Clinical trials: Stress and Anxiety
Childhood Anxiety Disorder, Childhood Depression
Brief Internet-delivered Intervention for Children and Adolescents With Anxiety and Depression Symptoms
Investigators developed a brief standardized internet-delivered cognitive-behavioral program for treating anxious and depressive symptoms in children and adolescents in the context of COVID-19 pandemics in Brazil.
- Trial name
- NCT05139433
- Testing
- Telepsychotherapy, Psychoeducational Videos
- Where
- Brazil
- Volunteers
- 280 people
- Sponsor
- University of Sao Paulo
Anxiety Disorder
Cipralex® for Anxiety Disorders in Adolescents
The primary objective is to examine whether Cipralex® is effective and safe in the treatment of anxiety disorders in youth. The secondary objective is to identify changes in arousal and stress response from pre- to post-treatment…
- Trial name
- CAP-E (NCT01293838)
- Testing
- Cipralex®
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Ottawa
Anxiety Disorders and Symptoms Depressive Symptoms, Risk Factors (Rejection, Bullying/Cyberbullying, Addictions, Healthy Lifestyle Habits, Exam Stress Management, Ecoanxiety, Expressed Emotion)
Selective Prevention Transdiagnostic Intervention for At-risk Adolescents With Booster Sessions. (PROCARE+ 2.0)
Emotional disorders such as anxiety and depression are significantly underdiagnosed and undertreated, even though they are some of the most prevalent mental health conditions, especially among young individuals.
- Trial name
- NCT06185049
- Testing
- PROCARE+ (Core intervention with add-on modules) and two booster sessions., PROCARE+ (Core intervention with add-on modules) and one booster session, PROCARE+ (Core intervention with add-on modules) without booster sessions.
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Jaén
Caregivers
Cereset Research for Caregivers
Caregivers experience high levels of prolonged stress that can lead to chronic problems with health, including increased risk of cardiovascular disease that is linked to autonomic dysregulation.
- Trial name
- NCT05209438
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Post Traumatic Stress Disorder, Anxiety
PTSD Symptoms Among Health Workers and Public Service Providers After the COVID-19 Outbreak: A 3 Month Follow up
The aim of this study is to investigate the levels of trauma and mental symptoms (i.e., depression and anxiety) among health workers and public service providers 3 months after (T2) the strict social distancing government…
- Conditions
- Post Traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT04442243
- Volunteers
- 889 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Mental Health Wellness 1
The Effects of Trauma-sensitive Yoga and Tai Chi on Mental Health
A three-arm randomized control trial design was used to test the effectiveness of (1) Chen Style Tai Chi (TC) and talk therapy; (2) Trauma-Sensitive Yoga and talk therapy in comparison to (3) talk therapy only (control group) on…
- Trial name
- TSY/TC (NCT04754009)
- Testing
- Trauma-Sensitive Yoga + TAU, Chen Style Tai Chi + TAU, Treatment as Usual
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Anxiety, Caregiver Burden
Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With ADRD
The purpose of the study is to test if Acceptance and Commitment Therapy (ACT), a behavioral intervention designed to increase psychological flexibility in the face of challenges, reduces anxiety associated psychological distress…
- Trial name
- (TACTICs) (NCT04780178)
- Testing
- Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults with Alzheimer's Disease and Related Dementias
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Anxiety, Stress
The Effect of Music Therapy and Progressive Muscle Relaxation Exercise on Anxiety Before the First Clinical Practice
This study was carried out to evaluate the effect of music therapy and progressive muscle relaxation exercise on the state and trait anxiety levels before their first clinical practice in nursing students.
- Trial name
- NCT04540172
- Testing
- Music Therapy, Progressive Muscle Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Fatigue, Cardiopulmonary Arrest
Post-Coronavirus Disease of 2019 (COVID-19) Rehabilitation Clinics in Saudi Arabia
This intervention study aims to evaluate the before and after changes in physical fitness, cardiorespiratory status, exercise capacity, fatigue, anxiety, dyspnea, psychoemotional conditions, and quality of life through 3 sessions…
- Conditions
- Fatigue, Cardiopulmonary Arrest, Physical Inactivity, Muscle Weakness
- Trial name
- NCT05799534
- Testing
- Physical Therapy Rehabilitation
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Majmaah University
Post-Traumatic Stress Disorder
Bringing What Works to Youth in Corrections: A Trauma Intervention
Youth with mental illnesses are disproportionately represented in juvenile correctional facilities and limited evidence exists about effective treatments in this setting.
- Trial name
- NCT01560728
- Testing
- Trauma-Focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States
- Volunteers
- 57 people
- Sponsor
- University of Texas at Austin
Perceived Stress, Anxiety Level
The Effect of Mandala Coloring Applied to Caregivers Caring for Palliative Care Patients on Perceived Stress, Anxiety Level, and Quality of Life
The word palliative comes from the Latin word "pallium" meaning "cover". The aim of palliative care is not to eliminate the cause of the disease; to alleviate the negative effects of the disease.
- Conditions
- Perceived Stress, Anxiety Level, Quality of Life
- Trial name
- NCT05847231
- Testing
- Perceived Stress, Mandala application
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Anxiety, Anxiety Disorders
A Feasibility Study of Nature-based Health Interventions for People With Mild to Moderate Anxiety, Depression and Stress
Background and aimThe increased burden on mental health both globally and nationally is a serious challenge that requires attention and action from healthcare professionals, politicians, and decision-makers.
- Conditions
- Anxiety, Anxiety Disorders, Depression - Major Depressive Disorder, Depressive Disorder
- Trial name
- NCT06981000
- Testing
- Locally adapted nature-based health intervention
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Copenhagen
Parenting Self-efficacy, Postpartum Anxiety
Essential Coaching Postpartum: Evaluating a Parent-focused Postpartum Text Message Program in Nova Scotia
The transition to parenthood is often an exciting yet hard period for parents. In the first year after a new baby, many parents feel less confident, have more anxiety and depression, and feel more isolated and alone.
- Conditions
- Parenting Self-efficacy, Postpartum Anxiety, Postpartum Depression (PPD), Postpartum Stress
- Trial name
- NCT06996067
- Testing
- Essential Coaching Postpartum
- Where
- Canada
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Post-Traumatic Stress Disorder
Virtual Reality (VR) Therapy for Post-Traumatic Stress Disorder (PTSD)
It is proposed that using Virtual Reality as part of therapy will result in improvements in Post Traumatic Stress Disorder for Service Members with PTSD related to service in Iraq and/or Afghanistan.
- Trial name
- NCT00992953
- Testing
- Treatment as Usual, Virtual Reality Exposure with Stimulus Control
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- Office of Naval Research (ONR)
Anxiety, Assisted Reproductive Treatments
Virtual Reality for Anxiety Relief in Infertile Women
This study examines the impact of virtual reality (VR) applications on anxiety levels before and after embryo transfer procedures.
- Conditions
- Anxiety, Assisted Reproductive Treatments, Women, VR
- Trial name
- NCT07020975
- Testing
- VR Glasses
- Where
- Cyprus
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cyprus Aydin University
Impulsive Behavior, Impulse Disorders
Clinical Response of Impulsivity After Brain Stimulation in Parkinson's Disease
The objective of this prospective observational cohort study is to answer the following clinically important questions: 1. In patients with a pre-operative history of ICBs, what is the likelihood of improvement or deterioration…
- Conditions
- Impulsive Behavior, Impulse Disorders, Gambling, Pathological, Eating, Binge
- Trial name
- CRIPS (NCT04811807)
- Testing
- Subthalamic Nucleaus Deep brain stimulation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King's College London
Affect (Mental Function), Sleep
Fibre and Mental Wellbeing Feasibility Trial
This feasibility study will explore whether adding an extra 10 grams of fibre to participants' daily diet for two weeks would improve their mental health and wellbeing.
- Conditions
- Affect (Mental Function), Sleep, Anxiety, Stress
- Trial name
- NCT06899607
- Testing
- Fibre arm
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Anxiety Disorders, Generalized Anxiety Disorder
Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli
This study will evaluate the effects of Mindfulness-Based Stress Reduction (MBSR) on physiological reactivity. This study will focus on individuals with anxiety who will participate in an 8-week MBSR class.
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT03206437
- Testing
- Mindfulness-Based Stress Reduction, Waitlist
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Georgetown University
PTSD, Stress Disorders, Post - Traumatic
Innovative Delivery of Evidence Based Psychotherapy to Women With Military Sexual Trauma
The purpose of this study is to determine whether a scientifically validated treatment for Posttraumatic Stress Disorder (PTSD) called Prolonged Exposure (PE) can be delivered effectively to Veterans with Military Sexual Trauma…
- Conditions
- PTSD, Stress Disorders, Post - Traumatic, Anxiety Disorders, Mental Disorders
- Trial name
- NCT02417025
- Testing
- PE
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Medical University of South Carolina
Health College Students
Effects of VR Tai Chi Intervention on Physical Fitness, Anxiety, Depression and Stress Among College Students in Henan, China
Research indicates a substantial increase in the rates of anxiety, depression and stress among college students (Roy, Biswas, \& Sharma, 2025).
- Trial name
- NCT07854821
- Testing
- Virtual Reality-Assisted Tai Chi Training
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Xin Liu
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