers
- 500 people
- Sponsor
- DILO Medical
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI)
Development and Validation of a Risk Prediction Model for De Novo Stress Urinary Incontinence After Pelvic Floor Reconstruction Surgery
This observational study aims to develop a predictive model for the occurrence of new-onset stress urinary incontinence (SUI) after pelvic organ prolapse (POP) repair surgery in women.
- Trial name
- NCT07601282
- Testing
- Telephone follow-up
- Where
- China
- Volunteers
- 382 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Stress Urinary Incontinence, Female Urinary Incontinence
Effect of Modified Mesh on Surgical Success in Transobturator Tape Surgery
This study is a single-blind, randomized controlled trial evaluating whether changing the width of the surgical tape (mesh) used in transobturator tape (TOT) surgery improves treatment results in women with stress urinary…
- Conditions
- Stress Urinary Incontinence, Female Urinary Incontinence, Pelvic Floor Dysfunction
- Trial name
- MOTOT (NCT06924450)
- Testing
- 1.2 cm Mesh TOT, 1.0 cm Mesh TOT
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Izzet Celegen
Stress Urinary Incontinence (SUI)
The Impact of Breathing Training on PPSUI: A Randomized Controlled Trial
Clinical Trial This clinical trial aims to investigate the clinical therapeutic effects of breathing training on postpartum stress urinary incontinence (PPSUI).
- Trial name
- PPSUI (NCT06623617)
- Testing
- Breathing training, control group
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Jie Li
Urinary Incontinence, Mixed Urinary Incontinence
Comparing the Effect of Two Types of Pelvic Floor Muscle Stimulation Devices to Improve Symptoms of Urinary Incontinence in Women.
This randomized, parallel-group, non-inferiority clinical trial will compare electromagnetic chair therapy with standard electrostimulation combined with biofeedback in 58 adult women with mixed urinary incontinence.
- Conditions
- Urinary Incontinence, Mixed Urinary Incontinence, Urinary Incontinence (UI), Stress Urinary Incontinence (SUI)
- Trial name
- ESEMS (NCT07792031)
- Testing
- Electromagnetic chair therapy, Electrical stimulation therapy
- Where
- 2 sites in Argentina
- Volunteers
- 58 people
- Sponsor
- Espacio Gaspar Clinic
Stress Urinary Incontinence, Pelvic Organ Prolapse
Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry
The objective of this post market, clinical registry is to evaluate the performance of the products of the TVT family of products or vaginal vault or uterine prolapse repair (with laparotomic or laparoscopic approach including…
- Trial name
- NCT04829175
- Testing
- Intervention
- Where
- 10 sites in United States, Austria and 5 more
- Volunteers
- 1,000 people
- Sponsor
- Ethicon, Inc.
Stress Urinary Incontinence (SUI)
Stress Urinary Incontinence for Female Patients (CGM MUIT-2301)
This study is a multicenter, prospective, randomized, double-blind, sham-controlled clinical trial conducted in female patients with stress urinary incontinence.
- Trial name
- NCT07440927
- Testing
- Ceragem Innerfit medi-tech
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Ceragem Clinical Inc.
Urinary Incontinence, Urinary Incontinence,Stress
Adjustable Continence Therapy (ACT) for the Treatment of Female SUI
A prospective, single arm, non-randomized, multicenter, prospective case-series trial. The purpose of this trial is to demonstrate the safety and effectiveness of using the Adjustable Continence Therapy (ACT) to provide a…
- Trial name
- NCT04248283
- Testing
- Adjustable Continence Therapy for Women (ACT)
- Where
- 8 sites in United States, France
- Volunteers
- 167 people
- Sponsor
- Uromedica
Stress Urinary Incontinence (SUI)
CHM for Female Stress Urinary Incontinence
This single-arm, open-label pilot clinical trial will test the hypothesis that S-2196, a Chinese herbal medicine formula, will show efficacy and safety in alleviating the amount and frequency of urinary incontinence in female…
- Trial name
- NCT06855602
- Testing
- Chinese herbal medicine formula (S-2196)
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- Hong Kong Baptist University
Stress Urinary Incontinence (SUI), Transobturator Tape
Hybrid Transobturator Tape Versus Conventional Synthetic Tape for Stress Urinary Incontinence
This randomized controlled trial compares the safety, efficacy, and impact on female sexual function of a novel hybrid transobturator tape (combining an autologous rectus fascia strip with a polypropylene mesh) versus standard…
- Conditions
- Stress Urinary Incontinence (SUI), Transobturator Tape, Hybrid Sling, Female Sexual Function
- Trial name
- NCT07762300
- Testing
- Standard Synthetic Transobturator Tape (TOT), Hybrid Transobturator Tape Sling
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University
Urinary Incontinence, Urinary Incontinence, Stress
Elastographic Assessment of Suburethral Tissue in Continent and Incontinent Women
Strain elastography (SE) will be utilized as a non-invasive imaging technique to evaluate tissue elasticity and biomechanical properties in women with stress urinary incontinence (SUI) and in continent controls.
- Conditions
- Urinary Incontinence, Urinary Incontinence, Stress, Urinary Incontinence (UI), Urinary Bladder, Overactive
- Trial name
- SE-inc1 (NCT06933407)
- Testing
- Strain Elastography
- Where
- Hungary
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Szeged University