Clinical trials: Stress-Related Disorders
Posttraumatic Stress Disorders, Dissociative Identity Disorder
Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect
This study aims to evaluate the neurobiological basis of traumatic dissociation in a cross-diagnostic sample of women who have histories of childhood abuse and neglect.
- Trial name
- NCT02757339
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Post Traumatic Stress Disorder
Technology-Based Tools to Enhance Quality of Care in Mental Health Treatment
Nearly 9 million U.S. children (1 in 8) meet criteria for at least one mental health disorder at any point in time. Effective treatments exist for these disorders, but children and families who seek services rarely receive them…
- Trial name
- NCT01915160
- Testing
- eTF-CBT, TF-CBT
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Posttraumatic Stress Disorder
Fear Potentiation and Fear Inhibition in Posttraumatic Stress Disorder
The current study will investigate the ability of people with and without fear symptoms after trauma to inhibit fear in an experimental situation.
- Trial name
- NCT00209040
- Testing
- Acoustic Startle Testing
- Where
- United States
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Emory University
Moral Injury
Assessing the Implementation and Feasibility of the SMART-MR
The objective of the proposed pilot study is to assess the feasibility and implementation of the SMART-MR program, an integration of stress management, general resilience, and moral resilience skills, with frontline staff who…
- Trial name
- NCT05122910
- Testing
- Stress Management and Resilience Training - Moral Resilience (SMART-MR) program
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Ankylosing Spondylitis
Relationship Between Diet, Oxidative Stress and Inflammation in Ankylosing Spondylitis
Ankylosing Spondylitis (AS) is a chronic inflammatory autoimmune disease. The aim of this study is to reveal the relationship between dietary intake, blood total antioxidant capacity and disease activity in individuals with AS.
- Trial name
- NCT04772976
- Testing
- Observational study, not applicable
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Well Being, Happiness
Laughie Prescription on the Well-being, Happiness, and Posttraumatic Stress Level of Nursing Students Affected by the Earthquake
This study aimed to evaluate the effect of the Laughie Prescription on Well-being, Happiness, and Postraumatic stress levels of nursing students affected by the earthquake in Türkiye.
- Conditions
- Well Being, Happiness, Post Traumatic Stress Disorders
- Trial name
- NCT07157176
- Testing
- Daily 3-Minute Laughter Practice (Laughie Prescription)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
PTSD
Losartan and Memory
This study investigates the effect of a single dose of 50mg losartan vs placebo on BOLD signal during memory encoding.
- Trial name
- NCT05828940
- Testing
- Losartan Potassium
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Burnout, Work Engagement
Buckeye Pause Bundle
Mind-body resilience is particularly important in workplaces where there are frequent exposures to primary or secondary emotional and/or physical trauma. A 2020 report from the U.S.
- Conditions
- Burnout, Work Engagement, Psychological Resilience, Work-Related Stress
- Trial name
- NCT07720297
- Testing
- Augmented Mindfulness-based Intervention, Mindfulness-based intervention
- Where
- 2 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Psychological Trauma, Mental Health
Collaborative Organizational Approach to Selecting and Tailoring Implementation Strategies
The purpose of this study is to partner with the North Carolina Child Treatment Program (NC CTP) and the SAMHSA-funded National Child Traumatic Stress Network (NCTSN) to develop and pilot the Collaborative Organizational Approach…
- Trial name
- COAST-IS (NCT03799432)
- Testing
- COAST-IS, TF-CBT Learning Collaborative
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Post-traumatic Stress Disorder, Post-Traumatic Stress Disorder, Chronic
PTSD Affect Labeling Study
The overall goal of this study is to use fMRI and psychophysiological measures to investigate a novel strategy involving "Affect Labeling" for improving emotion regulation in PTSD that could lead to a new treatment regimen for…
- Trial name
- NCT05924399
- Testing
- Affect Labeling Training
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Psychosis;Schizophrenic, Personality Disorders
The Impact of the COVID-19 (SARS-CoV-2 Disease) on Psychopathology
The outbreak of the SARS-CoV-2 pandemic may be considered a traumatic phenomenon. In a sample of subjects suffering from different psychiatric disorders, psychopathological status and Post-Traumatic Stress Disorder (PTSD)…
- Conditions
- Psychosis;Schizophrenic, Personality Disorders, Mood Disorders, Anxiety Disorders
- Trial name
- NCT04694482
- Testing
- Psychometric scale administration
- Where
- Italy
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Stress Disorders, Post-Traumatic
CPT-fMRI Study for PTSD
Posttraumatic stress disorder (PTSD) is prevalent mental illness (~9% life-time) that results from exposure to trauma. As it is associated with vastly heterogeneous origins, accurate diagnosis and optimal treatment strategies are…
- Trial name
- NCT03229915
- Testing
- cognitive processing therapy
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Post-Traumatic Stress Disorder
Telephone-based Care for OEF/OIF Veterans With PTSD
Objective: OEF/OIF (Operation Enduring Freedom and Operation Iraqi Freedom) veterans are presenting with high rates of PTSD. Translating Initiatives for Depression into Effective Solutions (TIDES) is a model of phone-based care…
- Trial name
- NCT00680524
- Testing
- Phone-based outreach
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Depression, Post Traumatic Stress Disorder
The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry
While effective interventions for depression exist, their success rates are unsatisfactory and their provision is haphazard. The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Depression Hub will improve…
- Conditions
- Depression, Post Traumatic Stress Disorder, Bipolar Disorder, Mood Disorder
- Trial name
- NCT02443636
- Where
- Canada
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Depression - Major Depressive Disorder, Anxiety
Investigating the Protective Impact of LY-2940094 on Stress-induced Depression- and Anxiety-related Phenotypes in Humans
This project will integrate pharmacological and psychophysiological methodology to mechanistically investigate, in humans, the role of N/OFQ in laboratory phenotypes of both disorders.
- Conditions
- Depression - Major Depressive Disorder, Anxiety, Stress
- Trial name
- NCT06786637
- Testing
- Nociceptin Receptor Antagonist (LY-2940094), DS8R Biphasic Constant Current Stimulator
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mclean Hospital
Alzheimer's Disease and Related Dementias
Pilot Testing Dementia-Enhanced Training and Tool for Home Hospice Clinicians
The purpose of this study is to pilot test the feasibility, acceptability, and preliminary efficacy of a clinically useful, inclusive dementia-enhanced training and tool for use by home hospice clinicians to improve care and…
- Trial name
- EDITH-HC (NCT05719077)
- Testing
- EDITH-HC
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Hemophilia Arthropathy
Pain and Joint Status With Psychosocial Factors in Patients With Hemophilia
Background. The recurrence of hemarthrosis in patients with congenital coagulopathies favors the development of a progressive, degenerative intra-articular lesion (hemophilic arthropathy) that mainly affects the knees, ankles and…
- Trial name
- NCT04715100
- Testing
- Observational group
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Stress, Psychological, Stress Disorders, Traumatic
Promoting Resiliency in Veteran Families With Young Children
Family-centered prevention services for civilian dwelling military (CDM) families \& children are rarely available in civilian communities or often framed around mental disorders and family deficits.
- Conditions
- Stress, Psychological, Stress Disorders, Traumatic, Regulation, Self, Behavior, Child
- Trial name
- FOCUS-EC (NCT04598100)
- Testing
- FOCUS-EC
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Opioid-use Disorder, Medication Assisted Treatment
Minds and Mentors Program (MiMP)- R61
The proposed research effort will: The purpose of this study is as follows: 1. Test the feasibility and acceptability of a twelve- week mindfulness based relapse prevention protocol in combination with peer mentoring in…
- Conditions
- Opioid-use Disorder, Medication Assisted Treatment, Substance Use Disorders
- Trial name
- MiMP (NCT04233671)
- Testing
- Mindfulness based relapse prevention and peer mentoring
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Occupational Exposure, Occupational Problems
Relationship Between Health Risk and Occupational Exposure of ED
This study established a sub-cohort of emergency medical workers, for the development of health care and disease prevention solution, by identifying epidemiological characteristics and factors related to occupational exposure.
- Conditions
- Occupational Exposure, Occupational Problems, Occupational Burnout, Medical Emergencies
- Trial name
- NCT05651477
- Testing
- Wearable Device (Smart Watch), Edge-Box
- Where
- South Korea
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
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