Clinical trials: Stroke, Chronic
Traumatic Brain Injury, Stroke
Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function
This study aims to recruit patients already implanted with Deep Brain Stimulation (DBS) for movement disorders to complete tasks assessing parameters of motor output, speech, and swallowing functions, both with and without…
- Conditions
- Traumatic Brain Injury, Stroke, Brain Disease, Movement Disorders (Incl Parkinsonism)
- Trial name
- NCT07056348
- Testing
- Deep Brain Stimulation (DBS) of the Motor Thalamus
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jorge Gonzalez-Martinez
Stroke
Whole Body Vibration in Chronic Stroke
This study is a randomized controlled trial aimed to assess the efficacy of a 10-week whole body vibration training program on physical functioning, societal participation and quality of life in individuals with chronic stroke.
- Trial name
- NCT01822704
- Testing
- Low intensity whole body vibration, High intensity whole body vibration, Leg exercises
- Where
- Hong Kong
- Volunteers
- 81 people
- Sponsor
- The Hong Kong Polytechnic University
Brain Damage
Cross-cultural Adaptation to the Spanish Population and Validation of the BESTest and Mini-BESTest
Due to brain damage acquired (BDA), is often difficulty in gait and balance alterations, as problems that patients designated as the most disabling. It is essential to an effective assessment of the balance.
- Trial name
- BESTest (NCT04052087)
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Centro de Referencia Estatal de Atención Al Daño Cerebral
Apathy, Stroke
Transcranial Direct Current Stimulation (tDCS) in Chronic Post-Stroke Apathy
The purpose of this study is to test the efficacy and safety of tDCS (Transcranial Direct Current Stimulation) on apathy in stroke patients.
- Trial name
- TDCS-PSA (NCT02915484)
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stony Brook University
Spina Bifida, Cerebral Palsy
Assessing Transition Practices for Children With Disabilities: Pathways to a Successful Adulthood
Transition to adult care is a purposeful and structured movement of youth with complex disabilities from child centered to adult oriented services. This complex and potentially challenging period requires careful planning.
- Conditions
- Spina Bifida, Cerebral Palsy, Spinal Cord Injury, Spastic Paraplegia
- Trial name
- NCT07706517
- Testing
- Chart review, Semi-structured interview
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Stroke
Robotic Therapy Program for the Arm After Stroke
The aim of this study is to evaluate an outpatient stroke rehabilitation program that uses therapy goal setting and a newly developed, low cost robot for upper limb therapy.
- Trial name
- NCT05321290
- Testing
- Robotic Therapy Program
- Volunteers
- 9 people
- Sponsor
- University Health Network, Toronto
Chronic Stroke Patients
Neuropilates and Otago Exercises on Balance, Posture and Functional Independence in Chronic Stroke
This randomized clinical trial will be conducted at various physical therapy clinics of Faisalabad over a six-month period, enrolling a total of 32 participants selected through non probability convenience sampling technique.
- Trial name
- NCT07293416
- Testing
- neuropilates, otago exercises
- Where
- 3 sites in Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Stroke
Eccentric Contraction-based Resistance Exercise for Chronic Stroke Patients
The purpose of this study is to develop an evidence-based rehabilitation treatment method suitable for recovery and improvement of physical function in chronic stroke patients using an eccentric overload flywheel device.
- Trial name
- NCT04600050
- Testing
- usual care and exercise education, Eccentric exercise
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Bundang Hospital
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Chronic Stroke
Error-enhancement for Arm Rehabilitation Post Stroke
Even in a chronic phase after stroke, most patients have difficulty moving the affected arm, resulting in limitations in simple tasks in daily living, most frequently limiting reaching task.
- Trial name
- NCT05229185
- Testing
- DeXtreme training (error-enhancement)
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cardiovascular Diseases, Coronary Disease
Honolulu Heart Program
To investigate coronary heart disease and stroke among American men of Japanese ancestry who were living on the island of Oahu in 1965. Morbidity and mortality surveillance of the original cohort is continuing.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Cerebrovascular Accident, Heart Diseases
- Trial name
- NCT00005123
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Attention Deficit Disorder With Hyperactivity, Asthma
Study of an Intervention to Improve Problem List Accuracy and Use
The aim of this study is to identify patients with problem list gaps and intervene to correct these gaps by creating clinical decision support interventions that alert providers to likely problem list gaps and offer clinicians…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Asthma, COPD, Breast Cancer
- Trial name
- MAPLE (NCT01105923)
- Testing
- MAPLE
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Brigham and Women's Hospital
Symptomatic Chronic Middle Cerebral Artery Occlusion, Infarction, Middle Cerebral Artery
Extracranial-intracranial Bypass Surgery for Symptomatic Chronic Middle Cerebral Artery Occlusion: the CMOSS-2 Trial
The CMOSS-2 trial is a government-funded, prospective, multicenter, randomized controlled trial. It will recruit symptomatic chronic occlusion of the middle cerebral artery in patients with severe hemodynamic insufficiency.
- Trial name
- NCT05899582
- Testing
- Extracranial-Intracranial Bypass Surgery, Medical treatment alone
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Chronic Stroke
Virtual Physical Activity Seated Exercise - Phase 2
This study will determine the acceptability of delivering seated exercises online and if seated exercises can improve balance, mobility, quality of life, and cardiometabolic health in those living with a stroke related mobility…
- Conditions
- Stroke, Chronic Stroke, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- V-PASE (NCT05724823)
- Testing
- Virtual Physical Activity Seated Exercises (V-PASE)
- Where
- 5 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Chronic Stroke Survivors
PoNS® Therapy for Gait and Balance Deficits in Chronic Stroke Survivors: A Single-Arm Study
Primary Objective: To further evaluate the aspects of safety related to PoNS therapy in chronic stroke survivors. Secondary Objectives: To further evaluate the efficacy of PoNS on improving dynamic gait and balance, establishing…
- Trial name
- NCT06336720
- Testing
- Portable Neuromodulation Stimulator (PoNS)
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Helius Medical Inc
Motor Recovery
BreEStim for Motor Recovery in Chronic Stroke With Severe Impairment (Pilot)
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with…
- Trial name
- NCT04750564
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Coronary Artery Disease, Atrial Fibrillation (AF)
Medical Large Language Model-Assisted Diagnosis and Treatment in Primary Care Chronic Disease Management
This study aims to explore the feasibility of using medical large language models to assist in chronic disease management. By setting up experimental and control group interventions and having experts blindly evaluate anonymized…
- Conditions
- Coronary Artery Disease, Atrial Fibrillation (AF), Heart Failure, Stroke
- Trial name
- NCT07740044
- Testing
- Medical large language model
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Jiangsu Taizhou People's Hospital
Cerebrovascular Disorders, Cerebral Stroke
Using Repetitive Transcranial Magnetic Stimulation (rTMS) in the Rehabilitation of Chronic Spatial Neglect After Stroke
Visuospatial neglect is a common neurological symptom which appears following strokes on regions of the right hemisphere of the brain.
- Conditions
- Cerebrovascular Disorders, Cerebral Stroke, VISIO-spatial Neglect, VISUO-spatial Extinction
- Trial name
- NEGLECT (NCT01000103)
- Testing
- Real rTMS
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Functional Independence, Balance; Distorted
Relation of Functional ındependence to Balance, Exercise Capacity, and Peripheral Muscle Strength
Stroke is one of the leading causes of death worldwide and is among the most important diseases that cause long-term disability in adults.
- Conditions
- Functional Independence, Balance; Distorted, Exercise Capacity, Peripheral Muscle Strength
- Trial name
- NCT05665673
- Testing
- Physical functions test
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Istinye University
End-Stage Renal Disease, Stroke
Assessing Cognitive fUnction and MEasuring the Cerebral circulatioN on HaemoDialysis
Stroke disease and cognitive impairment are common in patients established on haemodialysis (HD) for end-stage renal disease (ESRD). Further, initiation of HD appears to transiently increase the risk of stroke.
- Conditions
- End-Stage Renal Disease, Stroke, Cognition Disorders
- Trial name
- ACUMEN-HD (NCT02393222)
- Testing
- Observing effect of routine HD
- Volunteers
- 97 people
- Sponsor
- NHS Greater Glasgow and Clyde
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