Clinical trials: Stroke, Chronic
Stroke
Effects of Mhealth App on the Improvement of Upper Limb Function for Patients With Chronic Stroke
The main purpose is to develop a mobile health app that combines behavioral change technology and task-oriented exercise strategies to provide a technology-assisted training system for upper limb motor function in home stroke…
- Trial name
- NCT05216094
- Testing
- smart phone App, conventional rehabilitation
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Chronic Stroke
LSVT BIG for Chronic Stroke Rehabilitation
This study aims to explore if the LSVT BIG® - a motor learning based treatment program designed for rehabilitation of people with Parkinson's disease could be beneficial for chronic stroke rehabilitation.
- Trial name
- NCT03191422
- Testing
- LSVT BIG
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Ottawa
Aphasia, Stroke
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
The purpose of this study is to assess changes in language abilities of participants with chronic, post-stroke aphasia following an 8-week therapy period combined with brain stimulation.
- Trial name
- NCT04142866
- Testing
- Anodal transcranial direct current stimulation, Speech-Language Therapy (SLT)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- City University of New York
Chronic Troublesome Sialorrhea, Parkinson's Disease
Clinical Study to Investigate the Efficacy and Safety of Two Dose Levels of NT 201 Versus Placebo in Treating Chronic Troublesome Sialorrhea in Various Neurological Conditions
The objective of this study is to investigate the efficacy and safety of two different dose levels of NT 201 (75 U or 100 U per cycle), compared with placebo, in reducing the salivary flow rate, and the severity and frequency of…
- Conditions
- Chronic Troublesome Sialorrhea, Parkinson's Disease, Post-stroke, Traumatic Brain Injury
- Trial name
- SIAXI (NCT02091739)
- Testing
- IncobotulinumtoxinA (100 Units), IncobotulinumtoxinA (75 Units)
- Where
- 31 sites in Germany, Poland
- Volunteers
- 184 people
- Sponsor
- Merz Pharmaceuticals GmbH
Stroke
Effect of Bilateral TENS With TOT on Upper Limb Function in Patients With Chronic Stroke
On the basis that the combined use of Uni-TENS and TRT is an effective intervention in upper limb recovery, and the advantage of Bi-TENS eliciting extra neural pathway in the intact hemisphere to facilitate the motor recovery…
- Trial name
- NCT03112473
- Testing
- Task-orientated training, Transcutaneous electrical nerve stimulation (TENS)
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University
Cardiovascular Diseases, Heart Diseases
Lifestyle and Chronic Disease in College Alumni (Harvard Alumni Health Study)
To monitor the relationship of lifestyle variables, particularly exercise, to cardiovascular mortality, all-cause mortality, projected longevity and aging, and cardiovascular morbidity in a large cohort of college graduates.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Hypertension
- Trial name
- NCT00005169
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Stroke
Chiropractic Care Plus Physiotherapy Compared to Physiotherapy Alone in Chronic Stroke Patients
The Investigator recently conducted a study in patients who had suffered from a stroke where it investigated whether similar findings are observed following a single session of chiropractic care.36 The key findings from this…
- Trial name
- NCT03849794
- Testing
- Experimental Group, Control group
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Oropharyngeal Dysphagia, Stroke
Treatment of Chronic Post-stroke Oropharyngeal Dysphagia With Paired Stimulation
According WHO, oropharyngeal dysphagia (OD) is a prevalent post-stroke (PS) condition involving the digestive system (ICD-10: I69.391) and an independent risk factor for malnutrition and pulmonary infection; and leads to greater…
- Conditions
- Oropharyngeal Dysphagia, Stroke, Stroke, Complication, Swallowing Disorder
- Trial name
- ICI20/00117 (NCT05720871)
- Testing
- rTMS + capsaicin 150μM (natural TRPV1 agonist), tDCS + capsaicin 150μM (natural TRPV1 agonist)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital de Mataró
Stroke
Explore the Effects of Cortical Priming on Visuomotor Stepping Learning in Persons With Chronic Stroke
This research study aims to understand the relationship between brain stimulation and leg skill learning in both healthy adults and persons with chronic stroke.
- Trial name
- NCT06681207
- Testing
- anodal transcranial direct current stimulation (a-tDCS)
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Stroke
Functional Improvement in Subacute/Chronic Stroke Through Non-invasive Virtual-reality-Based Telerehabilitation
Stroke is the leading cause of disability in adults worldwide. Rehabilitation after a stroke is crucial, even after the acute phase: initially, it aims to recover the deficits caused by the stroke, but in the subacute/chronic…
- Trial name
- MUVITY (NCT07240948)
- Testing
- Non- immersive virtual reality (niVR)-based telerehabilitation home program
- Where
- Spain
- Volunteers
- 322 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Brain Injury, Vascular, Aphasia
Treatment of Grammatical Time Marking in Post-Stroke Aphasia
The study aims to assess an individual or self-administered computer therapy's effectiveness in grammatical time marking. The main objective is to examine whether the therapy improves grammatical time marking of inflected verbs…
- Conditions
- Brain Injury, Vascular, Aphasia, Stroke
- Trial name
- NCT05656638
- Testing
- Speech and language therapy
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- University of Neuchatel
Ischemic Stroke, Hemorrhagic Stroke
Effects of Transcranial Electrical Stimulation in Stroke Individuals
The present study will use transcranial electrical stimulation (tES) with conventional physical therapy in sub-acute (at least 2 weeks after stroke onset) to chronic stroke within 2 years to investigate the effect on cortical…
- Conditions
- Ischemic Stroke, Hemorrhagic Stroke, Chronic Stroke, Subacute Stroke
- Trial name
- NCT06134921
- Testing
- transcranial direct current stimulation (Active), transcranial alternating current stimulation (active), Conventional physical therapy program
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Stroke
Effect of Upper Extremity Rehabilitation Using Immersive Virtual Reality in Chronic Stroke Patients.
The study aimed to investigate the effect of exergames using virtual reality with head mounted device on motor recovery of upper extremities in chronic stroke patients.
- Trial name
- NCT05148052
- Testing
- Virtual reality exergames, Conventional occupational therapy
- Where
- 3 sites in South Korea
- Volunteers
- 15 people
- Sponsor
- Seoul National University Hospital
Stroke, Intervention
The Effectiveness and Mechanism of Character Strengths-based STEP Programme on Rehabilitation of Stroke Patients
There is an urgent need for educational and psychological adjustment to stimulate the post-stroke patients' motivation to actively carry out rehabilitation.
- Conditions
- Stroke, Intervention, Rehabilitation, Depression
- Trial name
- STEP (NCT05738499)
- Testing
- Character strengths-based structured treatment and education programme (CSSTEP), Structured treatment and education programme (STEP)
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Peking University
Stroke, Upper Extremity Paresis
Effects of Robot-Assisted Rehabilitation on Upper Extremity Functions in Chronic Stroke
The most common problem caused by stroke is motor activity limitation that reduces muscle movement and mobility. But stroke can also lead to sensory and cognitive impairment.
- Trial name
- NCT06306313
- Testing
- ReoGo, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Pamukkale University
Stroke, Occupational Therapy
Effects of Neuropilates on Rehabilitation Programs for Chronic Stroke
Introduction: Cerebrovascular damage (stroke) can generate motor or cognitive sequelae, making rehabilitation (such as the Pilates method) necessary to improve autonomy and quality of life.
- Conditions
- Stroke, Occupational Therapy, Physiotherapy
- Trial name
- NCT06127485
- Testing
- Neuropilates+occupational therapy and physiotherapy conventional, Occupational Therapy and Physiotherapy conventional
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Rey Juan Carlos
Cerebral Stroke, Hemiplegia, Spastic
Compensatory Kinematic Movements in Various Directions After Stroke
This is cross-sectional study. By comparing kinematic analysis between stroke and healthy subjects in various directions, this investigation analyzes the compensatory kinematic movement for reaching task in stroke survivors
- Trial name
- NCT05683158
- Where
- South Korea
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Healthy Subjects or Volunteers, Chronic Stroke
Investigating the Impact of Afferent Stimulation on Proprioceptive Function in Post-Stroke Rehabilitation
The objective of this study is to assess the functionality of a sensory stimulation device that uses mechanical vibrations and low-intensity electrical currents to deliver proprioceptive feedback to stroke patients regarding…
- Trial name
- NCT07073989
- Testing
- Afferent stimulation
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Julio S. Lora Millán
Chronic Stroke
Effects of Home-based vs. Clinic-based Rehabilitation on Sensorimotor, Cognition, Daily Function, and Participation
The purpose of this study was to compare the treatment effects of home-based or clinic-based bilateral training with and without mirror feedback programon on physiological markers, sensorimotor, cognition, daily functions, and…
- Trial name
- NCT02364232
- Testing
- bilateral training with and without mirror feedback
- Where
- 2 sites in Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Stroke Rehabilitation
COMPERATIVE EFFECTS of CONSTRAINT- INDUCED MOVEMENT THERAPY and MIRROR THERAPY on FUNCTIONAL AMBULATION and QUALITY of LIFE in CHRONIC STROKE PATIENTS
Stroke is a global health issue as this happens when the blood flow to the brain is disrupted or reduced, depriving the brain tissue of sugar and oxygen.
- Conditions
- Stroke, Stroke Rehabilitation, Mirror Therapy, Quality of Life (QOL)
- Trial name
- NCT06807814
- Testing
- Constraint-Induced Movement Therapy (CIMT)), Mirror Therapy
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- University of Lahore
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