Clinical trials: Stroke, Chronic
Chronic Stroke
The Effect of Action Observation Therapy Including Unimanual and Bimanual Activities in Chronic Stroke
Functional impairments in the upper extremities following a stroke significantly restrict individuals' activities of daily living and overall quality of life; in this context, Action Observation Training (AOT) has emerged in…
- Trial name
- NCT07631169
- Testing
- Action Observation Therapy(unimanuel activities), Action Observation Therapy(bimanuel activities), conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Karabuk University
Stroke Sequelae, Chronic Pain
Transcraneal Magnetic Stimulation for Treatment of Non-nociceptive Pain in Chronic Diseases
Background: Chronic non-nociceptive or nociplastic pain and neurological sequelae following stroke are associated with substantial functional impairment and reduced quality of life.
- Conditions
- Stroke Sequelae, Chronic Pain, Fibromyalgia, Long COVID19
- Trial name
- FATMAGPAIN (NCT07888673)
- Testing
- Transcraneal Magnetic Stimulation (rTMS)
- Where
- 2 sites in Spain
- Volunteers
- 47 people
- Sponsor
- Hospital Donostia
Chronic Stroke
Active Balance and Cardio Care Intervention on Physical and Cardiovascular Health in People With Chronic Stroke
Neurological impairment such as stroke is a leading cause of adult disability. Traditional rehabilitative therapies can help regain motor function and ameliorate disability.
- Trial name
- ABCcare (NCT06060470)
- Testing
- Virtual reality based dance group, Active Comparator: Control
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Illinois Chicago
Functional Independence, Balance; Distorted
Relation of Functional ındependence to Balance, Exercise Capacity, and Peripheral Muscle Strength
Stroke is one of the leading causes of death worldwide and is among the most important diseases that cause long-term disability in adults.
- Conditions
- Functional Independence, Balance; Distorted, Exercise Capacity, Peripheral Muscle Strength
- Trial name
- NCT05665673
- Testing
- Physical functions test
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Istinye University
Chronic Stroke
Ankle Robotics for Error Augmentation After Stroke
The goal of this pilot clinical trial is to test whether training with a portable ankle robot improves ankle push-off and walking speed in adults with chronic stroke who have ankle weakness.
- Trial name
- NCT07804342
- Testing
- AMBLE
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Maryland, Baltimore
Stroke, Hemiparesis
Electrical Stimulation for Recovery of Ankle Dorsiflexion in Chronic Stroke Survivors
Ankle dorsiflexor weakness (paresis) is one of the most frequently persisting consequences of stroke. The purpose of this exploratory study is to compare two different treatments -- Contralaterally Controlled Neuromuscular…
- Conditions
- Stroke, Hemiparesis, Lower Extremity Paresis
- Trial name
- NCT01029912
- Testing
- Electrical stimulator
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- MetroHealth Medical Center
Stroke
Home-based Non-invasive Brain Stimulation and Hand Tracking Rehabilitation for People With Chronic Stroke
This is a device feasibility study, which will assess telerehabilitation in people with chronic stroke using a combination of noninvasive brain stimulation and finger tracking training.
- Trial name
- NCT02460809
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Minnesota
Stroke
Aerobic Exercise in Patients With Stroke
The purpose of this study is to compare aerobic training to exergame training in people with chronic mild/moderate stroke. The objectives of this study are two-fold: 1) To evaluate the effects of a home-based aerobic exercise…
- Trial name
- NCT05429255
- Testing
- Aerobic Exercise, Exergame Training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Columbia University
Hemiparesis, Stroke
Effects of Ground Level Gait Training With Body Weight Support (BWS) and Functional Electrical Stimulation (FES)
The aim of this study was to investigate the effects of gait training on ground level, combining BWS and FES in people following chronic stroke.
- Trial name
- NCT01106755
- Testing
- gait training on ground level using BWS, gait training on ground level using BWS associated to FES
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Universidade Federal de Sao Carlos
Muscle Spasticity
Peripheral Modulation of Muscle Stiffness and Spasticity
This is a single-center, double-blind, randomized, placebo-controlled, sequential Phase II trial of human recombinant hyaluronidase injections in individuals with post-stroke upper limb muscle stiffness.
- Trial name
- NCT03306615
- Testing
- Hyaluronidase
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
Stroke
Effect of HIIT on Post-Stroke Fatigue
This study aims to investigate the effect of high-intensity interval training (HIIT) on fatigue severity among individuals with chronic stroke.
- Trial name
- NCT07273058
- Testing
- HIIT, MICT, stretching
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Chronic Stroke, Hemiparesis
Chronic Stroke Rehabilitation With Contralesional Brain-Computer Interface
The purpose of this research study is to show that a computer can analyze brain waves and that those brain waves can be used to control an external device.
- Trial name
- NCT03611855
- Testing
- BCI Rehabilitation, Range of Motion Therapy
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Washington University School of Medicine
Stroke, Chronic Stroke Patients
RESPARK - Brain Q for Chronic Stroke
This trial tests a promising new intervention to promote post-stroke neural reorganization and functional recovery. The Q Therapeutic (BQ 3.0) is a wearable medical system that produces and delivers non-invasive…
- Conditions
- Stroke, Chronic Stroke Patients, Cerebrovascular Accident (CVA)
- Trial name
- NCT07095920
- Testing
- Device: Q Therapeutic System (BQ 3.0) - Active
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
Patients in Minimally Conscious State After a Severe Brain Injury (e.g., Anoxia, Traumatic Brain Injury, Stroke)
tDCS in MCS: Repeated Stimulations
In this study researchers will apply transcranial direct current stimulation (tDCS) for 5 consecutive days in chronic patients in minimally conscious state (MCS).
- Trial name
- tDCS in MCS (NCT02019615)
- Testing
- transcranial direct current stimulation
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University of Liege
Aphasia Following Cerebral Infarction, Aphasia Following Nontraumatic Intracerebral Hemorrhage
TDCS and Aphasia Therapy in the Chronic Phase After Stroke
This study evaluates the neuromodulatory effect of combined tDCS and aphasia therapy in patients in the chronic phase after stroke.
- Trial name
- NCT03305614
- Testing
- tDCS, Aphasia therapy
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- University Hospital, Ghent
Stroke, Ischemic
Effect of Transcutaneous Vagus Nerve Stimulation on Upper Limb Function in Stroke Patients
The goal of this interventional study is to investigate the therapeutic efficacy of non-invasive vagus nerve stimulation on upper limb function in chronic stroke patients .
- Trial name
- NCT06048055
- Testing
- Transcutaneous auricular vagus nerve stimulation, selected physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Chagas Cardiomyopathy, Cardiac Arrhythmia
The Signal-averaged ElectrocArdiogram in Long Term Follow-up of Chronic CHagas Disease - RIO de Janeiro Cohort
The study investigated 100 subjects, both genders, with chronic Chagas disease, confirmed by at least two distinct serological tests, and classified according to Los Andes classification in a long term follow-up aiming at…
- Conditions
- Chagas Cardiomyopathy, Cardiac Arrhythmia, Stroke, Left Ventricular Function Systolic Dysfunction
- Trial name
- SEARCH-Rio (NCT01340963)
- Where
- 4 sites in United States, Brazil
- Volunteers
- 100 people
- Sponsor
- Universidade Gama Filho
CVA (Cerebrovascular Accident)
Wearable Robotic Functional Assistance for Stroke Rehabilitation
This study aims to evaluate the effectiveness of using the myomo e100 wearable robotic rehabilitation system for increasing functional independence and long term rehabilitation of chronic stroke victims with a hemiparetic upper…
- Trial name
- NCT00396708
- Testing
- myomo e100 neurorobotic elbow brace
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Myomo
Stroke, Upper Extremity Paresis
Functional Recovery in Stroke Patients With Task-Specific Robot-Aided Arm Therapy
The goal of this study is to determine whether task-oriented, robot-aided therapy is more effective than conventional physical and occupational therapy at promoting functional recovery of the affected arm in chronic hemiparetic…
- Trial name
- NCT00719433
- Testing
- robot therapy (ARMin), conventional therapy
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- University of Zurich
Chronic Stroke Survivors, Chronic Stroke Patients
Walking and tSCS in Non-ambulatory Stroke Survivors
Rehabilitation interventions commonly used for stroke survivors include task-specific training, balance and strength exercises, and the use of assistive devices to enhance mobility and independence.
- Conditions
- Chronic Stroke Survivors, Chronic Stroke Patients, Stroke
- Trial name
- NCT07226518
- Testing
- Robot-assisted gait training and transcutaneous spinal cord stimulation in chronic non-ambulatory stroke survivors: pilot RCT trial, Robot assisted gait training alone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
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