Clinical trials: Stroke, Cerebral
Stroke Acute, Emergency Medical Services
Sex diffErences in prehoSpitAl Stroke MEdicine
Background: Stroke is a leading cause for individual, family and societal harm with huge health-economic impact. Immediate and correct prehospital acute stroke pathway initiation is key for treatment success.
- Conditions
- Stroke Acute, Emergency Medical Services, Sex Characteristics, Prehospital Setting
- Trial name
- SESAME (NCT06865950)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Universität des Saarlandes
Acute Ischemic Stroke
Safety and Efficacy Evaluation of the iNstroke 4F Thromboaspiration Catheter in Patients With Acute Ischaemic Stroke Due to Primary Distal Medium Vessel Occlusions (DMVO)
Prospective, Single-arm, Multi-centre Study to Evaluate the Efficacy and Safety of the iNstroke 4F Thromboaspiration Catheter in Patients with Acute Ischaemic Stroke due to Primary Distal Medium Vessel Occlusions.
- Trial name
- 4-NiVO (NCT07357285)
- Testing
- Thromboaspiration catheter
- Where
- 11 sites in Germany, Hungary and 1 more
- Volunteers
- 57 people
- Sponsor
- iVascular S.L.U.
Stroke
Development and Evaluation of iWalk: A Guide to Facilitate Evidence-informed Assessment of Walking After Stroke
Stroke remains a major health concern and the second highest cause of disability worldwide. After experiencing a stroke, many people lose the ability to walk independently.
- Trial name
- NCT04184843
- Testing
- iWalk Toolkit
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Ischemic Stroke
Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN)
This is a double-blind parallel arm randomized trial aimed to assess efficacy and safety of intravenous Tenecteplase compared to intravenous Alteplase in eligible patients who present with symptoms of acute ischemic stroke within…
- Trial name
- TALISMAN (NCT02180204)
- Testing
- Tenecteplase, Alteplase
- Where
- United States
- Sponsor
- Reza Behrouz, DO
Stroke
Study on the Clinical Efficacy of Chinese Medicine Treatment of Sequelae of Apoplexy
This project is one multi-center, a prospective cohort study, based on 1660 cases of ischemic stroke patients with the treatment of 3 months, and 21 months of follow-up observation in order to clarify the advantages and…
- Trial name
- NCT03077984
- Testing
- Chinese medicine treatment
- Volunteers
- 1,660 people
- Sponsor
- Tongsheng Su
Ischemic Stroke, Post-stroke Cognitive Impairment
Safety and Efficacy of ALZT-OP1a as Adjuvant Treatment in Subjects With Post-Ischemic Stroke Cognitive Impairment (PSCI)
This is a Phase II, randomized, double-blinded, placebo-controlled study for subjects with evidence of PSCI.
- Trial name
- NCT03202147
- Testing
- Cromolyn
- Sponsor
- AZTherapies, Inc.
Stroke
Effects of Electromyography-Triggered Constraint-Induced Movement Cycling Therapy on Patients With Chronic Stroke
The study investigates the potential of Electromyography (EMG)-triggered Constraint-Induced Movement Cycling Therapy (CIMCT) versus General Cycling Training (GCT) to enhance balance, strength, and daily activities in chronic…
- Trial name
- NCT06367140
- Testing
- EMG-triggered CIMCT device, general cycling training
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Sahmyook University
Ischemic Stroke
Quality Improvement in Stroke Prevention (QUISP)
Is a secondary prevention intervention, focused on implementation of standardized pre-printed discharge orders for hospitalists, effective at increasing utilization of the following evidence-based treatments 6 months after…
- Trial name
- NCT00328640
- Testing
- Optimal treatment
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of California, San Francisco
Ischemic Stroke, Atrial Fibrillation
Lixiana Acute Stroke Evaluation Registry
Study Design: Lixiana Acute Stroke Evaluation Registry (LASER) is a randomized controlled trial with an associated registry. Patients with previously known or newly diagnosed atrial fibrillation (AF) and acute ischemic stroke…
- Conditions
- Ischemic Stroke, Atrial Fibrillation, Hemorrhagic Transformation Stroke
- Trial name
- LASER (NCT03494530)
- Testing
- Edoxaban 60 MG, Edoxaban 30 mg
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Alberta
Post Stroke, Stroke
Effects of Tai Chi and Dual Task Balance Training in Post Stroke Patients
The aim of the study is to compare the effects of Tai Chi and Dual Task Balance Training on Balance and Fall Risk in Post Stroke Patients
- Trial name
- NCT07854067
- Testing
- Tai Chi, Dual Task Balance Training
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Riphah International University
Stroke, Acute, Endovascular Therapy
Head Position After Endovascular Therapy
The aim of this trial is to investigate whether head elevation position after endovascular treatment can improve the 90-day functional outcome of acute large vessel occlusion in the anterior circulation.
- Trial name
- HeadSOAR (NCT06115707)
- Testing
- The lying flat (0°-10°) head position for 72 hours, The The head elevation (30°-40°) position for 72 hours
- Where
- 67 sites in China
- Volunteers
- 1,368 people
- Sponsor
- Zhengzhou Yuan
Dream Disorder, Thrombotic Infarction
Biological Function of Dreaming in Dreaming and Non-Dreaming Patients With PCA Infarction
This study is a quasi-experimental between-group design. Using a prospective two-arm controlled exploratory study, data will be collected on an initial assessment of the effects of a specific neurological sample after thrombotic…
- Conditions
- Dream Disorder, Thrombotic Infarction, PCA Infarct
- Trial name
- BFD (NCT04749992)
- Testing
- Polysomnographic examination in sleep laboratory (PSG measurement)
- Where
- 2 sites in Germany
- Volunteers
- 142 people
- Sponsor
- International Psychoanalytic University Berlin
Stroke, Transient Ischemic Attack (TIA)
Influence of Stroke on the Composition of Intestinal Microbiota
The aim of the study is to verify the hypothesis that the microbial colonisation of the gut is changed in patients after stroke and that the gut microbiome of severely affected stroke patients differs from that of patients with…
- Trial name
- GUTSTROKE (NCT02008604)
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Charite University, Berlin, Germany
Stroke, RSS
Stimulate the Face to Improve Tactile Acuity on the Hand
The study is a comparative study, to show that the administration of RSS stimulation on the face compared to the administration of strategy Sham stimulation, results in an temporary improvement in the tactile acuity of the hand…
- Conditions
- Stroke, RSS, Face
- Trial name
- FACEHAND (NCT04745247)
- Testing
- RSS
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Hospices Civils de Lyon
Ischemic Stroke, Acute
Methylprednisolone Sodium Succinate With Endovascular ThRombectomy for Large Ischemic STroke
It is uncertain whether intravenous methylprednisolone improves outcomes for acute anterior circulation large vessel occlusion (LVO) patients with a large infarct core.
- Trial name
- PEARL-MERIT (NCT07175649)
- Testing
- Methylprednisolone sodium succinate
- Where
- China
- Volunteers
- 912 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cerebrovascular Accident
The Effect of Dopamine on Motor Skills Training
This study will examine how dopamine, a brain chemical, affects motor training. Taken by mouth, dopamine can enhance motor training, especially during rehabilitation after brain damage.
- Trial name
- NCT00067275
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cognitive Decline, Intracerebral Hemorrhage
Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT) Cognitive Sub-Study
A Sub-Study of an investigator initiated and conducted, multicentre, international, double-blinded, placebo-controlled, parallel-group, randomised controlled trial (TRIDENT) to determine the effect of more intensive long-term…
- Conditions
- Cognitive Decline, Intracerebral Hemorrhage, Dementia, Vascular, Cerebral Small Vessel Diseases
- Trial name
- TRIDENT COG (NCT03785067)
- Testing
- telmisartan 20mg + amlodipine 2.5mg +indapamide 1.25mg
- Where
- 4 sites in Australia, Netherlands
- Volunteers
- 1 people
- Sponsor
- The George Institute
Stroke, Atrial Fibrillation
GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)
In this part of the Registry Program patients with non-valvular atrial fibrillation (AF) at risk for stroke are enrolled to characterize the target population and to collect real world data on important outcome events.
- Trial name
- NCT01671007
- Where
- 522 sites in Austria, Belgium and 20 more
- Volunteers
- 10,471 people
- Sponsor
- Boehringer Ingelheim
Stroke, Muscle Hypertonia
Antagonist Activation Measurement at the Ankle Using High-density and Bipolar Surface EMG in Chronic Hemiparesis
In chronic hemiparesis, abnormal antagonist muscle activation in the paretic lower limb contributes to impair ambulation capacities.
- Conditions
- Stroke, Muscle Hypertonia, Spasticity, Muscle
- Trial name
- CC2017 (NCT06099132)
- Testing
- Electromyographic measurements
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Henri Mondor University Hospital
Stroke
Improved Stroke Outcome at 6 Months
The investigators implemented a structured chain of acute stroke care with early integrated rehabilitation. The mortality at 6 months was lower (12%) compared to 23% in the International Stroke Trial (IST) and 39% (67%) of the…
- Trial name
- NCT00122798
- Testing
- Stroke treatment
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Kantonsspital Baden
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.