Clinical trials: Stroke, Chronic
Motor Recovery
BreEStim for Motor Recovery in Chronic Stroke With Moderate Impairment After a Long-term Use (Pilot).
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with…
- Trial name
- NCT04752319
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cerebrovascular Accident, Cerebral Stroke
The Role of HMGB-1 in Chronic Stroke
The purpose of this study is to measure the presence of HMGB-1 and other proteins in the blood across five time points after stroke, and to determine if their presence correlates with rate of stroke recovery.
- Conditions
- Cerebrovascular Accident, Cerebral Stroke, Stroke, Acute
- Trial name
- NCT01705353
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- Northwell Health
Chronic Stroke
Brain Imaging Study of Brain Plasticity in Chronic Stroke Patients
In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.
- Trial name
- NCT03392519
- Testing
- Chronic stroke
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Samsung Medical Center
Stroke, Chronic Brain Injury
Automated Stereognosis to Treat Loss of Tactile Function After Brain Injury
Researchers aim to determine whether the ReTrieve system for tactile training can improve tactile function (sense of touch) in the hand after brain injury when used at home for 6 weeks.
- Conditions
- Stroke, Chronic Brain Injury, Peripheral Neuropathy
- Trial name
- ReTrieve (NCT05740553)
- Testing
- ReTrieve Automated Stereognosis System
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The University of Texas at Dallas
Stroke, Sensory Defect
The Effect of ıntensified Sensory-based Therapy on Upper Extremity Functions and Activities of Daily Living
Sensory dysfunction following stroke is a common condition. The deficiency in the somatosensory system negatively affects the learning of new motor skills by preventing feedback from the sensory system, and it can also cause…
- Trial name
- NCT05133219
- Testing
- Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kocaeli University
Stroke
Virtual Environment Rehabilitation for Chronic Stroke
More than half of individuals post-stroke have residual movement disabilities, including reduced mobility, balance, and increased risk of falling.
- Trial name
- VEHAB (NCT01414686)
- Testing
- Commercially-Available Interactive Video Games
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of South Carolina
Brain Injury, Sequelae
Hyperbaric Oxygen Therapy in Chronic Stable Brain Injury
The purpose of this study is to discover the feasibility of conducting clinical research in individuals with chronic sequelae following brain injury who are given hyperbaric oxygen.
- Conditions
- Brain Injury, Sequelae, Stroke, Anoxia
- Trial name
- HYBOBI (NCT00830453)
- Testing
- Hyperbaric oxygen therapy (HBO2)
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Intermountain Health Care, Inc.
Caregiver Stress, Caregiver Stress Syndrome
ACT Group for Family Caregivers of Stroke Survivors
The goal of this study is to evaluate the efficacy of group-based ACT intervention in improving the levels of psychological distress in caregivers of stroke survivors. The main questions it aims to answer are: 1.
- Conditions
- Caregiver Stress, Caregiver Stress Syndrome, Caregiver Burnout, Caregiver Distress
- Trial name
- NCT07528261
- Testing
- Group-based ACT Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Wright Institute
Cardiovascular Diseases, Stroke
Cohort in Qianwan New District, Ningbo
Our objective is to carry out research on prevention and control of noncommunicable chronic diseases, and establish a risk prediction mechanism for chronic diseases to promote early detection, early diagnosis and early treatment…
- Conditions
- Cardiovascular Diseases, Stroke, Non-Communicable Chronic Diseases
- Trial name
- NCT06387875
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Stroke
MyStroke in Chronic Stroke
This is a single-center randomized control trial assessing the impact of a personalized video-based educational platform on patients satisfaction and stroke knowledge in the context of chronic stroke.
- Trial name
- NCT06057753
- Testing
- MyStroke
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pennsylvania
Stroke
Xbox Kinect Virtual Reality and Motor Imagery on Lower Limb Function in Chronic Stroke Patients
As virtual reality has therapeutic benefits and improves motor learning by practicing exercises in environment that analogue and mimic occasions and events of real world, as VR is designed and tailored according to the need of…
- Trial name
- NCT05411653
- Testing
- Virtual reality training with motor imagery, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Chronic Stroke
Robotic Rehabilitation for Stroke Survivors
Pilot study on the physiological response of robotic rehabilitation therapy for improving the performance of activities of daily living of stroke patients
- Trial name
- NCT05417828
- Testing
- Emulation of Active Daily Living tasks with a robotic device (SPINDLE)
- Where
- United States
- Sponsor
- State University of New York at Buffalo
Stroke
Retaining Short-term Training Effects on Gait Adaptability in People With Stroke
Background: The majority of stroke survivors regain walking ability. However, the ability to adapt gait patterns to meet environmental demands remains impaired in a majority of people in the chronic phase after stroke.
- Trial name
- ATTAINS (NCT05825053)
- Testing
- Gait adaptability training, Home-based exercise training
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Sint Maartenskliniek
Chronic Neuropathic Pain, Post-Stroke Pain
Transcranial Magnetic Stimulation for Chronic Neuropathic Pain
Chronic neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system. It is highly prevalent, debilitating, and challenging to treat.
- Conditions
- Chronic Neuropathic Pain, Post-Stroke Pain, Trigeminal Neuralgia, Nerve Injury
- Trial name
- NCT05593237
- Testing
- High Frequency rTMS, Low Frequency rTMS
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Motor Recovery
BreEStim for Post-Stroke Motor Recovery
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with…
- Trial name
- NCT04750551
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke, Hemiparesis
Electrical Stimulation for Recovery of Ankle Dorsiflexion in Chronic Stroke Survivors
Ankle dorsiflexor weakness (paresis) is one of the most frequently persisting consequences of stroke. The purpose of this exploratory study is to compare two different treatments -- Contralaterally Controlled Neuromuscular…
- Conditions
- Stroke, Hemiparesis, Lower Extremity Paresis
- Trial name
- NCT01029912
- Testing
- Electrical stimulator
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- MetroHealth Medical Center
Sensorimotor Gait Disorder, Neurologic Ambulation Disorder
Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop
The objective of this study is to determine the effectiveness of the NESS L300 (L300) in improving gait parameters, function, and quality of life among stroke subjects (greater than or equal to 3 months post stroke)with drop foot.
- Conditions
- Sensorimotor Gait Disorder, Neurologic Ambulation Disorder, Gait, Drop Foot, Poststroke Hemiparesis
- Trial name
- L300 (NCT01138995)
- Testing
- Ness L300, Ankle-foot orthosis
- Where
- 11 sites in United States
- Volunteers
- 197 people
- Sponsor
- Bioness Inc
Hemiplegia
Mirror Therapy Combined With TENS for Motor Recovery in Paretic Upper Limbs of Chronic Stroke Patients
The aim of this study is to determine whether mirror therapy, applied in addition to bilateral upper extremity transcutaneous electrical nerve stimulation in patients with chronic stroke, has an additive effect on upper extremity…
- Trial name
- NCT06770712
- Testing
- Mirror therapy, Transcutaneous Electrical Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Stroke
Smartphone-based Balance Assessment System for Chronic Stroke
Background: Stroke is the 4th deadly disease in Taiwan, 2016. Long term disabilities, balance impairments and limitations of activities of daily living are common characteristics of stroke.
- Trial name
- NCT04040101
- Testing
- smartphone-based balance training system
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Stroke, Coronary Arterial Disease (CAD)
Algae Effects in Markers of Cardiovascular Risk and Gut Microbiome
The Western diet, rich in fat and sugar, contributes to cardiovascular risk and alters the body metabolism, specifically through the modulation of the microbiome.
- Conditions
- Stroke, Coronary Arterial Disease (CAD), Myocardial Infarction (MI), Diabetes Mellitus
- Trial name
- CALGUT (NCT07173062)
- Testing
- Spirulina Arthrospira platensis (microalgae), Gelidium corneum
- Where
- Portugal
- Volunteers
- 150 people
- Sponsor
- Universidade do Porto
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