Clinical trials: Stroke, Chronic
Diabetic Retinopathy, Macular Degeneration
Advancing Understanding of Transportation Options
This Stage II randomized, controlled, longitudinal trial seeks to assess the acceptability, feasibility, and effects of a driving decision aid use among geriatric patients and providers.
- Conditions
- Diabetic Retinopathy, Macular Degeneration, Glaucoma, Retinitis Pigmentosa
- Trial name
- AUTO (NCT04141891)
- Testing
- Driving Decision Aid, Older Drivers Website
- Where
- 3 sites in United States
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Aphasia, Stroke
Brain Correlates of Multimodal Rehabilitation in Chronic Post-stroke Aphasia
Post-stroke aphasia (PSA), the partial or total loss of the ability to produce and/or understand language associated with stroke, is a highly prevalent and disabling disorder that negatively impacts the personal, social and…
- Trial name
- NCT04134416
- Testing
- Donepezil, Intensive-Language Action Therapy, Transcranial direct current stimulation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Malaga
Stroke, Chronic Stroke
Analysis Acceleration/Deceleration Distance Gait Speed Tests in Stroke Survivors
Introduction: Gait speed is currently used to predict the future functional status of the patient or to evaluate the improvements produced by different neurorehabilitation treatments.
- Trial name
- Walk-test (NCT05679011)
- Testing
- 4 and 6 meters walking test
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universitat Internacional de Catalunya
Stroke
Vestibular Training on Community Ambulation and Fall Risk in Stroke
Nearly half of individuals with stroke experience limitations in community ambulation, and 35.7% of community-dwelling stroke survivors experienced falls while walking, indicating that falls are common during routine daily…
- Trial name
- NCT07494500
- Testing
- Vestibular training, Conventional physical therapy
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Yang Ming Chiao Tung University
Chronic Stroke
Game-Based Home Exercise Programs in Chronic Stroke: A Feasibility Study
Study will look at the effect of a game-based, task-oriented home exercise program on adherence in persons with chronic (> 6 months post) stroke as compared to a standard home exercise program.
- Trial name
- NCT03531567
- Testing
- Virtual Reality Mystic Isle Game, Standard Home Exercise Program
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Missouri-Columbia
Chronic Hemiparetic Stroke
Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke
Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-related care annually at a cost…
- Trial name
- NCT06400186
- Testing
- High intensity gait training in varying external environments, Treadmill walking in varying external environments
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Disease, Arterial Stiffness
Natural History Study of CADASIL
Background: CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy) is a genetic disorder. It causes narrowing of the small blood vessels and can lead to strokes and dementia.
- Conditions
- Cardiovascular Disease, Arterial Stiffness, Germline Mutation in the NOTCH 3 Gene, Pathogenesis of CADASIL
- Trial name
- NCT05072483
- Testing
- MRI
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Stroke, Hemiplegia
Implementing Technology Enhanced Real Time Action Observation Therapy in Persons With Chronic Stroke
This is a feasibility study to alter the Microsoft Kinect software to be used as a rehabilitation tool. The prototype used is still in the early developing stage.
- Conditions
- Chronic Stroke, Hemiplegia, Hemiparesis, Paralysis
- Trial name
- TERTAOT (NCT03780296)
- Testing
- Real-time action observation with augmented Kinect
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Michigan
Chronic Stroke
Dyad Learning in Wrist-robotic Environment After Stroke
"Robot-assisted rehabilitation is used to mitigate the devastating effects of stroke and to recover the ability to perform complex motor tasks in survivors.
- Trial name
- NCT06154031
- Testing
- Dyad learning
- Sponsor
- University of Minnesota
Stroke
The Immediate Effects of Intermittent Theta Burst Stimulation on Intracortical Excitability of the Primary Motor Cortex in Patients With Chronic Stroke
This study is to investigate the immediate effects of intermittent theta burst stimulation (iTBS) on intracortical excitatory and inhibitory circuits, neural connectivity, and network properties in patients with chronic stroke…
- Trial name
- NCT05509686
- Testing
- Intermittent theta burst stimulation (iTBS)
- Where
- Hong Kong
- Volunteers
- 21 people
- Sponsor
- The Hong Kong Polytechnic University
Cyanotic Congenital Heart Disease
Preventing Brain Injury in Infants With Congenital Heart Disease
Newborn babies with congenital heart disease often require surgery in the first month of life. The risks of brain damage from congenital heart disease and from the various corrective surgeries are high because of poor levels of…
- Trial name
- NCT01426542
- Testing
- Topiramate, No medication, but routine heart surgery
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, Davis
Ischemic Stroke, Upper Extremity Problem
VNS-REHAB At-Home - Post-Market Study for Using the Vivistim System® at Home
This is a single-arm post-market study of up to 150 participants, using up to 50 mobile therapists to conduct up to 36-hours at-home therapy.
- Trial name
- AT-HOME (NCT05691023)
- Testing
- Vivistim System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- MicroTransponder Inc.
Stroke
Effects of Home-based Neurostimulation Associated With Motor Training in Chronic Stroke Patients
Objective: To investigate effects of home-based somatosensory stimulation associated with motor training on improvement in performance of the paretic upper extremity in patients in the chronic phase after stroke.
- Trial name
- NCT01034150
- Testing
- Relief band (Somatosensory stimulation)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo General Hospital
Cerebral Palsy, Developmental Delay
SmarToyGym: Smart Detection of Atypical Toy-oriented Actions in At-risk Infants
The study aims to develop a SmarToyGym where sensitized, wireless toys are strategically hung and placed within reach of infants to elicit toy-oriented body and arm/hand movements.
- Conditions
- Cerebral Palsy, Developmental Delay, Stroke, Fine Motor Delay
- Trial name
- NCT02813889
- Testing
- SmarToyGym
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke
Eccentric Contraction-based Resistance Exercise for Chronic Stroke Patients
The purpose of this study is to develop an evidence-based rehabilitation treatment method suitable for recovery and improvement of physical function in chronic stroke patients using an eccentric overload flywheel device.
- Trial name
- NCT04600050
- Testing
- usual care and exercise education, Eccentric exercise
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Bundang Hospital
Stroke, Cerebrovascular Disorders
Home-based Cognitive Strategy Training for Daily Living in Adults With Chronic Stroke
This pilot experimental study aims to describe the feasibility of a cognitive strategy training protocol : PRPP-I, in activities of daily life across home-based setting for adults with chronic stroke for improvement of…
- Trial name
- PRPP-HOME (NCT07084025)
- Testing
- Perceive, Recall, Plan and Perform-Intervention protocol (PRPP-I)
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Stroke, Cerebrovascular Accident
Bilateral Movement Training for People With Stroke
The investigators hypothesized that bilateral handgrip force training would result in significant improvements in paretic hand, arm movements and daily functional performances.
- Conditions
- Stroke, Cerebrovascular Accident, Cardiovascular Disease, Brain Injury
- Trial name
- NCT02247674
- Testing
- Bilateral movement training
- Where
- Taiwan
- Volunteers
- 33 people
- Sponsor
- Chueh-Ho Lin
Healthy, Cerebrovascular Accident
Improvement of Use Dependent Plasticity in Chronic Stroke Patients
This study will examine the role of an amphetamine in improving the effect that electrical nerve stimulation has over brain flexibility associated with motor training in patients who experienced a stroke more than 1 year before.
- Trial name
- NCT00072735
- Testing
- Electrocardiogram
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Chronic Stroke
Dyadic Interventions to Boost Quality of Life Among Stroke Survivors and Care Partners in Pakistan.
This study (RCTs) will be conducted on stroke survivors and their care partners after discharge from the hospital. The study will aim to evaluate the impact of augmented dyadic intervention on the quality of life of stroke…
- Trial name
- NCT06827093
- Testing
- Skill Building Dyadic Intervention
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Zhengzhou University
COPD, Congestive Heart Failure
Use of Non Invasive Hemodynamic Cardiovascular Monitoring to Evaluate Emergency Department Patients
This study is an observational prospective pilot trial that utilizes finger cuff non invasive hemodynamic monitoring (NexfinHD Monitor) to assess 4 different groups (CHF/COPD, Trauma, Sepsis, Stroke) of patients on arrival to the…
- Conditions
- COPD, Congestive Heart Failure, Trauma, Sepsis
- Trial name
- NCT00851214
- Testing
- NexfinHD Monitor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Henry Ford Health System
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