Clinical trials: Stroke, Chronic
Stroke, Cerebrovascular Accident
Clinic-Based AMES Treatment of Stroke
This study investigates whether assisted movement with biofeedback and muscle vibration applied to the lower limb reduces impairment and improves gait.
- Trial name
- NCT00847704
- Testing
- Assisted movement and enhanced sensation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Oregon Health and Science University
Stroke
Effect of Mirror Therapy Versus Bilateral Arm Training for Rehabilitation After Chronic Stroke
The study purpose is to compare the efficacy of mirror therapy and bilateral arm training on movement strategies of the affected upper extremity and functional outcome in chronic stroke patients.
- Trial name
- NCT02548234
- Testing
- Mirror therapy, Bilateral arm training
- Where
- Taiwan
- Volunteers
- 29 people
- Sponsor
- China Medical University Hospital
Stroke
Fall-recovery Training for Those With Chronic Stroke and Low Falls Self-efficacy
Chronic stroke is the leading cause of long-term disability in the United States. Post-stroke health is negatively impacted by two interrelated factors-a substantial risk of falls and limited walking activity.
- Trial name
- NCT04112173
- Testing
- perturbation-based fall-recovery training
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Delaware
Stroke, Ischemic, Ambulation Disorder, Neurologic
Blood Flow Restricted High-Intensity Treadmill Training on Independently Ambulating Chronic Ischemic CVA Survivors
Individuals surviving Chronic Ischemic Stroke have lingering walking deficits long after their infarct. The main goal of this study is to compare two high intensity treadmill walking programs to see which improves walking more.
- Conditions
- Stroke, Ischemic, Ambulation Disorder, Neurologic, Chronic Stroke
- Trial name
- NCT06214494
- Testing
- Blood Flow Restricted High Intensity Treadmill Training, HITT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- MedStar National Rehabilitation Network
Stroke
Vibration Training for Patients With Chronic Stroke
A 4-week program of vibration training in a seated position combined with conventional rehabilitation led to significant improvements in unaffected side lower limb muscle strength, functional recovery, quality of life, and…
- Trial name
- NCT07554794
- Testing
- vibration training
- Where
- Taiwan
- Volunteers
- 39 people
- Sponsor
- CHIA-HUEI LIN, PhD
Chronic Stroke
Spinal Cord Stimulation Combined With Motor Imagery Brain-Computer Interface for Chronic Post-Stroke Upper Limb Motor Dysfunction
This clinical study aims to evaluate the efficacy and safety of spinal cord stimulation combined with non-invasive motor imagery brain-computer interface rehabilitation training in patients with upper limb motor dysfunction after…
- Trial name
- NCT07686822
- Testing
- Spinal Cord Stimulation, Motor Imagery Brain-Computer Interface Rehabilitation Training
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhejiang Provincial People's Hospital
Stroke
Strength Training for Chronic Stroke Patients
The study aims to investigate the effects of strength training on maximal strength, walking ability and neural function in chronic stroke patients.
- Trial name
- NCT01003353
- Testing
- Maximal strength training
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Norwegian University of Science and Technology
Stroke, Brain Diseases
Predictors of Response in Chronic Stroke
This study will validate a predictive model that uses demographics, functional status, neurophysiology, neuroanatomy, and other potential biomarkers to predict the likelihood of a clinically significant change in impairment at…
- Conditions
- Stroke, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases
- Trial name
- SRT5 (NCT04283253)
- Testing
- Robot + TTT exercise
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- VA Pittsburgh Healthcare System
Stroke
HABIT-ILE in Adults With Chronic Stroke (HABIT-ILE Stroke)
Using a randomized controlled trial design, the possible changes induced by the intensive treatment program "Hand-arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE)" will be studied in functional, everyday…
- Trial name
- NCT04664673
- Testing
- Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE), Regular care
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Université Catholique de Louvain
Stroke
Robotic and Conventional Hand Therapy After Stroke
Weakness is a major cause of disability in stroke survivors. Rehabilitation techniques are often not effective in restoring full function of the upper limb.
- Trial name
- NCT03020576
- Testing
- Amadeo Hand Robot Device, Conventional Therapy
- Where
- 2 sites in United States, Austria
- Volunteers
- 31 people
- Sponsor
- Columbia University
Stroke, Chronic Stroke
Optimizing Training in Severe Post-Stroke Walking Impairment
Difficulty walking is common after a stroke. Although physical rehabilitation helps a little with the improvement of walking ability, recovery is usually incomplete.
- Conditions
- Stroke, Chronic Stroke, Walking, Difficulty, Gait, Hemiplegic
- Trial name
- BLT2b (NCT04721860)
- Testing
- Backward Locomotion Treadmill Training (BLTT), Forward Locomotion Treadmill Training (FLTT)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Cincinnati
Left-Hemisphere Stroke
Brain Markers Predicting Reading Recovery After Stroke
For millions of stroke survivors acquired reading deficits represent a significant handicap preventing them from returning to work or continuing their education.
- Trial name
- NCT03845686
- Testing
- Perfusion functional Magnetic Resonance Imaging (perfusion fMRI)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Kessler Foundation
Chronic Stroke
PNF With and Without EMS on Spasticity, Gait and Lower Limb Function in Chronic Stroke Patients
The main purpose of conducting this study is to decrease the tone through PNF techniques and EMS application. By decreasing the tone, spasticity may be reduced in stroke patients and may inturn lead to better approaches to treat…
- Trial name
- NCT05962060
- Testing
- Proprioceptive neuromuscular facilition, Electrical muscle stimulator
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Ischemic Stroke, Obstructive Sleep Apnea
Obstructive Sleep Apnea Treatment From Acute to Chronic Phase of Stroke
The study aims to evaluate whether early treatment of obstructive sleep apnea with continuous positive airway pressure in ischemic stroke patients has a favorable effect on functional recovery.
- Trial name
- ATACS (NCT07044830)
- Testing
- CPAP
- Where
- Brazil
- Volunteers
- 425 people
- Sponsor
- Hospital das Clínicas de Ribeirão Preto
Spasticity, Cerebrovascular Accident
Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity
Phase 2/3, randomized, double-blind, placebo-controlled, single-treatment, multicenter trial assessing the efficacy and safety of MYOBLOC for the treatment of upper limb spasticity in adults followed by an open-label extension…
- Conditions
- Spasticity, Cerebrovascular Accident, Multiple Sclerosis, Traumatic Brain Injury
- Trial name
- NCT04815967
- Testing
- Phase 2; Low Dose MYOBLOC (10,000 Units), Phase 2; High Dose MYOBLOC (20,000 Units), Phase 3; MYOBLOC
- Where
- 9 sites in United States, Hungary and 1 more
- Volunteers
- 32 people
- Sponsor
- Solstice Neurosciences, LLC, a subsidiary of MDD US Operations, LLC
Stroke, Hemiplegic Shoulder Pain
Focal Vibration Therapy in Post-stroke Shoulder Pain
Hemiplegic Shoulder Pain (HSP) is a common and disabling complication after stroke, negatively affecting upper limb function, participation in rehabilitation, and quality of life.
- Conditions
- Stroke, Hemiplegic Shoulder Pain, Chronic Stroke Survivors
- Trial name
- VIBRA-HSP (NCT07513753)
- Testing
- Multimodal Focal Vibration Therapy (FVT), Standard Rehabilitation Program
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Foggia
Gait Impairment, Cerebral Palsy (CP)
Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting
The primary objective of the study is to validate the safety and clinical performance of the ABLE Kids device in pediatric patients with neurological gait disorders or muscular weakness during a 10-session gait training program…
- Conditions
- Gait Impairment, Cerebral Palsy (CP), Neuromuscular Diseases (NMD), Spinal Cord Injuries (SCI)
- Trial name
- NCT07745712
- Testing
- ABLE Kids
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- ABLE Human Motion S.L.
Stroke, Hemiparesis
Electrical Stimulation for Recovery of Hand Function in Chronic Stroke Survivors
Impaired hand function is one of the most frequently persisting consequences of stroke. The purpose of this study is to compare two different treatments -- Contralataterally Controlled Functional Electrical Stimulation (CCFES)…
- Conditions
- Stroke, Hemiparesis, Hemiplegia
- Trial name
- NCT00891319
- Testing
- Electrical stimulator
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- MetroHealth Medical Center
Stroke
Assessing Upper Extremity Function in Chronic Stroke Survivors Through Acute Intermittent Hypoxia
Here we aim to observe effects of acute intermittent hypoxia in persons who have experienced a single stroke. We have previously shown this technique to be safe and effective at increasing strength in persons with disabilities…
- Trial name
- NCT07113457
- Testing
- Acute Intermittent Hypoxia (AIH)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Rehabilitation
tDCS Response Prediction Using EEG in Stroke
Patients with chronic stroke (>6 months after stroke) having unilateral upper limb hemiparesis will be recruited. Patients will maintain their usual inpatient rehabilitation including occupational therapy.
- Conditions
- Stroke, Rehabilitation, Transcranial Direct Current Stimulation, Motor Recovery
- Trial name
- NCT04830631
- Testing
- Cathodal transcranial direct current stimulation (tDCS) over the contralesional motor cortex
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
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