Clinical trials: Stroke; Sequelae
Apathy, Stroke Sequelae
Accelerated rTMS for Post-Stroke Apathy
This pilot study will investigate the safety, feasibility, tolerability, and preliminary efficacy of accelerated high-dose repetitive transcranial magnetic stimulation (rTMS) targeting the medial prefrontal cortex (mPFC) to…
- Conditions
- Apathy, Stroke Sequelae, Stroke (CVA) or TIA, Stroke/Brain Attack
- Trial name
- NCT05878457
- Testing
- MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical University of South Carolina
Cerebrovascular Disease; Sequelae
Machines Assisting Recovery From Stroke
Locomotor disability remains a major obstacle to community function in stroke survivors. This disability is best characterized by the reduced gait speed and enhanced risk of falls that is observed in the majority of stroke…
- Trial name
- MARS (NCT02787694)
- Testing
- Factor Targeted Walking Training, treadmill
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Alabama at Birmingham
Stroke, Fatigue
Post-stroke Fatigue, Inflammation, tDCS
Fatigue is a common condition after an individual has a stroke. While the negative impacts of post-stroke fatigue are well known, the knowledge of the causes of post-stroke fatigue and effective treatments for post-stroke fatigue…
- Conditions
- Stroke, Fatigue, Chronic Stroke, Stroke Sequelae
- Trial name
- NCT05330988
- Testing
- anodal transcranial direct current stimulation (a-tDCS)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Stroke, Physical Inactivity
How Stroke Affects Leg Muscles When Walking
Stroke is the leading cause of acquired disability in France and the third leading cause worldwide. This research will : Test how reliable current medical methods are for measuring muscle activity.
- Conditions
- Stroke, Physical Inactivity, Spasticity, Muscle, Walking, Difficulty
- Trial name
- MCOACT (NCT07504627)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Limoges
Stroke Sequelae
ATFL Evaluation With Ultrasound in Stroke Patients
ATFL thickness increases on the affected side of stroke patients and the homogeneous fibrillar structure is deteriorated.We aim to compare morphology of ATFL and Achilles tendon on the affected and unaffected sides using…
- Trial name
- ATFL (NCT05792605)
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Stroke Sequelae, Neglect, Hemispatial
Virtual Reliability System for Visual Spatial Attention Evaluation in Stroke Patients
The researchers designed a software based on a head-mounted displays for virtual reality (HMD-VR) to evaluate the reaction time to stimuli presented at right or left visual field.
- Trial name
- NCT05332964
- Where
- Taiwan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Ischemic Stroke
Stem Cell Infusion in the Treatment of Patients with Neurological Sequelae After Ischemic Stroke
This trial is to investigate the safety and potential therapeutic efficacy of allogeneic administration of umbilical cord-derived MSCs (UC-MSCs) in combination with standard neurological complications after ischemic stroke…
- Trial name
- NCT05292625
- Testing
- UC-MSC infusion via intravenous route, UC-MSC infusion via intrathecal route, standard stroke treatment and rehabilitation therapy
- Where
- Vietnam
- Volunteers
- 48 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Stroke Sequelae, Stroke
Mental Practice in Post-stroke Subjects
Among the limitations caused by cerebrovascular accident (CVA), the upper limb (MS) undergoes changes that limit the individual in his ability to maintain an active social life.
- Trial name
- NCT03251209
- Testing
- Physical practice, Mental practice, Videotherapy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Stroke Sequelae
Sedentarism of Stroke Survivors in the Valencian Community and Development of a Self-management Program
Stroke is the third leading cause of disability worldwide. Women present a higher incidence of this pathology and prevalence of its risk factors.
- Trial name
- SEDMA_Stroke (NCT04576598)
- Testing
- Self-management program to increase physical activity levels, Education information
- Where
- 2 sites in Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Stroke Patients, Stroke
Young Stroke Service Deep Phenotyping: Exploring Recovery in Young Adult Survivors of Stroke
The Investigators are running a small, early-phase research study across several hospitals in Melbourne, Australia. The study will involve up to 100 young adults between the ages of 18 and 55 who have had a stroke.
- Conditions
- Stroke Patients, Stroke, Stroke; Sequelae, Young Adults
- Trial name
- NCT07019493
- Testing
- Observational Cohort
- Where
- 2 sites in Australia
- Volunteers
- 100 people
- Sponsor
- The Florey Institute of Neuroscience and Mental Health
Stroke Syndrome Sequela Spasticity
Perfetti Method on Upper Extremity Spasticity of Stroke Patient
This study objective is to study the immediate effect of Perfetti Method in reducing spasticity of upper extremity in stroke patients at the Department of Physical Medicine,Faculty of Medicine Ramathibodhi Hospital, Thailand.
- Trial name
- NCT04869748
- Testing
- Perfetti method, passive stretching
- Where
- Thailand
- Volunteers
- 14 people
- Sponsor
- Mahidol University
Stroke, Spastic Hemiparesis
Hand Rehabilitation Using Botulinum Toxin and Functional Electrical Stimulation-pilot Study
The investigator tried to find out possibility of functional improvement using botulinum toxin injection targeting finger flexor spasticity with functional electrical stimulation among chronic stroke patients who did not show any…
- Conditions
- Stroke, Spastic Hemiparesis, Spasticity as Sequela of Stroke
- Trial name
- NCT03549975
- Testing
- Botulinum Toxin Type A 100 unit/Vial (Product)
- Volunteers
- 20 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea
COPD, Heart Failure
Technology Assisted Nudging to Increase Physical Activity Among Hospitalised Medical Patients
Primary Objective To investigate if patients hospitalised for older adults with a decreased level of physical function, either related to a chronic condition e.g., COPD, Congestive heart failure, renal failure; infections…
- Conditions
- COPD, Heart Failure, Parkinson Disease, Arthritis
- Trial name
- SENS4ME (NCT06336252)
- Testing
- Digital nudging intervention target to change behavior
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Bispebjerg Hospital
Stroke Sequelae, Motor Skills Disorders
Cognitive-motor Training Post-stroke - a Pilot Randomized Controlled Trial
Stroke is a leading and growing cause of long-term adult disability. Up to 80% of stroke patients have impaired manual dexterity reducing their independence, return to work and quality of life.
- Trial name
- Cogmos (NCT06112574)
- Testing
- Visuomotor force control training
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Danderyd Hospital
Stroke Sequelae, Dependency
Evaluation of Degree of Dependency After Stroke.
Understanding the risk of dependence and its severity before hospital discharge for stroke is important for health and social care planning as instrument to prioritize people where the assistance is more appropriate in a context…
- Trial name
- NCT03451357
- Testing
- Dependence degree already certificated by Dependence Law.
- Where
- Spain
- Volunteers
- 230 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Arrhythmia, Atrial Fibrillation
Arterial Embolism After Catheter Ablation of Atrial Fibrillation. ATRIAL FIBRILLATION
The EMBOL-AF is a multicenter, international, observational study designed as a retrospective registry that will investigate the characteristics of systemic arterial embolic events after treatment of atrial fibrillation by…
- Conditions
- Arrhythmia, Atrial Fibrillation, Ablation, Stroke, Acute
- Trial name
- EMBOL-AF (NCT06134739)
- Testing
- No intervention.
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Hospital Universitario La Paz
Stroke, Depression
Can Acupuncture Treat Post-stroke Depression?
An 8-week, assessor-blind, randomized controlled trial will be conducted. A total of 138 patients with post-stroke depression (PSD) will be randomly assigned to the combination acupuncture treatment (CAI) (n = 69) or least…
- Conditions
- Stroke, Depression, Stroke Sequelae
- Trial name
- PSD2 (NCT02644161)
- Testing
- Dense cranial electroacupuncture stimulation, Body acupuncture, Antidepressant
- Where
- 2 sites in Hong Kong
- Volunteers
- 91 people
- Sponsor
- The University of Hong Kong
Stroke, Brain Ischemia
Use of Minocicline in Patients With Stroke
The investigators will evaluate the National Institute of Health Stroke Scale/Score (NIHSS)in patients with stroke, and then give Minocycline 100mg po every 12 hours or placebo for five days, then perform periodic evaluations to…
- Conditions
- Stroke, Brain Ischemia, Paralysis
- Trial name
- NCT01556802
- Testing
- Minocicline
- Where
- Colombia
- Volunteers
- 134 people
- Sponsor
- Hospital Universitario Hernando Moncaleano Perdomo
Stroke Sequelae
Telerehabilitation for Post-stroke Patients
In the last few years, there has been an increasing shift towards outpatients setting in the care of patients with stroke. Unfortunately, this led to a high percentage of discharged patients who did not receive an adequate amount…
- Trial name
- NCT04413240
- Testing
- Telerehabilitation, Conventional rehabilitation
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Universita di Verona