Clinical trials: Stroke, Chronic
Hypertension, Stroke
A Cluster-Randomized Controlled Trial
The goal of this study is to learn if an AI-generated personalized health report combined with face-to-face guidance from cardiologists can help rural adults with high blood pressure control their blood pressure better and reduce…
- Conditions
- Hypertension, Stroke, Cardiovascular, Coronary Heart Disease
- Trial name
- NCT07845448
- Testing
- AI-powered personalized health report with cardiologist consultation and prescription optimization, Integrated management (follow-up, education, quality control) without AI report and cardiologist consultation
- Volunteers
- 14,400 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Stroke, Hemiparesis
Structural Neuroplasticity Associated With Aerobic Treadmill Training in Geriatric Chronic Stroke Survivors
Aerobic treadmill exercise has been shown to improve walking, cardiovascular fitness and thereby risk factor profiles in chronic stroke patients (Macko et al., Stroke 2005).
- Trial name
- NCT00614224
- Testing
- treadmill exercise training
- Volunteers
- 38 people
- Sponsor
- Andreas R Luft
Stroke, Stroke, Chronic
Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue
This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a stroke more than six months prior to enrolling.
- Conditions
- Stroke, Stroke, Chronic, Fatigue
- Trial name
- NCT05584124
- Testing
- High frequency repetitive transcranial magnetic stimulation
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development
Chronic Stroke
Universal Exercise Unit Therapy With Sling Exercise Therapy on Lower Limb Kinematics in Chronic Stroke Patients
Stroke occurred when blood supply to brain or a part of brain is disturbed due to clot (ischaemic stroke) or due rupture of small vessels (hemorrhagic stroke) in brain and causes bleeding in brain cells.
- Trial name
- NCT05033873
- Testing
- Universal Exercise Unit Therapy (UEU), Sling Exercise Therapt (SET), Routine Physical Therapy / Control Group
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Riphah International University
Stroke
Physiotherapy in Order to Improve Walking Capacity and Participation in Chronic Stroke Subjects
In hemiplegic stroke patients, gait performance is affected by impaired walking endurance. Evidence has shown that higher exercise intensity improves cardiovascular fitness, while greater dose in task repetition benefits…
- Trial name
- NCT02543450
- Testing
- Cardiovascular and task-oriented training, Upper limb strength training program
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- University of Valencia
Stroke, Middle Cerebral Artery Stroke
Dual-Task Training With Different Priority Instructional Sets on the Gait Parameters in Patients With Chronic Stroke
Balance is controlled through a complex process involving sensory, visual, vestibular and cerebral functioning which get affected by various neurological disorders such as in stroke.
- Conditions
- Stroke, Middle Cerebral Artery Stroke, Chronic Stroke
- Trial name
- NCT03752788
- Testing
- Dual-task Training Fixed Priority, Dual-task Training Variable Priority
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- King Saud University
Chronic Stroke
Constraint Induced Movement Therapy and Bilateral Training in Chronic Stroke
Stroke is a leading cause of long-term disability, with upper limb spasticity and impaired hand function being common problems in the chronic phase.
- Trial name
- CIMT-BT (NCT07378774)
- Testing
- CIMT, bilateral training
- Where
- Pakistan
- Volunteers
- 112 people
- Sponsor
- Zikra Azhar
Chronic Stroke Patients
Multimodal Gait Training With and Without Rhythmic Auditory Stimulation in Chronic Stroke Patients
The primary goal of this randomized clinical trial is to investigate the efficacy of multimodal gait training, with and without rhythmic auditory stimulation, in improving gait, coordination and reducing fall risk in individuals…
- Trial name
- NCT06696950
- Testing
- Mutimodal gait training includes unilateral step training, inclined treadmill training, over ground training with rhythmic auditory stimulation, Multimodal gait training
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Pain, Pain Syndrome
Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06071949
- Testing
- Adezunap
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Pediatrics, Muscle Spasticity
BOTOX® Open-Label Treatment in Pediatric Upper Limb Spasticity
This study will evaluate the long-term safety of BOTOX® (botulinum toxin Type A) for the treatment of pediatric upper limb spasticity.
- Conditions
- Pediatrics, Muscle Spasticity, Cerebral Palsy, Stroke
- Trial name
- NCT01603615
- Testing
- Botulinum Toxin Type A
- Where
- 48 sites in United States, Canada and 7 more
- Volunteers
- 220 people
- Sponsor
- Allergan
Stroke, Ischemic Stroke
Feasibility of a Remotely Delivered Step Count Intervention in Chronic Stroke
The goal of this study is to explore the feasibility of a new approach to rehabilitation that focuses on step count. Participants will complete 6 telephone or Zoom-based sessions with an occupational therapist over 6 weeks and…
- Conditions
- Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- PA-ChatS (NCT07649135)
- Testing
- Physical Activity Chats after Stroke (PA-ChatS)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Minnesota
Post Stroke, Post-Traumatic Headache
Aerobic Exercise and Transcranial Low Laser Therapy in Patients With Central Nervous System Injury
Objective of this protocol will be to evaluate the parameters related to the function of the musculoskeletal and cardiorespiratory system, through a rehabilitation and training program for people with acquired central nervous…
- Conditions
- Post Stroke, Post-Traumatic Headache, Spinal Injuries, Cerebral Palsy, Spastic
- Trial name
- NCT03751306
- Testing
- Transcranial Photobiomodulation, Cardiorespiratory Rehabilitation
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Universidade do Vale do Paraíba
Chronic Stroke
Transcranial Direct Current Stimulation Combined Neuromuscular Electrical Stimulation on Motor Recovery in Stroke
The purpose of this study was to investigate the effects of the combination treatment strategy. A randomized, double-blinded and sham-stimulation study was conducted.
- Trial name
- NCT04059848
- Testing
- tDCS(Intelect Mobile Stimulation and Combination, DJO, France), NMES(Enraf Nonius, Endomed-182, Netherlands)
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Chronic Stroke Patients
Mobile Applications for Exercise Adherence and Hand Function in Chronic Stroke.
Stroke is a clinically defined syndrome characterized by an acute, focal neurological deficit due to vascular damage in the central nervous system. It is the second leading cause of death and disability globally.
- Trial name
- NCT06696885
- Testing
- Mobile based video games and task based training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Stroke, Ischemic
The Effect of The Ten-Session Dual-tDCS On Lower-Limb Performance in Sub- Acute and Chronic Stroke
The present study aims to determine the effect of the ten-session dual tDCS combine with physical therapy on gait performance, balance, and lower limbs muscle strength in patients with subacute and chronic stroke.
- Trial name
- NCT04687033
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Stroke Patients
Short-term Effect of Using Non-immersive Gamified Exercises on Chronic Pain in People With Stroke.
Rehabilitation after stroke is essential to minimize permanent disability. Gamification of exercises has emerged as a promising strategy for increasing motivation and rehabilitation efficacy in people with stroke.
- Trial name
- NCT06863649
- Testing
- Gamified NON-IMMERSIVE VIRTUAL REALITY EXERCISES, video-based exercises
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Exeter
Hypertension, Dyslipidemia
Improved Delivery of Cardiovascular Care Through Outreach Facilitation
The aim of the proposed study is to implement and evaluate Outreach Facilitation as a means to increase the uptake of evidence-based practice for secondary prevention and management of patients with established CVD and…
- Conditions
- Hypertension, Dyslipidemia, Diabetes, Chronic Kidney Disease
- Trial name
- IDOCC (NCT00574808)
- Testing
- Outreach Facilitation implementing elements of the Chronic Care Model
- Where
- Canada
- Volunteers
- 194 people
- Sponsor
- C. T. Lamont Primary Care Research Centre
Consciousness Disorders, Disorders of Consciousness Due to Severe Brain Injury
Ultrasound Stimulation for Patients in a Disorder of Consciousness
The overall aim of this study is to develop an intervention that can help recovery in patients surviving severe brain injury but failing to fully recover.
- Trial name
- tFUS (NCT06939348)
- Testing
- The Brainsonix BX Pulsar 1002 was designed to deliver low-intensity focused ultrasound pulsations (LIFUP) to the human brain.
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Stroke
Evaluation of Diagnostic Criteria for Chronic Critical Limb Ischemia
Chronic critical limb ischemia (CCI) is the most severe clinical form of occlusive arterial disease. Its prognosis is terrible, mortality estimated at 50% in five years.
- Trial name
- CRIMI (NCT02834143)
- Testing
- No intervention
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Stroke, Hemiparesis After Stroke
Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower…
- Conditions
- Stroke, Hemiparesis After Stroke, Chronic Stroke Patients, Hemiplegia
- Trial name
- NIMBLE (NCT07073235)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Danderyd Hospital
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