Clinical trials: Stroke, Chronic
Chronic Stroke
Brain Stimulation and Robotics in Chronic Stroke Motor Recovery
Motor skill training and transcranial direct current stimulation (tDCS) have separately been shown to alter cortical excitability and enhance motor function in humans.
- Trial name
- NCT03562663
- Testing
- Transcranial direct current stimulation, Upper extremity robotics
- Volunteers
- 82 people
- Sponsor
- Burke Medical Research Institute
Stroke, Stroke Rehabilitation
COMPERATIVE EFFECTS of CONSTRAINT- INDUCED MOVEMENT THERAPY and MIRROR THERAPY on FUNCTIONAL AMBULATION and QUALITY of LIFE in CHRONIC STROKE PATIENTS
Stroke is a global health issue as this happens when the blood flow to the brain is disrupted or reduced, depriving the brain tissue of sugar and oxygen.
- Conditions
- Stroke, Stroke Rehabilitation, Mirror Therapy, Quality of Life (QOL)
- Trial name
- NCT06807814
- Testing
- Constraint-Induced Movement Therapy (CIMT)), Mirror Therapy
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- University of Lahore
Stroke
Reliability and Validity of the Vicorder Device When Measuring Pulse Wave Velocity Within Chronic Stroke Patients
Stroke is a major global health problem and main cause of disability worldwide. Blood pressure control is important for good health in stroke patients.
- Trial name
- NCT04342143
- Testing
- Blood pressure and ultrasound assessment
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Winchester
Stroke
Effect of Lower Limb Proprioceptive Neuromuscular Facilitation Combined With Core Stability Training Versus Proprioceptive Neuromuscular Facilitation Alone on Balance and Functional Mobility in Chronic Stroke Survivors
This randomized controlled trial compares lower limb proprioceptive neuromuscular facilitation (PNF) combined with core stability training versus lower limb PNF alone in chronic stroke survivors.
- Trial name
- NCT07887360
- Testing
- Lower Limb PNF Combined with Core Stability Training, Lower Limb PNF alone
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Ibadat International University, Islamabad
Cerebral Palsy, Stroke
Feasibility of the Portable YouGrabber System
The aim of the study is to determine the feasibility of the portable version of the YouGrabber® system in children with central motor disorders.
- Conditions
- Cerebral Palsy, Stroke, Traumatic Brain Injury, Meningomyelocele
- Trial name
- YouGrabber (NCT02368223)
- Testing
- YouGrabber
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University Children's Hospital, Zurich
Pulmonary Disease (COPD), Chronic Obstructive, Lung Resection Surgery
Effect of Individualized Positive End-expiratory Pressure (PEEP) in Patients Who Have an Intrinsic PEEP During One-lung Ventilation
This study investigates the effects of three extrinsic PEEP settings-5 cmH2O, 0 cmH2O, and an individualized PEEP (70% of the measured intrinsic PEEP)-on intrinsic PEEP and hemodynamic stability in patients with intrinsic PEEP…
- Trial name
- NCT07638176
- Testing
- PEEP0, PEEP5, PEEPi
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Samsung Medical Center
Stroke
Exercise Training and Walking Ability After Chronic Stroke
This study will investigate the efficacy of aerobic exercise and progressive resistance training (PRT), singularly and combined, on changes in walking endurance for mildly-to-moderately affected chronic stroke patients.
- Trial name
- NCT00107068
- Testing
- [A] Aerobic isokinetic cycling exercise, [B] Progressive Resistance Training, [A] + [B]
- Where
- Australia
- Volunteers
- 48 people
- Sponsor
- University of Sydney
Stroke, Spasticity
Effectiveness of Dry Needling (DNHS Technique) in Patients With Chronic Stroke
Study hypothesis: The DNHS technique, performed via one session of deep dry needling of myofascial trigger points applied to the biceps brachii, brachialis, flexor digitorum superficialis, flexor digitorum profundus, triceps…
- Trial name
- NCT03546517
- Testing
- Dry Needling
- Where
- Spain
- Volunteers
- 23 people
- Sponsor
- Universidad San Jorge
Stroke
Evaluation of Sensorimotor Ankle Impairments in Chronic Stroke
The purpose of this study is to capture sensorimotor ankle function in a chronic stroke population through validation of novel, experimental metrics and their comparison with established, clinical measures of function.
- Trial name
- NCT06410989
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Virtual Environment Rehabilitation for Chronic Stroke
More than half of individuals post-stroke have residual movement disabilities, including reduced mobility, balance, and increased risk of falling.
- Trial name
- VEHAB (NCT01414686)
- Testing
- Commercially-Available Interactive Video Games
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of South Carolina
Stroke, Coronary Arterial Disease (CAD)
Algae Effects in Markers of Cardiovascular Risk and Gut Microbiome
The Western diet, rich in fat and sugar, contributes to cardiovascular risk and alters the body metabolism, specifically through the modulation of the microbiome.
- Conditions
- Stroke, Coronary Arterial Disease (CAD), Myocardial Infarction (MI), Diabetes Mellitus
- Trial name
- CALGUT (NCT07173062)
- Testing
- Spirulina Arthrospira platensis (microalgae), Gelidium corneum
- Where
- Portugal
- Volunteers
- 150 people
- Sponsor
- Universidade do Porto
Chronic Stroke
Repetitive Transcranial Magnetic Stimulation Associated With Physical Therapy to Reduce Upper Limb Spasticity in Post Stroke Patients
In this study, it is being investigated if the association between high frequency repetitive transcranial magnetic stimulation associated with motor physical therapy reduces spasticity, increases upper limb motor function, and…
- Trial name
- NCT03481179
- Testing
- TMS, Physical therapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Acute Ischemic Stroke, Intracranial Arterial Stenosis
Post-Market Active Surveillance and Health Economic Evaluation of Cerebrovascular Diagnostic and Therapeutic Devices
The research focuses on "post-market active surveillance and health economic evaluation of non-pharmacological therapies and innovative cerebrovascular diagnostic and therapeutic devices".
- Conditions
- Acute Ischemic Stroke, Intracranial Arterial Stenosis, Extracranial Arterial Stenosis, Intracranial Aneurysms
- Trial name
- NCT07828379
- Testing
- Endovascular Treatment for Acute Ischemic Stroke
- Volunteers
- 2,000 people
- Sponsor
- Changhai Hospital
Chronic Stroke
Five-year Changes in Patients With Chronic Stroke
Objective of the study: To determine changes in physical and cognitive function in patients with chronic stroke over 5 years To determine whether there are differences in physical and cognitive function in chronic stroke patients…
- Trial name
- NCT06191406
- Testing
- 6 minute walk test
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Khon Kaen University
Stroke, Intervention
The Effectiveness and Mechanism of Character Strengths-based STEP Programme on Rehabilitation of Stroke Patients
There is an urgent need for educational and psychological adjustment to stimulate the post-stroke patients' motivation to actively carry out rehabilitation.
- Conditions
- Stroke, Intervention, Rehabilitation, Depression
- Trial name
- STEP (NCT05738499)
- Testing
- Character strengths-based structured treatment and education programme (CSSTEP), Structured treatment and education programme (STEP)
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Peking University
Chronic Stroke, Spasticity as Sequela of Stroke
Effects of EMG-driven Robot-assisted Therapy for the Distal Upper Limb Motor Function in the Chronic Stroke Patients With Botox Injections
Over fifty percent of stroke patients experience chronic arm hand performance problems, compromising independence in daily life activities and quality of life.
- Conditions
- Chronic Stroke, Spasticity as Sequela of Stroke, Robotic Rehabilitation
- Trial name
- NCT04502264
- Testing
- Hand of Hope, Botulinum toxin type A injection
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Cheng-Hsin General Hospital
Chronic Stroke, Subacute Stroke
Effect of Lower Limb Constraint Induced Movement Therapy Using a Torque-Assisted Exoskeletal Wearable Device
The aim of this study was to investigate the effects of lower limb constraint induced motor therapy using the robotic rehabilitation device on ambulatory function in chronic stroke patients.
- Trial name
- CIMT (NCT06830707)
- Testing
- experimental group
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Samsung Medical Center
Stroke
Core Stability, Symmetrical Weight-bearing Stroke
To evaluate the effect of core stability exercise on symmetrical weight bearing in chronic stroke patients?
- Trial name
- NCT06267079
- Testing
- core stability exercise
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Inflammatory Demyelinating Polyradiculoneuropathy, Stroke
Processing Integration in Neurological Patients Using fMRI
The main objective of the study is to explore and map brain areas involved in processing and perception in patients suffering from neurological pathologies and condition.
- Conditions
- Acute Inflammatory Demyelinating Polyradiculoneuropathy, Stroke, Anosognosia, Central and Peripheral Neurodegenerative Pathologies
- Trial name
- NCT02722070
- Testing
- 3 Tesla Siemens Skyra MRI scanner
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Stroke, Chronic Stroke Patient
Effects of I-STROKEFIT+ on Physical Fitness Among Community-Dwelling Stroke Survivors: A Pilot RCT
This pilot randomized controlled study will evaluate whether a 12-week integrated home-based physical fitness and self-management programme (i-StrokeFit+) can improve physical fitness and physical activity among…
- Conditions
- Stroke, Chronic Stroke Patient, Stroke (6 Months or More After Onset), Community Dwelling
- Trial name
- NCT07824570
- Testing
- Physical fitness and Self-Management, Patient Education
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- Universiti Teknologi Mara
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