Clinical trials: Stroke, Chronic
Stroke, Acute Stroke
The Effects of Gait Rehabilitation After Stroke by Treadmill-based Robotics Versus Traditional Gait Training
This multicenter non-randomized controlled trial aims to investigate the effectiveness (an increase of the walking speed in the 10 Meter Walk Test - 10MWT) of the robotic treatment with exoskeleton or end-effector system compared…
- Conditions
- Stroke, Acute Stroke, Chronic Stroke
- Trial name
- TREAD_STROKE (NCT03688165)
- Testing
- Treadmill-based Robotic Gait Training, Traditional Over-ground Gait Training
- Where
- 4 sites in Italy
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Chronic Ischemic Stroke
Vagal Nerve Stimulation in Enhanced Stroke Recovery: The VALOR Registry
Vagal Nerve Stimulation is a novel proven therapy for patients with chronic ischemic stroke. The primary objective of this registry is to assess the safety of vagal nerve stimulation for stroke recovery through monitoring the…
- Trial name
- VALOR (NCT05694663)
- Testing
- Vivistim
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Stroke, Parkinson Disease
Feasibility of Two New Software Modules for the Rehabilitation of Patients With Neuromuscular Upper Limb Impairments
Introduction: In the recent past, medical training systems using virtual reality (VR) have been introduced to neurorehabilitation to train motor function deficits in patients.
- Conditions
- Stroke, Parkinson Disease, Traumatic Brain Injury, Guillain-Barre Syndrome
- Trial name
- NCT03268304
- Testing
- VR-based training including AO and MI
- Sponsor
- Reha Rheinfelden
Chronic Stroke
Effects of Action Observation Therapy on Fine Motor Skills of Upper Limb Functions in Chronic Stroke Patients.
This study will be conducted to evaluate the outcomes of action observation therapy on fine motor skills of affected upper limb among patients with chronic stroke.
- Trial name
- NCT04574687
- Testing
- Neurodevelopmental Techniques, Action observation Therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Stroke, Ischemic, Stroke Hemorrhagic
Prediction Model for Chronic Intracranial Arterial Occlusion With Radiomic Features
Chronic intracranial arterial occlusion is associated with a "bidirectional stroke risk," with a significantly increased risk of both ischemic stroke and cerebral hemorrhage.
- Trial name
- NCT06066593
- Where
- 2 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Hospital
Chronic Stroke
Can Patients With Chronic Stroke Regain Living Independence by Daily Energizing With Biophoton Generators
Study objective The purpose of this clinical research is to verify if the patient with chronic stroke can regain the ability of living independently after daily using Testa BioHealing® Biophoton Generators to increase the energy…
- Trial name
- NCT06049849
- Testing
- Biophoton Energizing Brain and Whole Body
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- First Institute of All Medicines
Stroke
Clinical Effects of Peroneal Nerve Functional Electrical Stimulation (WalkAide[R]) for Chronic Stroke Patients
RATIONALE: The previous study resulted that the gait training using Functional Electrical Stimulation (FES) improved the ankle joint function and the walking ability for the chronic stroke patients with foot drop.
- Trial name
- PLEASURE (NCT02897752)
- Testing
- gait training with WA, usual gait training
- Where
- 24 sites in Japan
- Volunteers
- 120 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Stroke, Peripheral Neuropathy
Arm Motor Control on Bi and Uni ADLs
This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs.
- Conditions
- Stroke, Peripheral Neuropathy, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- BiAs (NCT02778529)
- Testing
- Bilateral assessment robots (BiAS)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke, Cerebrovascular Accident
AMES Treatment of the Proximal Arm in Chronic Stroke
Subjects will receive 30 treatments with AMES, to the proximal arm which has been affected by a chronic stroke.
- Trial name
- AMES (NCT01934439)
- Testing
- 30 PAAD treatments
- Where
- United States
- Sponsor
- Oregon Health and Science University
Stroke
Investigation of Factors Causing Knee Hyperextension During Walking in Chronic Stroke Patients
In this study, it is aimed to examine the factors that cause knee hyperextension in chronic stroke patients. Although the presence of weakness or spasticity in the quadriceps muscle, weakness or spasticity in the plantar flexors…
- Trial name
- NCT05513781
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Hacettepe University
Stroke
Thoracolumbar Fascia Thickness in Chronic Stroke Patients
The main objective of this study was to examine the thoracolumbar fascia thickness in chronic stroke patients using objective methods and to reveal the relationship of this flexibility with balance, trunk control, trunk…
- Trial name
- NCT07107295
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara University
Stroke, Multiple Sclerosis
Design and Validation of Innovative Strategies Based on Dual-Task Approach
People affected by Stroke, Multiple Sclerosis (MS), and Parkinson's disease (PD) share severe and complex disabilities. Widespread neuro-inflammatory processes represent an important pathogenetic component in all three…
- Conditions
- Stroke, Multiple Sclerosis, Parkinson Disease, Dual Task Exercises
- Trial name
- START (NCT07254377)
- Testing
- Dual Task exercise, Physical therapy
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Idiopathic Toe Walking, Cerebral Palsy
The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in Children
Tight ankle muscles can produce ankle equinus (limited ability to pull the foot upward) and occur often in children, significantly impacting their ability to walk.
- Conditions
- Idiopathic Toe Walking, Cerebral Palsy, Hereditary Spastic Paraparesis, Traumatic Brain Injury
- Trial name
- Plantaris Sx (NCT07090057)
- Testing
- Tendoachilles (TA) lengthening or gastrocnemius (GN) recession, then Plantaris tenotomy, Plantaris tenotomy, then Tendoachilles (TA) lengthening or gastrocnemius (GN) recession
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Alberta
Atrial Fibrillation, T2DM (Type 2 Diabetes Mellitus)
RE-ELECT. Dabigatran vs Warfarin in AF Patients With T2DM and CKD
Kidney function in patients with atrial fibrillation (AF) is tending to decline over a time which is clearly demonstrated in clinical studies.
- Conditions
- Atrial Fibrillation, T2DM (Type 2 Diabetes Mellitus), Chronic Kidney Diseases
- Trial name
- RE-ELECT (NCT03789695)
- Testing
- Dabigatran Etexilate
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Irina Ermolaeva
Chronic Stroke Patients
Combined Effect of Sensory Training With Bobath Therapy in Patients With Chronic Stroke
Chronic stroke causes moderate to severe impairments in proprioception, balance, and motor functions, which can impact upon an individual's ability to perform activities of daily living, leading to reduced quality of life and…
- Trial name
- NCT07139002
- Testing
- Bobath Therapy, Sensory Training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Stroke
Comparative Effects of Dual Task and PNF on Balance ,Cognition and Motor Function in Chronic Stroke Patients .
The aim of this study is to compare the effect of dual tasking and proprioceptive neuromuscular facilitation on balance, cognition and motor function in chronic stroke patients. It will be randomized clinical trial.
- Trial name
- NCT05931172
- Testing
- Dual tasking, PNF(proprioceptive neuromuscular facilitation exercises)
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Chronic Stroke
Robotic Rehabilitation Vs Occupational Therapy Chronic Stroke Upper Limb Rehabilitation
The functional recovery of the upper limb represents a critical element in post-stroke rehabilitation; hemiplegic/hemiparetic patients who achieve optimal recovery are a minority, and incomplete recovery has relevant consequences…
- Trial name
- REDIRECT (NCT06884553)
- Testing
- Robotic therapy (Gloreha Sinfonia system), Occupational therapy, Control
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- University of Florence
Stellate Ganglion Block
Stellate Ganglion Block in Complex Regional Pain Syndrome
The aim was to investigate the effect of Stellate Ganglion Blockade, which will be applied in addition to conventional physical therapy, on pain and functionality in patients with poststroke complex regional pain syndrome.
- Trial name
- NCT07129811
- Testing
- Stellate Ganglion Block
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara City Hospital Bilkent
Stroke
Evaluation of Sensorimotor Ankle Impairments in Chronic Stroke
The purpose of this study is to capture sensorimotor ankle function in a chronic stroke population through validation of novel, experimental metrics and their comparison with established, clinical measures of function.
- Trial name
- NCT06410989
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Ischemic Stroke
A Phase 2b Study of Dalfampridine 10mg Extended Release Tablet in Subjects With Chronic Deficits After Ischemic Stroke
This is a multi-center, safety and tolerability study in subjects with chronic stable sensorimotor deficits after ischemic stroke. It has been designed as a double-blind, placebo-controlled, 2-period crossover study.
- Trial name
- NCT01605825
- Where
- 20 sites in United States
- Volunteers
- 83 people
- Sponsor
- Acorda Therapeutics
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